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S. Kolitz · SciRah

Researcher profile · Semantic Scholar

S. Kolitz

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S. Kolitz — researcher profile on SciRah

h-index: 16
Works: 56
Citations: 961

Most-cited papers

Reconstitution of yeast translation initiation.
M. Acker, S. Kolitz, Sarah F. Mitchell, J. Nanda +1 more
2007Methods in Enzymology152 citations
Semantic Scholar
Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2.GTP.Met-tRNA(i)(Met) ternary complex availability.
F. Robert, Lee D Kapp, S. Khan, M. Acker +7 more
2006Molecular Biology of the Cell134 citations Open access
Semantic Scholar
Kinetic and thermodynamic analysis of the role of start codon/anticodon base pairing during eukaryotic translation initiation.
S. Kolitz, Julie E. Takacs, J. Lorsch
2008RNA: A publication of the RNA Society86 citations Open access
Semantic Scholar
Advanced bioinformatics rapidly identifies existing therapeutics for patients with coronavirus disease-2019 (COVID-19)
Jason Kim, Jenny Y. Zhang, Yoonjeong Cha, S. Kolitz +6 more
2020Journal of Translational Medicine80 citations Open access
Semantic Scholar
Pridopidine activates neuroprotective pathways impaired in Huntington Disease
M. Geva, Rebecca Kusko, H. Soares, Kevin D. Fowler +14 more
2016Human Molecular Genetics78 citations Open access
Semantic Scholar
Microfluidic Probe for Single-Cell Lysis and Analysis in Adherent Tissue Culture
A. Sarkar, S. Kolitz, D. Lauffenburger, Jongyoon Han
2014Nature Communications76 citations Open access
Semantic Scholar
Eukaryotic Initiator tRNA: Finely Tuned and Ready for Action
S. Kolitz, J. Lorsch
2010FEBS Letters63 citations Open access
Semantic Scholar
Detecting Kinase Activities from Single Cell Lysate Using Concentration-Enhanced Mobility Shift Assay
L. Cheow, A. Sarkar, S. Kolitz, D. Lauffenburger +1 more
2014Analytical Chemistry47 citations Open access
Semantic Scholar
Yeast initiator tRNA identity elements cooperate to influence multiple steps of translation initiation.
Lee D Kapp, S. Kolitz, J. Lorsch
2006RNA: A publication of the RNA Society42 citations Open access
Semantic Scholar
Measurement and Modeling of Signaling at the Single-Cell Level
S. Kolitz, D. Lauffenburger
2012Biochemistry40 citations Open access
Semantic Scholar
Pharmacogenomics strategies to optimize treatments for multiple sclerosis: Insights from clinical research
I. Grossman, V. Knappertz, D. Laifenfeld, C. Ross +7 more
2017Progress in neurobiology31 citations
Semantic Scholar
Conserved residues in yeast initiator tRNA calibrate initiation accuracy by regulating preinitiation complex stability at the start codon
Jin-Sheng Dong, Antonio M. Muñoz, S. Kolitz, A. Saini +4 more
2014Genes & Development30 citations Open access
Semantic Scholar
Functional effects of the antigen glatiramer acetate are complex and tightly associated with its composition.
Tal H. Hasson, S. Kolitz, F. Towfic, D. Laifenfeld +12 more
2016Journal of Neuroimmunology22 citations Open access
Semantic Scholar
Leveraging existing data sets to generate new insights into Alzheimer’s disease biology in specific patient subsets
Kevin D. Fowler, J. Funt, M. Artyomov, B. Zeskind +2 more
2015Scientific Reports20 citations Open access
Semantic Scholar
Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids
S. Kolitz, Tal H. Hasson, F. Towfic, J. Funt +13 more
2015Scientific Reports19 citations Open access
Semantic Scholar
Physicochemical, biological, functional and toxicological characterization of the European follow-on glatiramer acetate product as compared with Copaxone
Sigal Melamed-Gal, P. Loupe, B. Timan, V. Weinstein +20 more
2018eNeurologicalSci17 citations Open access
Semantic Scholar
Compositional differences between Copaxone and Glatopa are reflected in altered immunomodulation ex vivo in a mouse model
I. Grossman, S. Kolitz, A. Komlosh, B. Zeskind +15 more
2017Annals of the New York Academy of Sciences7 citations Open access
Semantic Scholar
1524P Preliminary phase I safety and activity of IMM-1-104, an orally dosed universal RAS inhibitor that drives deep cyclic inhibition of the MAPK pathway at MEK, in patients with advanced unresectable or metastatic solid tumors
V. Chung, A. Spira, A. Pavlick, D. Sommerhalder +13 more
2024Annals of Oncology5 citations
Semantic Scholar
AN INTEGRATED MICROFLUIDIC PROBE FOR CONCENTRATION-ENHANCED SELECTIVE SINGLE CELL KINASE ACTIVITY MEASUREMENT
A. Sarkar, S. Kolitz, L. Cheow, D. Lauffenburger +1 more
20113 citations
Semantic Scholar
Explanatory chapter: nucleic acid concentration determination.
S. Kolitz, J. Lorsch
2013Methods in Enzymology2 citations
Semantic Scholar
Dual-MEK Inhibitor Atebimetinib Displays Broad Activity in RAS- and RAF-Mutant Tumors via Deep Cyclic Inhibition and Resisting RAF Bypass
S. Kolitz, Anna Travesa, Amy Axel, J. Funt +7 more
2026Cancer Research1 citations Open access
Semantic Scholar
449 Cyclic disruption of the mitogen-activated protein kinase (MAPK) pathway by the dual MEK inhibitor, IMM-6-415, enhances PD1 and CTLA4 checkpoint blockade in RAS mutant tumors
Brett Hall, Anna Travesa, A. Yamamura, A. Axel +8 more
2022Regular and Young Investigator Award Abstracts1 citations Open access
Semantic Scholar
477 Deep learning to drive COVID-19 rapid drug repurposing
S. Kolitz, Jason Kim, Jenny Y. Zhang, Yoonjeong Cha +5 more
2020Journal for ImmunoTherapy of Cancer1 citations Open access
Semantic Scholar
664 Applying advanced data analysis to immunotherapy drug discovery for Uveal Melanoma
S. Kolitz, Yoonjeong Cha, Sailaja Battula, Rebecca Kusko +2 more
20201 citations Open access
Semantic Scholar
Abstract 5177: Metastasis: Leveraging transcriptomics to identify potential therapeutics
Matthew H. Ung, J. Funt, A. Lysaght, Jenny Y. Zhang +6 more
2018Tumor Biology1 citations
Semantic Scholar
Abstract 1509: Cachexia: Leveraging transcriptomics to identify potential therapeutics
Matthew H. Ung, Kevin Fowler, J. Funt, Renan Escalante-Chong +4 more
2018Molecular and Cellular Biology / Genetics1 citations
Semantic Scholar
Response to the Letter-to-the Editor by Cohen et al. concerning our eNeurologicalSci article, Melamed-Gal, et al. Physicochemical, biological, functional and toxicological characterization of the European follow-on glatiramer acetate product as compared with Copaxone. eNeurologicalSci 2018;12:19–30.
Sigal Melamed-Gal, P. Loupe, B. Timan, V. Weinstein +14 more
2018eNeurologicalSci1 citations Open access
Semantic Scholar
Physicochemical and Biological Characterization of both Copaxone and the European Follow-On Glatiramer Acetate Product (P1.400)
B. Timan, A. Komlosh, Olga Beriozkin, A. Kónya +16 more
2018Neurology1 citations
Semantic Scholar
Investigating the role of the initiator tRNA in start codon recognition during eukaryotic translation initiation
S. Kolitz
20101 citations
Semantic Scholar
Abstract 1873: Atebimetinib’s deep cyclic inhibition of MEK constrains MAPK-axis adaptive and acquired alterations in patients with RAS-mutant tumors.
Jason S. Kim, J. Funt, Jenny Zhang, S. Kolitz +5 more
2026Cancer Research0 citations
Semantic Scholar
Abstract A134: Atebimetinib Reduces Tumor Volume and Preserves Body Mass: A Dual Mechanism for Extended Survival in Pancreatic Cancer
Peter Vu, Vincent Chung, Gregory P. Botta, Daniel H. Ahn +9 more
2026Cancer Research0 citations
Semantic Scholar
Abstract 4195: Activity of IMM-1-104 alone or in combination with chemotherapy in RAS-altered pancreatic cancer models
Peter King, J. Funt, S. Kolitz, Praveen Nair +10 more
2024Cancer Research0 citations
Semantic Scholar
Abstract A134: Predicting activity of IMM-1-104 as single agent and in combination for patients with RAS or RAF mutant tumors
Praveen Nair, S. Kolitz, J. Funt, J. D. de Jong +11 more
2023Molecular Cancer Therapeutics0 citations
Semantic Scholar
Abstract A093: Deep Cyclic Inhibition of the MAPK pathway with IMM-6-415, alone and in combination with encorafenib, demonstrates anti-tumor activity and tolerability in RAF mutant tumors in vivo
Anna Travesa, Mai Johnson, Peter King, Praveen Nair +8 more
2023Molecular Cancer Therapeutics0 citations
Semantic Scholar
Abstract 4265: Humanized 3D tumor models that are mutationally aligned with AACR GENIE patients predict IMM-1-104 activity in RAS-addicted tumors
Praveen Nair, S. Kolitz, J. Funt, Peter King +8 more
2023Cancer Research0 citations
Semantic Scholar
Abstract B021: Pan-RAS IMM-1-104 activity in humanized 3D tumor models is independent of specific amino acid substitution
S. Kolitz, Praveen Nair, Mai Johnson, J. Funt +9 more
2023Molecular Cancer Research0 citations
Semantic Scholar
Translational modeling for patients with RAS mutant tumors: Profiling the dual-MEK inhibitor IMM-1-104 in a humanized 3D assay.
B. Hall, Praveen Nair, Kevin Fowler, A. Axel +5 more
2022Journal of Clinical Oncology0 citations
Semantic Scholar
Abstract P252: IMM-1-104: a novel, oral, selective dual-MEK inhibitor that displays broad antitumor activity and high tolerability across RAS and RAF mutant tumors in vivo
Peter King, Kevin D. Fowler, S. Kolitz, S. Barrett +2 more
2021Poster Presentations - Proffered Abstracts0 citations
Semantic Scholar
Abstract P254: Transcriptional effects in C26 tumor highlight mechanistic aspects of a novel dual MEK inhibitor, IMM-1-104
S. Kolitz, Kevin D. Fowler, Peter J. King, B. Zeskind +1 more
2021Poster Presentations - Proffered Abstracts0 citations
Semantic Scholar
Abstract P240: Benchmarking the novel dual-MEK inhibitor, IMM-1-104, head-to-head and in combination with sotorasib (AMG-510) in the MIA PaCa-2 (KRAS-G12C) pancreatic cancer xenograft model
Peter King, A. Axel, Kevin D. Fowler, S. Kolitz +3 more
2021Poster Presentations - Proffered Abstracts0 citations
Semantic Scholar
P3-055: SYSTEMS BIOLOGY PLATFORM TO ENABLE NEUROINFLAMMATORY TARGET ID, VALIDATION, AND PATIENT SELECTION FOR DISEASE-MODIFYING ALZHEIMER'S DISEASE THERAPEUTICS
T. A. Miller, L. H. Martens, Kelley C. Larson, J. Levenson +9 more
2019Alzheimer's & Dementia0 citations
Semantic Scholar
Integrated Transcriptomic and Physicochemical Characterization of Glatiramer Acetate Products (Copaxone and Glatopa) Available in the United States (P1.370)
A. Komlosh, D. Laifenfeld, S. Kolitz, Kevin Fowler +17 more
2018Neurology0 citations
Semantic Scholar
Defining Glatiramer Acetate: The USA Definition of Sameness and the EU Definition of Similarity (P3.415)
Sigal Melamed-Gal, P. Loupe, I. Grossman, B. Zeskind +6 more
2018Neurology0 citations
Semantic Scholar
Abstract B027: A meta-metastasis analysis identifies pan-cancer markers and therapeutic targets
Kevin Fowler, J. Funt, S. Kolitz, Jenny Y. Zhang +6 more
2018Metastasis and Invasion0 citations
Semantic Scholar
Abstract 789: Leveraging transcriptomic and genomic data to better select models for preclinical oncology therapeutic development to identify cell lines most similar to patient tumors
Yoonjeong Cha, Adam Labradorf, J. Perez-Rogers, B. Haas +9 more
2016Bioinformatics and Systems Biology0 citations
Semantic Scholar
Leveraging transcriptomic data to pinpoint mechanisms of gemcitabine resistance and potential combination therapies for pancreatic cancer.
Rebecca Kusko, Yoonjeong Cha, J. Perez-Rogers, Nacho Caballero +10 more
20160 citations
Semantic Scholar
Abstract 4741: Improving pancreatic cancer drug discovery by leveraging genomics to select better in vitro models
Yoonjeong Cha, A. Lysaght, R. Cui, B. Weiner +8 more
20150 citations
Semantic Scholar
Improving pre-clinical screening of drug candidates for pancreatic cancer by applying a systems genomics approach to pinpoint ideal cell line models.
B. Zeskind, Yoonjeong Cha, A. Lysaght, R. Cui +8 more
20150 citations
Semantic Scholar
Abstract A78: Leveraging genomics to optimize models for accelerated pancreatic cancer drug development
Yoonjeong Cha, A. Lysaght, B. Weiner, S. Kolitz +6 more
20150 citations
Semantic Scholar
Protein filter binding.
S. Kolitz, J. Lorsch
2014Methods in Enzymology0 citations
Semantic Scholar

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