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Y. Vercoulen · SciRah

Researcher profile · Semantic Scholar

Y. Vercoulen

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Y. Vercoulen — researcher profile on SciRah

h-index: 16
Works: 43
Citations: 1,412

Most-cited papers

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.
J. van Loosdregt, Y. Vercoulen, T. Guichelaar, Y. Gent +8 more
2010Blood400 citations
Semantic Scholar
ERK-MAPK signaling opposes Rho-kinase to promote endothelial cell survival and sprouting during angiogenesis.
G. Mavria, Y. Vercoulen, Maggie Yeo, H. Paterson +4 more
2006Cancer Cell339 citations Open access
Semantic Scholar
Lactate controls cancer stemness and plasticity through epigenetic regulation.
N. B. Nguyen, Sira Gevers, R. Kok, L. Burgering +14 more
2025Cell Metabolism123 citations Open access
Semantic Scholar
Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1
J. Iwig, Y. Vercoulen, Rahul K. Das, Tiago F. Barros +6 more
2013eLife78 citations Open access
Semantic Scholar
Multiplex Tissue Imaging: Spatial Revelations in the Tumor Microenvironment
S. van Dam, M. Baars, Y. Vercoulen
2022Cancers59 citations Open access
Semantic Scholar
CD30 Discriminates Heat Shock Protein 60-Induced FOXP3+CD4+ T Cells with a Regulatory Phenotype
I. D. de Kleer, Y. Vercoulen, M. Klein, J. Meerding +6 more
2010Journal of Immunology40 citations Open access
Semantic Scholar
A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1
Y. Vercoulen, Y. Kondo, J. Iwig, Axel B. Janssen +5 more
2017eLife39 citations Open access
Semantic Scholar
Human Regulatory T Cell Suppressive Function Is Independent of Apoptosis Induction in Activated Effector T Cells
Y. Vercoulen, E. Wehrens, N. V. van Teijlingen, W. de Jager +2 more
2009PLoS ONE39 citations Open access
Semantic Scholar
Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells
Darienne R. Myers, E. Norlin, Y. Vercoulen, J. Roose
2019Cell Reports38 citations Open access
Semantic Scholar
Increased Presence of FOXP3+ Regulatory T Cells in Inflamed Muscle of Patients with Active Juvenile Dermatomyositis Compared to Peripheral Blood
Y. Vercoulen, F. Bellutti Enders, J. Meerding, M. Plantinga +13 more
2014PLoS ONE36 citations Open access
Semantic Scholar
Development of a Caco-2-based intestinal mucosal model to study intestinal barrier properties and bacteria–mucus interactions
E. Floor, Jinyi Su, Maitrayee Chatterjee, Elise S Kuipers +8 more
2024Gut microbes35 citations
Semantic Scholar
MATISSE: a method for improved single cell segmentation in imaging mass cytometry
M. Baars, N. Sinha, M. Amini, A. Pieterman-Bos +5 more
2021BMC Biology34 citations Open access
Semantic Scholar
Heat shock protein 60 reactive T cells in juvenile idiopathic arthritis: what is new?
Y. Vercoulen, N. V. van Teijlingen, I. D. de Kleer, S. Kamphuis +2 more
2009Arthritis Research & Therapy28 citations Open access
Semantic Scholar
Multiplex spatial omics reveals changes in immune-epithelial crosstalk during inflammation and dysplasia development in chronic IBD patients
M. Baars, E. Floor, Neeraj Sinha, J. T. ter Linde +9 more
2024iScience17 citations Open access
Semantic Scholar
Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity
M. Baars, Thera Douma, Dimitre R. Simeonov, Darienne R. Myers +11 more
2019bioRxiv17 citations Open access
Semantic Scholar
Ablation of liver Fxr results in an increased colonic mucus barrier in mice
N. Ijssennagger, Kristel S. van Rooijen, Stefanía Magnúsdóttir, J. M. Ramos Pittol +11 more
2021JHEP Reports16 citations Open access
Semantic Scholar
Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis
M. J. V. van Eijs, J. T. ter Linde, M. Baars, M. Amini +10 more
2023iScience14 citations Open access
Semantic Scholar
Conjunctival inflammation in dupilumab‐treated atopic dermatitis comprises a multicellular infiltrate with elevated T1/T17 cytokines: A case series study
D. Bakker, J. T. ter Linde, M. Amini, Lieneke F. M. Ariëns +5 more
2021Allergy. European Journal of Allergy and Clinical Immunology13 citations Open access
Semantic Scholar
MATISSE: An analysis protocol for combining imaging mass cytometry with fluorescence microscopy to generate single-cell data
D. Krijgsman, Neeraj Sinha, M. Baars, S. van Dam +2 more
2021STAR Protocols11 citations Open access
Semantic Scholar
Stromal localization of inactive CD8+ T cells in metastatic mismatch repair deficient colorectal cancer
E. Küçükköse, M. Baars, M. Amini, S. Schraa +8 more
2023bioRxiv8 citations Open access
Semantic Scholar
Application of cultured human regulatory T cells requires preclinical in vivo evaluation.
Y. Vercoulen, T. Guichelaar, J. Meerding, M. Emmelot +7 more
2012Journal of Allergy and Clinical Immunology8 citations
Semantic Scholar
Dietary cystine restriction increases the proliferative capacity of the small intestine of mice
Judith C. W. de Jong, Kristel S. van Rooijen, E. Stigter, M. C. Gülersönmez +7 more
2024PLoS ONE6 citations Open access
Semantic Scholar
Hepatoblastoma exhibits a predominantly myeloid immune landscape and reveals opportunities for macrophage targeted immunotherapy
D. Krijgsman, Lianne Kraaier, M. Verdonschot, Stephanie A. Schubert +8 more
2023bioRxiv4 citations Open access
Semantic Scholar
Publisher Correction to: MATISSE: a method for improved single cell segmentation in imaging mass cytometry
M. Baars, N. Sinha, M. Amini, A. Pieterman-Bos +5 more
2021BMC Biology4 citations Open access
Semantic Scholar
Protocol for Barcoding T Cells Combined with Timed Stimulations
Kayla R. Kulhanek, Darienne R. Myers, O. Ksionda, Y. Vercoulen +2 more
2020STAR Protocols3 citations Open access
Semantic Scholar
Human induced CD4+CD25+FOXP3+ regulatory T cells are suppressive in vitro, but fail to suppress inflammation in vivo
Y. Vercoulen, T. Guichelaar, J. Meerding, M. Emmelot +6 more
20113 citations Open access
Semantic Scholar
Analysis of experimental colorectal liver metastases identifies distinct proliferation-independent transcriptional programs in micro- versus macrometastases
N. A. Peters, Maria C. Heinz, E. Küçükköse, B. Viergever +9 more
2025Journal of Translational Medicine1 citations Open access
Semantic Scholar
Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor induced colitis
M. V. van Eijs, J. T. ter Linde, M. Baars, M. Amini +10 more
2023medRxiv1 citations Open access
Semantic Scholar
Liver-gut axis controls the colonic mucus barrier via hepatic FXR
N. Ijssennagger, Kristel S. van Rooijen, Stefanía Magnúsdóttir, J. M. Ramos Pittol +11 more
2021JHEP Reports1 citations Open access
Semantic Scholar
Inhibitory Nectin-2/TIGIT interactions between CD163+ macrophages and CD8+ T cells in spatially defined immune niches associate with poor outcomes in neuroblastoma
A. Borst, Francisca J. Bergsma, F. van den Ham, M. Verdonschot +11 more
2026bioRxiv0 citations Open access
Semantic Scholar
Dietary cystine restriction increases the proliferative capacity of the small intestine of mice
Judith C. W. de Jong, Kristel S. van Rooijen, E. Stigter, M. C. Gülersönmez +7 more
2023bioRxiv0 citations Open access
Semantic Scholar
Infiltrating suppressive myeloid cells dominate the pediatric hepatoblastoma tumor immune microenvironment
D. Krijgsman, Lianne Kraaier, M. Verdonschot, J. Leusen +2 more
2023Journal of Hepatology0 citations
Semantic Scholar
1667P Multiplexed spatial analysis by imaging mass cytometry to immunologically characterize checkpoint inhibitor colitis
M. V. van Eijs, J. T. ter Linde, M. Baars, M. Amini +6 more
2022Annals of Oncology0 citations Open access
Semantic Scholar
Author response: A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1
Y. Vercoulen, Y. Kondo, J. Iwig, Axel B. Janssen +5 more
20170 citations Open access
Semantic Scholar
Author response: Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1
J. Iwig, Y. Vercoulen, Rahul K. Das, Tiago F. Barros +6 more
20130 citations Open access
Semantic Scholar
Autoinhibited state of the Ras-specific exchange factor RasGRP1
J. Iwig, Y. Vercoulen, Rahul K. Das, Tiago F. Barros +6 more
20130 citations
Semantic Scholar
Structure of C-terminal coiled coil of RasGRP1
J. Iwig, Y. Vercoulen, Rahul K. Das, Tiago F. Barros +6 more
20130 citations
Semantic Scholar
Solution structure of RasGRP2 EF hands bound to calcium
J. Kuriyan, J. Iwig, Y. Vercoulen, Rahul K. Das +6 more
20130 citations
Semantic Scholar
CD4+FOXP3+ regulatory T cells are abundantly present in inflamed muscle of patients with juvenile dermatomyositis
Y. Vercoulen, E. Elst, J. Meerding, M. Plantinga +9 more
2011Pediatric Rheumatology Online Journal0 citations Open access
Semantic Scholar
Arthritis therapy: a role for regulatory T cells?
Y. Vercoulen, B. Prakken
20110 citations
Semantic Scholar
Regulatory Phenotype T Cells with a + CD 4 + 60-Induced FOXP 3 CD 30 Discriminates Heat Shock Protein
I. D. de Kleer, Y. Vercoulen, M. Klein, J. Meerding +6 more
20100 citations
Semantic Scholar
OR.42. Human Heat Shock Protein 60 Induces Differentiation of Cd4+Cd3//Q T-Cells Into Foxp3+Cd4+Cd25//0 Regulatory T-Cells
Y. Vercoulen, I. D. de Kleer, S. Kamphuis, H. de Jong +6 more
20060 citations
Semantic Scholar
Regulatory T cells in health and disease : putting the pieces together
Y. Vercoulen
20060 citations
Semantic Scholar

Frequent co-authors

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Rahul K. Das×5

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