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Megan Neary · SciRah

Researcher profile · Semantic Scholar

Megan Neary

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Megan Neary — researcher profile on SciRah

h-index: 15
Works: 45
Citations: 973

Most-cited papers

FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2
T. Brevini, M. Maes, G. Webb, Binu V. John +75 more
2022Nature262 citations Open access
Semantic Scholar
Prioritization of Anti‐SARS‐Cov‐2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics
Usman Arshad, H. Pertinez, H. Box, Lee M. Tatham +19 more
2020Clinical pharmacology and therapy136 citations Open access
Semantic Scholar
Rifampicin effect on intracellular and plasma pharmacokinetics of tenofovir alafenamide.
M. Cerrone, O. Alfarisi, Megan Neary, M. Marzinke +6 more
2019Journal of Antimicrobial Chemotherapy102 citations Open access
Semantic Scholar
The role of drug transporters in the kidney: lessons from tenofovir
D. Moss, Megan Neary, A. Owen
2014Frontiers in Pharmacology75 citations Open access
Semantic Scholar
Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis
R. K. R. Rajoli, H. Pertinez, Usman Arshad, H. Box +20 more
2020medRxiv42 citations Open access
Semantic Scholar
Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics of Efavirenz 400 mg Once Daily During Pregnancy and Post-Partum
M. Lamorde, Xinzhu Wang, Megan Neary, Elisa Bisdomini +7 more
2018Clinical Infectious Diseases31 citations Open access
Semantic Scholar
The Effect of Gene Variants on Levonorgestrel Pharmacokinetics when Combined with Antiretroviral Therapy containing Efavirenz or Nevirapine
Megan Neary, M. Lamorde, A. Olagunju, Kristin M. Darin +6 more
2017Clinical pharmacology and therapy31 citations Open access
Semantic Scholar
Dose prediction for repurposing nitazoxanide in SARS‐CoV‐2 treatment or chemoprophylaxis
Rajith K. R. Rajoli, H. Pertinez, Usman Arshad, H. Box +19 more
2020British Journal of Clinical Pharmacology28 citations Open access
Semantic Scholar
Pharmacokinetics of Efavirenz 400 mg Once Daily Coadministered With Isoniazid and Rifampicin in Human Immunodeficiency Virus–Infected Individuals
M. Cerrone, Xinzhu Wang, Megan Neary, C. Weaver +6 more
2018Clinical Infectious Diseases27 citations Open access
Semantic Scholar
Prioritisation of potential anti-SARS-CoV-2 drug repurposing opportunities based on ability to achieve adequate target site concentrations derived from their established human pharmacokinetics
Usman Arshad, H. Pertinez, H. Box, Lee M. Tatham +17 more
2020medRxiv23 citations Open access
Semantic Scholar
Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2
K. Gaynor, M. Vaysburd, Maximilian A. J. Harman, A. Albecka +28 more
2023Nature Communications20 citations Open access
Semantic Scholar
Meta-analysis of the effect of CYP2B6, CYP2A6, UGT2B7 and CAR polymorphisms on efavirenz plasma concentrations.
P. Ayuso, Megan Neary, J. Chiong, A. Owen
2019Journal of Antimicrobial Chemotherapy20 citations Open access
Semantic Scholar
Effect of patient genetics on etonogestrel pharmacokinetics when combined with efavirenz or nevirapine ART.
Megan Neary, C. Chappell, K. Scarsi, S. Nakalema +6 more
2019Journal of Antimicrobial Chemotherapy18 citations Open access
Semantic Scholar
Genetic influence of ABCG2, UGT1A1 and NR1I2 on dolutegravir plasma pharmacokinetics.
Emilie R. Elliot, Megan Neary, L. Else, S. Khoo +6 more
2020Journal of Antimicrobial Chemotherapy17 citations
Semantic Scholar
Pregnancy affects nevirapine pharmacokinetics: evidence from a CYP2B6 genotype-guided observational study
A. Olagunju, O. Bolaji, Megan Neary, D. Back +2 more
2016Pharmacogenetics & Genomics16 citations
Semantic Scholar
Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case
Lee M. Tatham, A. Kipar, Joanne Sharp, Edyta Kijak +13 more
2022bioRxiv11 citations Open access
Semantic Scholar
Pharmacogenetic considerations for HIV treatment in different ethnicities: an update
Megan Neary, Andrew Owen
2017Expert Opinion on Drug Metabolism & Toxicology11 citations
Semantic Scholar
Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters
Megan Neary, Joanne Sharp, Eduardo Gallardo-Toledo, Joanne Herriott +17 more
2023Viruses9 citations Open access
Semantic Scholar
Evaluation of intranasal nafamostat or camostat for SARS-CoV-2 chemoprophylaxis in Syrian golden hamsters
Megan Neary, H. Box, Joanne Sharp, Lee M. Tatham +14 more
2021bioRxiv9 citations Open access
Semantic Scholar
Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection.
James J. Hobson, A. Savage, A. Dwyer, Catherine Unsworth +15 more
2021Nanoscale8 citations Open access
Semantic Scholar
Naturally-acquired immunity in Syrian Golden Hamsters provides protection from re-exposure to emerging heterosubtypic SARS-CoV-2 variants B.1.1.7 and B.1.351
J. Clark, Parul Sharma, E. Bentley, Adam C. Harding +13 more
2021bioRxiv8 citations Open access
Semantic Scholar
Development of a highly sensitive bioanalytical assay for the quantification of favipiravir.
P. Curley, Megan Neary, Usman Arshad, Lee M. Tatham +7 more
2021bioRxiv8 citations Open access
Semantic Scholar
Impact of pharmacogenetics and pregnancy on tenofovir and emtricitabine pharmacokinetics.
J. Gini, A. Olagunju, L. Dickinson, C. Waitt +4 more
2019Pharmacogenomics (London)8 citations
Semantic Scholar
Linear and branched polymer prodrugs of the water-soluble nucleoside reverse-transcriptase inhibitor emtricitabine as structural materials for long-acting implants
Anika Shakil, F. Hern, Chung-Jun Liu, Kartik W Temburnikar +7 more
2022Journal of materials chemistry. B6 citations Open access
Semantic Scholar
A Lower Dose of Efavirenz Can Be Coadministered With Rifampicin and Isoniazid in Tuberculosis Patients
J. Kaboggoza, Xin-Xia Wang, Megan Neary, P. Ayuso +6 more
2019Open Forum Infectious Diseases6 citations Open access
Semantic Scholar
Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations
P. Curley, James J. Hobson, N. Liptrott, E. Makarov +13 more
2023Pharmaceutics5 citations Open access
Semantic Scholar
Do genetic variations in proximal tubule transporters influence tenofovir-induced renal dysfunction? An exploratory study in a Ghanaian population.
Megan Neary, A. Olagunju, F. Sarfo, R. Phillips +3 more
2020Journal of Antimicrobial Chemotherapy5 citations
Semantic Scholar
Assessment of Favipiravir and Remdesivir in Combination for SARS-CoV-2 Infection in Syrian Golden Hamsters
Megan Neary, Eduardo Gallardo-Toledo, Joanne Sharp, Joanne Herriott +17 more
2024Viruses4 citations Open access
Semantic Scholar
Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters
H. Box, Joanne Sharp, S. Pennington, Edyta Kijak +21 more
2023Journal of Antimicrobial Chemotherapy4 citations Open access
Semantic Scholar
Chemoprophylactic Assessment of Combined Intranasal SARS-CoV-2 Polymerase and Exonuclease Inhibition in Syrian Golden Hamsters
Eduardo Gallardo-Toledo, Megan Neary, Joanne Sharp, Joanne Herriott +12 more
2023Viruses3 citations Open access
Semantic Scholar
Lack of antiviral activity of probenecid in Vero E6 cells and Syrian golden hamsters: a need for better understanding of inter-lab differences in preclinical assays
H. Box, S. Pennington, Edyta Kijak, Lee M. Tatham +15 more
2022bioRxiv3 citations Open access
Semantic Scholar
Optimisation and validation of a sensitive bioanalytical method for niclosamide
Usman Arshad, H. Pertinez, H. Box, Lee M. Tatham +12 more
2021bioRxiv3 citations Open access
Semantic Scholar
Hyaluronidase impacts exposures of long-acting injectable paliperidone palmitate in rodent models
H. Pertinez, Amit Kaushik, P. Curley, Usman Arshad +12 more
2024bioRxiv2 citations Open access
Semantic Scholar
Relating CYP2B6 genotype and efavirenz resistance among post-partum women living with HIV with high viremia in Uganda: a nested cross-sectional study
Allan Buzibye, K. Wools-Kaloustian, A. Olagunju, E. Twinomuhwezi +10 more
2023AIDS Research and Therapy2 citations Open access
Semantic Scholar
Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.
Megan Neary, Usman Arshad, Lee M. Tatham, H. Pertinez +8 more
2023Journal of chromatography. B, Analytical technologies in the biomedical and life sciences2 citations Open access
Semantic Scholar
Lack of Ronapreve (REGN-CoV; casirivimab and imdevimab) virological efficacy against the SARS-CoV 2 Omicron variant (B.1.1.529) in K18-hACE2 mice
Lee M. Tatham, Joanne Sharp, Edyta Kijak, Joanne Herriott +11 more
20222 citations
Semantic Scholar
Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.
Megan Neary, Usman Arshad, Lee M. Tatham, H. Pertinez +8 more
2021bioRxiv2 citations Open access
Semantic Scholar
Pharmacokinetics of HIV therapies in pregnant patients: an update
Megan Neary, A. Owen, A. Olagunju
2020Expert Opinion on Drug Metabolism & Toxicology2 citations
Semantic Scholar
Clinical, pharmacological, and qualitative characterization of drug-drug interactions in pregnant women initiating HIV therapy in Sub-Saharan Africa.
D. Kiiza, Danial Rostami-Hochaghan, Y. Alhassan, K. Seden +20 more
2024Journal of Antimicrobial Chemotherapy1 citations
Semantic Scholar
Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case
Lee M. Tatham, A. Kipar, Joanne Sharp, Edyta Kijak +13 more
2024Microbiology spectrum1 citations Open access
Semantic Scholar
Polymer–prodrug conjugates as candidates for degradable, long-acting implants, releasing the water-soluble nucleoside reverse-transcriptase inhibitor emtricitabine
C. Liu, F. Hern, Anika Shakil, Kartik W Temburnikar +8 more
2023Journal of materials chemistry. B1 citations Open access
Semantic Scholar
Breaking down barriers: A funder's perspective on achieving equity and inclusivity in infectious disease modelling and epidemiology.
Sumithra Subramaniam, Katherine Davis, C. Mukandavire, Sophie Demellweek +7 more
2026Epidemics0 citations Open access
Semantic Scholar
A Holistic Review of the Preclinical Landscape for Long-Acting Anti-infective Drugs Using HIV as a Paradigm.
Megan Neary, A. Owen, A. Olagunju
2022Clinical Infectious Diseases0 citations Open access
Semantic Scholar
Relating CYP2B6 Genotype and EFV Resistance Among Women Living With HIV With High Viremia in Uganda: A Nested Cross-Sectional Study.
Allan Buzibye, K. Wools-Kaloustian, A. Olagunju, E. Twinomuhwezi +10 more
20210 citations Open access
Semantic Scholar
Assessment of the inter-individual variation observed between patients receiving HIV antiretroviral therapy
Megan Neary
20180 citations
Semantic Scholar

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