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R. Jurkowska · SciRah

Researcher profile · Semantic Scholar

R. Jurkowska

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R. Jurkowska — researcher profile on SciRah

h-index: 31
Works: 75
Citations: 6,604

Most-cited papers

Cyclical DNA methylation of a transcriptionally active promoter
R. Métivier, Rozenn Gallais, C. Tiffoche, Christine Le Péron +10 more
2008Nature927 citations
Semantic Scholar
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
D. Jia, R. Jurkowska, Xing Zhang, A. Jeltsch +1 more
2007Nature827 citations Open access
Semantic Scholar
Structure and Function of Mammalian DNA Methyltransferases
R. Jurkowska, T. Jurkowski, A. Jeltsch
2011ChemBioChem668 citations
Semantic Scholar
The Dnmt3a PWWP Domain Reads Histone 3 Lysine 36 Trimethylation and Guides DNA Methylation*
A. Dhayalan, A. Rajavelu, Philipp Rathert, R. Tamas +3 more
2010Journal of Biological Chemistry523 citations Open access
Semantic Scholar
Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail
Yingying Zhang, R. Jurkowska, Szabolcs Soeroes, A. Rajavelu +7 more
2010Nucleic Acids Research395 citations Open access
Semantic Scholar
New concepts in DNA methylation.
A. Jeltsch, R. Jurkowska
2014TIBS -Trends in Biochemical Sciences. Regular ed394 citations
Semantic Scholar
Protein lysine methyltransferase G9a acts on non-histone targets.
Philipp Rathert, A. Dhayalan, M. Murakami, Xing Zhang +6 more
2008Nature Chemical Biology341 citations Open access
Semantic Scholar
Efficient targeted DNA methylation with chimeric dCas9–Dnmt3a–Dnmt3L methyltransferase
Peter Stepper, G. Kungulovski, R. Jurkowska, T. Chandra +5 more
2016Nucleic Acids Research297 citations Open access
Semantic Scholar
Allosteric control of mammalian DNA methyltransferases – a new regulatory paradigm
A. Jeltsch, R. Jurkowska
2016Nucleic Acids Research188 citations Open access
Semantic Scholar
Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms
Linfeng Gao, Max Emperle, Yi-Ran Guo, Sara A. Grimm +16 more
2020Nature Communications169 citations Open access
Semantic Scholar
Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity.
A. N. Siddique, S. Nunna, A. Rajavelu, Yingying Zhang +6 more
2013Journal of Molecular Biology169 citations
Semantic Scholar
The UHRF1 Protein Stimulates the Activity and Specificity of the Maintenance DNA Methyltransferase DNMT1 by an Allosteric Mechanism*
P. Bashtrykov, G. Jankevicius, R. Jurkowska, S. Ragozin +1 more
2013Journal of Biological Chemistry131 citations Open access
Semantic Scholar
Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L
R. Jurkowska, Nils Anspach, C. Urbanke, D. Jia +4 more
2008Nucleic Acids Research119 citations Open access
Semantic Scholar
Mechanistic Insights on the Inhibition of C5 DNA Methyltransferases by Zebularine
Christine Champion, D. Guianvarc’h, C. Sénamaud-Beaufort, R. Jurkowska +4 more
2010PLoS ONE105 citations Open access
Semantic Scholar
Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase.
H. Gowher, P. Loutchanwoot, O. Vorobjeva, V. Handa +3 more
2006Journal of Molecular Biology101 citations
Semantic Scholar
Oligomerization and Binding of the Dnmt3a DNA Methyltransferase to Parallel DNA Molecules
R. Jurkowska, A. Rajavelu, Nils Anspach, C. Urbanke +4 more
2011Journal of Biological Chemistry97 citations Open access
Semantic Scholar
Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain.
P. Bashtrykov, G. Jankevicius, Anita Smarandache, R. Jurkowska +2 more
2012Chemistry and Biology96 citations Open access
Semantic Scholar
H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1
R. Jurkowska, S. Qin, G. Kungulovski, W. Tempel +13 more
2017Nature Communications87 citations Open access
Semantic Scholar
C5‐DNA Methyltransferase Inhibitors: From Screening to Effects on Zebrafish Embryo Development
A. Ceccaldi, A. Rajavelu, Christine Champion, C. Rampon +13 more
2011ChemBioChem77 citations
Semantic Scholar
Application of histone modification-specific interaction domains as an alternative to antibodies
G. Kungulovski, Ina Kycia, R. Tamas, R. Jurkowska +5 more
2014Genome Research63 citations Open access
Semantic Scholar
Function and disruption of DNA Methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation
A. Rajavelu, R. Jurkowska, J. Fritz, A. Jeltsch
2011Nucleic Acids Research63 citations Open access
Semantic Scholar
Rapid Synthesis of New DNMT Inhibitors Derivatives of Procainamide
L. Halby, Christine Champion, C. Sénamaud-Beaufort, Sophie Ajjan +11 more
2012ChemBioChem58 citations
Semantic Scholar
Enzymology of Mammalian DNA Methyltransferases.
R. Jurkowska, A. Jeltsch
2016Advances in Experimental Medicine and Biology49 citations
Semantic Scholar
Target specificity of mammalian DNA methylation and demethylation machinery.
M. Ravichandran, R. Jurkowska, T. Jurkowski
2018Organic and biomolecular chemistry48 citations Open access
Semantic Scholar
Cooperative DNA Binding and Protein/DNA Fiber Formation Increases the Activity of the Dnmt3a DNA Methyltransferase*
Max Emperle, A. Rajavelu, R. Reinhardt, R. Jurkowska +1 more
2014Journal of Biological Chemistry48 citations Open access
Semantic Scholar
The DNMT3A R882H mutant displays altered flanking sequence preferences
Max Emperle, A. Rajavelu, Stefan Kunert, P. Arimondo +3 more
2018Nucleic Acids Research46 citations Open access
Semantic Scholar
Mechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges.
R. Jurkowska, A. Jeltsch
2016Advances in Experimental Medicine and Biology44 citations Open access
Semantic Scholar
DNA methyltransferase assays.
R. Jurkowska, A. Ceccaldi, Yingying Zhang, P. Arimondo +1 more
2011Methods in molecular biology42 citations
Semantic Scholar
Application of DNA methyltransferases in targeted DNA methylation
A. Jeltsch, R. Jurkowska, T. Jurkowski, K. Liebert +2 more
2007Applied Microbiology and Biotechnology42 citations
Semantic Scholar
Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2
A. Rajavelu, Cristiana Lungu, Max Emperle, Michael Dukatz +11 more
2018Nucleic Acids Research37 citations Open access
Semantic Scholar
The DNMT3A R882H mutation does not cause dominant negative effects in purified mixed DNMT3A/R882H complexes
Max Emperle, Michael Dukatz, Stefan Kunert, Katharina Holzer +3 more
2018Scientific Reports34 citations Open access
Semantic Scholar
Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function
M. Ravichandran, Dominik Rafalski, C. Davies, O. Ortega-Recalde +21 more
2021bioRxiv31 citations Open access
Semantic Scholar
Approaches to Enzyme and Substrate Design of the Murine Dnmt3a DNA Methyltransferase
R. Jurkowska, A. N. Siddique, T. Jurkowski, A. Jeltsch
2011ChemBioChem30 citations
Semantic Scholar
High‐resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD
U. Schwartz, Maria Llamazares-Prada, S. Pohl, M. Richter +30 more
2023EMBO Journal28 citations Open access
Semantic Scholar
DNA Methyltransferases - Role and Function
A. Jeltsch, R. Jurkowska
2016Advances in Experimental Medicine and Biology27 citations
Semantic Scholar
Silencing of gene expression by targeted DNA methylation: concepts and approaches.
R. Jurkowska, A. Jeltsch
2010Methods in molecular biology26 citations
Semantic Scholar
Role of epigenetic mechanisms in the pathogenesis of chronic respiratory diseases and response to inhaled exposures: From basic concepts to clinical applications.
R. Jurkowska
2024Pharmacology and Therapeutics25 citations Open access
Semantic Scholar
Deoxyribonucleic acid methyl transferases 3a and 3b associate with the nuclear orphan receptor COUP-TFI during gene activation.
Rozenn Gallais, Florence Demay, P. Baráth, L. Finot +6 more
2007Molecular Endocrinology22 citations
Semantic Scholar
An ATPase-Deficient Variant of the SNF2 Family Member HELLS Shows Altered Dynamics at Pericentromeric Heterochromatin
Cristiana Lungu, K. Muegge, A. Jeltsch, R. Jurkowska
2015Journal of Molecular Biology21 citations Open access
Semantic Scholar
Multimerization of the dnmt3a DNA methyltransferase and its functional implications.
A. Jeltsch, R. Jurkowska
2013Progress in Molecular Biology and Translational Science16 citations
Semantic Scholar
Auto‐methylation of the mouse DNA‐(cytosine C5)‐methyltransferase Dnmt3a at its active site cysteine residue
A. N. Siddique, R. Jurkowska, T. Jurkowski, A. Jeltsch
2011The FEBS Journal15 citations
Semantic Scholar
EpiCRISPR targeted methylation of Arx gene initiates transient switch of mouse pancreatic alpha to insulin-producing cells
Marija Đorđević, Peter Stepper, Clarissa Feuerstein-Akgoz, C. Gerhauser +11 more
2023Frontiers in Endocrinology14 citations Open access
Semantic Scholar
Versatile workflow for cell type–resolved transcriptional and epigenetic profiles from cryopreserved human lung
Maria Llamazares-Prada, E. Espinet, V. Mijošek, U. Schwartz +23 more
2021JCI Insight14 citations Open access
Semantic Scholar
Mechanisms and Biological Roles of DNA Methyltransferases and DNA Methylation: From Past Achievements to Future Challenges.
R. Jurkowska, A. Jeltsch
2022Advances in Experimental Medicine and Biology12 citations
Semantic Scholar
Genomic imprinting--the struggle of the genders at the molecular level.
R. Jurkowska, A. Jeltsch
2013Angewandte Chemie12 citations
Semantic Scholar
H 3 K 14 ac is linked to methylation of H 3 K 9 by the triple Tudor domain of SETDB 1
R. Jurkowska, S. Qin, G. Kungulovski, W. Tempel +13 more
20179 citations
Semantic Scholar
A solid‐phase transfection platform for arrayed CRISPR screens
Ozdemirhan Sercin, S. Reither, Paris Roidos, N. Ballin +12 more
2019Molecular Systems Biology8 citations Open access
Semantic Scholar
Practical Considerations for Complex Tissue Dissociation for Single-Cell Transcriptomics.
S. Pohl, M. L. Prada, E. Espinet, R. Jurkowska
2023Methods in molecular biology6 citations
Semantic Scholar
Enzymology of Mammalian DNA Methyltransferases.
R. Jurkowska, A. Jeltsch
2022Advances in Experimental Medicine and Biology6 citations Open access
Semantic Scholar
Establishment, Erasure and Synthetic Reprogramming of DNA Methylation in Mammalian Cells
R. Jurkowska, T. Jurkowski
2019RNA Technologies5 citations
Semantic Scholar

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A. Jeltsch×39
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T. Jurkowski×14
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A. Rajavelu×11
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R. Reinhardt×9
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R. Tamas — researcher profile on SciRah

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