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W. Ghijsen · SciRah

Researcher profile · Semantic Scholar

W. Ghijsen

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W. Ghijsen — researcher profile on SciRah

h-index: 32
Works: 80
Citations: 2,420

Most-cited papers

Differential release of amino acids, neuropeptides, and catecholamines from isolated nerve terminals.
M. Verhage, H. McMahon, W. Ghijsen, F. Boomsma +3 more
1991Neuron329 citations
Semantic Scholar
Rab3a is involved in transport of synaptic vesicles to the active zone in mouse brain nerve terminals.
A. G. Miriam Leenders, F. Lopes da Silva, W. Ghijsen, M. Verhage
2001Molecular Biology of the Cell120 citations Open access
Semantic Scholar
ATP-dependent calcium transport and its correlation with Ca2+ -ATPase activity in basolateral plasma membranes of rat duodenum.
W. Ghijsen, M. D. de Jong, C. H. van Os
1982Biochimica et Biophysica Acta103 citations
Semantic Scholar
Altered hippocampal gene expression prior to the onset of spontaneous seizures in the rat post‐status epilepticus model
H. Hendriksen, N. Datson, W. Ghijsen, E. V. van Vliet +3 more
2001European Journal of Neuroscience94 citations
Semantic Scholar
Dynamics of munc18‐1 phosphorylation/dephosphorylation in rat brain nerve terminals
K. de Vries, Arwin Geijtenbeek, E. C. Brian, P. D. de Graan +2 more
2000European Journal of Neuroscience88 citations
Semantic Scholar
Ca2+‐Dependent Regulation of Presynaptic Stimulus‐Secretion Coupling
M. Verhage, E. Besselsen, Fernando H. Lopes Silvas, W. Ghijsen
1989Journal of Neurochemistry86 citations
Semantic Scholar
Kinetic properties of Na+/Ca2+ exchange in basolateral plasma membranes of rat small intestine.
W. Ghijsen, M. D. de Jong, C. H. van Os
1983Biochimica et Biophysica Acta83 citations
Semantic Scholar
1 alpha, 25-Dihydroxy-vitamin D-3 regulates ATP-dependent calcium transport in basolateral plasma membranes of rat enterocytes.
W. Ghijsen, C. H. van Os
1982Biochimica et Biophysica Acta80 citations
Semantic Scholar
A presynaptic N‐methyl‐d‐aspartate autoreceptor in rat hippocampus modulating amino acid release from a cytoplasmic pool
A. Breukel, E. Besselsen, F. L. da Silva, W. Ghijsen
1998European Journal of Neuroscience78 citations
Semantic Scholar
Dissociation between Ca2+-ATPase and alkaline phosphatase activities in plasma membranes of rat duodenum.
W. Ghijsen, M. D. de Jong, C. H. van Os
1980Biochimica et Biophysica Acta68 citations
Semantic Scholar
Glutamate transporters alterations in the reorganizing dentate gyrus are associated with progressive seizure activity in chronic epileptic rats
J. Gorter, E. V. van Vliet, E. A. Proper, P. D. de Graan +3 more
2002The Journal of comparative neurology62 citations
Semantic Scholar
Evaluation of the Ca2+ Concentration in Purified Nerve Terminals: Relationship Between Ca2+ Homeostasis and Synaptosomal Preparation
M. Verhage, E. Besselsen, F. L. da Silva, W. Ghijsen
1988Journal of Neurochemistry59 citations
Semantic Scholar
Kindling increases the K(+)-evoked Ca2(+)-dependent release of endogenous GABA in area CA1 of rat hippocampus.
W. Kamphuis, E. Huisman, A. M. C. Dreijer, W. Ghijsen +2 more
1990Brain Research56 citations
Semantic Scholar
Characterization of the Release of Cholecystokinin‐8 from Isolated Nerve Terminals and Comparison with Exocytosis of Classical Transmitters
M. Verhage, W. Ghijsen, David G. Nicholls, V. Wiegant
1991Journal of Neurochemistry55 citations
Semantic Scholar
Presynaptic plasticity: the regulation of Ca(2+)-dependent transmitter release.
Matthujs Verhage, W. Ghijsen, F. Lopes da Silva
1994Progress in neurobiology49 citations Open access
Semantic Scholar
Phosphorylated intermediates of Ca2+ -ATPase and alkaline phosphatase in plasma membranes from rat duodenal epithelium.
H. D. de Jonge, W. Ghijsen, C. H. van Os
1981Biochimica et Biophysica Acta47 citations
Semantic Scholar
Ca-stimulated ATPase in brush border and basolateral membranes of rat duodenum with high affinity sites for Ca ions
W. Ghijsen, C. H. van Os
1979Nature44 citations
Semantic Scholar
Evidence for a Role of Protein Kinase C Substrate B‐50 (GAP‐43) in Ca2+‐Induced Neuropeptide Cholecystokinin‐8 Release from Permeated Synaptosomes
J. J. Hens, W. Ghijsen, W. Dimjati, V. Wiegant +3 more
199343 citations
Semantic Scholar
Ca2+-stimulated, Mg2+-independent ATP hydrolysis and the high affinity Ca2+-pumping ATPase. Two different activities in rat kidney basolateral membranes.
W. Ghijsen, Piotr Gmaj, H. Murer
1984Biochimica et Biophysica Acta43 citations
Semantic Scholar
Opposite Changes in GABAA Receptor Function in the CA1‐3 Area and Fascia Dentata of Kindled Rat Hippocampus
M. Titulaer, W. Ghijsen, W. Kamphuis, T. D. de Rijk +1 more
1995Journal of Neurochemistry40 citations
Semantic Scholar
Differential signaling in presynaptic neurotransmitter release
W. Ghijsen, A. G. Miriam Leenders
2005Cellular and Molecular Life Sciences (CMLS)39 citations
Semantic Scholar
Neurotransmitter release from tottering mice nerve terminals with reduced expression of mutated P‐ and Q‐type Ca2+‐channels
A. G. Miriam Leenders, A. M. van den Maagdenberg, F. L. da Silva, Zu-Hang Sheng +2 more
2002European Journal of Neuroscience38 citations
Semantic Scholar
Endogenous Noradrenaline and Dopamine in Nerve Terminals of the Hippocampus: Differences in Levels and Release Kinetics
M. Verhage, W. Ghijsen, F. Boomsma, F. Lopes da Silva
1992Journal of Neurochemistry37 citations
Semantic Scholar
Monitoring extracellular glutamate in hippocampal slices with a microsensor.
W. H. Oldenziel, M. van der Zeyden, Gerard Dijkstra, W. Ghijsen +3 more
2007Journal of Neuroscience Methods36 citations
Semantic Scholar
Activity‐dependent neurotransmitter release kinetics: correlation with changes in morphological distributions of small and large vesicles in central nerve terminals
A. G. Miriam Leenders, G. Scholten, V. Wiegant, F. L. da Silva +1 more
1999European Journal of Neuroscience36 citations
Semantic Scholar
Sequential changes in synaptic vesicle pools and endosome-like organelles during depolarization near the active zone of central nerve terminals.
A. Leenders, G. Scholten, R. P. D. de Lange, F. Lopes da Silva +1 more
2002Neuroscience34 citations
Semantic Scholar
Regulation of Vesicle Traffic and Neurotransmitter Release in Isolated Nerve Terminals
W. Ghijsen, A. G. Miriam Leenders, F. Lopes da Silva
2003Neurochemical Research33 citations
Semantic Scholar
Effects of uptake carrier blockers SK & F 89976-A and L-trans-PDC on in vivo release of amino acids in rat hippocampus.
M. Zuiderwijk, Estevan Veenstra, F. L. da Silva, W. Ghijsen
1996European Journal of Pharmacology33 citations
Semantic Scholar
Compensatory change in EAAC1 glutamate transporter in rat hippocampus CA1 region during kindling epileptogenesis.
W. Ghijsen, A. I. da Silva Aresta Belo, M. Zuiderwijk, F. H. Lopez da Silva
1999Neuroscience Letters32 citations
Semantic Scholar
Cholecystokinin (CCK-8) modulates vesicular release of excitatory amino acids in rat hippocampal nerve endings.
A. Breukel, F. Lopes da Silva, W. Ghijsen
1997Neuroscience Letters32 citations
Semantic Scholar
Synaptosomes: a model system to study release of multiple classes of neurotransmitters
A. I. M. Breukel, C. E. Besselsen, W. Ghijsen
199632 citations
Semantic Scholar
Presynaptic Mechanism of Action of 4‐Aminopyridine: Changes in Intracellular Free Ca2+ Concentration and Its Relationship to B‐50 (GAP‐43) Phosphorylation
F. Heemskerk, L. Schrama, W. Ghijsen, P. Graan +2 more
1991Journal of Neurochemistry32 citations
Semantic Scholar
Enhancement of Endogenous Release of Glutamate and γ‐Aminobutyric Acid from Hippocampus CA1 Slices After In Vivo Long‐Term Potentiation
W. Ghijsen, E. Besselsen, V. Geukers, W. Kamphuis +1 more
1992Journal of Neurochemistry31 citations
Semantic Scholar
Regulation of cholecystokinin release from central nerve terminals.
W. Ghijsen, A. G. Miriam Leenders, V. Wiegant
2001Peptides30 citations
Semantic Scholar
Chlamydomonas contains calcium stores that are mobilized when phospholipase C is activated
H. Kuin, H. Koerten, W. Ghijsen, T. Munnik +2 more
2000Planta29 citations
Semantic Scholar
GABAA Receptor Function in the Early Period After Transient Forebrain Ischaemia in the Rat
H. B. Verheul, F. Leeuw, G. Scholten, C. Tulleken +2 more
1993European Journal of Neuroscience29 citations
Semantic Scholar
Ba2+ replaces Ca2+/calmodulin in the activation of protein phosphatases and in exocytosis of all major transmitters.
M. Verhage, J. J. Hens, P. D. de Graan, F. Boomsma +4 more
1995European Journal of Pharmacology28 citations Open access
Semantic Scholar
Role of Calcineurin in Ca2+‐Induced Release of Catecholamines and Neuropeptides
J. J. Hens, M. de Wit, W. Ghijsen, A. G. Miriam Leenders +6 more
1998Journal of Neurochemistry24 citations Open access
Semantic Scholar
Arachidonic acid inhibits uptake of amino acids and potentiates PKC effects on glutamate, but not GABA, exocytosis in isolated hippocampal nerve terminals.
A. Breukel, E. Besselsen, F. Lopes da Silva, W. Ghijsen
1997Brain Research23 citations
Semantic Scholar
Regulation of duodenal Ca2+ pump by calmodulin and vitamin D-dependent Ca2+-binding protein.
W. Ghijsen, C. H. van Os, C. Heizmann, H. Murer
1986American Journal of Physiology22 citations
Semantic Scholar
Presynaptic Modulation of Cholecystokinin Release by Protein Kinase C in the Rat Hippocampus
A. Breukel, V. Wiegant, F. Lopes da Silva, W. Ghijsen
1998Journal of Neurochemistry20 citations
Semantic Scholar
Anti-B-50 (GAP-43) antibodies decrease exocytosis of glutamate in permeated synaptosomes.
J. J. Hens, W. Ghijsen, Ulrich Weller, H. Spierenburg +4 more
1998European Journal of Pharmacology19 citations
Semantic Scholar
Separation of basolateral plasma membranes from smooth endoplasmic reticulum of the rat enterocyte by zonal electrophoresis on density gradients.
C. H. van Os, H. D. de Jonge, M. D. de Jong, W. Ghijsen +1 more
1980Biochimica et Biophysica Acta16 citations
Semantic Scholar
Mechanism-Based Modeling of Functional Adaptation Upon Chronic Treatment with Midazolam
A. Cleton, Jonas Ödman, P. H. van der Graaf, W. Ghijsen +2 more
2000Pharmaceutical Research14 citations
Semantic Scholar
Perfusion of Immobilized Isolated Nerve Terminals as a Model for the Regulation of Transmitter Release: Release of Different, Endogenous Transmitters, Repeated Stimulation, and High Time Resolution
M. Verhage, H. Sandman, Fred Mosselveld, M. Velde +3 more
1992Journal of Neurochemistry14 citations
Semantic Scholar
Calcium uptake into rat small intestinal brush border membrane vesicles: characterization of transmembrane calcium transport at short initial incubation times.
W. Ghijsen, U. Ganguli, G. Stange, Piotr Gmaj +1 more
1987Cell Calcium13 citations
Semantic Scholar
Activity-dependent recruitment of endogenous glutamate for exocytosis.
M. Verhage, F. Lopes da Silva, W. Ghijsen
1991Neuroscience12 citations
Semantic Scholar
Electrically evoked GABA release in rat hippocampus CA1 region and its changes during kindling epileptogenesis.
W. Ghijsen, M. Zuiderwijk, F. Lopes da Silva
2007Brain Research9 citations
Semantic Scholar
Mechanism-Based Modeling of Adaptive Changes in the Pharmacodynamics of Midazolam in the Kindling Model of Epilepsy
A. Cleton, P. H. van der Graaf, W. Ghijsen, R. Voskuyl +1 more
1999Pharmaceutical Research7 citations
Semantic Scholar
Characterization of the release of Met-enkephalin from isolated nerve terminals: release kinetics and cation-dependence.
M. Verhage, W. Ghijsen, V. Wiegant
1992Brain Research7 citations
Semantic Scholar

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M. Verhage×12
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C. H. van Os×8
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A. G. Miriam Leenders

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E. Besselsen×5

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