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T. Guentert · SciRah

Researcher profile · Semantic Scholar

T. Guentert

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T. Guentert — researcher profile on SciRah

h-index: 21
Works: 72
Citations: 1,675

Most-cited papers

Utility of physiologically based pharmacokinetic models to drug development and rational drug discovery candidate selection.
F. Theil, T. Guentert, S. Haddad, P. Poulin
2003Toxicology Letters199 citations
Semantic Scholar
Pharmacokinetics of the new benzodiazepine antagonist Ro 15-1788 in man following intravenous and oral administration.
G. Roncari, W. Ziegler, T. Guentert
1986British Journal of Clinical Pharmacology131 citations Open access
Semantic Scholar
Moclobemide, a substrate of CYP2C19 and an inhibitor of CYP2C19, CYP2D6, and CYP1A2: A panel study *
L. Gram, T. Guentert, S. Grange, Kirsten Vistisen +1 more
1995Clinical pharmacology and therapy108 citations
Semantic Scholar
Influence of isolation procedure, extracellular matrix and dexamethasone on the regulation of membrane transporters gene expression in rat hepatocytes.
O. Luttringer, F. Theil, T. Lavé, Karin Wernli-Kuratli +2 more
2002Biochemical Pharmacology89 citations
Semantic Scholar
Convenient and sensitive high-performance liquid chromatography assay for ketoprofen, naproxen and other allied drugs in plasma or urine.
R. Upton, J. Buskin, T. Guentert, Rodger L. Williams +1 more
1980Journal of Chromatography A83 citations
Semantic Scholar
Physiologically based pharmacokinetic (PBPK) modeling of disposition of epiroprim in humans.
O. Luttringer, F. Theil, P. Poulin, A. Schmitt-Hoffmann +2 more
2003Journal of Pharmacy and Science75 citations
Semantic Scholar
Absorption and disposition of moclobemide in patients with advanced age or reduced liver or kidney function
K. Stoeckel, J. Pfefen, M. Mayersohn, M. Schoerlin +4 more
1990Acta Psychiatrica Scandinavica Supplementum62 citations
Semantic Scholar
Biotransformation of moclobemide in humans
R. Jauch, E. Griesser, G. Oesterhelt, W. Arnold +3 more
1990Acta Psychiatrica Scandinavica Supplementum61 citations
Semantic Scholar
Comparison of Equilibrium Times in Dialysis Experiments Using Spiked Plasma or Spiked Buffer
S. Øie, T. Guentert
198260 citations
Semantic Scholar
Clinical Pharmacokinetics of the Monoamine Oxidase-A Inhibitor Moclobemide
M. Mayersohn, T. Guentert
1995Clinical Pharmacokinetics56 citations
Semantic Scholar
Effect of saturable binding on the pharmacokinetics of drugs: a simulation
Svein Øie, T. Guentert, Thomas N. Tozer
1980The Journal of pharmacy and pharmacology48 citations
Semantic Scholar
Pharmacokinetics of tenoxicam in healthy human volunteers.
R. Heintz, T. Guentert, J. Enrico, U. Dubach +2 more
1984European journal of rheumatology and inflammation45 citations
Semantic Scholar
Biopharmaceutical evaluation of carprofen following single intravenous, oral, and rectal doses in dogs.
M. Schmitt, T. Guentert
1990Biopharmaceutics & drug disposition44 citations
Semantic Scholar
Clinical pharmacology of moclobemide during chronic administration of high doses to healthy subjects
J. Dingemanse, N. Wood, T. Guentert, S. Øie +2 more
1998Psychopharmacology39 citations
Semantic Scholar
Factors influencing the apparent protein binding of quinidine.
T. Guentert, Svein Øie
1982Journal of Pharmacy and Science36 citations
Semantic Scholar
Pharmacokinetics of benzodiazepines and of their metabolites
T. Guentert
198430 citations
Semantic Scholar
Pharmacokinetics of moclobemide after single and multiple oral dosing with 150 milligrams 3 times daily for 15 days
T. Guentert, G. Tucker, A. Korn, J. Pfefen +2 more
1990Acta Psychiatrica Scandinavica Supplementum28 citations
Semantic Scholar
The Pharmacology of Reversible Monoamine Oxidase Inhibitors
R. Amrein, S. Allen, T. Guentert, D. Hartmann +3 more
1989British Journal of Psychiatry27 citations
Semantic Scholar
Binding of Drugs in Milk: The Role of Casein in Milk Protein Binding
T. Stebler, T. Guentert
1990Pharmaceutical Research25 citations
Semantic Scholar
Effect of plasma protein binding on quinidine kinetics in the rabbit.
T. Guentert, S. Oie
1980Journal of Pharmacology and Experimental Therapeutics25 citations
Semantic Scholar
Monoamine oxidase-A: pharmacodynamics in humans of moclobemide, a reversible and selective inhibitor.
Nicholas H. G. Holford, T. Guentert, J. Dingemanse, L. Banken
1994British Journal of Clinical Pharmacology22 citations Open access
Semantic Scholar
Moclobemide: relationships between dose, drug concentration in plasma, and occurrence of adverse events.
T. Guentert, L. Banken, S. Hilton, N. Holford
1995Journal of Clinical Psychopharmacology21 citations
Semantic Scholar
Kinetics and electrocardiographic changes after oral 3‐OH‐quinidine in healthy subjects
S. Vožeh, T. Uematsu, T. Guentert, H. Ha +1 more
1985Clinical pharmacology and therapy21 citations
Semantic Scholar
Quinidine pharmacokinetics in man: Choice of a disposition model and absolute bioavailability studies
T. Guentert, N. Holford, Peter E. Coafes, R. Upton +1 more
1979Journal of pharmacokinetics and biopharmaceutics21 citations
Semantic Scholar
Pharmacokinetic and pharmacodynamic interactions between fluoxetine and moclobemide in the investigation of development of the “serotonin syndrome” *
J. Dingemanse, A. Wallnöfer, R. Gieschke, T. Guentert +1 more
1998Clinical pharmacology and therapy20 citations
Semantic Scholar
Pharmacodynamics of 3-hydroxyquinidine alone and in combination with quinidine in healthy persons.
S. Vožeh, Margrit Bindschedler, H. Ha, G. Kaufmann +2 more
1987American Journal of Cardiology20 citations
Semantic Scholar
Comparison of the pharmacokinetics of moclobemide in poor and efficient metabolizers of debrisoquine
M. P. Schoerlin, R. A. Blouin, J. P. Pfefen, T. Guentert
1990Acta Psychiatrica Scandinavica Supplementum19 citations
Semantic Scholar
Modification of the cardiovascular effects of ephedrine by the reversible monoamine oxidase A-inhibitor moclobemide.
J. Dingemanse, T. Guentert, Ronald Gieschke, M. Stabl
1996Journal of Cardiovascular Pharmacology18 citations Open access
Semantic Scholar
A Pharmacokinetic Model to Predict the PK Interaction of L-Dopa and Benserazide in Rats
S. Grange, N. Holford, T. Guentert
2001Pharmaceutical Research16 citations
Semantic Scholar
Disposition of vitamin K1 after intravenous and oral administration to subjects on phenprocoumon therapy
Svein Øie, D. Trenk, T. Guentert, H. Mosberg +1 more
198815 citations
Semantic Scholar
Specificity of quinidine determination methods.
T. Guentert, S. Riegelman
1978Clinical Chemistry15 citations
Semantic Scholar
Pharmacokinetics of quinidine and three of its metabolites in man
A. Rakhit, N. Holford, T. Guentert, K. Maloney +1 more
1984Journal of pharmacokinetics and biopharmaceutics14 citations
Semantic Scholar
Tenoxicam used as a parenteral formulation for acute pain in rheumatic conditions.
F. Jeunet, W. Enz, T. Guentert
1989Scandinavian Journal of Rheumatology. Supplement12 citations
Semantic Scholar
Overview on the pharmacokinetics of tenoxicam.
T. Guentert, R. Heintz, R. Joly
1987European journal of rheumatology and inflammation12 citations
Semantic Scholar
Pharmacodynamics of lazabemide, a reversible and selective inhibitor of monoamine oxidase B.
Nicholas H. G. Holford, T. Guentert, J. Dingemanse, R. Kettler
1994British Journal of Clinical Pharmacology11 citations Open access
Semantic Scholar
Interaction of mixed micelles formed from glycocholic acid and lecithin with the protein binding of various drugs.
T. Guentert, S. Oie, L. Paalzow, B. M. Frey +3 more
1987British Journal of Clinical Pharmacology11 citations Open access
Semantic Scholar
Time-Dependence in Benzodiazepine Pharmacokinetics Mechanisms and Clinical Significance
T. Guentert
1984Clinical Pharmacokinetics11 citations
Semantic Scholar
Evaluation of the absorption from some commercial sustained-release theophylline products
R. Upton, J. Thiercelin, T. Guentert, L. Sansom +3 more
1980Journal of pharmacokinetics and biopharmaceutics11 citations
Semantic Scholar
Moclobemide and fluvoxamine co‐administration: A prospective study in healty volunteers to investigate the potential development of the ‘serotonin syndrome’
A. Wallnöfer, T. Guentert, S. Eckernäs, J. Dingemanse
199510 citations
Semantic Scholar
Evaluation of a modified high-performance liquid chromatography assay for acebutolol and its major metabolite.
T. Guentert, G. Wientjes, R. Upton, D. Combs +1 more
1979Journal of Chromatography A10 citations
Semantic Scholar
Generics in transplantation medicine: Randomized comparison of innovator and substitution products containing mycophenolate mofetil
B. Reigner, S. Grange, D. Bentley, L. Banken +4 more
2019International journal of clinical pharmacology and therapeutics8 citations Open access
Semantic Scholar
The influence of cholestyramine on the elimination of tenoxicam and piroxicam
T. Guentert, R. Defoin, H. Mosberg
2004European Journal of Clinical Pharmacology8 citations
Semantic Scholar
Effect of age on the pharmacokinetics of tenoxicam in comparison to other non-steroidal anti-inflammatory drugs (NSAIDs).
M. Schmitt, T. Guentert
1989Scandinavian Journal of Rheumatology. Supplement8 citations
Semantic Scholar
Pharmacokinetics of Moclobemide in Male, Virgin Female, Pregnant and Nursing Rats
Svein øie, T. Guentert, Lorna Tolentino, G. Hermodsson
1992The Journal of pharmacy and pharmacology7 citations
Semantic Scholar
Bioavailability of intramuscularly administered tenoxicam
T. Stebler, T. Guentert
1993Biopharmaceutics & drug disposition6 citations
Semantic Scholar
UNALTERED IBUPROFEN-INDUCED FAECAL BLOOD LOSS UPON COADMINISTRATION OF MOCLOBEMIDE
T. Guentert, M. Schmitt, J. Dingemanse, L. Banken +2 more
1992Drug Metabolism and Drug Interactions6 citations
Semantic Scholar
Pharmacokinetics of tenoxicam in patients with impaired renal function
F. Horber, T. Guentert, E. Weidekamm, P. Heizmann +2 more
2004European Journal of Clinical Pharmacology5 citations
Semantic Scholar
Increase of plasma nonesterified fatty acid concentration and decrease of albumin binding affinity after intravenous injection of glycocholate-lecithin mixed micelles.
T. Guentert, B. M. Frey, E. Luedin, S. Heinzl +1 more
1990Journal of Laboratory and Clinical Medicine5 citations
Semantic Scholar
Altered quinidine disposition in a patient with chronic active hepatitis
J. Powell, K. Conrad, R. Okada, T. Guentert +1 more
1982Postgraduate medical journal5 citations Open access
Semantic Scholar
A single dose of azathioprine does not affect the pharmacokinetics of prednisolone following oral prednisone
F. J. Frey, F. Lozada, T. Guentert, B. Frey
1981European Journal of Clinical Pharmacology5 citations
Semantic Scholar

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