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Pedro M. M. Mesquita · SciRah

Researcher profile · Semantic Scholar

Pedro M. M. Mesquita

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Pedro M. M. Mesquita — researcher profile on SciRah

h-index: 23
Works: 37
Citations: 1,465

Most-cited papers

Disruption of Tight Junctions by Cellulose Sulfate Facilitates HIV Infection: Model of Microbicide Safety
Pedro M. M. Mesquita, N. Cheshenko, Sarah S. Wilson, M. Mhatre +4 more
2009Journal of Infectious Diseases116 citations Open access
Semantic Scholar
Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges
James M. Smith, Rachna Rastogi, Ryan S. Teller, P. Srinivasan +8 more
2013Proceedings of the National Academy of Sciences of the United States of America107 citations Open access
Semantic Scholar
A Compartmental Pharmacokinetic Evaluation of Long‐Acting Rilpivirine in HIV‐Negative Volunteers for Pre‐Exposure Prophylaxis
A. Jackson, L. Else, Pedro M. M. Mesquita, D. Egan +7 more
2014Clinical pharmacology and therapy106 citations
Semantic Scholar
Griffithsin Protects Mice from Genital Herpes by Preventing Cell-to-Cell Spread
Briana G. Nixon, M. Stefanidou, Pedro M. M. Mesquita, E. Fakioglu +5 more
2013Journal of Virology99 citations Open access
Semantic Scholar
Intravaginal ring delivery of tenofovir disoproxil fumarate for prevention of HIV and herpes simplex virus infection.
Pedro M. M. Mesquita, Rachna Rastogi, Theodore J. Segarra, Ryan S. Teller +4 more
2012Journal of Antimicrobial Chemotherapy87 citations Open access
Semantic Scholar
Herpes Simplex Virus Downregulates Secretory Leukocyte Protease Inhibitor: a Novel Immune Evasion Mechanism
E. Fakioglu, Sarah S. Wilson, Pedro M. M. Mesquita, Ehsan Hazrati +3 more
2008Journal of Virology87 citations Open access
Semantic Scholar
Bacterial Vaginosis and Subclinical Markers of Genital Tract Inflammation and Mucosal Immunity
A. Thurman, T. Kimble, B. Herold, Pedro M. M. Mesquita +9 more
2015AIDS Research and Human Retroviruses85 citations Open access
Semantic Scholar
A Randomized Trial to Assess Anti-HIV Activity in Female Genital Tract Secretions and Soluble Mucosal Immunity Following Application of 1% Tenofovir Gel
M. Keller, R. Madan, N. Torres, Melissa J. Fazzari +12 more
2011PLoS ONE83 citations Open access
Semantic Scholar
Candidate polyanion microbicides inhibit HIV-1 infection and dissemination pathways in human cervical explants
P. Fletcher, G. Wallace, Pedro M. M. Mesquita, R. Shattock
2006Retrovirology82 citations Open access
Semantic Scholar
Postcoital Bioavailability and Antiviral Activity of 0.5% PRO 2000 Gel: Implications for Future Microbicide Clinical Trials
M. Keller, Pedro M. M. Mesquita, N. Torres, Sylvia Cho +8 more
2010PLoS ONE62 citations Open access
Semantic Scholar
Vaginal microbiome modulates topical antiretroviral drug pharmacokinetics.
E. Taneva, Shada Sinclair, Pedro M. M. Mesquita, Brian Weinrick +8 more
2018JCI Insight47 citations Open access
Semantic Scholar
Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety
Sarah S. Wilson, N. Cheshenko, E. Fakioglu, Pedro M. M. Mesquita +2 more
2009Antiviral Therapy44 citations Open access
Semantic Scholar
Molecular Umbrellas: a Novel Class of Candidate Topical Microbicides To Prevent Human Immunodeficiency Virus and Herpes Simplex Virus Infections
R. Madan, Pedro M. M. Mesquita, N. Cheshenko, Bing-Wen Jing +7 more
2007Journal of Virology41 citations Open access
Semantic Scholar
Female Genital Tract Secretions and Semen Impact the Development of Microbicides for the Prevention of HIV and other Sexually Transmitted Infections
B. C. Herold, Pedro M. M. Mesquita, R. Madan, Marla J. Keller
2010American Journal of Reproductive Immunology38 citations Open access
Semantic Scholar
Differential Mechanisms of Tenofovir and Tenofovir Disoproxil Fumarate Cellular Transport and Implications for Topical Preexposure Prophylaxis
E. Taneva, Kerry Crooker, Sung Hyun Park, Jonathan T. Su +7 more
2015Antimicrobial Agents and Chemotherapy36 citations Open access
Semantic Scholar
Candidate Microbicide PPCM Blocks Human Immunodeficiency Virus Type 1 Infection in Cell and Tissue Cultures and Prevents Genital Herpes in a Murine Model
Pedro M. M. Mesquita, Sarah S. Wilson, P. Manlow, L. Fischetti +3 more
2008Journal of Virology36 citations Open access
Semantic Scholar
A Phase 1 Randomized Placebo-Controlled Safety and Pharmacokinetic Trial of a Tenofovir Disoproxil Fumarate Vaginal Ring
M. Keller, Pedro M. M. Mesquita, M. Marzinke, Ryan S. Teller +11 more
2016AIDS (London)32 citations Open access
Semantic Scholar
Comparison of Mucosal Markers of Human Immunodeficiency Virus Susceptibility in Healthy Premenopausal Versus Postmenopausal Women
A. Thurman, Nazita Yousefieh, Neelima Chandra, T. Kimble +13 more
2017AIDS Research and Human Retroviruses28 citations Open access
Semantic Scholar
Comparison of Follicular and Luteal Phase Mucosal Markers of HIV Susceptibility in Healthy Women
A. Thurman, Neelima Chandra, Nazita Yousefieh, I. Zalenskaya +10 more
2016AIDS Research and Human Retroviruses28 citations Open access
Semantic Scholar
Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data
S. Hughes, Claire N. Levy, R. Katz, E. Lokken +188 more
2022BMC Medicine27 citations Open access
Semantic Scholar
Bridging the Gap between Preclinical and Clinical Microbicide Trials: Blind Evaluation of Candidate Gels in Murine Models of Efficacy and Safety
Theodore J. Segarra, E. Fakioglu, N. Cheshenko, Sarah S. Wilson +3 more
2011PLoS ONE27 citations Open access
Semantic Scholar
Antiviral Activity of Genital Tract Secretions following Oral or Topical Tenofovir Pre-exposure Prophylaxis for HIV-1
B. Herold, C. Dezzutti, B. Richardson, J. Marrazzo +7 more
2014Journal of Acquired Immune Deficiency Syndromes26 citations Open access
Semantic Scholar
Pharmacokinetics and Safety Assessment of Anti-HIV Dapivirine Vaginal Microbicide Rings with Multiple Dosing
A. Nel, W. Haazen, Jeremy Nuttall, Joseph P. Romano +4 more
201425 citations Open access
Semantic Scholar
Osmotic pump tablets for delivery of antiretrovirals to the vaginal mucosa
Rachna Rastogi, Ryan S. Teller, Pedro M. M. Mesquita, B. Herold +1 more
2013Antiviral Research22 citations Open access
Semantic Scholar
Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary properties
Pedro M. M. Mesquita, P. Srinivasan, T. Johnson, Rachna Rastogi +7 more
2013Retrovirology20 citations Open access
Semantic Scholar
Role of Interleukin 32 in Human Immunodeficiency Virus Reactivation and Its Link to Human Immunodeficiency Virus–Herpes Simplex Virus Coinfection
Pedro M. M. Mesquita, P. Preston-Hurlburt, M. Keller, N. Vudattu +5 more
2016Journal of Infectious Diseases19 citations Open access
Semantic Scholar
Chronic HIV Infection Is Associated with Upregulation of Proinflammatory Cytokine and Chemokine and Alpha Defensin Gene Expression in Colorectal Mucosa
Jennifer Mait-Kaufman, E. Fakioglu, Pedro M. M. Mesquita, J. Elliott +2 more
2015AIDS Research and Human Retroviruses19 citations Open access
Semantic Scholar
Comparison of Mucosal Markers of HIV Susceptibility in Healthy Premenopausal versus Postmenopausal Women
A. Thurman, Nazita Yousefieh, Neelima Chandra, T. Kimble +16 more
201713 citations
Semantic Scholar
Pharmacokinetic and Pharmacodynamic Evaluation following Vaginal Application of IQB3002, a Dual-Chamber Microbicide Gel Containing the Nonnucleoside Reverse Transcriptase Inhibitor IQP-0528 in Rhesus Macaques
L. Pereira, Pedro M. M. Mesquita, A. Ham, Tyana Singletary +6 more
2015Antimicrobial Agents and Chemotherapy11 citations Open access
Semantic Scholar
A Perspective on Progress and Gaps in HIV Prevention Science
P. Kiser, Pedro M. M. Mesquita, B. Herold
2012AIDS Research and Human Retroviruses10 citations Open access
Semantic Scholar
Phase 1 Safety & Pharmacokinetic Trial of a Polyurethane Tenofovir Disoproxil Fumarate Intravaginal Ring in Healthy, Low-risk U.S. Women
Marla J. Keller, Lilia Espinoza, M. Marzinke, Pedro M. M. Mesquita +8 more
20141 citations
Semantic Scholar
Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary properties
Pedro M. M. Mesquita, P. Srinivasan, T. Johnson, Rachna Rastogi +7 more
2013Retrovirology1 citations Open access
Semantic Scholar
HIV transmission models: Lessons learned for microbicide formulation design
Pedro M. M. Mesquita, B. Herold
20140 citations
Semantic Scholar
Effect of Bacterial Vaginosis on Markers of Genital Tract Inflammation and Mucosal Immunity: Mechanisms for Susceptibility to HIV Infection
A. Thurman, Thomas D. Kimble, Tina D. Cunningham, Betsy C. Herold +8 more
20140 citations
Semantic Scholar
Use of the ICCA to Predict Dosing of HIV Microbicide Products to Achieve Virus Sterilization in Target Tissue
Karen W. Buckheit, Caitlin A. Buchholz, Cory Shetler, C. Dezzutti +3 more
20140 citations
Semantic Scholar
Mucosal Susceptibility to HIV-1 and Tenofovir Protection in Explanted Cervicovaginal Tissues from Postmenopausal Compared to Premenopausal Women
A. Thurman, Neelima Chandra, Nazita Yousefieh, Sharon M. Anderson +6 more
20140 citations Open access
Semantic Scholar
Vaginal washes from mice treated with cellulose sulfate 6% gel inhibit HSV-2 plaque formation.
Theodore J. Segarra, E. Fakioglu, N. Cheshenko, Sarah S. Wilson +3 more
20130 citations Open access
Semantic Scholar

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