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Xiuquan Luo · SciRah

Researcher profile · Semantic Scholar

Xiuquan Luo

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Xiuquan Luo — researcher profile on SciRah

h-index: 21
Works: 36
Citations: 1,453

Most-cited papers

Superparamagnetic Iron Oxide Nanoparticles: Amplifying ROS Stress to Improve Anticancer Drug Efficacy
Gang Huang, Huabing Chen, Ying Dong, Xiuquan Luo +5 more
2013Theranostics288 citations Open access
Semantic Scholar
Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone
G. Chakrabarti, Zachary R. Moore, Xiuquan Luo, Mariya Ilcheva +11 more
2015Cancer & Metabolism110 citations Open access
Semantic Scholar
Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway
Qin He, Dong-Ik Lee, Rong Rong, Myounghee Yu +6 more
2002Oncogene98 citations
Semantic Scholar
The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism
Molly A. Silvers, S. Deja, N. Singh, Robert A. Egnatchik +7 more
2017Journal of Biological Chemistry80 citations Open access
Semantic Scholar
Transcriptional upregulation of PUMA modulates endoplasmic reticulum calcium pool depletion-induced apoptosis via Bax activation
Xiuquan Luo, Q. He, Ying Huang, M. Sheikh
2005Cell Death and Differentiation68 citations
Semantic Scholar
Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone
G. Chakrabarti, Molly A. Silvers, Mariya Ilcheva, Yuliang Liu +11 more
2015Scientific Reports62 citations Open access
Semantic Scholar
Genotoxic and endoplasmic reticulum stresses differentially regulate TRB3 expression
Chad A. Corcoran, Xiuquan Luo, Qin He, Chang-Ying Jiang +2 more
2005Cancer Biology & Therapy62 citations Open access
Semantic Scholar
Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells
Qin He, Xiuquan Luo, Ying Huang, M. Sheikh
2002Oncogene60 citations Open access
Semantic Scholar
Application of a proapoptotic peptide to intratumorally spreading cancer therapy
Renwei Chen, G. Braun, Xiuquan Luo, K. Sugahara +2 more
2012Cancer Research57 citations Open access
Semantic Scholar
Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation
Xiuquan Luo, Ying Huang, M. Sheikh
2003Oncogene57 citations
Semantic Scholar
ATM Regulates Insulin-Like Growth Factor 1-Secretory Clusterin (IGF-1-sCLU) Expression that Protects Cells against Senescence
Xiuquan Luo, Masatoshi Suzuki, S. Ghandhi, S. Amundson +1 more
2014PLoS ONE55 citations Open access
Semantic Scholar
ATM-dependent IGF-1 induction regulates secretory clusterin expression after DNA damage and in genetic instability
Eva M. Goetz, B. Shankar, Yuhua Zou, Julio C. Morales +5 more
2011Oncogene53 citations Open access
Semantic Scholar
Potential Tumor Suppressive Role of Monoglyceride Lipase in Human Colorectal Cancer
Hong Sun, Ling-Yan Jiang, Xiuquan Luo, Wei-Xin Jin +10 more
2012Oncogene50 citations Open access
Semantic Scholar
Celecoxib and a novel COX-2 inhibitor ON09310 upregulate death receptor 5 expression via GADD153/CHOP
Qin He, Xiuquan Luo, Wei-Xin Jin, Ying Huang +3 more
2008Oncogene50 citations
Semantic Scholar
Anoikis effector Bit1 negatively regulates Erk activity
Rania Kairouz-Wahbe, H. Biliran, Xiuquan Luo, IngWei Khor +5 more
2008Proceedings of the National Academy of Sciences of the United States of America45 citations Open access
Semantic Scholar
Preclinical Justification of pbi-shRNA EWS/FLI1 Lipoplex (LPX) Treatment for Ewing's Sarcoma
D. Rao, C. Jay, Zhao-Hui Wang, Xiuquan Luo +5 more
2016Molecular Therapy44 citations Open access
Semantic Scholar
DOC45, a Novel DNA Damage–Regulated Nucleocytoplasmic ATPase That Is Overexpressed in Multiple Human Malignancies
Hong Sun, Xiuquan Luo, J. Montalbano, Wei-Xin Jin +3 more
2010Molecular Cancer Research44 citations
Semantic Scholar
PDRG1, a novel tumor marker for multiple malignancies that is selectively regulated by genotoxic stress
Ling-Yan Jiang, Xiuquan Luo, Jingxue Shi, Hong Sun +3 more
2011Cancer Biology & Therapy42 citations Open access
Semantic Scholar
Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone
G. Chakrabarti, Zachary R. Moore, Xiuquan Luo, Mariya Ilcheva +11 more
2015Cancer & Metabolism31 citations Open access
Semantic Scholar
Cloning and characterization of a p53 and DNA damage down-regulated gene PIQ that codes for a novel calmodulin-binding IQ motif protein and is up-regulated in gastrointestinal cancers.
Xiuquan Luo, Qin He, Ying Huang, M. Sheikh
2005Cancer Research29 citations
Semantic Scholar
Prodrug Strategy to Achieve Lyophilizable, High Drug Loading Micelle Formulations Through Diester Derivatives of β-Lapachone
Xin-Peng Ma, Xiumei Huang, Gang Huang, Long-Shan Li +4 more
2014Advanced Healthcare Materials27 citations Open access
Semantic Scholar
Phase 1 Trial of Bi-shRNA STMN1 BIV in Refractory Cancer.
M. Barve, Zhao-Hui Wang, Padmasini Kumar, C. Jay +8 more
2015Molecular Therapy21 citations Open access
Semantic Scholar
KRAS mutant allele-specific expression knockdown in pancreatic cancer model with systemically delivered bi-shRNA KRAS lipoplex
D. Rao, Xiuquan Luo, Zhao-Hui Wang, C. Jay +5 more
2018PLoS ONE15 citations Open access
Semantic Scholar
A Scalable Engineered Extracellular Matrix Platform to Expand Tumor Cells
Seongjun Moon, Dylan B. Neale, Do Hoon Kim, Malini Mukherji +10 more
2023Advanced NanoBiomed Research3 citations Open access
Semantic Scholar
The NQO1 bioactivatable drug, (cid:2) -lapachone, alters the redox state of NQO1 (cid:3) pancreatic cancer cells, causing perturbation in central carbon metabolism
Molly A. Silvers, S. Deja, Naveen M. Singh, Robert A. Egnatchik +7 more
20201 citations
Semantic Scholar
Abstract 4614: β-lapachone suppresses glucose metabolism in a NQO1-dependent, tumor-selective manner.
Xiuquan Luo, Malina Patel, Long-Shan Li, R. DeBerardinis +1 more
20131 citations
Semantic Scholar
Abstract 3344: Inhibiting base excision repair synergistically enhances beta-lapachone-mediated ‘kiss of death’ for tumor-selective therapy of pancreatic cancer.
Xiuquan Luo, Long-Shan Li, Xiumei Huang, Lifen Cao +6 more
20131 citations
Semantic Scholar
Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFβ1 signaling to confer a pro-survival bystander effect
D. Klokov, Konstantin Leskov, S. Araki, Yonglong Zou +4 more
2012Oncogene1 citations Open access
Semantic Scholar
Abstract 787: DNA repair and metabolism inhibitors are tumor-selective when combined with NQO1 bioactivatable drugs for therapy against pancreatic and nonsmall cell lung cancers
Xiumei Huang, Zachary R. Moore, Xiuquan Luo, G. Chakrabarti +8 more
20140 citations
Semantic Scholar
Signal transduction processes in response to low dose ionizing radiation doses expected during space flight
Tracy Criswell, Eva M. Goetz, D. Klokov, Yonglong Zou +2 more
20130 citations
Semantic Scholar
Stress-induced Premature Promotes Prostate Cancer Growth and Metastasis through Alteration of Microenvironment
Xiuquan Luo, Masatoshi Suzuki, D. Boothman
20120 citations Open access
Semantic Scholar
Cellular Stress Responses to DNA Damage: An Intracellular Balance between Life, Senescence, and Death
Amy Rommel, Eva M. Goetz, Masatoshi Suzuki, S. Araki +9 more
20110 citations
Semantic Scholar
Low dose IR-induced IGF-1-sCLU expression: a p53-repressed, TGFß1-induced expression cascade that interferes with TGFß1 signaling to confer survival
D. Klokov, Konstantin Leskov, S. Araki, Yonglong Zou +4 more
20110 citations
Semantic Scholar
Abstract C33: N-terminal fragment of Bit1 apoptotic protein induces autophagy in tumor cells
Renwei Chen, G. Braun, Xiuquan Luo, K. Sugahara +2 more
20110 citations
Semantic Scholar
Low dose IR-induced IGF-1-sCLU expression: a p53-repressed expression cascade that interferes with TGFß1 signaling to confer survival
Dmitry Klokov, Konstantin Leskov, S. Araki, Yonglong Zou +4 more
20110 citations Open access
Semantic Scholar
PDRG, a novel tumor marker for colorectal cancer.
Ling-Yan Jiang, Xiuquan Luo, Jingxue Shi, Hong Sun +2 more
20080 citations
Semantic Scholar

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