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H. Mehta · SciRah

Researcher profile · Semantic Scholar

H. Mehta

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H. Mehta — researcher profile on SciRah

h-index: 25
Works: 68
Citations: 3,079

Most-cited papers

The Mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
Chang-Han D. Lee, Jennifer Zeng, B. Drew, T. Sallam +7 more
2015Cell Metabolism665 citations Open access
Semantic Scholar
Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers
L. Cobb, Chang-Han D. Lee, Jialin Xiao, K. Yen +10 more
2016Aging262 citations Open access
Semantic Scholar
The emerging role of the mitochondrial-derived peptide humanin in stress resistance
K. Yen, Chang-Han D. Lee, H. Mehta, P. Cohen
2013Journal of Molecular Endocrinology193 citations Open access
Semantic Scholar
The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction
P. Sreekumar, K. Ishikawa, C. Spee, H. Mehta +5 more
2016Investigative Ophthalmology and Visual Science167 citations Open access
Semantic Scholar
Aberrant Phenotype and Function of Myeloid Dendritic Cells in Systemic Lupus Erythematosus1
D. Ding, H. Mehta, W. Mccune, M. Kaplan
2006Journal of Immunology154 citations Open access
Semantic Scholar
Mitochondrial peptides modulate mitochondrial function during cellular senescence
Su-Jeong Kim, H. Mehta, J. Wan, Chisaka Kuehnemann +4 more
2018Aging131 citations Open access
Semantic Scholar
Pomegranate extract induces apoptosis in human prostate cancer cells by modulation of the IGF-IGFBP axis
Satomi Koyama, L. Cobb, H. Mehta, N. Seeram +3 more
2008Growth Hormone & IGF Research116 citations Open access
Semantic Scholar
The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan
K. Yen, H. Mehta, Su-Jeong Kim, Y. Lue +18 more
2020Aging97 citations Open access
Semantic Scholar
Effects of air pollution on mitochondrial function, mitochondrial DNA methylation, and mitochondrial peptide expression
Carrie V. Breton, Ashley Y. Song, Jialin Xiao, Su-Jeong Kim +9 more
2019Mitochondrion (Amsterdam. Print)96 citations Open access
Semantic Scholar
IGFBP-3 is a Metastasis Suppression Gene in Prostate Cancer
H. Mehta, Qing-Lei Gao, C. Galet, Vladislava Paharkova +7 more
2011Cancer Research95 citations Open access
Semantic Scholar
The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus
Su-Jeong Kim, Noel Guerrero, Gabriella Wassef, Jialin Xiao +3 more
2016OncoTarget92 citations Open access
Semantic Scholar
Humanin Prevents Age-Related Cognitive Decline in Mice and is Associated with Improved Cognitive Age in Humans
K. Yen, J. Wan, H. Mehta, Brendan Miller +15 more
2018Scientific Reports85 citations Open access
Semantic Scholar
Host mitochondrial transcriptome response to SARS-CoV-2 in multiple cell models and clinical samples
Brendan Miller, Ana R. Silverstein, Melanie K. Flores, Kevin Cao +5 more
2021Scientific Reports71 citations Open access
Semantic Scholar
Peptides derived from small mitochondrial open reading frames: Genomic, biological, and therapeutic implications
Brendan Miller, Su-Jeong Kim, H. Kumagai, H. Mehta +4 more
2020Experimental Cell Research68 citations Open access
Semantic Scholar
MOTS-c reduces myostatin and muscle atrophy signaling.
H. Kumagai, Ana R. Coelho, J. Wan, H. Mehta +8 more
2021American Journal of Physiology. Endocrinology and Metabolism61 citations Open access
Semantic Scholar
Opposing roles of insulin-like growth factor binding protein 3 and humanin in the regulation of testicular germ cell apoptosis.
Y. Lue, R. Swerdloff, Qing-Hai Liu, H. Mehta +7 more
2010Endocrinology59 citations Open access
Semantic Scholar
Pharmacokinetics and tissue distribution of humanin and its analogues in male rodents.
Yung-Ping Chin, Jyotsna Keni, J. Wan, H. Mehta +7 more
2013Endocrinology57 citations Open access
Semantic Scholar
Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation.
P. M. Yamada, H. Mehta, David Hwang, K. Roos +2 more
2010Endocrinology57 citations Open access
Semantic Scholar
Targeted deletion of hepatic Igf1 in TRAMP mice leads to dramatic alterations in the circulating insulin-like growth factor axis but does not reduce tumor progression.
M. Anzo, L. Cobb, David Hwang, H. Mehta +4 more
2008Cancer Research56 citations Open access
Semantic Scholar
The mitochondrial‐derived peptide MOTS‐c is a regulator of plasma metabolites and enhances insulin sensitivity
Su-Jeong Kim, Brendan Miller, H. Mehta, Jialin Xiao +4 more
2019Physiological Reports53 citations Open access
Semantic Scholar
Chronic treatment with the mitochondrial peptide humanin prevents age-related myocardial fibrosis in mice.
Q. Qin, H. Mehta, K. Yen, Gerardo Navarrete +7 more
2018American Journal of Physiology. Heart and Circulatory Physiology52 citations Open access
Semantic Scholar
Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE
Brendan Miller, Su-Jeong Kim, H. Mehta, Kevin Cao +24 more
2022Molecular Psychiatry47 citations Open access
Semantic Scholar
Metabolomic profile of diet-induced obesity mice in response to humanin and small humanin-like peptide 2 treatment
H. Mehta, Jialin Xiao, R. Ramirez, Brendan Miller +3 more
2019Metabolomics45 citations Open access
Semantic Scholar
A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c
H. Zempo, Su-Jeong Kim, N. Fuku, Yuichiro Nishida +25 more
2019bioRxiv45 citations Open access
Semantic Scholar
Humanin is a novel regulator of Hedgehog signaling and prevents glucocorticoid‐induced bone growth impairment
F. Zaman, Yunhan Zhao, Bettina Celvin, H. Mehta +6 more
2019The FASEB Journal40 citations Open access
Semantic Scholar
Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension
Su-Jeong Kim, Anjali Devgan, Brendan Miller, S. Lee +7 more
2021Biochimica et Biophysica Acta - General Subjects23 citations Open access
Semantic Scholar
Bladder cancer cells shift rapidly and spontaneously to cisplatin-resistant oxidative phosphorylation that is trackable in real time
Tong Xu, J. Junge, Alireza Delfarah, Yi-Tsung Lu +10 more
2022Scientific Reports20 citations Open access
Semantic Scholar
Comparing the Utility of Mitochondrial and Nuclear DNA to Adjust for Genetic Ancestry in Association Studies
Brendan Miller, T. Arpawong, Henry Jiao, Su-Jeong Kim +5 more
2019Cells20 citations Open access
Semantic Scholar
Mitochondrial-derived microprotein MOTS-c attenuates immobilization-induced skeletal muscle atrophy by suppressing lipid infiltration.
H. Kumagai, Su-Jeong Kim, Brendan Miller, Toshiharu Natsume +8 more
2024American Journal of Physiology. Endocrinology and Metabolism19 citations Open access
Semantic Scholar
Correction: Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE
Brendan Miller, Su-Jeong Kim, H. Mehta, Kevin Cao +24 more
2023Molecular Psychiatry19 citations Open access
Semantic Scholar
Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4‐induced brain pathology
Brendan Miller, Su-Jeong Kim, Kevin Cao, H. Mehta +13 more
2024Aging Cell18 citations Open access
Semantic Scholar
Enhancing the apoptotic potential of insulin-like growth factor-binding protein-3 in prostate cancer by modulation of CK2 phosphorylation.
L. Cobb, H. Mehta, P. Cohen
2009Molecular Endocrinology18 citations Open access
Semantic Scholar
Adenovirus binding to cultured synoviocytes triggers signaling through MAPK pathways and induces expression of cyclooxygenase‐2
L. Crofford, K. McDonagh, Su-Tang Guo, H. Mehta +3 more
2005Journal of Gene Medicine16 citations Open access
Semantic Scholar
Global IGFBP-1 deletion does not affect prostate cancer development in a c-Myc transgenic mouse model
A. Gray, W. Aronson, R. Barnard, H. Mehta +4 more
2011Journal of Endocrinology15 citations Open access
Semantic Scholar
MOTS-c modulates skeletal muscle function by directly binding and activating CK2
H. Kumagai, Su-Jeong Kim, Brendan Miller, H. Zempo +31 more
2024iScience14 citations Open access
Semantic Scholar
A Mitochondrial Genome-Wide Association Study of Cataract in a Latino Population
Brendan Miller, M. Torres, Xue-Juan Jiang, R. Mckean-Cowdin +6 more
2020Translational Vision Science & Technology12 citations Open access
Semantic Scholar
SARS-CoV-2 induces a unique mitochondrial transcriptome signature
Brendan Miller, Ana R. Silverstein, Melanie K. Flores, Wang Xiang +6 more
20208 citations Open access
Semantic Scholar
Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging
Naibedya Dutta, Joe A. Gerke, Sofia F. Odron, Joseph D Morris +20 more
2024GeroScience6 citations Open access
Semantic Scholar
MITOCHONDRIAL-DERIVED PEPTIDE, SHLP2, A NOVEL PROTECTIVE FACTOR IN PARKINSON’S DISEASE
S. J. Kim, Anjali Devgan, H. Mehta, P. Cohen
2019Innovation in aging4 citations Open access
Semantic Scholar
Form and function of actin impacts actin health and aging
Maxim Averbukh, Hunter T. Nelson, Tiffany Wang, Caitlin M. Lange +34 more
2026iScience2 citations Open access
Semantic Scholar
Abstract P461: The Association of NOV/CCN3 With Obstructive Sleep Apnea in Severe Morbid Obesity: Preliminary Evidence of a Novel Biomarker in OSA
J. Weingarten, L. Bellner, Stephen J. Peterson, M. Zaw +3 more
20172 citations
Semantic Scholar
Mitochondrial DNA copy number assessment is a potent predictor for prostate cancer in White but not Black Individuals
Melanie K. Flores, Jessica L. Janes, Mirajul Islam, J. Wan +11 more
2025Cancer Prevention Research1 citations
Semantic Scholar
Form and function of actin impacts actin health and aging
Maxim Averbukh, H. Nelson, Tiffany Wang, Caitlin M. Lange +30 more
2025bioRxiv1 citations
Semantic Scholar
Alterations in gut microbiome in age- and diet-induced colorectal cancer (CRC) progression in a preclinical model.
P. Mittal, S. Soni, Keehoon Lee, G. Smbatyan +14 more
2025Journal of Clinical Oncology1 citations
Semantic Scholar
Age-diet interactions significantly influence intratumoral gene expression, gut microbiome signature and tumor microenvironment in colorectal cancer
S. Soni, P. Mittal, J. H. Lo, Yan Yang +16 more
2025Neoplasia1 citations Open access
Semantic Scholar
344-OR: The MOTS-c/CK2 Pathway Is a Novel Molecular Target for Type 2 Diabetes in East Asians
H. Kumagai, Su Jeong Kim, Brendan Miller, Shin Hyung Lee +17 more
2024Diabetes1 citations
Semantic Scholar
Abstract 4234: Effects of age-diet interactions on colorectal cancer (CRC) progression in mice
J. H. Lo, S. Soni, Yan Yang, G. Smbatyan +11 more
2023Cancer Research1 citations
Semantic Scholar
Casein kinase 2 is a direct binding partner and a functional target of the exercise-mimetic microprotein MOTS-c
H. Kumagai, Su-Jeong Kim, Brendan Miller, Toshiharu Natsume +7 more
2023Physiology1 citations
Semantic Scholar
Bladder cancer cells shift rapidly and spontaneously to cisplatin-resistant oxidative phosphorylation that is trackable in real time
Tong Xu, J. Junge, Alireza Delfarah, Yi-Tsung Lu +10 more
2022Scientific Reports1 citations Open access
Semantic Scholar
Mito-Omics and immune function: Applying novel mitochondrial omic techniques to the context of the aging immune system
Ana R. Silverstein, Melanie K. Flores, Brendan Miller, Su-Jeong Kim +3 more
2020Translational Medicine of Aging1 citations Open access
Semantic Scholar

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