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K. McDonagh · SciRah

Researcher profile · Semantic Scholar

K. McDonagh

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K. McDonagh — researcher profile on SciRah

h-index: 25
Works: 71
Citations: 3,782

Most-cited papers

Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer
R. Donahue, S. Kessler, D. Bodine, K. McDonagh +6 more
1992Journal of Experimental Medicine551 citations Open access
Semantic Scholar
MT1-MMP–dependent neovessel formation within the confines of the three-dimensional extracellular matrix
T. Chun, F. Sabeh, I. Ota, H. Murphy +5 more
2004Journal of Cell Biology355 citations Open access
Semantic Scholar
Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: a clinical trial.
A. Collins, H. Pearson, P. Giardina, K. McDonagh +2 more
1995Blood268 citations Open access
Semantic Scholar
High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study.
R. Nash, P. Mcsweeney, L. Crofford, M. Abidi +18 more
2007Blood252 citations Open access
Semantic Scholar
Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells.
P. Ney, B. Sorrentino, K. McDonagh, A. Nienhuis
1990Genes & Development246 citations Open access
Semantic Scholar
Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis.
Y. Morita, Jian-Min Yang, Raj K. Gupta, K. Shimizu +5 more
2001Journal of Clinical Investigation218 citations Open access
Semantic Scholar
An open-label, single-arm, phase 2 study of single-agent carfilzomib in patients with relapsed and/or refractory multiple myeloma who have been previously treated with bortezomib
R. Vij, David S. Siegel, S. Jagannath, A. Jakubowiak +9 more
2012British Journal of Haematology182 citations Open access
Semantic Scholar
Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.
D. Bodine, K. McDonagh, S. Brandt, P. Ney +3 more
1990Proceedings of the National Academy of Sciences of the United States of America178 citations Open access
Semantic Scholar
High-dose immunosuppressive therapy for severe systemic sclerosis: initial outcomes.
P. Mcsweeney, R. Nash, K. Sullivan, J. Storek +15 more
2002Blood172 citations Open access
Semantic Scholar
Thrombosis in patients with connective tissue diseases treated with specific cyclooxygenase 2 inhibitors. A report of four cases.
L. Crofford, James C. Oates, W. Mccune, Samar Gupta +5 more
2000Arthritis & Rheumatism160 citations Open access
Semantic Scholar
Survival and retrovirus infection of murine hematopoietic stem cells in vitro: effects of 5-FU and method of infection.
D. Bodine, K. McDonagh, N. E. Seidel, A. Nienhuis
1991Experimental Hematology147 citations
Semantic Scholar
Cell Surface Expression of Epidermal Growth Factor Receptor and Her-2 with Nuclear Expression of Her-4 in Primary Osteosarcoma
D. Hughes, Dafydd Thomas, T. Giordano, L. Baker +1 more
2004Cancer Research142 citations Open access
Semantic Scholar
Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder after high-dose immunosuppressive therapy and autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases.
R. Nash, R. Dansey, J. Storek, G. Georges +13 more
2003Biology of Blood and Marrow Transplantation88 citations Open access
Semantic Scholar
Phase I study of MLN8237—investigational Aurora A kinase inhibitor—in relapsed/refractory multiple myeloma, Non-Hodgkin lymphoma and chronic lymphocytic leukemia
K. Kelly, T. Shea, A. Goy, J. Berdeja +9 more
2013Investigational new drugs79 citations Open access
Semantic Scholar
Retroviral Mediated Transfer of the Human Multidrug Resistance Gene (MDR-1) into Hematopoietic Stem Cells During Autologous Transplantation after Intensive Chemotherapy for Metastatic Breast Cancer. National Institutes of Health, Bethesda, Maryland
J. O'Shaughnessy, K. Cowan, A. Nienhuis, K. McDonagh +13 more
199479 citations
Semantic Scholar
Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability.
T. M. Williams, Melissa E. Williams, R. Kuick, David E. Misek +3 more
2005Developmental Biology68 citations Open access
Semantic Scholar
Essential erbB family phosphorylation in osteosarcoma as a target for CI‐1033 inhibition
D. Hughes, Dafydd Thomas, T. Giordano, K. McDonagh +1 more
200645 citations Open access
Semantic Scholar
Hydroxyurea-induced HbF production in anemic primates: augmentation by erythropoietin, hematopoietic growth factors, and sodium butyrate.
K. McDonagh, G. Dover, R. Donahue, David G. Nathan +3 more
1992Experimental Hematology40 citations
Semantic Scholar
The upstream region of the human gamma-globin gene promoter. Identification and functional analysis of nuclear protein binding sites.
K. McDonagh, Henry J. Lin, C. Lowrey, D. Bodine +1 more
1991Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Phase I Study of the Investigational Aurora A Kinase Inhibitor Alisertib plus Rituximab or Rituximab/Vincristine in Relapsed/Refractory Aggressive B-cell Lymphoma
K. Kelly, Jonathan W. Friedberg, Steven I. Park, K. McDonagh +21 more
2018Clinical Cancer Research35 citations Open access
Semantic Scholar
Genetically engineered T cells expressing a HER2-specific chimeric receptor mediate antigen-specific tumor regression
S. Li, J. Yang, F. Urban, J. Macgregor +4 more
2008Cancer Gene Therapy35 citations Open access
Semantic Scholar
Ex vivo culture with interleukin (IL)-12 improves CD8(+) T-cell adoptive immunotherapy for murine leukemia independent of IL-18 or IFN-gamma but requires perforin.
J. Macgregor, Qiao Li, A. Chang, T. Braun +2 more
2006Cancer Research34 citations Open access
Semantic Scholar
Structure and function of the enhancer 3' to the human A gamma globin gene.
M. Purucker, D. Bodine, Henry J. Lin, K. McDonagh +1 more
1990Nucleic Acids Research34 citations Open access
Semantic Scholar
Gene transfer into hematopoietic stem cells
A. Nienhuis, K. McDonagh, D. Bodine
1991Cancer32 citations Open access
Semantic Scholar
Donor Cell Cycling, Trafficking, and Accumulation during Adoptive Immunotherapy for Murine Lung Metastases
Joseph J. Skitzki, R. Craig, R. Okuyama, R. Knibbs +3 more
2004Cancer Research29 citations Open access
Semantic Scholar
Gene Transfer into Hematopoietic Cells: Implications for Cancer Therapy
Cynthia E. Dunbar, D. Bodine, B. Sorrentino, R. Donahue +8 more
199423 citations
Semantic Scholar
Upstream sequences within the terminal hairpin positively regulate the P6 promoter of B19 parvovirus.
Johnson M. Liu, S. Green, Yu-Shuo Hao, K. McDonagh +2 more
1991Virology22 citations
Semantic Scholar
Highly efficient genetic transduction of primary human synoviocytes with concentrated retroviral supernatant
Jian-Min Yang, Michael S. Friedman, Hui-Min Bian, L. Crofford +2 more
2002Arthritis Research & Therapy18 citations Open access
Semantic Scholar
Final Results From the Bortezomib-naïve Group of PX-171-004, a Phase 2 Study of Single-Agent Carfilzomib in Patients with Relapsed and/or Refractory MM
R. Vij, J. Kaufman, A. Jakubowiak, Michael L. Wang +16 more
201117 citations
Semantic Scholar
Cytokine production by dendritic cells genetically engineered to express IL‐4: induction of Th2 responses and differential regulation of IL‐12 and IL‐23 synthesis
Y. Morita, Raj K. Gupta, Kelly M. Seidl, K. McDonagh +1 more
2005Journal of Gene Medicine17 citations Open access
Semantic Scholar
Adenovirus binding to cultured synoviocytes triggers signaling through MAPK pathways and induces expression of cyclooxygenase‐2
L. Crofford, K. McDonagh, Su-Tang Guo, H. Mehta +3 more
2005Journal of Gene Medicine16 citations Open access
Semantic Scholar
Gene Therapy in Tissue-Engineered Blood Vessels
R. Fields, Amy K. Solan, K. McDonagh, L. Niklason +1 more
2003Tissue engineering16 citations Open access
Semantic Scholar
Antigen‐specific tumor vaccine efficacy in vivo against prostate cancer with low class I MHC requires competent class II MHC
Yilin C. Neeley, K. McDonagh, W. Overwijk, N. Restifo +1 more
2002The Prostate15 citations Open access
Semantic Scholar
Phase I Study of the Novel Surivin and cdc2/CDK1 Inhibitor Terameprocol in Patients with Advanced Leukemias.
R. Tibes, K. McDonagh, L. Lekakis, N. Frazer +8 more
200913 citations
Semantic Scholar
Retrovirus mediated gene transfer of the self antigen MBP into the bone marrow of mice alters resistance to experimental autoimmune encephalomyelitis.
T. R. Peters, D. Bodine, K. McDonagh, A. Lovett-Racke +4 more
2000Journal of Neuroimmunology12 citations
Semantic Scholar
Combination Treatment of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib and Carfilzomib in Patients with Relapsed or Relapsed and Refractory Multiple Myeloma: Initial Results from a Multicenter Phase 1/2b Study
A. Chari, S. Chhabra, S. Usmani, Sarah M. Larson +13 more
201511 citations Open access
Semantic Scholar
Erratum: Essential erbB family phosphorylation in osteosarcoma as a target for CI‐1033 inhibition
D. Hughes, Dafydd Thomas, T. Giordano, K. McDonagh +1 more
2013Pediatric Blood & Cancer11 citations
Semantic Scholar
Fate and function of anti-CD3/CD28-activated T cells following adoptive transfer: IL-2 promotes development of anti-tumor memory T cells in vivo.
D. Hughes, D. Baskar, F. Urban, Michael S. Friedman +2 more
2005Cytotherapy11 citations
Semantic Scholar
Phase I Study of An Investigational Aurora A Kinase Inhibitor MLN8237 In Patients with Advanced Hematologic Malignancies.
S. Padmanabhan, T. Shea, J. Vose, C. Reeder +8 more
201010 citations
Semantic Scholar
Development of a High‐Titer Retrovirus Producer Cell Line and Strategies for Retrovirus‐mediated Gene Transfer into Rhesus Monkey Hematopoietic Stem Cells
D. Bodine, K. McDonagh, N. E. Seidel, A. Nienhuis
1990Annals of the New York Academy of Sciences10 citations
Semantic Scholar
Manipulation of HbF production with hematopoietic growth factors.
K. McDonagh, George J. Dover, R. Donahue, David G. Nathan +1 more
1989Progress in clinical and biological research7 citations
Semantic Scholar
Phase 1 Study Of Investigational Agent MLN8237 (Alisertib) + Rituximab ± Vincristine In Patients (Pts) With Relapsed/Refractory (Rel/Ref) Aggressive B-Cell Lymphomas
D. Persky, D. Mahadevan, T. Miller, S. Puvvada +12 more
20136 citations
Semantic Scholar
Identifying grant funding: mentored career development and transition awards.
K. McDonagh
2008Hematology. American Society of Hematology. Education Program6 citations Open access
Semantic Scholar
Identification of the molecular genetic defect of patients with methemoglobin M Kankakee (M-Iwate), α87 (F8) His → Tyr: Evidence for an electrostatic model of αM hemoglobin assembly
A. Ameri, V. Fairbanks, G. Yanik, F. Mahdi +4 more
19995 citations
Semantic Scholar
Results From a Phase 1 Multicenter Trial of Alisertib (MLN8237)–An Investigational Aurora A Kinase Inhibitor–in Patients with Advanced Hematologic Malignancies
K. Kelly, S. Padmanabhan, A. Goy, J. Berdeja +7 more
20114 citations
Semantic Scholar
Influence of Cytogenetics in Patients with Relapsed and Refractory Multiple Myeloma (MM) Treated with Carfilzomib (CFZ).
A. Jakubowiak, Lu-Hua Wang, R. Orlowski, S. Jagannath +8 more
20094 citations
Semantic Scholar
Inhibition of the Proteasome in Bone Marrow-Derived CD138+ Tumor Cells Following Carfilzomib Administration in Relapsed or Refractory Myeloma Patients.
S. Trudel, Susan Lee, C. Kirk, N. Gabrail +10 more
20093 citations
Semantic Scholar
High-Dose Immunosuppressive Therapy (HDIT) for Severe Systemic Sclerosis (SSc): Long-Term Survivors Show Continued Improvement of Function and Skin with Stability in the Lungs.
P. Mcsweeney, D. Furst, L. Crofford, K. McDonagh +13 more
20043 citations
Semantic Scholar
Applications of Gene Transfer in the Adoptive Immunotherapy of Cancer
K. McDonagh, A. Chang
20023 citations
Semantic Scholar
Identification of the molecular genetic defect of patients with methemoglobin M-Kankakee (M-Iwate), alpha87 (F8) His --> Tyr: evidence for an electrostatic model of alphaM hemoglobin assembly.
A. Ameri, V. Fairbanks, G. Yanik, F. Mahdi +4 more
1999Blood3 citations
Semantic Scholar

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