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T. Grasela · SciRah

Researcher profile · Semantic Scholar

T. Grasela

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T. Grasela — researcher profile on SciRah

h-index: 34
Works: 113
Citations: 3,769

Most-cited papers

Hemodynamic effects of propofol: data from over 25,000 patients.
C. Hug, C. Mcleskey, M. Nahrwold, M. Roizen +6 more
1993Anesthesia and Analgesia291 citations
Semantic Scholar
Pharmacodynamics of Fluoroquinolones againstStreptococcus pneumoniae in Patients with Community-Acquired Respiratory Tract Infections
P. Ambrose, D. Grasela, T. Grasela, J. Passarell +2 more
2001Antimicrobial Agents and Chemotherapy217 citations Open access
Semantic Scholar
The clinical evaluation of new drugs for sepsis. A prospective study design based on survival analysis.
W. Knaus, F. Harrell, Charles J. Fisher, D. Wagner +6 more
1993Journal of the American Medical Association (JAMA)206 citations
Semantic Scholar
The pharmacokinetic and pharmacodynamic profile of tigecycline.
A. Meagher, P. Ambrose, T. Grasela, E. Ellis-Grosse
2005Clinical Infectious Diseases198 citations Open access
Semantic Scholar
Symptomatic Cardiotoxicity Associated with 5‐Fluorouracil
Christine C. Meyer, K. Calis, L. Burke, C. Walawander +1 more
1997Pharmacotherapy173 citations
Semantic Scholar
Pharmacokinetic/pharmacodynamic profile for tigecycline-a new glycylcycline antimicrobial agent.
A. Meagher, P. Ambrose, T. Grasela, E. Ellis-Grosse
2005Diagnostic microbiology and infectious disease133 citations
Semantic Scholar
Pharmacodynamics of Fluoroquinolones against Streptococcus pneumoniae in Patients with Community-Acquired Respiratory Tract Infections
P. Ambrose, D. Grasela, T. Grasela, J. Passarell +2 more
2001119 citations
Semantic Scholar
Inhibition of enoxacin absorption by antacids or ranitidine
T. Grasela, Jerome J. Schentag, A. Sedman, J. Wilton +4 more
1989Antimicrobial Agents and Chemotherapy99 citations Open access
Semantic Scholar
Population Pharmacokinetic Analysis of Linezolid in Patients With Infectious Disease: Application to Lower Body Weight and Elderly Patients
Sadahiro Abe, K. Chiba, B. Cirincione, T. Grasela +2 more
2009Journal of clinical pharmacology98 citations
Semantic Scholar
Pretreatment regimens for adverse events related to infusion of amphotericin B.
S. Goodwin, J. Cleary, C. Walawander, J. Taylor +1 more
1995Clinical Infectious Diseases94 citations
Semantic Scholar
Relationship between drug exposure and the efficacy and safety of bupropion sustained release for smoking cessation.
J. Johnston, J. Fiedler-Kelly, E. Glover, D. Sachs +2 more
2001Nicotine & Tobacco Research89 citations
Semantic Scholar
The initial clinical experience of 1819 physicians in maintaining anesthesia with propofol: characteristics associated with prolonged time to awakening.
J. Apfelbaum, T. Grasela, C. C. Hug, C. Mcleskey +6 more
1993Anesthesia and Analgesia81 citations
Semantic Scholar
Eliminating Intensive Postoperative Care in Same-day Surgery Patients Using Short-acting Anesthetics
J. Apfelbaum, C. Walawander, T. Grasela, P. Wise +4 more
2002Anesthesiology79 citations
Semantic Scholar
Pharmacokinetic/Pharmacodynamic Modeling and Simulation of Neutropenia during Phase I Development of Liposome-Entrapped Paclitaxel
Gerald J. Fetterly, T. Grasela, J. Sherman, J. L. Dul +8 more
2008Clinical Cancer Research68 citations Open access
Semantic Scholar
Adverse reaction reporting of interaction between warfarin and fluoroquinolones.
Heidi M. Jolson, L. Tanner, L. Green, T. Grasela
1991Archives of Internal Medicine62 citations
Semantic Scholar
Gatifloxacin and the elderly: pharmacokinetic-pharmacodynamic rationale for a potential age-related dose reduction.
P. Ambrose, S. Bhavnani, B. Cirincione, M. Piedmonte +1 more
2003Journal of Antimicrobial Chemotherapy61 citations Open access
Semantic Scholar
A randomized, controlled trial of parenteral clindamycin in neonatal necrotizing enterocolitis.
R. Faix, T. Polley, T. Grasela
1988Jornal de Pediatria60 citations
Semantic Scholar
Population Pharmacokinetics of Lamotrigine Adjunctive Therapy in Adults with Epilepsy
T. Grasela, J. Fiedler-Kelly, E. Cox, Gilda P. Womble +2 more
1999Journal of clinical pharmacology58 citations
Semantic Scholar
Adverse events in a multicenter phase IV study of propofol: evaluation by anesthesiologists and postanesthesia care unit nurses.
C. Mcleskey, C. Walawander, M. Nahrwold, M. Roizen +6 more
1993Anesthesia and Analgesia56 citations
Semantic Scholar
An evaluation of population pharmacokinetics in therapeutic trials. Part II. Detection of a drug‐drug interaction
T. Grasela, E. Antal, L. Ereshefsky, B. G. Wells +2 more
1987Clinical pharmacology and therapy52 citations
Semantic Scholar
Prospective Surveillance of Intravenous Amphotericin B Use Patterns
T. Grasela, S. Goodwin, M. Walawander, R. Cramer +2 more
1990Pharmacotherapy51 citations
Semantic Scholar
Population Pharmacokinetics and Pharmacodynamics of Garenoxacin in Patients with Community-Acquired Respiratory Tract Infections
S. Van Wart, Luann Phillips, E. Ludwig, R. Russo +7 more
2004Antimicrobial Agents and Chemotherapy48 citations Open access
Semantic Scholar
Clinical and Economic Impact of Oral Ciprofloxacin as Follow-up to Parenteral Antibiotics
A. Hartzema, M. Porta, H. Tilson, T. Grasela +6 more
1991Drug Intelligence & Clinical Pharmacy44 citations
Semantic Scholar
An introduction to mixed effect modeling: Concepts, definitions, and justification
L. Sheiner, T. Grasela
199144 citations
Semantic Scholar
Implementation of a nursing home urinary incontinence management program with and without tolterodine.
J. Ouslander, C. Maloney, T. Grasela, Lucy Rogers +1 more
2001Journal of the American Medical Directors Association43 citations
Semantic Scholar
An introduction to mixed effect modeling: Concepts, definitions, and justification
L. Sheiner, T. Grasela
2005Journal of pharmacokinetics and biopharmaceutics39 citations
Semantic Scholar
Evaluation of hypothesis testing for comparing two populations using NONMEM analysis
D. B. White, C. Walawander, Dong Y. Liu, T. Grasela
1992Journal of pharmacokinetics and biopharmaceutics39 citations
Semantic Scholar
An evaluation of population pharmacokinetics in therapeutic trials. Part III. Prospective data collection versus retrospective data assembly
E. Antal, T. Grasela, Randall B. Smith
1989Clinical pharmacology and therapy38 citations
Semantic Scholar
Impact of Triplicate Prescription Program on Psychotropic Prescribing Patterns in Long-Term Care Facilities
A. Hartzema, M. Porta, H. Tilson, S. G. Zullich +3 more
1992The Annals of Pharmacotherapy32 citations
Semantic Scholar
An evaluation of point and interval estimates in population pharmacokinetics using Nonmem analysis
D. B. White, C. Walawander, Ying Tung, T. Grasela
1991Journal of pharmacokinetics and biopharmaceutics32 citations
Semantic Scholar
Capability of hospital computer systems in performing drug-use evaluations and adverse drug event monitoring.
T. Grasela, C. Walawander, Dianne L. Kennedy, H. Jolson
1993American journal of hospital pharmacy31 citations
Semantic Scholar
Model-Informed Drug Development for Malaria Therapeutics
K. Andrews, D. Wesche, J. McCarthy, Jörg J. Möhrle +4 more
2017Annual Review of Pharmacology and Toxicology29 citations Open access
Semantic Scholar
Pharmacostatistical modeling for observational data
T. Grasela, L. Sheiner
1991Journal of pharmacokinetics and biopharmaceutics29 citations
Semantic Scholar
The population pharmacokinetics of theophylline in neonates and young infants
E. S. Moore, R. Faix, R. Banagale, T. Grasela
1989Journal of pharmacokinetics and biopharmaceutics28 citations Open access
Semantic Scholar
Analysis of potential risk factors associated with the development of pancreatitis in phase I patients with AIDS or AIDS-related complex receiving didanosine.
T. Grasela, C. Walawander, Mohan Beltangady, Catherine A. Knupp +7 more
1994Journal of Infectious Diseases25 citations
Semantic Scholar
Population Pharmacokinetic Analysis of Didanosine (2′,3′‐Dideoxyinosine) Plasma Concentrations Obtained in Phase I Clinical Trials in Patients with AIDS or AIDS‐Related Complex
Sudhakar M. Pai, U. Shukla, T. Grasela, C. Knupp +7 more
1992Journal of clinical pharmacology25 citations
Semantic Scholar
A Nationwide Survey of Antibiotic Prescribing Patterns and Clinical Outcomes in Patients with Bacterial Pneumonia
T. Grasela, L. Welage, C. Walawander, Edward G. Timm +3 more
1990DICP : the annals of pharmacotherapy25 citations
Semantic Scholar
Evaluation of population pharmacokinetics in therapeutic trials. IV. Application to postmarketing surveillance
C. DeVane, T. Grasela, E. Antal, Ronald L. Miller
1993Clinical pharmacology and therapy24 citations
Semantic Scholar
A population pharmacokinetic‐pharmacodynamic analysis and model validation of azimilide
Luann Phillips, T. Grasela, Jeffrey R. Agnew, E. Ludwig +1 more
2001Clinical pharmacology and therapy23 citations
Semantic Scholar
An evaluation of the quinolone-theophylline interaction using the Food and Drug Administration spontaneous reporting system.
T. Grasela, Michael W. Dreis
1992Archives of Internal Medicine23 citations
Semantic Scholar
Prospective Surveillance of Antibiotic‐Associated Coagulopathy in 970 Patients
T. Grasela, C. Walawander, L. Welage, P. Wing +4 more
1989Pharmacotherapy23 citations
Semantic Scholar
Kinetics and action of N-methylthiotetrazole in volunteers and patients. Population-based clinical comparisons of antibiotics with and without this moiety.
Jerome J. Schentag, L. Welage, James S. Williams, J. Wilton +3 more
1988American Journal of Surgery22 citations
Semantic Scholar
Population pharmacokinetics of (R)-albuterol and (S)-albuterol in pediatric patients aged 4-11 years with asthma.
G. Maier, C. Rubino, R. Hsu, T. Grasela +1 more
2007Pulmonary Pharmacology & Therapeutics21 citations
Semantic Scholar
A32 BYPASSING THE PACU-A NEW PARADIGM IN AMBULATORY SURGERY
J. Apfelbaum, T. Grasela, C. Walawander
199719 citations
Semantic Scholar
Prospective Use of Population Pharmacokinetics/ Pharmacodynamics in the Development of Cisatracurium
V. Schmith, J. Fiedler-Kelly, Luann Phillips, T. Grasela
2004Pharmaceutical Research18 citations
Semantic Scholar
Exposure-response analyses of tigecycline tolerability in healthy subjects.
J. Passarell, E. Ludwig, K. Liolios, A. Meagher +3 more
2009Diagnostic microbiology and infectious disease14 citations
Semantic Scholar
An Automated Drug Concentration Screening and Quality Assurance Program for Clinical Trials
T. Grasela, E. Antal, J. Fiedler-Kelly, Darcy J. Foit +4 more
199913 citations
Semantic Scholar
A nationwide survey of clinical laboratory methodologies for fungal infections.
S. Goodwin, J. Fiedler-Kelly, T. Grasela, W. Schell +1 more
1992Journal of Medical and Veterinary Mycology13 citations
Semantic Scholar
Dose Proportionality of Cisatracurium
V. Schmith, J. Fiedler-Kelly, Luann Phillips, T. Grasela
1997Journal of clinical pharmacology11 citations
Semantic Scholar
The Cost-Effectiveness of Cefepime plus Metronidazole versus Imipenem/Cilastatin in the Treatment of Complicated Intra-Abdominal Infection
P. Barie, O. Rotstein, E. Dellinger, T. Grasela +1 more
2004Surgical Infections10 citations
Semantic Scholar

Frequent co-authors

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C. Walawander×16
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C. Walawander — researcher profile on SciRah
J. Fiedler-Kelly×7
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J. Fiedler-Kelly — researcher profile on SciRah
P. Ambrose×6
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P. Ambrose — researcher profile on SciRah
J. Apfelbaum×5
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J. Apfelbaum — researcher profile on SciRah

×5

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Luann Phillips — researcher profile on SciRah

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C. Mcleskey — researcher profile on SciRah

Jerome J. Schentag×4

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Jerome J. Schentag — researcher profile on SciRah

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E. Antal — researcher profile on SciRah

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M. Nahrwold — researcher profile on SciRah

T. H. Stanley×3

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T. H. Stanley — researcher profile on SciRah

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R. Thisted — researcher profile on SciRah

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D. Grasela — researcher profile on SciRah