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David G. McEwan · SciRah

Researcher profile · Semantic Scholar

David G. McEwan

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David G. McEwan — researcher profile on SciRah

h-index: 23
Works: 39
Citations: 7,532

Most-cited papers

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
P. Wild, H. Farhan, David G. McEwan, Sebastian A. Wagner +9 more
2011Science1,304 citations Open access
Semantic Scholar
Nix is a selective autophagy receptor for mitochondrial clearance
I. Novak, V. Kirkin, David G. McEwan, Ji Zhang +11 more
2010EMBO Reports1,297 citations Open access
Semantic Scholar
A role for ubiquitin in selective autophagy.
V. Kirkin, David G. McEwan, I. Novak, I. Dikič
2009Molecules and Cells1,265 citations Open access
Semantic Scholar
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.
V. Kirkin, T. Lamark, Y. Sou, G. Bjørkøy +14 more
2009Molecules and Cells1,199 citations Open access
Semantic Scholar
PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins.
David G. McEwan, Doris Popovic, A. Gubas, S. Terawaki +13 more
2015Molecules and Cells521 citations Open access
Semantic Scholar
The LC3 interactome at a glance
P. Wild, David G. McEwan, I. Dikič
2014Journal of Cell Science291 citations Open access
Semantic Scholar
Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling
E. Sandilands, B. Serrels, David G. McEwan, J. Morton +10 more
2011Nature Cell Biology180 citations
Semantic Scholar
Attenuation of the Activity of the cAMP-specific Phosphodiesterase PDE4A5 by Interaction with the Immunophilin XAP2*
G. Bolger, A. Peden, M. R. Steele, Carolynn Mackenzie +5 more
2003Journal of Biological Chemistry169 citations Open access
Semantic Scholar
Structural and functional analysis of the GABARAP interaction motif (GIM)
V. Rogov, Alexandra Stolz, Arvind C. Ravicahandran, Alexander Law +9 more
2016bioRxiv166 citations Open access
Semantic Scholar
The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation
David G. McEwan, I. Dikič
2011Trends in Cell Biology152 citations Open access
Semantic Scholar
Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors
E. Sandilands, Shiva Akbarzadeh, A. Vecchione, David G. McEwan +2 more
2007EMBO Reports111 citations Open access
Semantic Scholar
Atg8 family proteins, LIR/AIM motifs and other interaction modes
V. Rogov, Ioannis P. Nezis, Panagiotis Tsapras, Hong Zhang +13 more
2023Autophagy Reports97 citations Open access
Semantic Scholar
Structural basis for phosphorylation-triggered autophagic clearance of Salmonella.
V. Rogov, Hironori Suzuki, Evgenij Fiskin, P. Wild +10 more
2013Biochemical Journal97 citations
Semantic Scholar
PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection.
David G. McEwan, Benjamin Richter, Beatrice Claudi, C. Wigge +18 more
2015Cell Host and Microbe95 citations Open access
Semantic Scholar
Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy
Jake Cross, J. Durgan, David G. McEwan, Matthew Tayler +2 more
2023Journal of Cell Biology89 citations Open access
Semantic Scholar
Rab7a and Rab27b control secretion of endothelial microRNA through extracellular vesicles
Nicolas Jaé, David G. McEwan, Yosif Manavski, R. Boon +1 more
2015FEBS Letters85 citations Open access
Semantic Scholar
Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase.
David G. McEwan, V. Brunton, G. Baillie, N. Leslie +2 more
2007Cancer Research77 citations Open access
Semantic Scholar
Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation*
Sabrina Habisov, J. Huber, Y. Ichimura, M. Akutsu +9 more
2016Journal of Biological Chemistry74 citations Open access
Semantic Scholar
Host–pathogen interactions and subversion of autophagy
David G. McEwan
2017Essays in Biochemistry46 citations Open access
Semantic Scholar
PLEKHM1: Adapting to life at the lysosome
David G. McEwan, I. Dikič
2015Autophagy27 citations Open access
Semantic Scholar
ATG7 is a haploinsufficient repressor of tumor progression and promoter of metastasis
Jaclyn S. Long, E. Kania, David G. McEwan, V. Barthet +4 more
2022Proceedings of the National Academy of Sciences of the United States of America26 citations Open access
Semantic Scholar
ATG2 and VPS13 proteins: molecular highways transporting lipids to drive membrane expansion and organelle communication
David G. McEwan, K. Ryan
2021The FEBS Journal25 citations Open access
Semantic Scholar
Not all autophagy membranes are created equal.
David G. McEwan, I. Dikič
2010Cell24 citations Open access
Semantic Scholar
LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner
E. Kania, Jaclyn S. Long, David G. McEwan, K. Welkenhuyzen +8 more
2023Cell Death and Disease20 citations Open access
Semantic Scholar
Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis
Yixing Wu, Ying Bai, David G. McEwan, L. Bentley +2 more
2021Biology Open17 citations Open access
Semantic Scholar
Structural and functional analysis of the GABARAP interaction motif (GIM)
V. Rogov, Alexandra Stolz, A. Ravichandran, Diana O Rios-Szwed +8 more
2018EMBO Reports12 citations Open access
Semantic Scholar
Cullins keep autophagy under control.
David G. McEwan, I. Dikič
2014Developmental Cell12 citations Open access
Semantic Scholar
Impact of mesenchymal stromal cell–derived vesicular cargo on B-cell acute lymphoblastic leukemia progression
Christina Karantanou, Valentina R. Minciacchi, Rahul Kumar, C. Zanetti +14 more
2022Blood Advances10 citations Open access
Semantic Scholar
The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways
A. Gubas, Christina Karantanou, Doris Popovic, G. Tascher +6 more
2021FEBS Letters9 citations Open access
Semantic Scholar
A conserved ATG2‐GABARAP family interaction is critical for phagophore formation
Mihaela Božić, Luuk van den Bekerom, B. Milne, Nicola Goodman +5 more
2020EMBO Reports9 citations Open access
Semantic Scholar
DRAM‐4 and DRAM‐5 are compensatory regulators of autophagy and cell survival in nutrient‐deprived conditions
V. Barthet, M. Mrschtik, E. Kania, David G. McEwan +4 more
2022The FEBS Journal8 citations Open access
Semantic Scholar
A conserved ATG2-GABARAP interaction is critical for phagophore closure
Mihaela Božić, Luuk van den Bekerom, B. Milne, Nicola Goodman +5 more
2019bioRxiv6 citations Open access
Semantic Scholar
Species-specific cleavage of the autophagy adaptor p62 dictates responses to TNF.
Christoph Nössing, O. Troitskaya, Jaclyn S. Long, Andrew Craxton +13 more
2026Molecules and Cells4 citations Open access
Semantic Scholar
Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via CASM
Jake Cross, J. Durgan, David G. McEwan, O. Florey
2023bioRxiv4 citations Open access
Semantic Scholar
RUFY4 exists as two translationally regulated isoforms, that localize to the mitochondrion in activated macrophages
Jan Valecka, Voahirana Camosseto, David G. McEwan, S. Terawaki +8 more
2021Royal Society Open Science3 citations Open access
Semantic Scholar
kinesin recruitment by adapter SKIP on melanosomes is dynamically controlled by LC3B phosphorylation
Yogaspoorthi J. Subramaniam, Divya Murthy, Desingu Ayyappa Raja, Amrita Ramkumar +4 more
2021bioRxiv2 citations Open access
Semantic Scholar
Crystal structure of PLEKHM1 LIR-fused human LC3B_2-119
Hironori Suzuki, David G. McEwan, Doris Popovic, A. Gubas +13 more
20150 citations
Semantic Scholar
Autophagy receptors: Molecular basis of selective Autophagy
I. Dikič, V. Kirkin, I. Novak, David G. McEwan
20110 citations
Semantic Scholar
Cyclic AMP modulation and its effects on chemo-resistant colon cancer cell proliferation and survival
David G. McEwan
20080 citations
Semantic Scholar

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I. Dikič×22
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I. Dikič — researcher profile on SciRah
V. Rogov×7
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P. Wild×6
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V. Kirkin×5
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Hironori Suzuki

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S. Wakatsuki×5

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A. Gubas — researcher profile on SciRah