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R. Budinsky · SciRah

Researcher profile · Semantic Scholar

R. Budinsky

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R. Budinsky — researcher profile on SciRah

h-index: 22
Works: 74
Citations: 2,589

Most-cited papers

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
P. Godoy, N. Hewitt, U. Albrecht, M. Andersen +89 more
2013Archives of Toxicology1,242 citations Open access
Semantic Scholar
Critical analysis of literature on low-dose synergy for use in screening chemical mixtures for risk assessment
A. Boobis, R. Budinsky, S. Collie, K. Crofton +11 more
2011Critical Reviews in Toxicology155 citations
Semantic Scholar
Mode of action and dose–response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study
R. Budinsky, D. Schrenk, T. Simon, M. van den Berg +10 more
2014Critical Reviews in Toxicology80 citations
Semantic Scholar
Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice.
J. Harrill, R. Hukkanen, Marie Lawson, G. D. Martin +6 more
2013Toxicology and Applied Pharmacology80 citations
Semantic Scholar
A pilot study of oral bioavailability of dioxins and furans from contaminated soils: Impact of differential hepatic enzyme activity and species differences.
R. Budinsky, J. Rowlands, S. Casteel, Genevieve M. Fent +5 more
2008Chemosphere64 citations
Semantic Scholar
The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor.
R. Becker, G. Patlewicz, T. Simon, J. Rowlands +1 more
2015Regulatory toxicology and pharmacology : RTP53 citations Open access
Semantic Scholar
The challenge of using read-across within the EU REACH regulatory framework; how much uncertainty is too much? Dipropylene glycol methyl ether acetate, an exemplary case study.
N. Ball, M. Bartels, R. Budinsky, J. Klapacz +3 more
2014Regulatory toxicology and pharmacology : RTP53 citations
Semantic Scholar
The human AHR: identification of single nucleotide polymorphisms from six ethnic populations
C. Rowlands, D. Staskal, B. Gollapudi, R. Budinsky
2010Pharmacogenetics & Genomics43 citations
Semantic Scholar
Development of a method for the determination of total bisphenol a at trace levels in human blood and urine and elucidation of factors influencing method accuracy and sensitivity.
D. Markham, J. Waechter, R. Budinsky, W. Gries +8 more
2010Journal of Analytical Toxicology41 citations Open access
Semantic Scholar
Mortality Rates Among Workers Exposed to Dioxins in the Manufacture of Pentachlorophenol
J. Collins, K. Bodner, L. Aylward, M. Wilken +4 more
2009Journal of Occupational and Environmental Medicine40 citations
Semantic Scholar
Dapsone-induced hemolytic anemia: role of glucose-6-phosphate dehydrogenase in the hemolytic response of rat erythrocytes to N-hydroxydapsone.
S. Grossman, R. Budinsky, D. Jollow
1995Journal of Pharmacology and Experimental Therapeutics39 citations
Semantic Scholar
The formation of procainamide hydroxylamine by rat and human liver microsomes.
R. Budinsky, S. M. Roberts, E. Coats, Louis E. Adams +1 more
1987Drug Metabolism And Disposition33 citations
Semantic Scholar
Body mass index and serum chlorinated dibenzo-p-dioxin and dibenzofuran levels.
J. Collins, K. Bodner, C. Burns, R. Budinsky +4 more
2007Chemosphere29 citations
Semantic Scholar
Vapor–Liquid Equilibria of Alternative Refrigerants by Molecular Dynamics Simulations
M. Lísal, R. Budinsky, V. Vacek, Karel Aim
199929 citations
Semantic Scholar
Recommended relative potency factors for 2,3,4,7,8-pentachlorodibenzofuran: the impact of different dose metrics.
R. Budinsky, D. Paustenbach, D. Fontaine, B. Landenberger +1 more
2006Toxicological Sciences28 citations
Semantic Scholar
Immunomodulatory effects of procainamide metabolites: their implications in drug-related lupus.
L. Adams, C. Sanders, R. Budinsky, R. Donovan-Brand +2 more
1989Journal of Laboratory and Clinical Medicine28 citations
Semantic Scholar
Mechanism-based common reactivity pattern (COREPA) modelling of aryl hydrocarbon receptor binding affinity
P. I. Petkov, J. Rowlands, R. Budinsky, B. Zhao +2 more
2010SAR and QSAR in environmental research (Print)26 citations Open access
Semantic Scholar
Serum dioxin levels in former chlorophenol workers
J. Collins, R. Budinsky, C. Burns, L. Lamparski +3 more
2006Journal of Exposure Science and Environmental Epidemiology26 citations Open access
Semantic Scholar
Vapour-liquid equilibria for dipolar two-centre Lennard-Jones fluids by Gibbs-Duhem integration
M. Lísal, R. Budinsky, V. Vacek
199726 citations
Semantic Scholar
Extensive metabolism and route-dependent pharmacokinetics of bisphenol A (BPA) in neonatal mice following oral or subcutaneous administration.
D. Draganov, D. Markham, D. Beyer, J. Waechter +6 more
2015Toxicology25 citations Open access
Semantic Scholar
Effects of black carbon and montmorillonite clay on multiphasic hexachlorobenzene desorption from sediments.
Y. Chai, Xiu-Jin Qiu, John W. Davis, R. Budinsky +2 more
2007Chemosphere25 citations
Semantic Scholar
An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor-interacting protein (AIP) gene.
J. Rowlands, J. Urban, D. Wikoff, R. Budinsky
2011Drug Metabolism and Pharmacokinetics23 citations
Semantic Scholar
Comparative temporal toxicogenomic analysis of TCDD- and TCDF-mediated hepatic effects in immature female C57BL/6 mice.
A. N'jai, D. Boverhof, Edward Dere, L. Burgoon +5 more
2008Toxicological Sciences20 citations
Semantic Scholar
PCBs and neurodevelopmental effects in Michigan children: an evaluation of exposure and dose characterization.
J. Schell, R. Budinsky, M. J. Wernke
2001Regulatory toxicology and pharmacology : RTP20 citations
Semantic Scholar
A Comparison of Environment Classification Among Premium Hearing Instruments
Anusha Yellamsetty, Erol J. Ozmeral, R. Budinsky, D. Eddins
2021Trends in Hearing19 citations Open access
Semantic Scholar
Quantitative analysis of unconjugated and total bisphenol A in human urine using solid-phase extraction and UPLC-MS/MS: method implementation, method qualification and troubleshooting.
B. Buscher, D. van de Lagemaat, W. Gries, D. Beyer +6 more
2015Journal of chromatography. B, Analytical technologies in the biomedical and life sciences19 citations Open access
Semantic Scholar
Effects of aging and sediment composition on hexachlorobenzene desorption resistance compared to oral bioavailability in rats.
Y. Chai, John W. Davis, S. Saghir, Xiu-Jin Qiu +2 more
2008Chemosphere19 citations
Semantic Scholar
Dioxin Male Rat Reproductive Toxicity Mode of Action and Relative Potency of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and 2,3,7,8-Tetrachlorodibenzofuran Characterized by Fetal Pituitary and Testis Transcriptome Profiling.
K. Johnson, Julie K. Passage, Hui Lin, S. Sriram +1 more
2020Reproductive Toxicology18 citations
Semantic Scholar
Toxicokinetics of 2,3,7,8-TCDF and 2,3,4,7,8-PeCDF in mink (Mustela vison) at ecologically relevant exposures.
M. Zwiernik, S. Bursian, L. Aylward, D. Kay +7 more
2008Toxicological Sciences18 citations
Semantic Scholar
Hematotoxicity: Chemically Induced Toxicity of the Blood
R. Budinsky
200318 citations
Semantic Scholar
Chlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyl profiles of workers with trichlorophenol and pentachlorophenol exposures.
J. Collins, K. Bodner, S. Haidar, M. Wilken +5 more
2008Chemosphere16 citations
Semantic Scholar
Vapor-liquid equilibria of alternative refrigerants and their binaries by molecular simulations employing the reaction Gibbs ensemble Monte Carlo method
R. Budinsky, V. Vacek, M. Lísal
200416 citations
Semantic Scholar
An updated lymphohematopoietic and bladder cancers risk evaluation for occupational and environmental exposures to 1,3-butadiene.
C. Valdez-Flores, N. Erraguntla, R. Budinsky, S. Cagen +1 more
2022Chemico-Biological Interactions15 citations Open access
Semantic Scholar
Immunological characterization of the aryl hydrocarbon receptor (AHR) knockout rat in the presence and absence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
Ashwini S. Phadnis-Moghe, Wei-Min Chen, Jinpeng Li, Robert B. Crawford +10 more
2016Toxicology15 citations
Semantic Scholar
Transcriptional profiles induced by the Aryl Hydrocarbon Receptor agonists 2,3,7,8-tetrachlorodibenzo-p-dioxin, 2,3,7,8-tetrachlorodibenzofuran and 2,3,4,7,8-pentachlorodibenzofuran in primary rat hepatocytes.
J. C. Rowlands, R. Budinsky, B. Gollapudi, R. Novak +3 more
2011Chemosphere13 citations
Semantic Scholar
Estimates of cancer potency of 2,3,4,7,8-pentachlorodibenzofuran using both nonlinear and linear approaches.
T. Simon, C. Kirman, L. Aylward, R. Budinsky +2 more
2008Toxicological Sciences13 citations Open access
Semantic Scholar
Nonlinear responses for chromosome and gene level effects induced by vinyl acetate monomer and its metabolite, acetaldehyde in TK6 cells
R. Budinsky, B. Gollapudi, R. Albertini, R. Valentine +8 more
2013Environmental and Molecular Mutagenesis12 citations
Semantic Scholar
An integrated assessment of the 1,4-dioxane cancer mode of action and threshold response in rodents.
M. Lafranconi, Janet K. Anderson, R. Budinsky, Lisa M. Corey +3 more
2023Regulatory toxicology and pharmacology : RTP11 citations Open access
Semantic Scholar
Automated dose-response analysis of the relative hepatic gene expression potency of TCDF in C57BL/6 mice.
L. Burgoon, Q. Ding, A. N'jai, Edward Dere +5 more
2009Toxicological Sciences11 citations Open access
Semantic Scholar
A 90-day drinking water study in mice to characterize early events in the cancer mode of action of 1,4-dioxane.
M. Lafranconi, R. Budinsky, Lisa M. Corey, J. Klapacz +4 more
2020Regulatory toxicology and pharmacology : RTP10 citations Open access
Semantic Scholar
Hepatic P450 Enzyme Activity, Tissue Morphology and Histology of Mink (Mustela vison) Exposed to Polychlorinated Dibenzofurans
Jeremy N. Moore, J. Newsted, M. Hecker, M. Zwiernik +9 more
2009Archives of Environmental Contamination and Toxicology10 citations Open access
Semantic Scholar
Factors related to dioxin and furan body levels among Michigan workers.
C. Burns, J. Collins, R. Budinsky, K. Bodner +4 more
2008Environmental Research10 citations
Semantic Scholar
Procainamide acetylation in strains of rat and mouse.
S. M. Roberts, R. Budinsky, Louis E. Adams, A. Litwin +1 more
1985Drug Metabolism And Disposition10 citations
Semantic Scholar
Analytical methods impact estimates of trichloroethylene's glutathione conjugation and risk assessment.
Fa-Gen Zhang, S. Marty, R. Budinsky, M. Bartels +7 more
2018Toxicology Letters9 citations
Semantic Scholar
An Evaluation of Single Nucleotide Polymorphisms in the Human Heat Shock Protein 90 kDa Alpha and Beta Isoforms
J. Urban, R. Budinsky, J. Rowlands
20129 citations
Semantic Scholar
Single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene.
J. Urban, R. Budinsky, J. Rowlands
2011Drug Metabolism and Pharmacokinetics9 citations
Semantic Scholar
A genomics-based analysis of relative potencies of dioxin-like compounds in primary rat hepatocytes.
J. Rowlands, R. Budinsky, B. Gollapudi, Michael B. Black +6 more
2013Toxicological Sciences8 citations
Semantic Scholar
A reproductive and developmental toxicity screening study of 1,3-butadiene in Sprague-Dawley rats.
M. Marty, N. Erraguntla, C. North, Wade T. Barranco +6 more
2021Regulatory toxicology and pharmacology : RTP7 citations
Semantic Scholar
Trichloroethylene in drinking water throughout gestation did not produce congenital heart defects in Sprague Dawley rats
J. DeSesso, P. Coder, R. G. York, R. Budinsky +5 more
2019Birth Defects Research7 citations Open access
Semantic Scholar
Application of qualitative and quantitative uncertainty assessment tools in developing ranges of plausible toxicity values for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin
D. Wikoff, L. Haws, Caroline L Ring, R. Budinsky
2019Journal of Applied Toxicology7 citations Open access
Semantic Scholar

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