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P. Aoto · SciRah

Researcher profile · Semantic Scholar

P. Aoto

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P. Aoto — researcher profile on SciRah

h-index: 13
Works: 29
Citations: 416

Most-cited papers

Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2
Sven H. Schmidt, J. Weng, P. Aoto, D. Boassa +8 more
2020Proceedings of the National Academy of Sciences of the United States of America52 citations Open access
Semantic Scholar
Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome.
Adrián Palencia-Campos, P. Aoto, E. M. Machal, A. Rivera-Barahona +38 more
2020American Journal of Human Genetics49 citations Open access
Semantic Scholar
Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP
Tsan-Wen Lu, Jian Wu, P. Aoto, J. Weng +5 more
2019Proceedings of the National Academy of Sciences of the United States of America39 citations Open access
Semantic Scholar
Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein
D. Oyen, J. Torres, P. Aoto, Yevel Flores-Garcia +15 more
2020PLoS Pathogens38 citations Open access
Semantic Scholar
Dynamic allostery-based molecular workings of kinase:peptide complexes
Lalima G. Ahuja, P. Aoto, A. Kornev, G. Veglia +1 more
2019Proceedings of the National Academy of Sciences of the United States of America38 citations Open access
Semantic Scholar
Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion
D. Oyen, R. B. Fenwick, P. Aoto, R. L. Stanfield +3 more
2017Journal of the American Chemical Society30 citations Open access
Semantic Scholar
LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains
J. Weng, P. Aoto, R. Lorenz, Jian Wu +9 more
2022PLoS Biology23 citations Open access
Semantic Scholar
Calculation of centralities in protein kinase A
A. Kornev, P. Aoto, Susan S. Taylor
2022bioRxiv23 citations Open access
Semantic Scholar
NMR Characterization of Information Flow and Allosteric Communities in the MAP Kinase p38γ
P. Aoto, B. Martin, P. Wright
2016Scientific Reports21 citations Open access
Semantic Scholar
Structural analyses of the PKA RIIβ holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma
Tsan-Wen Lu, P. Aoto, J. Weng, C. Nielsen +6 more
2020PLoS Biology20 citations Open access
Semantic Scholar
Kinase Domain Is a Dynamic Hub for Driving LRRK2 Allostery
Susan S. Taylor, Pallavi Kaila-Sharma, J. Weng, P. Aoto +4 more
2020Frontiers in Molecular Neuroscience18 citations Open access
Semantic Scholar
Biarsenical-tetracysteine motif as a fluorescent tag for detection in capillary electrophoresis.
S. Kottegoda, P. Aoto, C. Sims, N. Allbritton
2008Analytical Chemistry16 citations Open access
Semantic Scholar
Probing the Non-Native H Helix Translocation in Apomyoglobin Folding Intermediates
P. Aoto, Chiaki Nishimura, H. Dyson, P. Wright
2014Biochemistry15 citations Open access
Semantic Scholar
Molecular-dynamics simulation methods for macromolecular crystallography
David C. Wych, P. Aoto, Lily Vu, A. Wolff +4 more
2022bioRxiv12 citations Open access
Semantic Scholar
A dynamic switch in inactive p38γ leads to an excited state on pathway to an active kinase
P. Aoto, R. Stanfield, I. Grant Wilson, H. Dyson +1 more
2019Biochemistry10 citations Open access
Semantic Scholar
Two PKA RI alpha holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP
Tsan-Wen Lu, Jian Wu, P. Aoto, J. Weng +5 more
20195 citations
Semantic Scholar
X-ray diffraction analysis of a crystal of HscA from Escherichia coli.
P. Aoto, D. Ta, J. Cupp-Vickery, L. Vickery
2005Acta Crystallographica. Section F : Structural Biology and Crystallization Communications4 citations Open access
Semantic Scholar
Correction: LRRK2 dynamics analysis identifies allosteric control of the crosstalk between its catalytic domains
Jui-Hung Weng, P. Aoto, R. Lorenz, Jian Wu +10 more
2025PLoS Biology1 citations
Semantic Scholar
Two helices control the dynamic crosstalk between the catalytic domains of LRRK2
J. Weng, P. Aoto, R. Lorenz, Jian Wu +7 more
2021bioRxiv1 citations Open access
Semantic Scholar
PKA RIα Holoenzyme Crystal Structure Reveals Its Allosteric Regulation and Carney Complex Disease Implications
Tsan-Wen Lu, Jian Wu, Lalima G. Ahuja, P. Aoto +2 more
20181 citations
Semantic Scholar
Correction for Schmidt et al., Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2
Sven H. Schmidt, Jui-Hung Weng, P. Aoto, Daniela Boassa +9 more
2025Proceedings of the National Academy of Sciences of the United States of America0 citations Open access
Semantic Scholar
PKA RIα Holoenzyme Structure Reveals ATP‐Dependent Dynamics and Allosteric Regulation in Isoform‐Specific Manner
Tsan-Wen Lu, Jian Wu, P. Aoto, J. Weng +3 more
2020The FASEB Journal0 citations Open access
Semantic Scholar
PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
Tsan-Wen Lu, P. Aoto, J. Weng, C. Nielsen +6 more
20200 citations
Semantic Scholar
Functional and Structural Characterization of Acrodysostosis Mutations of PKA RIα Reveals Mechanism Causing resistant to cAMP activation
J. D. Del Rio, Leon L. Wu, Tsan-Wen Lu, P. Aoto +1 more
2020The FASEB Journal0 citations Open access
Semantic Scholar
Protein Kinase A isoform dynamics and disease.
P. Aoto, Blaine Baker, Susan S. Taylor
2020The FASEB Journal0 citations Open access
Semantic Scholar
Dynamic Disease Landscape of a Cancer Driving Fusion Kinase
P. Aoto, Susan S. Taylor
20200 citations Open access
Semantic Scholar
Structural and Dynamic Effects of Phosphorylation of Protein Kinase a Catalytic Subunit
Lily Vu, Susan S. Taylor, P. Aoto, J. Weng
20200 citations Open access
Semantic Scholar
Backbone 1H, 13C, and 15N Chemical Shift Assignments for MAPK p38g
P. Aoto, P. Wright
20160 citations
Semantic Scholar
1P086 Non-native H helix translocation in folding intermediate of apomyoglobin(01F. Protein : Engineering,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))
Chiaki Nishimura, P. Aoto, J. Dyson, P. Wright
20140 citations Open access
Semantic Scholar

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