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H. Cuny · SciRah

Researcher profile · Semantic Scholar

H. Cuny

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H. Cuny — researcher profile on SciRah

h-index: 16
Works: 25
Citations: 968

Most-cited papers

High susceptibility to fatty liver disease in two-pore channel 2-deficient mice
C. Grimm, L. Holdt, Cheng-Chang Chen, Sami Hassan +22 more
2014Nature Communications196 citations Open access
Semantic Scholar
Switching off calcium-dependent inactivation in l-type calcium channels by an autoinhibitory domain
C. Wahl-Schott, L. Baumann, H. Cuny, C. Eckert +2 more
2006Proceedings of the National Academy of Sciences of the United States of America105 citations Open access
Semantic Scholar
A Screening Approach to Identify Clinically Actionable Variants Causing Congenital Heart Disease in Exome Data
J. Szot, H. Cuny, G. Blue, D. Humphreys +13 more
2018Circulation Genomic and Precision Medicine88 citations Open access
Semantic Scholar
Identification of clinically actionable variants from genome sequencing of families with congenital heart disease
Dimuthu Alankarage, E. Ip, J. Szot, Jacob T. Munro +17 more
2018Genetics in Medicine77 citations Open access
Semantic Scholar
NAD deficiency due to environmental factors or gene–environment interactions causes congenital malformations and miscarriage in mice
H. Cuny, Melissa Rapadas, Jessica M. Gereis, Ella M. M. A. Martin +3 more
2020Proceedings of the National Academy of Sciences of the United States of America59 citations Open access
Semantic Scholar
γ-Aminobutyric Acid Type B (GABAB) Receptor Expression Is Needed for Inhibition of N-type (Cav2.2) Calcium Channels by Analgesic α-Conotoxins*
H. Cuny, Andrew de Faoite, Thuan G. Huynh, T. Yasuda +2 more
2012Journal of Biological Chemistry57 citations Open access
Semantic Scholar
Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors.
Marco C. Inserra, S. Kompella, I. Vetter, A. Brust +6 more
2013Biochemical Pharmacology56 citations
Semantic Scholar
Identifying Key Amino Acid Residues That Affect α-Conotoxin AuIB Inhibition of α3β4 Nicotinic Acetylcholine Receptors*
A. Grishin, H. Cuny, A. Hung, R. J. Clark +5 more
2013Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Novel Mechanism of Voltage-Gated N-type (Cav2.2) Calcium Channel Inhibition Revealed through α-Conotoxin Vc1.1 Activation of the GABAB Receptor
Thuan G. Huynh, H. Cuny, P. Slesinger, David John Adams
2015Molecular Pharmacology44 citations Open access
Semantic Scholar
Differential Cav2.1 and Cav2.3 channel inhibition by baclofen and α-conotoxin Vc1.1 via GABAB receptor activation
G. Berecki, Jeffrey R. McArthur, H. Cuny, R. J. Clark +1 more
2014The Journal of General Physiology44 citations Open access
Semantic Scholar
Bi-Allelic Mutations in NADSYN1 Cause Multiple Organ Defects and Expand the Genotypic Spectrum of Congenital NAD Deficiency Disorders.
J. Szot, Carla Campagnolo, Ye Cao, K. Iyer +12 more
2019American Journal of Human Genetics43 citations Open access
Semantic Scholar
Calmodulin Is a Functional Regulator of Cav1.4 L-type Ca2+ Channels*
Kristina Griessmeier, H. Cuny, Katrin Rötzer, O. Griesbeck +3 more
2009Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Molecular Basis for Differential Sensitivity of α-Conotoxin RegIIA at Rat and Human Neuronal Nicotinic Acetylcholine Receptors
S. Kompella, H. Cuny, A. Hung, David John Adams
2015Molecular Pharmacology24 citations Open access
Semantic Scholar
Maternal heterozygosity of Slc6a19 causes metabolic perturbation and congenital NAD deficiency disorder in mice
H. Cuny, Kayleigh Bozon, Rosemary B. Kirk, Delicia Z. Sheng +2 more
2022Disease Models & Mechanisms23 citations Open access
Semantic Scholar
α‐Conotoxins active at α3‐containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition
H. Cuny, Rilei Yu, Han-Shen Tae, S. Kompella +1 more
2018British Journal of Pharmacology23 citations Open access
Semantic Scholar
Kv3.1 channels stimulate adult neural precursor cell proliferation and neuronal differentiation
T. Yasuda, H. Cuny, David John Adams
2013Journal of Physiology18 citations Open access
Semantic Scholar
Simultaneous quantification of 26 NAD-related metabolites in plasma, blood, and liver tissue using UHPLC-MS/MS.
H. Cuny, E. Kristianto, M. Hodson, S. Dunwoodie
2021Analytical Biochemistry16 citations
Semantic Scholar
Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins*
H. Cuny, S. Kompella, Han-Shen Tae, Rilei Yu +1 more
2016Journal of Biological Chemistry15 citations Open access
Semantic Scholar
γ -Aminobutyric Acid Type B (GABA B ) Receptor Expression is Needed for Inhibition of N-type (Ca v 2.2) Calcium Channels by Analgesic α -Conotoxins*
H. Cuny, A. Faoite, Thuan G. Huynh, T. Yasuda +2 more
20126 citations
Semantic Scholar
Actions of α-conotoxins on neuronal nicotinic acetylcholine receptors and synaptic transmission in rat parasympathetic ganglia
David John Adams, A. Harper, A. Grishin, H. Cuny
20131 citations
Semantic Scholar
Key Structural Determinants in the Agonist Binding Loops of Human (cid:2) 2 and (cid:2) 4 Nicotinic Acetylcholine Receptor Subunits Contribute to (cid:3) 3 (cid:2) 4 Subtype Selectivity of (cid:3) -Conotoxins
H. Cuny, S. Kompella, Han-Shen Tae, Rilei Yu +1 more
20200 citations
Semantic Scholar
2.2 Channels Modulates Channel Kinetics V N-Type Ca Alternative Splicing in the Voltage-Sensing Region of
S. McDonough, D. Lipscombe, G. Nicol, R. Khanna +11 more
20150 citations
Semantic Scholar
(Cuny et al., 2012). We also demonstrated Differential Ca v 2.1 and Ca v 2.3 channel inhibition by baclofen and
G. Berecki, Jeffrey R. McArthur, H. Cuny, Richard J. Clark +1 more
20140 citations
Semantic Scholar
1672-Pos Board B402 Using Exofacially Tagged Functional Cav2.2 to Investigate the Modulation of Pore Subunit Trafficking by Auxiliary Calcium Channel Subunits
Jeffrey R. McArthur, H. Cuny, R. J. Clark, David John Adams +4 more
20140 citations
Semantic Scholar
4 Nicotinic Acetylcholine Receptors β 3 α -Conotoxin AuIB Inhibition of α Affect Identifying Key Amino Acid Residues That Neurobiology:
David John Adams, K. Akondi, P. Alewood, R. J. Clark +3 more
20130 citations
Semantic Scholar

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