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S. Fiorucci · SciRah

Researcher profile · Semantic Scholar

S. Fiorucci

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S. Fiorucci — researcher profile on SciRah

h-index: 79
Works: 485
Citations: 24K

Most-cited papers

Bile acids and their receptors in metabolic disorders.
S. Fiorucci, E. Distrutti, Adriana Carino, A. Zampella +1 more
2021Progress in lipid research237 citations
Semantic Scholar
Bile Acid Signaling in Inflammatory Bowel Diseases
S. Fiorucci, Adriana Carino, Monia Baldoni, L. Santucci +4 more
2020Digestive Diseases and Sciences208 citations Open access
Semantic Scholar
The Pharmacology of Bile Acids and Their Receptors.
S. Fiorucci, E. Distrutti
2019Handbook of Experimental Pharmacology99 citations
Semantic Scholar
Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH)
S. Fiorucci, M. Biagioli, V. Sepe, A. Zampella +1 more
2020Expert Opinion on Investigational Drugs93 citations
Semantic Scholar
Bile Acids Activated Receptors in Inflammatory Bowel Disease
M. Biagioli, S. Marchianò, Adriana Carino, C. Di Giorgio +3 more
2021Cells91 citations Open access
Semantic Scholar
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain
Adriana Carino, Federica Moraca, Bianca Fiorillo, S. Marchianò +9 more
2020Frontiers in Chemistry91 citations Open access
Semantic Scholar
Immunology of bile acids regulated receptors.
S. Fiorucci, S. Marchianò, G. Urbani, C. Di Giorgio +3 more
2024Progress in lipid research79 citations
Semantic Scholar
Obeticholic Acid: An Update of Its Pharmacological Activities in Liver Disorders.
S. Fiorucci, C. Di Giorgio, E. Distrutti
2019Handbook of Experimental Pharmacology68 citations
Semantic Scholar
GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis
M. Biagioli, Adriana Carino, C. Fiorucci, S. Marchianò +8 more
2019Cellular and Molecular Gastroenterology and Hepatology64 citations Open access
Semantic Scholar
Immunomodulatory functions of FXR.
S. Fiorucci, A. Zampella, Patrizia Ricci, E. Distrutti +1 more
2022Molecular and Cellular Endocrinology63 citations
Semantic Scholar
Chenodeoxycholic Acid: An Update on Its Therapeutic Applications.
S. Fiorucci, E. Distrutti
2019Handbook of Experimental Pharmacology62 citations
Semantic Scholar
Bile acid-activated receptors and the regulation of macrophages function in metabolic disorders.
S. Fiorucci, Monia Baldoni, Patrizia Ricci, A. Zampella +2 more
2020Current opinion in pharmacology (Print)60 citations
Semantic Scholar
Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH.
Adriana Carino, M. Biagioli, S. Marchianò, C. Fiorucci +6 more
2019Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids54 citations
Semantic Scholar
Microbial-derived bile acid reverses inflammation in IBD via GPBAR1 agonism and RORγt inverse agonism.
M. Biagioli, C. Di Giorgio, Carmen Massa, S. Marchianò +19 more
2024Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie51 citations Open access
Semantic Scholar
Endocrine activities and adipogenic effects of bisphenol AF and its main metabolite.
D. G. Skledar, Adriana Carino, J. Trontelj, Johanna Troberg +7 more
2019Chemosphere50 citations Open access
Semantic Scholar
Opposite effects of the FXR agonist obeticholic acid on Mafg and Nrf2 mediate the development of acute liver injury in rodent models of cholestasis.
Adriana Carino, M. Biagioli, S. Marchianò, C. Fiorucci +10 more
2020Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids44 citations
Semantic Scholar
TRPM8 indicates poor prognosis in colorectal cancer patients and its pharmacological targeting reduces tumour growth in mice by inhibiting Wnt/β‐catenin signalling
E. Pagano, B. Romano, D. Cicia, F. Iannotti +18 more
2022British Journal of Pharmacology40 citations Open access
Semantic Scholar
Linking liver metabolic and vascular disease via bile acid signaling.
S. Fiorucci, E. Distrutti
2021Trends in Molecular Medicine37 citations
Semantic Scholar
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity
M. Biagioli, Adriana Carino, C. Fiorucci, S. Marchianò +7 more
2020Journal of Immunology37 citations Open access
Semantic Scholar
Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH
S. Marchianò, M. Biagioli, E. Morretta, C. Di Giorgio +9 more
2023Scientific Reports35 citations Open access
Semantic Scholar
Divergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic Properties
M. Biagioli, Daniela Capobianco, Adriana Carino, S. Marchianò +4 more
2019Nutrients33 citations Open access
Semantic Scholar
Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation
Adriana Carino, S. Marchianò, M. Biagioli, C. Fiorucci +9 more
2019Nutrients32 citations Open access
Semantic Scholar
Bile acid activated receptors: Integrating immune and metabolic regulation in non-alcoholic fatty liver disease
M. Biagioli, S. Fiorucci
2021Liver Research31 citations Open access
Semantic Scholar
Beneficial effects of UDCA and norUDCA in a rodent model of steatosis are linked to modulation of GPBAR1/FXR signaling.
S. Marchianò, M. Biagioli, Rosalinda Roselli, A. Zampella +8 more
2022Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids30 citations
Semantic Scholar
Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury
M. Biagioli, S. Marchianò, C. Di Giorgio, Rosalinda Roselli +10 more
2022Hepatology30 citations Open access
Semantic Scholar
Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G‐Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease
S. Marchianò, M. Biagioli, M. Bordoni, E. Morretta +17 more
2023Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease28 citations Open access
Semantic Scholar
Bile acids and their receptors in hepatic immunity
S. Fiorucci, S. Marchianò, E. Distrutti, M. Biagioli
2025Liver Research27 citations Open access
Semantic Scholar
Current Landscape and Evolving Therapies for Primary Biliary Cholangitis
S. Fiorucci, G. Urbani, C. Di Giorgio, M. Biagioli +1 more
2024Cells27 citations Open access
Semantic Scholar
Activation of GPBAR1 attenuates vascular inflammation and atherosclerosis in a mouse model of NAFLD-related cardiovascular disease.
M. Biagioli, S. Marchianò, C. Di Giorgio, M. Bordoni +19 more
2023Biochemical Pharmacology27 citations Open access
Semantic Scholar
The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions
M. Biagioli, Adriana Carino, C. Fiorucci, Giannamaria Annunziato +12 more
2019Nutrients27 citations Open access
Semantic Scholar
The identification of farnesoid X receptor modulators as treatment options for nonalcoholic fatty liver disease
S. Fiorucci, M. Biagioli, Monia Baldoni, Patrizia Ricci +3 more
2021Expert Opinion on Drug Discovery26 citations
Semantic Scholar
Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential
Adriana Carino, L. Graziosi, S. Marchianò, M. Biagioli +6 more
2021bioRxiv25 citations Open access
Semantic Scholar
Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics
Bianca Fiorillo, S. Marchianò, Federica Moraca, V. Sepe +7 more
2021Journal of Chemical Information and Modeling23 citations Open access
Semantic Scholar
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy
Adriana Carino, S. Marchianò, M. Biagioli, P. Scarpelli +8 more
2020The FASEB Journal22 citations
Semantic Scholar
Hijacking SARS-Cov-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on receptor binding region
Adriana Carino, Federica Moraca, Bianca Fiorillo, S. Marchianò +9 more
2020bioRxiv22 citations Open access
Semantic Scholar
Phenotyping the Chemical Communications of the Intestinal Microbiota and the Host: Secondary Bile Acids as Postbiotics
G. Urbani, E. Rondini, E. Distrutti, S. Marchianò +2 more
2025Cells21 citations Open access
Semantic Scholar
Bile Acids Serve As Endogenous Antagonists Of The Leukemia Inhibitory Factor (LIF) Receptor in Oncogenesis
C. Di Giorgio, E. Morretta, A. Lupia, Rachele Bellini +18 more
2023bioRxiv21 citations Open access
Semantic Scholar
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders.
S. Fiorucci, V. Sepe, M. Biagioli, Bianca Fiorillo +3 more
2023Biochemical Pharmacology21 citations
Semantic Scholar
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer
C. Di Giorgio, Rachele Bellini, A. Lupia, Carmen Massa +20 more
2023Cellular Oncology21 citations Open access
Semantic Scholar
Serum Bile Acid Levels Before and After Sleeve Gastrectomy and Their Correlation with Obesity-Related Comorbidities
S. De Vuono, M. Ricci, Elisa Nulli Migliola, M. Monti +7 more
2019Obesity Surgery21 citations
Semantic Scholar
Bile Acids-Based Therapies for Primary Sclerosing Cholangitis: Current Landscape and Future Developments
S. Fiorucci, G. Urbani, C. Di Giorgio, M. Biagioli +1 more
2024Cells20 citations Open access
Semantic Scholar
Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling
S. Marchianò, M. Biagioli, Rosalinda Roselli, A. Zampella +7 more
2021The FASEB Journal19 citations Open access
Semantic Scholar
Allo-lithocholic acid, a microbiome derived secondary bile acid, attenuates liver fibrosis.
S. Marchianò, M. Biagioli, C. Di Giorgio, Carmen Massa +10 more
2025Biochemical Pharmacology18 citations Open access
Semantic Scholar
Bile acids and bile acid activated receptors in the treatment of Covid-19.
S. Fiorucci, G. Urbani, M. Biagioli, V. Sepe +2 more
2023Biochemical Pharmacology18 citations Open access
Semantic Scholar
Liver GPBAR1 Associates With Immune Dysfunction in Primary Sclerosing Cholangitis and Its Activation Attenuates Cholestasis in Abcb4−/− Mice
C. Di Giorgio, G. Urbani, S. Marchianò, M. Biagioli +16 more
2025Liver international (Print)17 citations Open access
Semantic Scholar
Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma
C. Di Giorgio, A. Lupia, S. Marchianò, M. Bordoni +13 more
2022Cells17 citations Open access
Semantic Scholar
GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation
M. Biagioli, S. Marchianò, Rosalinda Roselli, C. Di Giorgio +8 more
2022Cells17 citations Open access
Semantic Scholar
Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis
C. Di Giorgio, S. Marchianò, E. Marino, M. Biagioli +9 more
2022Frontiers in Oncology16 citations Open access
Semantic Scholar
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
C. Di Giorgio, Rachele Bellini, A. Lupia, Carmen Massa +15 more
2023Frontiers in Oncology15 citations Open access
Semantic Scholar
Development of dual GPBAR1 agonist and RORγt inverse agonist for the treatment of inflammatory bowel diseases.
M. Biagioli, C. Di Giorgio, E. Morretta, Rachele Bellini +10 more
2024Pharmacological Research14 citations Open access
Semantic Scholar

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E. Distrutti×47
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E. Distrutti — researcher profile on SciRah
M. Biagioli×43
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M. Biagioli — researcher profile on SciRah
A. Zampella×34
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S. Marchianò×34
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Adriana Carino — researcher profile on SciRah

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Rachele Bellini — researcher profile on SciRah

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E. Morretta — researcher profile on SciRah