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D. Oyen · SciRah

Researcher profile · Semantic Scholar

D. Oyen

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D. Oyen — researcher profile on SciRah

h-index: 18
Works: 56
Citations: 1,368

Most-cited papers

A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine
Nicholas C. Wu, Seth J. Zost, A. Thompson, D. Oyen +5 more
2017PLoS Pathogens227 citations Open access
Semantic Scholar
Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization
M. Bianchi, H. Turner, B. Nogal, C. Cottrell +9 more
2018Immunity208 citations Open access
Semantic Scholar
A public antibody lineage that potently inhibits malaria infection by dual binding to the circumsporozoite protein
Joshua Tan, B. Sack, D. Oyen, Isabelle Zenklusen +17 more
2018Nature Medicine185 citations Open access
Semantic Scholar
Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein
D. Oyen, J. Torres, U. Wille-Reece, C. Ockenhouse +8 more
2017Proceedings of the National Academy of Sciences of the United States of America143 citations Open access
Semantic Scholar
Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts
D. Oyen, J. Torres, C. Cottrell, C. King +2 more
2018Science Advances82 citations Open access
Semantic Scholar
Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates
C. Cottrell, Jelle van Schooten, C. Bowman, M. Yuan +27 more
2020bioRxiv81 citations Open access
Semantic Scholar
Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway
D. Oyen, R. B. Fenwick, R. Stanfield, H. Dyson +1 more
2015Journal of the American Chemical Society47 citations Open access
Semantic Scholar
Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein
D. Oyen, J. Torres, P. Aoto, Yevel Flores-Garcia +15 more
2020PLoS Pathogens38 citations Open access
Semantic Scholar
Functional human IgA targets a conserved site on malaria sporozoites
Joshua Tan, Hyeseong Cho, T. Pholcharee, Lais S. Pereira +28 more
2021Science Translational Medicine37 citations Open access
Semantic Scholar
A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum
N. Beutler, T. Pholcharee, D. Oyen, Yevel Flores-Garcia +18 more
2022PLoS Pathogens35 citations Open access
Semantic Scholar
Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihydrofolate reductase of Escherichia coli.
D. Oyen, R. Wechselberger, V. Srinivasan, J. Steyaert +1 more
2013Biochimica et Biophysica Acta35 citations Open access
Semantic Scholar
Constraining enzyme conformational change by an antibody leads to hyperbolic inhibition.
D. Oyen, V. Srinivasan, J. Steyaert, J. Barlow
2011Journal of Molecular Biology35 citations
Semantic Scholar
Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein
T. Pholcharee, D. Oyen, J. Torres, Yevel Flores-Garcia +9 more
2019Journal of Molecular Biology33 citations Open access
Semantic Scholar
Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection
G. M. Martin, J. Torres, T. Pholcharee, D. Oyen +15 more
2023Nature Communications30 citations Open access
Semantic Scholar
A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity
E. Thai, G. Costa, Anna M. Weyrich, R. Murugan +12 more
2020bioRxiv30 citations Open access
Semantic Scholar
Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion
D. Oyen, R. B. Fenwick, P. Aoto, R. L. Stanfield +3 more
2017Journal of the American Chemical Society30 citations Open access
Semantic Scholar
Slow dynamics of tryptophan-water networks in proteins
R. B. Fenwick, D. Oyen, H. Dyson, Peter E. Wright
2018Journal of the American Chemical Society26 citations Open access
Semantic Scholar
Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex
Wei-Feng Liu, Z. Maben, Carole Wang, Kevin C. Lindquist +12 more
2021Journal of Biological Chemistry22 citations Open access
Semantic Scholar
An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity that Reverses Carfentanil-Induced Respiratory Depression
L. M. Eubanks, T. Pholcharee, D. Oyen, Y. Natori +3 more
2023bioRxiv17 citations Open access
Semantic Scholar
Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts
D. Oyen, J. Torres, C. Cottrell, C. King +2 more
2018bioRxiv9 citations Open access
Semantic Scholar
Multi-probe Relaxation Dispersion Measurements Increase Sensitivity to Protein Dynamics
R. B. Fenwick, D. Oyen, Peter E. Wright
2016Physical Chemistry, Chemical Physics - PCCP7 citations Open access
Semantic Scholar
Modeling of hidden structures using sparse chemical shift data from NMR relaxation dispersion.
R. B. Fenwick, D. Oyen, H. van den Bedem, H. Dyson +1 more
2020Biophysical Journal5 citations Open access
Semantic Scholar
Correction for Oyen et al., Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein
D. Oyen, J. Torres, U. Wille-Reece, C. Ockenhouse +8 more
2018Proceedings of the National Academy of Sciences of the United States of America4 citations Open access
Semantic Scholar
Affinity-matured homotypic interactions induce spectrum of PfCSP-antibody structures that influence protection from malaria infection
G. M. Martin, J. Torres, T. Pholcharee, D. Oyen +15 more
2022bioRxiv2 citations Open access
Semantic Scholar
Inhibition of ligand exchange kinetics via active-site trapping with an antibody fragment.
D. Oyen, J. Steyaert, J. Barlow
2014Biochemistry2 citations Open access
Semantic Scholar
Crystal structure of macaque anti-HIV-1 antibody RM20F
D. Oyen, M. Yuan, I. Grant Wilson
20200 citations
Semantic Scholar
Crystal structure of Fab395 in complex with NPNA2 peptide from circumsporozoite protein
T. Pholcharee, D. Oyen, I. Grant Wilson
20200 citations
Semantic Scholar
Crystal structure of Fab356 in complex with NPNA2 peptide from circumsporozoite protein
T. Pholcharee, D. Oyen, I. Grant Wilson
20200 citations
Semantic Scholar
Crystal structure of Fab667 complex
D. Oyen, Ian A. Wilson
20200 citations
Semantic Scholar
Crystal structure of Fab366 in complex with NPNA3 peptide from circumsporozoite protein
T. Pholcharee, D. Oyen, I. Grant Wilson
20200 citations
Semantic Scholar
Crystal structure of Fab399 in complex with NPNA3 peptide from circumsporozoite protein
T. Pholcharee, D. Oyen, I. Grant Wilson
20200 citations
Semantic Scholar
Fab397 in complex with NPNA peptide
T. Pholcharee, D. Oyen, I. Grant Wilson
20200 citations
Semantic Scholar
Crystal structure of Fab239 in complex with NPNA2 peptide from circumsporozoite protein
T. Pholcharee, D. Oyen, I. Grant Wilson
20200 citations
Semantic Scholar
Crystal structure of Fab239 in complex with NPNA4 peptide from circumsporozoite protein
T. Pholcharee, D. Oyen, I. Grant Wilson
20200 citations
Semantic Scholar
Crystal structure of Fab399 in complex with NPNA6 peptide from circumsporozoite protein
T. Pholcharee, D. Oyen, I. Grant Wilson
20200 citations
Semantic Scholar
Crystal structure of Fab364 in complex with NPNA2 peptide from circumsporozoite protein
T. Pholcharee, D. Oyen, I. Grant Wilson
20200 citations
Semantic Scholar
Crystal structure of Fab224 in complex with NPNA4 peptide from circumsporozoite protein
T. Pholcharee, D. Oyen, I. Grant Wilson
20200 citations
Semantic Scholar
Crystal structure of Fab668 complex
D. Oyen, Ian A. Wilson
20200 citations
Semantic Scholar
HIV Env BG505 SOSIP with polyclonal Fabs from immunized rabbit #3417 post-boost#1
H. Turner, C. Cottrell, D. Oyen, I. Grant Wilson +1 more
20180 citations
Semantic Scholar
Anti HIV Fab 10A
Lars Hangartner, A. B. Ward, Ian A. Wilson, D. Oyen
20180 citations
Semantic Scholar
Backbone 1H, 13C and 15N chemical shift assignments for the ternary L28F ecDHFR:TETRAHYDROFOLATE:NADP+ complex
P. Wright, J. Dyson, R. Stanfield, Bryn Fenwick +1 more
20180 citations
Semantic Scholar
Backbone 1H, 13C and 15N chemical shift assignments for the binary L28F ecDHFR:NADPH complex
P. Wright, J. Dyson, R. Stanfield, Bryn Fenwick +1 more
20180 citations
Semantic Scholar
MGG4 Fab in complex with peptide
D. Oyen, Joshua Tan, A. Lanzavecchia, I. Grant Wilson
20180 citations
Semantic Scholar
A structural explanation for the low efficacy of the seasonal influenza H3N2 vaccine
Nicholas C. Wu, A. Thompson, D. Oyen, Corwin M. Nycholat +3 more
20170 citations Open access
Semantic Scholar
L28F E.coli DHFR in complex with NADPH
D. Oyen, P. Wright, I. Grant Wilson
20170 citations
Semantic Scholar
Crystal structure of Fab317 complex
D. Oyen, Ian A. Wilson
20170 citations
Semantic Scholar
Crystal structure of Fab311 complex
D. Oyen, I. Grant Wilson
20170 citations
Semantic Scholar
wild-type E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate
D. Oyen, P. Wright
20150 citations
Semantic Scholar
Nanobody ca1697 binding to the DHFR.folate binary complex
D. Oyen, J. Steyaert, J. Barlow
20130 citations
Semantic Scholar
R104A-ca1697 nanobody binding to the binary DHFR.folate complex
D. Oyen, J. Steyaert, J. Barlow
20130 citations
Semantic Scholar

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I. Grant Wilson×25
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I. Grant Wilson — researcher profile on SciRah
T. Pholcharee×18
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T. Pholcharee — researcher profile on SciRah
J. Torres×9
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C. King×9
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Yevel Flores-Garcia

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Daniel E. Emerling×7

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Ian A. Wilson×6

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