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T. Richie · SciRah

Researcher profile · Semantic Scholar

T. Richie

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T. Richie — researcher profile on SciRah

h-index: 51
Works: 204
Citations: 11K

Most-cited papers

Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine
R. Seder, Lee-Jah Chang, Mary E. Enama, Kathryn L. Zephir +38 more
2013Science779 citations
Semantic Scholar
Sterile protection against human malaria by chemoattenuated PfSPZ vaccine
B. Mordmüller, G. Surat, H. Lagler, S. Chakravarty +28 more
2017Nature385 citations Open access
Semantic Scholar
Protection against malaria at 1 year and immune correlates following PfSPZ vaccination
A. Ishizuka, K. Lyke, A. Dezure, Andrea A. Berry +52 more
2016Nature Medicine347 citations Open access
Semantic Scholar
The March Toward Malaria Vaccines
S. Hoffman, J. Vekemans, T. Richie, P. Duffy
2015American Journal of Preventive Medicine207 citations Open access
Semantic Scholar
Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines
T. Richie, P. Billingsley, B. K. Sim, E. James +13 more
2015Vaccine171 citations Open access
Semantic Scholar
DNA Prime/Adenovirus Boost Malaria Vaccine Encoding P. falciparum CSP and AMA1 Induces Sterile Protection Associated with Cell-Mediated Immunity
I. Chuang, M. Sedegah, S. Cicatelli, M. Spring +42 more
2013PLoS ONE139 citations Open access
Semantic Scholar
First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers.
M. Spring, J. Murphy, R. Nielsen, M. Dowler +24 more
2013Vaccine134 citations
Semantic Scholar
Phase 1/2a Trial of Plasmodium vivax Malaria Vaccine Candidate VMP001/AS01B in Malaria-Naive Adults: Safety, Immunogenicity, and Efficacy
J. Bennett, A. Yadava, Donna M. Tosh, J. Sattabongkot +22 more
2016PLoS Neglected Tropical Diseases109 citations Open access
Semantic Scholar
Ethics of controlled human infection to address COVID-19
Seema K. Shah, F. Miller, T. Darton, Devan M. Duenas +18 more
2020Science106 citations
Semantic Scholar
Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity
Agnes Mwakingwe-Omari, S. Healy, Jacquelyn Lane, David Cook +32 more
2021Nature104 citations Open access
Semantic Scholar
Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial
M. Oneko, L. Steinhardt, Reuben Yego, R. Wiegand +26 more
2021Nature Medicine78 citations
Semantic Scholar
A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1
M. Roestenberg, J. Walk, Saskia C. van der Boor, M. Langenberg +25 more
2020Science Translational Medicine78 citations Open access
Semantic Scholar
Advancing Global Health through Development and Clinical Trials Partnerships: A Randomized, Placebo-Controlled, Double-Blind Assessment of Safety, Tolerability, and Immunogenicity of PfSPZ Vaccine for Malaria in Healthy Equatoguinean Men
A. Olotu, Vicente Urbano, Ali Hamad, Marten Eka +31 more
2017American Journal of Tropical Medicine and Hygiene68 citations Open access
Semantic Scholar
Increase of dose associated with decrease in protection against controlled human malaria infection by PfSPZ Vaccine in Tanzanian adults.
Said Jongo, L. W. Preston Church, A. Mtoro, Tobias Schindler +28 more
2019Clinical Infectious Diseases61 citations Open access
Semantic Scholar
A consultation on the optimization of controlled human malaria infection by mosquito bite for evaluation of candidate malaria vaccines.
M. Laurens, C. Duncan, J. Epstein, A. Hill +9 more
2012Vaccine61 citations
Semantic Scholar
Sterile Immunity to Malaria after DNA Prime/Adenovirus Boost Immunization Is Associated with Effector Memory CD8+T Cells Targeting AMA1 Class I Epitopes
M. Sedegah, M. Hollingdale, Fouzia Farooq, Harini Ganeshan +16 more
2014PLoS ONE58 citations Open access
Semantic Scholar
PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial with controlled human malaria infection
S. Murphy, G. Deye, B. K. Sim, Shirley Galbiati +10 more
2021PLoS Pathogens55 citations Open access
Semantic Scholar
Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria
Wathsala Wijayalath, Sai Majji, E. Villasante, T. Brumeanu +2 more
2014Malaria Journal52 citations Open access
Semantic Scholar
Heterologous protection against malaria by a simple chemoattenuated PfSPZ vaccine regimen in a randomized trial
Zita Sulyok, Rolf Fendel, Bianca V. A. Eder, Freia-Raphaella Lorenz +23 more
2021Nature Communications51 citations Open access
Semantic Scholar
A Glycolipid Adjuvant, 7DW8-5, Enhances CD8+ T Cell Responses Induced by an Adenovirus-Vectored Malaria Vaccine in Non-Human Primates
Neal N. Padte, Mar Boente-Carrera, Chasity D. Andrews, J. McManus +13 more
2013PLoS ONE50 citations Open access
Semantic Scholar
Beyond Blood Smears: Qualification of Plasmodium 18S rRNA as a Biomarker for Controlled Human Malaria Infections
A. Seilie, M. Chang, Amelia E. Hanron, Zachary P. Billman +34 more
2019American Journal of Tropical Medicine and Hygiene48 citations Open access
Semantic Scholar
Corrigendum: Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1
A. Ishizuka, K. Lyke, A. Dezure, Andrea A. Berry +52 more
2016Nature Medicine48 citations Open access
Semantic Scholar
Three dose regimen of PfSPZ Vaccine protects adult Malians against Plasmodium falciparum through an intense transmission season: a randomised, controlled phase I trial.
M. Sissoko, S. Healy, A. Katile, I. Zaidi +29 more
2021Lancet. Infectious Diseases (Print)47 citations Open access
Semantic Scholar
Protective Efficacy of Plasmodium vivax Radiation-Attenuated Sporozoites in Colombian Volunteers: A Randomized Controlled Trial
M. Arévalo-Herrera, J. Vásquez-Jiménez, M. Lopez-Perez, Andres F. Vallejo +9 more
2016PLoS Neglected Tropical Diseases47 citations Open access
Semantic Scholar
Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falciparum DNA vaccine combined with escalating dose human GM-CSF DNA
T. Richie, Y. Charoenvit, Ruo-Bing Wang, J. Epstein +31 more
2012Human Vaccines & Immunotherapeutics46 citations Open access
Semantic Scholar
Sporozoite immunization: innovative translational science to support the fight against malaria
T. Richie, L. W. Preston Church, T. Murshedkar, P. Billingsley +42 more
2023Expert Review of Vaccines45 citations Open access
Semantic Scholar
A PfSPZ vaccine immunization regimen equally protective against homologous and heterologous controlled human malaria infection
B. Mordmüller, Zita Sulyok, M. Sulyok, Z. Molnár +22 more
2022npj Vaccines43 citations Open access
Semantic Scholar
Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge
Scott G. Hansen, Jennie L Womack, Isabel G. Scholz, A. Renner +16 more
2019PLoS ONE41 citations Open access
Semantic Scholar
Discovery of Novel Plasmodium falciparum Pre-Erythrocytic Antigens for Vaccine Development
J. Aguiar, Jessica S. Bolton, Joyce Wanga, J. Sacci +13 more
2015PLoS ONE41 citations Open access
Semantic Scholar
Human adenovirus 5-vectored Plasmodium falciparum NMRC-M3V-Ad-PfCA vaccine encoding CSP and AMA1 is safe, well-tolerated and immunogenic but does not protect against controlled human malaria infection
C. Tamminga, M. Sedegah, S. Maiolatesi, C. Fedders +29 more
2013Human Vaccines & Immunotherapeutics41 citations Open access
Semantic Scholar
The whole parasite, pre-erythrocytic stage approach to malaria vaccine development: a review
J. Epstein, T. Richie
2013Current Opinion in Infectious Diseases39 citations
Semantic Scholar
Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP)
M. Sedegah, Yohan Kim, Harini Ganeshan, Jun Huang +14 more
2013Malaria Journal38 citations Open access
Semantic Scholar
World Malaria Report 2010: documenting progress towards malaria eradication
I. Chuang, T. Richie
201237 citations Open access
Semantic Scholar
Towards an optimized inhibition of liver stage development assay (ILSDA) for Plasmodium falciparum
Xiaoyan Zou, Brent L. House, M. Zyzak, T. Richie +1 more
2013Malaria Journal36 citations Open access
Semantic Scholar
A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria
S. Sirima, A. Ouédraogo, A. Tiono, J. Kaboré +24 more
2022Science Translational Medicine33 citations
Semantic Scholar
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria
D. Odera, J. Tuju, K. Mwai, I. Nkumama +66 more
2023Science Translational Medicine30 citations
Semantic Scholar
Human challenge trials in vaccine development, Rockville, MD, USA, September 28-30, 2017.
M. Baay, T. Richie, P. Neels, Marco Cavaleri +16 more
2019Biologicals (Print)30 citations
Semantic Scholar
Malaria vaccine trials in pregnant women: An imperative without precedent
S. Healy, M. Fried, T. Richie, K. Bok +12 more
2019Vaccine30 citations Open access
Semantic Scholar
PfSPZ-CVac malaria vaccine demonstrates safety among malaria-experienced adults: A randomized, controlled phase 1 trial
D. Coulibaly, A. Koné, K. Traore, Amadou Niangaly +20 more
2022EClinicalMedicine28 citations Open access
Semantic Scholar
Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity
Bradley W. Hickey, J. Lumsden, S. Reyes, M. Sedegah +22 more
2016Malaria Journal27 citations Open access
Semantic Scholar
Multi-Dose Priming Regimens of PfSPZ Vaccine: Safety and Efficacy against Controlled Human Malaria Infection in Equatoguinean Adults
Said Jongo, L. W. Preston Church, Vicente Urbano Nsue Ndong Nchama, Ali Hamad +52 more
2022American Journal of Tropical Medicine and Hygiene26 citations Open access
Semantic Scholar
Dose dependent infectivity of aseptic, purified, cryopreserved Plasmodium falciparum 7G8 sporozoites in malaria-naive adults.
M. Laurens, Andrea A. Berry, Mark A. Travassos, Kathy Strauss +16 more
2019Journal of Infectious Diseases26 citations Open access
Semantic Scholar
Controlled human malaria infection (CHMI) outcomes in Kenyan adults is associated with prior history of malaria exposure and anti-schizont antibody response
M. Kapulu, D. Kimani, P. Njuguna, M. Hamaluba +38 more
2022BMC Infectious Diseases25 citations Open access
Semantic Scholar
Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria
F. Musasia, I. Nkumama, R. Frank, Victor Kipkemboi +45 more
2022Nature Communications23 citations Open access
Semantic Scholar
IMRAS—A clinical trial of mosquito-bite immunization with live, radiation-attenuated P. falciparum sporozoites: Impact of immunization parameters on protective efficacy and generation of a repository of immunologic reagents
Bradley W. Hickey, Nimfa Teneza-mora, J. Lumsden, S. Reyes +30 more
2020PLoS ONE23 citations Open access
Semantic Scholar
Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection of low-density Plasmodium falciparum infections during a controlled human malaria infection study in Equatorial Guinea
Maxmillian Mpina, Thomas C Stabler, Tobias Schindler, J. Raso +27 more
2021Malaria Journal20 citations Open access
Semantic Scholar
Multidose Priming and Delayed Boosting Improve PfSPZ Vaccine Efficacy against Heterologous P. falciparum Controlled Human Malaria Infection.
K. Lyke, Alexandra Singer, Andrea A. Berry, S. Reyes +24 more
2020Clinical Infectious Diseases20 citations
Semantic Scholar
Ex vivo tetramer staining and cell surface phenotyping for early activation markers CD38 and HLA-DR to enumerate and characterize malaria antigen-specific CD8+ T-cells induced in human volunteers immunized with a Plasmodium falciparum adenovirus-vectored malaria vaccine expressing AMA1
R. Schwenk, Glenna Banania, J. Epstein, Yohan Kim +10 more
2013Malaria Journal19 citations Open access
Semantic Scholar
A three-antigen Plasmodium falciparum DNA prime—Adenovirus boost malaria vaccine regimen is superior to a two-antigen regimen and protects against controlled human malaria infection in healthy malaria-naïve adults
M. J. Sklar, S. Maiolatesi, N. Patterson, M. Sedegah +40 more
2021PLoS ONE18 citations Open access
Semantic Scholar
Immune Signature Against Plasmodium falciparum Antigens Predicts Clinical Immunity in Distinct Malaria Endemic Communities
C. Proietti, L. Krause, A. Trieu, D. Dodoo +7 more
2019Molecular & Cellular Proteomics18 citations Open access
Semantic Scholar

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