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W. Kamphuis · SciRah

Researcher profile · Semantic Scholar

W. Kamphuis

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W. Kamphuis — researcher profile on SciRah

h-index: 48
Works: 129
Citations: 7,350

Most-cited papers

Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
I. Holtman, D. D. A. Raj, Jeremy A. Miller, W. Schaafsma +9 more
2015Acta Neuropathologica Communications565 citations Open access
Semantic Scholar
Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction.
M. Orre, W. Kamphuis, Lana M. Osborn, A. H. Jansen +3 more
2014Neurobiology of Aging384 citations
Semantic Scholar
GFAP Isoforms in Adult Mouse Brain with a Focus on Neurogenic Astrocytes and Reactive Astrogliosis in Mouse Models of Alzheimer Disease
W. Kamphuis, Carlyn Mamber, M. Moeton, L. Kooijman +9 more
2012PLoS ONE302 citations Open access
Semantic Scholar
Astrogliosis: An integral player in the pathogenesis of Alzheimer's disease.
Lana M. Osborn, W. Kamphuis, W. Wadman, E. Hol
2016Progress in neurobiology297 citations Open access
Semantic Scholar
Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice.
M. Orre, W. Kamphuis, Lana M. Osborn, J. Melief +5 more
2014Neurobiology of Aging277 citations
Semantic Scholar
Gene expression analysis in the human hypothalamus in depression by laser microdissection and real-time PCR: the presence of multiple receptor imbalances
S.-S. Wang, W. Kamphuis, I. Huitinga, J.-N. Zhou +1 more
2008Molecular Psychiatry253 citations
Semantic Scholar
Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease.
W. Kamphuis, J. Middeldorp, L. Kooijman, J. Sluijs +5 more
2014Neurobiology of Aging239 citations Open access
Semantic Scholar
Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease.
Zhuoran Yin, D. D. A. Raj, N. Saiepour, D. Dam +11 more
2017Neurobiology of Aging225 citations Open access
Semantic Scholar
Enteric GFAP expression and phosphorylation in Parkinson's disease
T. Clairembault, W. Kamphuis, L. Leclair-Visonneau, M. Rolli-Derkinderen +4 more
2014Journal of Neurochemistry190 citations Open access
Semantic Scholar
Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease.
W. Kamphuis, L. Kooijman, Sjoerd T. T. Schetters, M. Orre +1 more
2016Biochimica et Biophysica Acta187 citations Open access
Semantic Scholar
Reactive glia show increased immunoproteasome activity in Alzheimer's disease.
M. Orre, W. Kamphuis, S. Dooves, L. Kooijman +8 more
2013Brain : a journal of neurology176 citations Open access
Semantic Scholar
Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer’s disease
M. J. Végh, C. M. Heldring, W. Kamphuis, Sara Hijazi +7 more
2014Acta Neuropathologica Communications166 citations Open access
Semantic Scholar
GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild‐type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease
W. Kamphuis, L. Kooijman, M. Orre, O. Stassen +2 more
2015Glia147 citations Open access
Semantic Scholar
Differential cell proliferation in the cortex of the appsweps1de9 alzheimer's disease mouse model
W. Kamphuis, M. Orre, L. Kooijman, M. Dahmen +1 more
2012Glia140 citations
Semantic Scholar
Deep brain stimulation and the role of astrocytes
V. Vedam-Mai, E. V. van Battum, W. Kamphuis, M. Feenstra +4 more
2012Molecular Psychiatry137 citations Open access
Semantic Scholar
Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: a comparison with lentiviral vectors.
A. Harvey, W. Kamphuis, R. Eggers, Natalie A. Symons +4 more
2002Molecular and cellular neurosciences116 citations
Semantic Scholar
Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell‐type‐specific
A. H. Jansen, Maurik van Hal, Ilse C. Op den Kelder, Romy T. Meier +12 more
2016Glia106 citations Open access
Semantic Scholar
Circadian expression of clock genes and clock-controlled genes in the rat retina.
W. Kamphuis, C. Cailotto, F. Dijk, A. Bergen +1 more
2005Biochemical and Biophysical Research Communications - BBRC104 citations
Semantic Scholar
Aberrant stress hormone receptor balance in the human prefrontal cortex and hypothalamic paraventricular nucleus of depressed patients.
Xin-Rui Qi, W. Kamphuis, Shan-Shan Wang, Qian Wang +3 more
2013Psychoneuroendocrinology102 citations
Semantic Scholar
Rat Hippocampal Kindling Induces Changes in the Glutamate Receptor mRNA Expression Patterns in Dentate Granule Neurons
W. Kamphuis, T. C. Rijk, L. Talamini, F. Lopes da Silva
1994European Journal of Neuroscience102 citations
Semantic Scholar
A Single Amino Acid Substitution (Cys249Trp) in Crb1 Causes Retinal Degeneration and Deregulates Expression of Pituitary Tumor Transforming Gene Pttg1
S. A. van de Pavert, J. Meuleman, A. Malysheva, W. Aartsen +6 more
2007Journal of Neuroscience86 citations Open access
Semantic Scholar
Expression of GABA-A receptor subunit in mRNAs in hippocampal pyramidal and granular neurons in the kindling model of epileptogenesis: an in situ hybridization study.
W. Kamphuis, .c. De Rijk, F. Lopes da Silva
200386 citations
Semantic Scholar
Nitric oxide/guanylate cyclase pathways and flow in anterior segment perfusion
A. Schneemann, B. G. Dijkstra, T. van den Berg, W. Kamphuis +1 more
2002Graefe's Archive for Clinical and Experimental Ophthalmology83 citations
Semantic Scholar
Comparison of human retinal pigment epithelium gene expression in macula and periphery highlights potential topographic differences in Bruch's membrane.
S. van Soest, G. D. de Wit, Anke H. W. Essing, J. T. ten Brink +3 more
2007Molecular Vision77 citations
Semantic Scholar
Diabetes changes the levels of ionotropic glutamate receptors in the rat retina
A. R. Santiago, J. Gaspar, F. Baptista, A. Cristóvão +3 more
2009Molecular Vision75 citations
Semantic Scholar
Cortical beta amyloid protein triggers an immune response, but no synaptic changes in the APPswe/PS1dE9 Alzheimer's disease mouse model.
Kerstin T. S. Wirz, K. Bossers, A. Stargardt, W. Kamphuis +3 more
2013Neurobiology of Aging73 citations Open access
Semantic Scholar
Gene expression of GABA and glutamate pathway markers in the prefrontal cortex of non-suicidal elderly depressed patients.
J. Zhao, A. Bao, Xin-Rui Qi, W. Kamphuis +3 more
2012Journal of Affective Disorders73 citations
Semantic Scholar
Reduced amyloid‐β degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg‐AD mouse models
A. Stargardt, J. Gillis, W. Kamphuis, A. Wiemhoefer +6 more
2013Aging Cell70 citations Open access
Semantic Scholar
GFAPδ Expression in Glia of the Developmental and Adolescent Mouse Brain
Carlyn Mamber, W. Kamphuis, Nina L. Haring, N. Peprah +2 more
2012PLoS ONE69 citations Open access
Semantic Scholar
Prostanoid receptor gene expression profile in human trabecular meshwork: a quantitative real-time PCR approach.
W. Kamphuis, A. Schneemann, L. van Beek, A. Smit +2 more
2001Investigative Ophthalmology and Visual Science64 citations
Semantic Scholar
GAP-43 expression is upregulated in retinal ganglion cells after ischemia/reperfusion-induced damage.
F. Dijk, A. Bergen, W. Kamphuis
2007Experimental Eye Research59 citations
Semantic Scholar
Reactive astrocytes as treatment targets in Alzheimer's disease—Systematic review of studies using the APPswePS1dE9 mouse model
Tamar Smit, Natasja A. C. Deshayes, D. Borchelt, W. Kamphuis +2 more
2021Glia58 citations Open access
Semantic Scholar
Ischemia-induced changes of AMPA-type glutamate receptor subunit expression pattern in the rat retina: a real-time quantitative PCR study.
F. Dijk, Elza Kraal-Muller, W. Kamphuis
2004Investigative Ophthalmology and Visual Science55 citations Open access
Semantic Scholar
N-methyl-D-aspartate and kainate receptor gene expression in hippocampal pyramidal and granular neurons in the kindling model of epileptogenesis.
W. Kamphuis, H. Hendriksen, P. Diegenbach, F. Lopes da Silva
1995Neuroscience54 citations Open access
Semantic Scholar
Intermediate filament transcription in astrocytes is repressed by proteasome inhibition
J. Middeldorp, W. Kamphuis, J. Sluijs, Dalila Achoui +8 more
2009The FASEB Journal51 citations Open access
Semantic Scholar
Diabetes changes ionotropic glutamate receptor subunit expression level in the human retina.
A. R. Santiago, J. M. Hughes, W. Kamphuis, R. Schlingemann +1 more
2008Brain Research51 citations Open access
Semantic Scholar
Elevation of nitric oxide production in human trabecular meshwork by increased pressure
A. Schneemann, Ateunette Leusink-Muis, T. Berg, P. F. Hoyng +1 more
2003Graefe's Archive for Clinical and Experimental Ophthalmology51 citations
Semantic Scholar
Global gene expression profiling of ischemic preconditioning in the rat retina
W. Kamphuis, F. Dijk, S. van Soest, A. Bergen
2007Molecular Vision48 citations
Semantic Scholar
Different stress-related gene expression in depression and suicide.
J. Zhao, Xin-Rui Qi, S.-F. Gao, J. Lu +4 more
2015Journal of Psychiatric Research46 citations
Semantic Scholar
An immunocytochemical study on specific amacrine cell subpopulations in the rat retina after ischemia.
F. Dijk, W. Kamphuis
2004Brain Research46 citations
Semantic Scholar
Differential effects of ischemia/reperfusion on amacrine cell subtype-specific transcript levels in the rat retina.
F. Dijk, Selina M. van Leeuwen, W. Kamphuis
2004Brain Research44 citations
Semantic Scholar
Presenilin mouse and zebrafish models for dementia: focus on neurogenesis.
P. Tijn, W. Kamphuis, M. Marlatt, E. Hol +1 more
2011Progress in neurobiology43 citations Open access
Semantic Scholar
Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes
Daniela Herrera Moro Chao, W. Kallemeijn, A. Marques, M. Orre +13 more
2015PLoS ONE41 citations Open access
Semantic Scholar
Opposite Changes in GABAA Receptor Function in the CA1‐3 Area and Fascia Dentata of Kindled Rat Hippocampus
M. Titulaer, W. Ghijsen, W. Kamphuis, T. D. de Rijk +1 more
1995Journal of Neurochemistry40 citations
Semantic Scholar
GABAA receptor β1–3 subunit gene expression in the hippocampus of kindled rats
W. Kamphuis, T. D. de Rijk, F. Lopes da Silva
199440 citations Open access
Semantic Scholar
Ischemic preconditioning alters the pattern of gene expression changes in response to full retinal ischemia.
W. Kamphuis, F. Dijk, A. Bergen
2007Molecular Vision37 citations
Semantic Scholar
Expression patterns of voltage-dependent calcium channel α1 subunits (α1A–α1E) mRNA in rat retina
W. Kamphuis, H. Hendriksen
199837 citations
Semantic Scholar
Ischemia-induced alterations of AMPA-type glutamate receptor subunit. Expression patterns in the rat retina--an immunocytochemical study.
F. Dijk, W. Kamphuis
2004Brain Research36 citations
Semantic Scholar
Long-term and regional specific changes in [3H]flunitrazepam binding in kindled rat hippocampus.
M. Titulaer, W. Kamphuis, F. D. da Silva
1995Neuroscience35 citations Open access
Semantic Scholar
Astrocyte Changes in the Prefrontal Cortex From Aged Non-suicidal Depressed Patients
Xin-Rui Qi, W. Kamphuis, Shan Ling
2019Frontiers in Cellular Neuroscience34 citations Open access
Semantic Scholar

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