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Adriana Carino · SciRah

Researcher profile · Semantic Scholar

Adriana Carino

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Adriana Carino — researcher profile on SciRah

h-index: 29
Works: 83
Citations: 2,673

Most-cited papers

The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis
M. Biagioli, Adriana Carino, S. Cipriani, D. Francisci +5 more
2017Journal of Immunology289 citations
Semantic Scholar
Bile acids and their receptors in metabolic disorders.
S. Fiorucci, E. Distrutti, Adriana Carino, A. Zampella +1 more
2021Progress in lipid research237 citations
Semantic Scholar
Bile Acid Signaling in Inflammatory Bowel Diseases
S. Fiorucci, Adriana Carino, Monia Baldoni, L. Santucci +4 more
2020Digestive Diseases and Sciences208 citations Open access
Semantic Scholar
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis
Adriana Carino, S. Cipriani, S. Marchianò, M. Biagioli +5 more
2017Scientific Reports128 citations Open access
Semantic Scholar
The Bile Acid Sensor FXR Is Required for Immune-Regulatory Activities of TLR-9 in Intestinal Inflammation
B. Renga, A. Mencarelli, S. Cipriani, Claudio D'Amore +6 more
2013PLoS ONE104 citations Open access
Semantic Scholar
Bile Acids Activated Receptors in Inflammatory Bowel Disease
M. Biagioli, S. Marchianò, Adriana Carino, C. Di Giorgio +3 more
2021Cells91 citations Open access
Semantic Scholar
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain
Adriana Carino, Federica Moraca, Bianca Fiorillo, S. Marchianò +9 more
2020Frontiers in Chemistry91 citations Open access
Semantic Scholar
Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands.
C. Festa, B. Renga, Claudio D'Amore, V. Sepe +7 more
2014Journal of Medicinal Chemistry82 citations Open access
Semantic Scholar
Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1
B. Renga, S. Cipriani, Adriana Carino, Michele Simonetti +2 more
2015PLoS ONE67 citations Open access
Semantic Scholar
GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis
M. Biagioli, Adriana Carino, C. Fiorucci, S. Marchianò +8 more
2019Cellular and Molecular Gastroenterology and Hepatology64 citations Open access
Semantic Scholar
The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines
Adriana Carino, L. Graziosi, Claudio D'Amore, S. Cipriani +8 more
2016OncoTarget64 citations Open access
Semantic Scholar
Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids.
B. Renga, M. Bucci, S. Cipriani, Adriana Carino +6 more
2015American Journal of Physiology. Heart and Circulatory Physiology58 citations
Semantic Scholar
Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity
M. Biagioli, L. Laghi, Adriana Carino, S. Cipriani +6 more
2017Frontiers in Pharmacology56 citations Open access
Semantic Scholar
Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling
S. Cipriani, B. Renga, Claudio D'Amore, Michele Simonetti +6 more
2015PLoS ONE55 citations Open access
Semantic Scholar
Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH.
Adriana Carino, M. Biagioli, S. Marchianò, C. Fiorucci +6 more
2019Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids54 citations
Semantic Scholar
Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice
Adriana Carino, S. Cipriani, S. Marchianò, M. Biagioli +4 more
2017Scientific Reports54 citations Open access
Semantic Scholar
Endocrine activities and adipogenic effects of bisphenol AF and its main metabolite.
D. G. Skledar, Adriana Carino, J. Trontelj, Johanna Troberg +7 more
2019Chemosphere50 citations Open access
Semantic Scholar
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis
Adriana Carino, S. Marchianò, M. Biagioli, M. Bucci +7 more
2018The FASEB Journal48 citations
Semantic Scholar
Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists
S. De Marino, Adriana Carino, Dario Masullo, C. Finamore +8 more
2017Scientific Reports45 citations Open access
Semantic Scholar
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis.
Adriana Carino, M. Biagioli, S. Marchianò, C. Fiorucci +10 more
2020Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids44 citations
Semantic Scholar
Signaling from Intestine to the Host: How Bile Acids Regulate Intestinal and Liver Immunity.
M. Biagioli, Adriana Carino
2019Handbook of Experimental Pharmacology44 citations
Semantic Scholar
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists
V. Sepe, C. Festa, B. Renga, Adriana Carino +7 more
2016Scientific Reports44 citations Open access
Semantic Scholar
Disruption of TFG&bgr;‐SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand
Adriana Carino, M. Biagioli, S. Marchianò, P. Scarpelli +3 more
2018Pharmacological Research39 citations
Semantic Scholar
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity
M. Biagioli, Adriana Carino, C. Fiorucci, S. Marchianò +7 more
2020Journal of Immunology37 citations Open access
Semantic Scholar
Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury.
V. Sepe, S. Marchianò, C. Finamore, Giuliana Baronissi +11 more
2018ACS Medicinal Chemistry Letters35 citations Open access
Semantic Scholar
Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists.
C. Festa, C. Finamore, S. Marchianò, F. S. Di Leva +8 more
2019ACS Medicinal Chemistry Letters34 citations Open access
Semantic Scholar
Divergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic Properties
M. Biagioli, Daniela Capobianco, Adriana Carino, S. Marchianò +4 more
2019Nutrients33 citations Open access
Semantic Scholar
Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
Adriana Carino, S. Marchianò, M. Biagioli, C. Fiorucci +9 more
2019Nutrients32 citations Open access
Semantic Scholar
Solomonsterol A, a Marine Pregnane-X-Receptor Agonist, Attenuates Inflammation and Immune Dysfunction in a Mouse Model of Arthritis
A. Mencarelli, Claudio D'Amore, B. Renga, S. Cipriani +7 more
2013Marine Drugs30 citations Open access
Semantic Scholar
The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions
M. Biagioli, Adriana Carino, C. Fiorucci, Giannamaria Annunziato +12 more
2019Nutrients27 citations Open access
Semantic Scholar
Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential
Adriana Carino, L. Graziosi, S. Marchianò, M. Biagioli +6 more
2021bioRxiv25 citations Open access
Semantic Scholar
Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases
C. Festa, S. De Marino, Adriana Carino, V. Sepe +9 more
2017Frontiers in Pharmacology25 citations Open access
Semantic Scholar
HIV-1 infection is associated with changes in nuclear receptor transcriptome, pro-inflammatory and lipid profile of monocytes
B. Renga, D. Francisci, Claudio D'Amore, E. Schiaroli +3 more
2012BMC Infectious Diseases25 citations Open access
Semantic Scholar
Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction
M. Biagioli, S. Marchianò, Rosalinda Roselli, C. Di Giorgio +12 more
2021Biochemical Pharmacology24 citations Open access
Semantic Scholar
Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics
Bianca Fiorillo, S. Marchianò, Federica Moraca, V. Sepe +7 more
2021Journal of Chemical Information and Modeling23 citations Open access
Semantic Scholar
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy
Adriana Carino, S. Marchianò, M. Biagioli, P. Scarpelli +8 more
2020The FASEB Journal22 citations
Semantic Scholar
Hijacking SARS-Cov-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on receptor binding region
Adriana Carino, Federica Moraca, Bianca Fiorillo, S. Marchianò +9 more
2020bioRxiv22 citations Open access
Semantic Scholar
Serum Bile Acid Levels Before and After Sleeve Gastrectomy and Their Correlation with Obesity-Related Comorbidities
S. De Vuono, M. Ricci, Elisa Nulli Migliola, M. Monti +7 more
2019Obesity Surgery21 citations
Semantic Scholar
Genetic and Pharmacological Dissection of the Role of Spleen Tyrosine Kinase (Syk) in Intestinal Inflammation and Immune Dysfunction in Inflammatory Bowel Diseases.
M. Biagioli, A. Mencarelli, Adriana Carino, S. Cipriani +8 more
2017Inflammatory Bowel Diseases20 citations
Semantic Scholar
Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity.
V. Sepe, B. Renga, C. Festa, C. Finamore +6 more
2016Steroids20 citations
Semantic Scholar
Structural insights into Estrogen Related Receptor-β modulation: 4-methylenesterols from Theonella swinhoei sponge as the first example of marine natural antagonists.
S. Di Micco, B. Renga, Adriana Carino, M. D'Auria +4 more
2014Steroids20 citations
Semantic Scholar
FXR mediates a chromatin looping in the GR promoter thus promoting the resolution of colitis in rodents.
B. Renga, Claudio D'Amore, S. Cipriani, A. Mencarelli +5 more
2013Pharmacological Research20 citations
Semantic Scholar
New brominated flame retardants and their metabolites as activators of the pregnane X receptor.
Darja Gramec Skledar, T. Tomašič, Adriana Carino, E. Distrutti +2 more
2016Toxicology Letters18 citations
Semantic Scholar
Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands
C. Finamore, C. Festa, B. Renga, V. Sepe +8 more
2016Scientific Reports17 citations Open access
Semantic Scholar
Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1
F. S. Di Leva, C. Festa, Adriana Carino, S. De Marino +7 more
2019Scientific Reports15 citations Open access
Semantic Scholar
The HIV Matrix Protein p17 Promotes the Activation of Human Hepatic Stellate Cells through Interactions with CXCR2 and Syndecan-2
B. Renga, D. Francisci, E. Schiaroli, Adriana Carino +9 more
2014PLoS ONE15 citations Open access
Semantic Scholar
The MyoGravity project to study real microgravity effects on human muscle precursor cells and tissue
E. Di Filippo, Sara Chiappalupi, S. Falone, V. Dolo +11 more
2024npj Microgravity13 citations Open access
Semantic Scholar
The crosstalk between gut barrier impairment, mitochondrial dysfunction, and microbiota alterations in people living with HIV
Letizia Santinelli, Giacomo Rossi, G. Gioacchini, R. Verin +14 more
2022Journal of Medical Virology13 citations Open access
Semantic Scholar
Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation
M. Biagioli, Adriana Carino, C. Di Giorgio, S. Marchianò +4 more
2020Nutrients13 citations Open access
Semantic Scholar
Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis
S. Cipriani, Adriana Carino, Dario Masullo, A. Zampella +2 more
2017Scientific Reports13 citations Open access
Semantic Scholar

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S. Fiorucci×48
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S. Fiorucci — researcher profile on SciRah
A. Zampella×35
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A. Zampella — researcher profile on SciRah
S. Marchianò×32
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S. Marchianò — researcher profile on SciRah
E. Distrutti×30
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E. Distrutti — researcher profile on SciRah

×27

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M. Biagioli — researcher profile on SciRah

S. Cipriani×19

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S. Cipriani — researcher profile on SciRah

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M. Monti — researcher profile on SciRah

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B. Renga — researcher profile on SciRah

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V. Sepe — researcher profile on SciRah

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C. Fiorucci — researcher profile on SciRah

C. Finamore×10

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C. Di Giorgio×9

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C. Di Giorgio — researcher profile on SciRah