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V. Brunton · SciRah

Researcher profile · Semantic Scholar

V. Brunton

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V. Brunton — researcher profile on SciRah

h-index: 58
Works: 195
Citations: 15K

Most-cited papers

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
A. Krebs, J. Mitschke, M. L. Losada, O. Schmalhofer +12 more
2017Nature Cell Biology895 citations Open access
Semantic Scholar
E-cadherin–integrin crosstalk in cancer invasion and metastasis
M. Canel, A. Serrels, M. Frame, V. Brunton
2013Journal of Cell Science607 citations Open access
Semantic Scholar
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
M. Zimmermann, O. Murina, Martin A. M. Reijns, A. Agathanggelou +20 more
2018Nature373 citations Open access
Semantic Scholar
Nuclear FAK Controls Chemokine Transcription, Tregs, and Evasion of Anti-tumor Immunity
A. Serrels, T. Lund, B. Serrels, A. Byron +14 more
2015Cell368 citations Open access
Semantic Scholar
Integrin signalling regulates YAP and TAZ to control skin homeostasis
A. Elbediwy, Zoé I. Vincent-Mistiaen, B. Spencer-Dene, R. Stone +12 more
2016Development323 citations Open access
Semantic Scholar
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival.
A. Hamilton, G. Helgason, M. Schemionek, Bin Zhang +8 more
2012Blood264 citations Open access
Semantic Scholar
Mouse models of metastasis: progress and prospects
L. Gómez-Cuadrado, Natasha Tracey, Ruo-Yu Ma, Bin-Zhi Qian +1 more
2017Disease Models & Mechanisms260 citations Open access
Semantic Scholar
Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce interfollicular epidermal hyperplasia and tumor growth
V. Brunton, N. Barker, O. Sansom, V. Weaver
2013225 citations
Semantic Scholar
AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective.
S. H. Myers, V. Brunton, A. Unciti-Broceta
2015Journal of Medicinal Chemistry188 citations Open access
Semantic Scholar
The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype
P. Hari, F. Millar, Nuria Tarrats, J. Birch +10 more
2018Science Advances148 citations Open access
Semantic Scholar
Intravital FLIM-FRET imaging reveals dasatinib-induced spatial control of src in pancreatic cancer.
Max Nobis, E. McGhee, J. Morton, J. Schwarz +13 more
2013Cancer Research127 citations Open access
Semantic Scholar
CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer
J. Houthuijzen, Roebi de Bruijn, E. van der Burg, Anne Paulien Drenth +14 more
2022bioRxiv92 citations Open access
Semantic Scholar
ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival
Georgios Kanellos, Jing Zhou, Hitesh Patel, R. Ridgway +8 more
2015Cell Reports82 citations Open access
Semantic Scholar
Src kinase inhibitors: promising cancer therapeutics?
Helen Creedon, V. Brunton
2012Critical reviews in oncogenesis72 citations
Semantic Scholar
The fibrotic and immune microenvironments as targetable drivers of metastasis
L. Boulter, Esme Bullock, Zeanap Mabruk, V. Brunton
2020British Journal of Cancer70 citations Open access
Semantic Scholar
E-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer
K. Teo, L. Gómez-Cuadrado, M. Tenhagen, A. Byron +11 more
2018Scientific Reports68 citations Open access
Semantic Scholar
The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells
A. Serrels, K. McLeod, M. Canel, A. Kinnaird +3 more
2012International Journal of Cancer61 citations Open access
Semantic Scholar
Imaging drug uptake by bioorthogonal stimulated Raman scattering microscopy
William J. Tipping, Martin Lee, A. Serrels, V. Brunton +1 more
2017Chemical Science56 citations Open access
Semantic Scholar
Raman Imaging of Nanocarriers for Drug Delivery
Sally Vanden-Hehir, W. J. Tipping, Martin Lee, V. Brunton +2 more
2019Nanomaterials55 citations Open access
Semantic Scholar
The EMT-activator Zeb 1 is a key factor for cell plasticity and promotes metastasis in 1 pancreatic cancer 2
A. Krebs, J. Mitschke, M. L. Losada, O. Schmalhofer +14 more
201755 citations
Semantic Scholar
Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling.
G. H. Ashton, J. Morton, K. Myant, T. Phesse +15 more
2025Developmental Cell54 citations Open access
Semantic Scholar
Nuclear FAK and Runx1 cooperate to regulate IGFBP3, cell cycle progression and tumor growth
M. Canel, A. Byron, A. Sims, J. Cartier +5 more
2017Cancer Research53 citations Open access
Semantic Scholar
Utilizing Stimulated Raman Scattering Microscopy To Study Intracellular Distribution of Label-Free Ponatinib in Live Cells
Kristel Sepp, Martin Lee, Marie T. J. Bluntzer, G. Helgason +2 more
2019Journal of Medicinal Chemistry52 citations Open access
Semantic Scholar
Investigation of cellular uptake mechanism of functionalised gold nanoparticles into breast cancer using SERS
Anastasia Kapara, V. Brunton, D. Graham, K. Faulds
2020Chemical Science49 citations Open access
Semantic Scholar
WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel
Mara Artibani, A. Sims, J. Slight, Stuart Aitken +8 more
2017Scientific Reports48 citations Open access
Semantic Scholar
In vivo imaging of the tumor and its associated microenvironment using combined CARS / 2-photon microscopy
Martin Lee, A. Downes, You-Ying Chau, B. Serrels +5 more
2015IntraVital41 citations Open access
Semantic Scholar
ISGylation drives basal breast tumour progression by promoting EGFR recycling and Akt signalling
Alfonso Bolado-Carrancio, Martin Lee, Ailith Ewing, M. Muir +8 more
2019bioRxiv40 citations Open access
Semantic Scholar
MYC sensitises cells to apoptosis by driving energetic demand
Joy Edwards-Hicks, Hui-Zhong Su, M. Mangolini, K. K. Yoneten +29 more
2022Nature Communications39 citations Open access
Semantic Scholar
HO-1 drives autophagy as a mechanism of resistance against HER2-targeted therapies
Natasha Tracey, Helen Creedon, Alain J. Kemp, Jayne Culley +3 more
2019Breast Cancer Research and Treatment37 citations Open access
Semantic Scholar
Kindlin-1 regulates mitotic spindle formation by interacting with integrins and Plk-1
Hitesh Patel, Judith Zich, B. Serrels, C. Rickman +3 more
2013Nature Communications37 citations Open access
Semantic Scholar
Atlas of Lobular Breast Cancer Models: Challenges and Strategic Directions
George Sflomos, Koen Schipper, T. Koorman, A. Fitzpatrick +8 more
2021Cancers35 citations Open access
Semantic Scholar
A novel mode of inhibiting SRC improves drug efficacy and tolerability
Carolin Temps, D. Lietha, E. Webb, Xue-Feng Li +17 more
2021Cancer Research32 citations Open access
Semantic Scholar
Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence
I. Fernández-Duran, A. Quintanilla, Nuria Tarrats, J. Birch +8 more
2020Cell Death and Differentiation32 citations Open access
Semantic Scholar
N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture
Jason T. Weiss, Craig Fraser, B. Rubio-Ruiz, S. H. Myers +6 more
2014Frontiers in Chemistry31 citations Open access
Semantic Scholar
Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy
Helen Creedon, L. Gómez-Cuadrado, Zygimante Tarnauskaite, Jozef Balla +11 more
2016OncoTarget30 citations Open access
Semantic Scholar
Alkyne-Tagged PLGA Allows Direct Visualization of Nanoparticles In Vitro and Ex Vivo by Stimulated Raman Scattering Microscopy
Sally Vanden-Hehir, Stefan A. Cairns, Martin Lee, Lida Zoupi +4 more
2019Biomacromolecules29 citations Open access
Semantic Scholar
Kindlin1 regulates microtubule function to ensure normal mitosis
Hitesh Patel, Ifigeneia Stavrou, Roshan L. Shrestha, Viji M. Draviam +2 more
2016Journal of Molecular Cell Biology28 citations Open access
Semantic Scholar
Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells.
R. Ridgway, B. Serrels, S. Mason, A. Kinnaird +5 more
2012Carcinogenesis28 citations
Semantic Scholar
QD-filled micelles which combine SPECT and optical imaging with light-induced activation of a platinum(IV) prodrug for anticancer applications.
Carmen R. Maldonado, Nina Gómez-Blanco, M. Jauregui-Osoro, V. Brunton +2 more
2013Chemical Communications26 citations
Semantic Scholar
Diversity of Matriptase Expression Level and Function in Breast Cancer
A. Welman, D. Sproul, P. Mullen, M. Muir +5 more
2012PLoS ONE25 citations Open access
Semantic Scholar
Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion
S. Tollis, Andrea Rizzotto, N. Phạm, Sonja Koivukoski +14 more
2022ACS Chemical Biology24 citations Open access
Semantic Scholar
Kindlin-1 promotes pulmonary breast cancer metastasis
Sana Sarvi, Hitesh Patel, Jun Li, Georgia L Dodd +10 more
2018Cancer Research24 citations Open access
Semantic Scholar
Development of Potent Inhibitors of Receptor Tyrosine Kinases by Ligand-Based Drug Design and Target-Biased Phenotypic Screening
S. H. Myers, Carolin Temps, D. Houston, V. Brunton +1 more
2018Journal of Medicinal Chemistry23 citations Open access
Semantic Scholar
Characterisation of the Stromal Microenvironment in Lobular Breast Cancer
L. Gómez-Cuadrado, Esme Bullock, Zeanap Mabruk, Hong Zhao +12 more
2022Cancers22 citations Open access
Semantic Scholar
Kindlin‐1 protects cells from oxidative damage through activation of ERK signalling
H. Emmert, Hitesh Patel, V. Brunton
2017Free Radical Biology & Medicine22 citations Open access
Semantic Scholar
Novel roles of PRK1 and PRK2 in cilia and cancer biology
Hitesh Patel, Jun Li, A. Herrero, Jakob Kroboth +6 more
2020Scientific Reports21 citations Open access
Semantic Scholar
Selective tyrosine kinase inhibition of insulin‐like growth factor‐1 receptor inhibits human and mouse breast cancer–induced bone cell activity, bone remodeling, and osteolysis
John G. Logan, A. Sophocleous, S. Marino, M. Muir +2 more
2013Journal of Bone and Mineral Research21 citations Open access
Semantic Scholar
Combining imaging and pathway profiling: an alternative approach to cancer drug discovery.
N. Carragher, V. Brunton, M. Frame
2012Drug Discovery Today21 citations
Semantic Scholar
Exploring mechanisms of acquired resistance to HER2 (human epidermal growth factor receptor 2)-targeted therapies in breast cancer.
Helen Creedon, A. Byron, Joanna Main, L. Hayward +2 more
2014Biochemical Society Transactions20 citations
Semantic Scholar
The role and therapeutic potential of the autotaxin-lysophosphatidate signalling axis in breast cancer.
K. Teo, V. Brunton
2014Biochemical Journal20 citations
Semantic Scholar

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A. Byron×8
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Hitesh Patel — researcher profile on SciRah

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Martin Lee — researcher profile on SciRah

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L. Gómez-Cuadrado — researcher profile on SciRah