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D. Laifenfeld · SciRah

Researcher profile · Semantic Scholar

D. Laifenfeld

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D. Laifenfeld — researcher profile on SciRah

h-index: 19
Works: 38
Citations: 1,690

Most-cited papers

Drug repurposing from the perspective of pharmaceutical companies
Yoonjeong Cha, T. Erez, I. J. Reynolds, D. Kumar +9 more
2018British Journal of Pharmacology362 citations Open access
Semantic Scholar
An artificial intelligence algorithm for prostate cancer diagnosis in whole slide images of core needle biopsies: a blinded clinical validation and deployment study.
L. Pantanowitz, G. Quiroga-Garza, Lilach Bien, Ronen Heled +9 more
2020The Lancet Digital Health312 citations Open access
Semantic Scholar
Mitochondria, synaptic plasticity, and schizophrenia.
D. Ben-Shachar, D. Laifenfeld
2004International review of neurobiology193 citations
Semantic Scholar
Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor
J. Kaye, V. Piryatinsky, Tal Birnberg, Tal Hingaly +15 more
2016Proceedings of the National Academy of Sciences of the United States of America135 citations Open access
Semantic Scholar
Validation and real-world clinical application of an artificial intelligence algorithm for breast cancer detection in biopsies
J. Sandbank, G. Bataillon, Alon Nudelman, Ira Krasnitsky +11 more
2022npj Breast Cancer100 citations Open access
Semantic Scholar
Norepinephrine alters the expression of genes involved in neuronal sprouting and differentiation: relevance for major depression and antidepressant mechanisms
D. Laifenfeld, E. Klein, D. Ben-Shachar
2002Journal of Neurochemistry76 citations Open access
Semantic Scholar
Rab5 Mediates an Amyloid Precursor Protein Signaling Pathway That Leads to Apoptosis
D. Laifenfeld, L. Patzek, D. McPhie, Yuzhi Chen +3 more
2007Journal of Neuroscience68 citations Open access
Semantic Scholar
Alterations in cell adhesion molecule L1 and functionally related genes in major depression: a postmortem study.
D. Laifenfeld, R. Karry, E. Klein, D. Ben-Shachar
2005Biological Psychiatry62 citations
Semantic Scholar
The Role of Hypoxia in 2-Butoxyethanol–Induced Hemangiosarcoma
D. Laifenfeld, A. Gilchrist, D. Drubin, Milena Jorge +11 more
2009Toxicological Sciences46 citations Open access
Semantic Scholar
Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse
Rebecca Kusko, Jennifer Dreymann, Jermaine Ross, Yoonjeong Cha +10 more
2018Molecular Neurodegeneration35 citations Open access
Semantic Scholar
Blood-based identification of non-responders to anti-TNF therapy in rheumatoid arthritis
Ty M. Thomson, R. Lescarbeau, David A. Drubin, D. Laifenfeld +5 more
2015BMC Medical Genomics34 citations Open access
Semantic Scholar
Pharmacogenomics strategies to optimize treatments for multiple sclerosis: Insights from clinical research
I. Grossman, V. Knappertz, D. Laifenfeld, C. Ross +7 more
2017Progress in neurobiology31 citations
Semantic Scholar
Emulated Clinical Trials from Longitudinal Real-World Data Efficiently Identify Candidates for Neurological Disease Modification: Examples from Parkinson’s Disease
D. Laifenfeld, C. Yanover, Michal Ozery-Flato, O. Shaham +4 more
2020Frontiers in Pharmacology26 citations Open access
Semantic Scholar
A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis
C. Ross, F. Towfic, Jyoti Shankar, D. Laifenfeld +8 more
2017Genome Medicine26 citations Open access
Semantic Scholar
Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury.
D. Laifenfeld, Luping Qiu, Rachel L Swiss, Jennifer Park +4 more
2014Toxicological Sciences26 citations Open access
Semantic Scholar
ATF2, A Member of the CREB/ATF Family of Transcription Factors, in Chronic Stress and Consequent to Antidepressant Treatment: Animal Models and Human Post-Mortem Brains
D. Laifenfeld, R. Karry, E. Grauer, E. Klein +1 more
2004Neuropsychopharmacology25 citations
Semantic Scholar
Functional effects of the antigen glatiramer acetate are complex and tightly associated with its composition.
Tal H. Hasson, S. Kolitz, F. Towfic, D. Laifenfeld +12 more
2016Journal of Neuroimmunology22 citations Open access
Semantic Scholar
Early patient stratification and predictive biomarkers in drug discovery and development: a case study of ulcerative colitis anti-TNF therapy.
D. Laifenfeld, David A. Drubin, Natalie L. Catlett, Jennifer Park +5 more
2012Advances in Experimental Medicine and Biology21 citations
Semantic Scholar
Targeting Tumor Cells with Anti-CD44 Antibody Triggers Macrophage-Mediated Immune Modulatory Effects in a Cancer Xenograft Model
D. Maisel, Fabian Birzele, E. Voss, Adam Nopora +6 more
2016PLoS ONE20 citations Open access
Semantic Scholar
Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids
S. Kolitz, Tal H. Hasson, F. Towfic, J. Funt +13 more
2015Scientific Reports19 citations Open access
Semantic Scholar
Systems diagnostics: anticipating the next generation of diagnostic tests based on mechanistic insight into disease.
D. Fryburg, Diane H. Song, D. Laifenfeld, D. de Graaf
2014Drug Discovery Today18 citations
Semantic Scholar
Physicochemical, biological, functional and toxicological characterization of the European follow-on glatiramer acetate product as compared with Copaxone
Sigal Melamed-Gal, P. Loupe, B. Timan, V. Weinstein +20 more
2018eNeurologicalSci17 citations Open access
Semantic Scholar
Compositional differences between Copaxone and Glatopa are reflected in altered immunomodulation ex vivo in a mouse model
I. Grossman, S. Kolitz, A. Komlosh, B. Zeskind +15 more
2017Annals of the New York Academy of Sciences7 citations Open access
Semantic Scholar
Genetika+: precision medicine solutions for mental health.
C. Albeldas, Niv Cohen, Sari Natan, N. Askari +2 more
2022Pharmacogenomics (London)3 citations Open access
Semantic Scholar
Biobanking in Israel 2016–17; expressed perceptions versus real life enrollment
G. Koren, D. Beller, D. Laifenfeld, I. Grossman +1 more
2017BMC Medical Ethics2 citations Open access
Semantic Scholar
A Novel Mechanistic Biomarker Panel Predicts Response to Infliximab in Patients with Crohn's Disease: P‐118
M. Macoritto, V. Hoang, Ty M. Thomson, D. Laifenfeld +1 more
20122 citations Open access
Semantic Scholar
Abstract C58: Causal Network™ Modeling identifies common and unique mechanisms for sensitivity to the PI3K inhibitor GSK1059615 and the AKT inhibitor GSK690693
M. Macoritto, D. Laifenfeld, Natalie L. Catlett, Milena Jorge +3 more
20092 citations
Semantic Scholar
Response to the Letter-to-the Editor by Cohen et al. concerning our eNeurologicalSci article, Melamed-Gal, et al. Physicochemical, biological, functional and toxicological characterization of the European follow-on glatiramer acetate product as compared with Copaxone. eNeurologicalSci 2018;12:19–30.
Sigal Melamed-Gal, P. Loupe, B. Timan, V. Weinstein +14 more
2018eNeurologicalSci1 citations Open access
Semantic Scholar
Loss of the Sigma-1 receptor disrupts pridopidine-induced gene expression (P4.048)
Jennifer Dreymann, M. Geva, Jermaine Ross, Yoonjeong Cha +6 more
2018Neurology1 citations
Semantic Scholar
Laquinimod targets the aryl hydrocarbon receptor (AhR) pathway in periphery and brains of naïve and EAE mice (P2.365)
Tal Birnberg, J. Kaye, Kevin Fowler, B. Weiner +9 more
2017Neurology1 citations
Semantic Scholar
1027 A Single Biomarker Panel Predicts Response to Infliximab in Patients With Crohn's Disease and Ulcerative Colitis
W. Westra, V. Hoang, D. Laifenfeld
20131 citations Open access
Semantic Scholar
Abstract PD11-04: A multi-feature AI-based solution for cancer diagnosis in breast biopsies: A prospective blinded multi-site clinical study
A. Vincent-Salomon, G. Bataillon, Alon Nudelman, J. Sandbank +9 more
2022Cancer Research0 citations
Semantic Scholar
AI VS. MICROSCOPE IN PRIMARY DIAGNOSIS: NOVEL AI-BASED SOLUTION INCREASES THE EFFICIENCY AND ACCURACY OF PROSTATE BIOPSIES REPORTING
D. Raoux, F. Tanguy, V. Rouleau, J. Terrier +11 more
2022Journal of Pathology Informatics0 citations Open access
Semantic Scholar
Abstract 867: Prostate cancer: AI-markers for detecting, grading, and prognosticating 5-year survival post-biopsy
D. Laifenfeld, Cobi Reouven, I. Gross, Ronen Heled +3 more
2020Clinical research0 citations
Semantic Scholar
Integrated Transcriptomic and Physicochemical Characterization of Glatiramer Acetate Products (Copaxone and Glatopa) Available in the United States (P1.370)
A. Komlosh, D. Laifenfeld, S. Kolitz, Kevin Fowler +17 more
2018Neurology0 citations
Semantic Scholar
Additional file 1: of Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse
Rebecca Kusko, Jennifer Dreymann, Jermaine Ross, Yoonjeong Cha +10 more
20180 citations
Semantic Scholar
A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis
C. Ross, F. Towfic, Jyoti Shankar, D. Laifenfeld +8 more
2017Genome Medicine0 citations Open access
Semantic Scholar
568 Therapeutic Diagnostic: Identification of Molecular Mechanisms Underlying Ulcerative Colitis in Infliximab Non-Responders at Baseline
M. Macoritto, Ty M. Thomson, Jennifer Park, D. Drubin +3 more
20120 citations
Semantic Scholar

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