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L. Else · SciRah

Researcher profile · Semantic Scholar

L. Else

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L. Else — researcher profile on SciRah

h-index: 29
Works: 130
Citations: 2,462

Most-cited papers

A Compartmental Pharmacokinetic Evaluation of Long‐Acting Rilpivirine in HIV‐Negative Volunteers for Pre‐Exposure Prophylaxis
A. Jackson, L. Else, Pedro M. M. Mesquita, D. Egan +7 more
2014Clinical pharmacology and therapy106 citations
Semantic Scholar
Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: A randomised trial (DolPHIN-1 study)
C. Waitt, C. Orrell, S. Walimbwa, Yashna Singh +19 more
2019PLoS Medicine105 citations Open access
Semantic Scholar
Unintended Pregnancies Observed With Combined Use of the Levonorgestrel Contraceptive Implant and Efavirenz-based Antiretroviral Therapy: A Three-Arm Pharmacokinetic Evaluation Over 48 Weeks
K. Scarsi, Kristin M. Darin, S. Nakalema, D. Back +7 more
2015Clinical Infectious Diseases98 citations Open access
Semantic Scholar
Pharmacokinetic and Pharmacodynamic Comparison of Once‐Daily Efavirenz (400 mg vs. 600 mg) in Treatment‐Naïve HIV‐Infected Patients: Results of the ENCORE1 Study
L. Dickinson, J. Amin, L. Else, M. Boffito +12 more
2015Clinical pharmacology and therapy81 citations Open access
Semantic Scholar
Long-acting rilpivirine as potential pre-exposure prophylaxis for HIV-1 prevention (the MWRI-01 study): an open-label, phase 1, compartmental, pharmacokinetic and pharmacodynamic assessment.
I. McGowan, C. Dezzutti, A. Siegel, J. Engstrom +18 more
2016The Lancet HIV78 citations Open access
Semantic Scholar
The development and validation of a novel LC-MS/MS method for the simultaneous quantification of Molnupiravir and its metabolite ß-d-N4-hydroxycytidine in human plasma and saliva
A. Amara, S. D. Penchala, L. Else, C. Hale +5 more
2021Journal of Pharmaceutical and Biomedical Analysis70 citations Open access
Semantic Scholar
Is infant exposure to antiretroviral drugs during breastfeeding quantitatively important? A systematic review and meta-analysis of pharmacokinetic studies
C. Waitt, P. Garner, L. Bonnett, S. Khoo +1 more
2015Journal of Antimicrobial Chemotherapy57 citations Open access
Semantic Scholar
Comprehensive Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Evaluation of Once-Daily Efavirenz 400 and 600 mg in Treatment-Naïve HIV-Infected Patients at 96 Weeks: Results of the ENCORE1 Study
L. Dickinson, J. Amin, L. Else, M. Boffito +12 more
2015Clinical Pharmacokinetics55 citations Open access
Semantic Scholar
Discordant CSF/plasma HIV-1 RNA in patients with unexplained low-level viraemia
S. Nightingale, A. Geretti, A. Beloukas, M. Fisher +16 more
2016Journal of Neurovirology53 citations Open access
Semantic Scholar
Pharmacogenetics of pregnancy‐induced changes in efavirenz pharmacokinetics
A. Olagunju, O. Bolaji, A. Amara, L. Else +6 more
2015Clinical pharmacology and therapy51 citations
Semantic Scholar
Selection of Rilpivirine-Resistant HIV-1 in a Seroconverter From the SSAT 040 Trial Who Received the 300-mg Dose of Long-Acting Rilpivirine (TMC278LA).
Kerri J. Penrose, Urvi M. Parikh, Kristen A. Hamanishi, L. Else +4 more
2016Journal of Infectious Diseases45 citations
Semantic Scholar
Breast milk pharmacokinetics of efavirenz and breastfed infants’ exposure in genetically-defined subgroups of mother-infant pairs: an observational study
A. Olagunju, O. Bolaji, A. Amara, C. Waitt +6 more
2015Clinical Infectious Diseases41 citations Open access
Semantic Scholar
Development, validation and clinical application of a novel method for the quantification of efavirenz in dried breast milk spots using LC-MS/MS
A. Olagunju, O. Bolaji, A. Amara, C. Waitt +8 more
2014Journal of Antimicrobial Chemotherapy40 citations Open access
Semantic Scholar
Dolutegravir and elvitegravir plasma concentrations following cessation of drug intake.
Emilie R. Elliot, A. Amara, A. Jackson, G. Moyle +5 more
2016Journal of Antimicrobial Chemotherapy37 citations
Semantic Scholar
The importance of drug-drug interactions in the DAA era.
D. Back, L. Else
2013Digestive and Liver Disease36 citations Open access
Semantic Scholar
The development and application of a novel LC-MS/MS method for the measurement of Dolutegravir, Elvitegravir and Cobicistat in human plasma.
S. D. Penchala, S. Fawcett, L. Else, D. Egan +6 more
2016Journal of chromatography. B, Analytical technologies in the biomedical and life sciences34 citations
Semantic Scholar
Cerebrospinal fluid exposure of efavirenz and its major metabolites when dosed at 400 mg and 600 mg once daily: a randomized controlled trial.
A. Winston, J. Amin, A. Clarke, L. Else +10 more
2015Clinical Infectious Diseases33 citations Open access
Semantic Scholar
A Validated Method for Quantification of Efavirenz in Dried Blood Spots Using High-Performance Liquid Chromatography–Mass Spectrometry
A. Amara, L. Else, J. Tjia, A. Olagunju +3 more
2015Therapeutic Drug Monitoring32 citations
Semantic Scholar
Development, validation and clinical application of a method for the simultaneous quantification of lamivudine, emtricitabine and tenofovir in dried blood and dried breast milk spots using LC–MS/MS
C. Waitt, Sujan Diliiy Penchala, A. Olagunju, A. Amara +3 more
2017Journal of chromatography. B, Analytical technologies in the biomedical and life sciences31 citations Open access
Semantic Scholar
Brief Report: Pharmacokinetic/Pharmacodynamic Investigation of Single-Dose Oral Maraviroc in the Context of HIV-1 Pre-exposure Prophylaxis
J. Fox, J. Tiraboschi, C. Herrera, L. Else +8 more
2016Journal of Acquired Immune Deficiency Syndromes28 citations
Semantic Scholar
Infant Exposure to Dolutegravir Through Placental and Breast Milk Transfer: A Population Pharmacokinetic Analysis of DolPHIN-1
L. Dickinson, S. Walimbwa, Yashna Singh, J. Kaboggoza +21 more
2020Clinical Infectious Diseases27 citations Open access
Semantic Scholar
A Validated Method for Quantification of Dolutegravir Using Ultra Performance Liquid Chromatography Coupled With UV Detection
Xinzhu Wang, S. D. Penchala, A. Amara, L. Else +2 more
2016Therapeutic Drug Monitoring27 citations
Semantic Scholar
Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine
S. Walimbwa, M. Lamorde, C. Waitt, J. Kaboggoza +8 more
2018Antimicrobial Agents and Chemotherapy26 citations Open access
Semantic Scholar
An Open Label, Adaptive, Phase 1 Trial of High‐Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS‐CoV‐2
L. Walker, Richard J. Fitzgerald, G. Saunders, R. Lyon +29 more
2021medRxiv25 citations Open access
Semantic Scholar
Plasma Tenofovir, Emtricitabine, and Rilpivirine and Intracellular Tenofovir Diphosphate and Emtricitabine Triphosphate Pharmacokinetics following Drug Intake Cessation
L. Dickinson, H. Yapa, A. Jackson, G. Moyle +7 more
2015Antimicrobial Agents and Chemotherapy25 citations Open access
Semantic Scholar
Validation and clinical application of a method to quantify nevirapine in dried blood spots and dried breast milk spots
A. Olagunju, A. Amara, C. Waitt, L. Else +7 more
2015Journal of Antimicrobial Chemotherapy25 citations Open access
Semantic Scholar
Efavirenz and Metabolites in Cerebrospinal Fluid: Relationship with CYP2B6 c.516G→T Genotype and Perturbed Blood-Brain Barrier Due to Tuberculous Meningitis
S. Nightingale, C. Tran, M. Fisher, M. Nelson +11 more
2016Antimicrobial Agents and Chemotherapy23 citations Open access
Semantic Scholar
Evidence of HIV pre-exposure or post-exposure prophylaxis (PrEP/PEP) among blood donors: a pilot study, England June 2018 to July 2019
H. Harvala, C. Reynolds, Samreen Ijaz, V. Maddox +5 more
2021Sexually Transmitted Infections22 citations Open access
Semantic Scholar
Efavirenz- but not nevirapine-based antiretroviral therapy decreases exposure to the levonorgestrel released from a sub-dermal contraceptive implant
K. Scarsi, M. Lamorde, Kristin M. Darin, Sujan Dilly-Penchala +7 more
2014Journal of the International AIDS Society22 citations Open access
Semantic Scholar
Tenofovir Disoproxil Fumarate Fails to Prevent HIV Acquisition or the Establishment of a Viral Reservoir: Two Case Reports
J. Fox, M. Brady, H. Alexander, Olubanke Davies +8 more
2016Infectious Disease and Therapy21 citations Open access
Semantic Scholar
Pharmacokinetics of ß-d-N4-Hydroxycytidine, the Parent Nucleoside of Prodrug Molnupiravir, in Nonplasma Compartments of Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Richard J. Fitzgerald, L. Dickinson, L. Else, T. Fletcher +15 more
2022Clinical Infectious Diseases19 citations Open access
Semantic Scholar
Pharmacokinetic profile and safety of 150 mg of maraviroc dosed with 800/100 mg of darunavir/ritonavir all once daily, with and without nucleoside analogues, in HIV-infected subjects.
B. Mora-Peris, A. Croucher, L. Else, J. Vera +4 more
2013Journal of Antimicrobial Chemotherapy19 citations
Semantic Scholar
Single oral dose of maraviroc does not prevent ex-vivo HIV infection of rectal mucosa in HIV-1 negative human volunteers
J. Coll, J. Moltó, J. Boix, Elisabet Gómez-Mora +9 more
2015AIDS (London)18 citations Open access
Semantic Scholar
TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults)
Michael Abouyannis, Richard J. Fitzgerald, Mwanajuma Ngama, H. Mwangudzah +16 more
2022Wellcome Open Research17 citations Open access
Semantic Scholar
Genetic influence of ABCG2, UGT1A1 and NR1I2 on dolutegravir plasma pharmacokinetics.
Emilie R. Elliot, Megan Neary, L. Else, S. Khoo +6 more
2020Journal of Antimicrobial Chemotherapy17 citations
Semantic Scholar
Development and validation of an LC-MS/MS method for quantification of favipiravir in human plasma
E. Challenger, S. D. Penchala, C. Hale, Richard J. Fitzgerald +6 more
2023Journal of Pharmaceutical and Biomedical Analysis16 citations Open access
Semantic Scholar
Quantification of rilpivirine in human plasma, cervicovaginal fluid, rectal fluid and genital/rectal mucosal tissues using liquid chromatography-tandem mass spectrometry.
L. Else, J. Tjia, A. Jackson, S. D. Penchala +4 more
2014Bioanalysis16 citations
Semantic Scholar
Development, validation and utilization of a highly sensitive LC-MS/MS method for quantification of levonorgestrel released from a subdermal implant in human plasma
Lauren R. Cirrincione, S. D. Penchala, K. Scarsi, A. Podany +6 more
2018Journal of chromatography. B, Analytical technologies in the biomedical and life sciences15 citations Open access
Semantic Scholar
Pharmacokinetics of the co-administration of boceprevir and St John's wort to male and female healthy volunteers.
A. Jackson, A. D'Avolio, G. Moyle, S. Bonora +6 more
2014Journal of Antimicrobial Chemotherapy15 citations Open access
Semantic Scholar
Darunavir pharmacokinetics throughout pregnancy and postpartum
J. Lambert, V. Jackson, L. Else, M. Lawless +5 more
2014Journal of the International AIDS Society14 citations Open access
Semantic Scholar
Intrapulmonary pharmacokinetics of first-line anti-TB drugs in Malawian tuberculosis patients.
A. McCallum, Henry E Pertinez, L. Else, Sujan Dilly-Penchala +11 more
2020Clinical Infectious Diseases13 citations Open access
Semantic Scholar
A Multiple Dose Phase 1 Assessment of Rilpivirine Long Acting in a Model of Preexposure Prophylaxis Against HIV
Ross D. Cranston, C. Dezzutti, A. Siegel, J. Engstrom +13 more
2019AIDS Research and Human Retroviruses13 citations
Semantic Scholar
The pharmacokinetic profile of raltegravir-containing antiretroviral therapy in HIV-infected individuals over 60 years of age
J. Vera, A. Jackson, L. Dickinson, L. Else +5 more
2015HIV Clinical Trials13 citations Open access
Semantic Scholar
Undeclared pre-exposure or post-exposure prophylaxis (PrEP/PEP) use among syphilis-positive blood donors, England, 2020 to 2021
V. Maddox, C. Reynolds, A. Amara, L. Else +3 more
2023Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin12 citations Open access
Semantic Scholar
Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults
Michael Abouyannis, Yvonne K. Nyambura, Samson Ngome, D. Riako +17 more
2025EBioMedicine11 citations Open access
Semantic Scholar
Distinct Pharmacodynamic Activity of Rilpivirine in Ectocervical and Colonic Explant Tissue
C. Dezzutti, L. Else, Sarah E. Yandura, Cory Shetler +3 more
2016Antimicrobial Agents and Chemotherapy11 citations Open access
Semantic Scholar
Validation of an electrospray ionisation LC-MS/MS method for quantitative analysis of telaprevir and its R-diastereomer.
S. D. Penchala, J. Tjia, O. El Sherif, D. Back +2 more
2013Journal of chromatography. B, Analytical technologies in the biomedical and life sciences11 citations
Semantic Scholar
Pharmacokinetic/pharmacodynamic investigation of raltegravir with or without lamivudine in the context of HIV-1 pre-exposure prophylaxis (PrEP)
C. Herrera, J. Lwanga, Ming J. Lee, S. Mantori +10 more
2021Journal of Antimicrobial Chemotherapy10 citations Open access
Semantic Scholar
Steady-state pharmacokinetics of rilpivirine under different meal conditions in HIV-1-infected Ugandan adults.
M. Lamorde, S. Walimbwa, P. Byakika-Kibwika, M. Katwere +6 more
2015Journal of Antimicrobial Chemotherapy10 citations Open access
Semantic Scholar
Selection of Rilpivirine Resistant HIV-1 in a Seroconverter on Long-acting Rilpivirine (TMC278LA) from the Lowest Dose Arm of the SSAT 040 Trial
Kerri J. Penrose, Urvi M. Parikh, Kristen A. Hamanishi, Constantinos G. Panousis +5 more
201410 citations
Semantic Scholar

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