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Y. Kusakari · SciRah

Researcher profile · Semantic Scholar

Y. Kusakari

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Y. Kusakari — researcher profile on SciRah

h-index: 22
Works: 80
Citations: 1,807

Most-cited papers

p38α Mitogen-Activated Protein Kinase Plays a Critical Role in Cardiomyocyte Survival but Not in Cardiac Hypertrophic Growth in Response to Pressure Overload
K. Nishida, Osamu Yamaguchi, Shinichi Hirotani, S. Hikoso +20 more
2004Molecular and Cellular Biology242 citations Open access
Semantic Scholar
Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling
Osamu Yamaguchi, Y. Higuchi, Shinichi Hirotani, K. Kashiwase +15 more
2003Proceedings of the National Academy of Sciences of the United States of America236 citations Open access
Semantic Scholar
Cardiac mTOR protects the heart against ischemia-reperfusion injury.
Toshinori Aoyagi, Y. Kusakari, Chunyang Xiao, Brendan T. Inouye +5 more
2012American Journal of Physiology. Heart and Circulatory Physiology141 citations Open access
Semantic Scholar
mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy.
Xiaoxia Song, Y. Kusakari, Chunyang Xiao, S. Kinsella +5 more
2010American Journal of Physiology - Cell Physiology139 citations Open access
Semantic Scholar
Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice.
M. Asahi, K. Otsu, Hiroyuki Nakayama, S. Hikoso +15 more
2004Proceedings of the National Academy of Sciences of the United States of America121 citations Open access
Semantic Scholar
Posttranslational modifications of mitochondrial fission and fusion proteins in cardiac physiology and pathophysiology.
Stephanie M. Adaniya, O-Uchi Jin, M. Cypress, Y. Kusakari +1 more
2019American Journal of Physiology - Cell Physiology110 citations Open access
Semantic Scholar
Interaction of &agr;1-Adrenoceptor Subtypes With Different G Proteins Induces Opposite Effects on Cardiac L-type Ca2+ Channel
O-Uchi Jin, Hiroyuki Sasaki, S. Morimoto, Y. Kusakari +5 more
2008Circulation Research71 citations Open access
Semantic Scholar
Cardiac‐specific overexpression of a high Ca2+ affinity mutant of SERCA2a attenuates in vivo pressure overload cardiac hypertrophy
Hiroyuki Nakayama, K. Otsu, Osamu Yamaguchi, K. Nishida +11 more
2003The FASEB Journal70 citations
Semantic Scholar
α1-Adrenoceptor stimulation potentiates L-type Ca2+ current through Ca2+/calmodulin-dependent PK II (CaMKII) activation in rat ventricular myocytes
O-Uchi Jin, K. Komukai, Y. Kusakari, T. Obata +3 more
200559 citations Open access
Semantic Scholar
Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling
Toshihiro Takeda, M. Asahi, Osamu Yamaguchi, S. Hikoso +17 more
2005The FASEB Journal48 citations
Semantic Scholar
p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload.
K. Nishida, O. Yamaguchi, Shinichi Hirotani, S. Hikoso +20 more
2004Molecular and Cellular Biology46 citations
Semantic Scholar
Fibrosis growth factor 23 is a promoting factor for cardiac fibrosis in the presence of transforming growth factor-β1
Kazuhiro Kuga, Y. Kusakari, Ken Uesugi, K. Semba +3 more
2020PLoS ONE38 citations Open access
Semantic Scholar
Comparative Effects of Bupivacaine and Ropivacaine on Intracellular Calcium Transients and Tension in Ferret Ventricular Muscle
Y. Mio, N. Fukuda, Y. Kusakari, Y. Amaki +2 more
2004Anesthesiology34 citations
Semantic Scholar
Bupivacaine Attenuates Contractility by Decreasing Sensitivity of Myofilaments to Ca2+, in Rat Ventricular Muscle
Y. Mio, N. Fukuda, Y. Kusakari, Y. Tanifuji +1 more
2002Anesthesiology34 citations
Semantic Scholar
alpha1-adrenoceptor stimulation potentiates L-type Ca2+ current through Ca2+/calmodulin-dependent PK II (CaMKII) activation in rat ventricular myocytes.
O-Uchi Jin, K. Komukai, Y. Kusakari, T. Obata +3 more
2005Proceedings of the National Academy of Sciences of the United States of America33 citations
Semantic Scholar
Depressed Frank-Starling mechanism in the left ventricular muscle of the knock-in mouse model of dilated cardiomyopathy with troponin T deletion mutation ΔK210.
Takahiro Inoue, F. Kobirumaki-Shimozawa, Tatsuya Kagemoto, Teruyuki Fujii +7 more
2013Journal of Molecular and Cellular Cardiology30 citations
Semantic Scholar
Protein kinase A-dependent phosphorylation of ryanodine receptors increases Ca2+ leak in mouse heart.
S. Morimoto, O-Uchi Jin, M. Kawai, Toshiyuki Hoshina +5 more
2009Biochemical and Biophysical Research Communications - BBRC30 citations
Semantic Scholar
Role of Mitochondrial Ca2+ Homeostasis in Cardiac Muscles
Jessica L. Cao, Stephanie M. Adaniya, M. Cypress, Yuta Suzuki +3 more
2019Archives of Biochemistry and Biophysics29 citations Open access
Semantic Scholar
Mitogen-Activated Protein Kinase Plays a Critical Role in Cardiomyocyte Survival but Not in Cardiac Hypertrophic Growth in Response to Pressure Overload
K. Nishida, Osamu Yamaguchi, Shinichi Hirotani, S. Hikoso +20 more
200428 citations
Semantic Scholar
New mouse model of skeletal muscle atrophy using spiral wire immobilization
Akiko Onda, H. Kono, Qi-Bin Jiao, T. Akimoto +6 more
2016Muscle and Nerve27 citations
Semantic Scholar
The effects of heat stress on morphological properties and intracellular signaling of denervated and intact soleus muscles in rats
T. Ohira, A. Higashibata, M. Seki, Yoichi Kurata +8 more
2017Physiological Reports23 citations Open access
Semantic Scholar
Pulmonary hypertension due to left heart disease causes intrapulmonary venous arterialization in rats
Yoshitaka Fujimoto, T. Urashima, F. Kawachi, Toru Akaike +3 more
2017Journal of Thoracic and Cardiovascular Surgery22 citations Open access
Semantic Scholar
Thiamine treatment preserves cardiac function against ischemia injury via maintaining mitochondrial size and ATP levels.
Yuki Yamada, Y. Kusakari, Munetoshi Akaoka, M. Watanabe +6 more
2020Journal of applied physiology20 citations
Semantic Scholar
Impairment of Excitation-Contraction Coupling in Right Ventricular Hypertrophied Muscle with Fibrosis Induced by Pulmonary Artery Banding
Y. Kusakari, T. Urashima, D. Shimura, Erika Amemiya +6 more
2017PLoS ONE20 citations Open access
Semantic Scholar
Intracellular mechanism of the negative inotropic effect induced by alpha1-adrenoceptor stimulation in mouse myocardium.
Shuta Hirano, Y. Kusakari, O-Uchi Jin, S. Morimoto +3 more
2006Journal of Physiological Sciences18 citations Open access
Semantic Scholar
Low Cardiac Output Leads Hepatic Fibrosis in Right Heart Failure Model Rats
Yoshitaka Fujimoto, T. Urashima, D. Shimura, Reiji Ito +9 more
2016PLoS ONE16 citations Open access
Semantic Scholar
Presenilin 2 regulates the systolic function of heart by modulating Ca[2+] signaling
Toshihiro Takeda, M. Asahi, Osamu Yamaguchi, S. Hikoso +17 more
200615 citations
Semantic Scholar
Estimation of myofibrillar responsiveness to Ca2+ in isolated rat ventricular myocytes
K. Hongo, Y. Kusakari, M. Konishi, S. Kurihara +1 more
1998Pflügers Archiv13 citations
Semantic Scholar
Tissue thrombin is associated with the pathogenesis of dilated cardiomyopathy.
Keiichi Ito, K. Hongo, T. Date, M. Ikegami +23 more
2017International Journal of Cardiology12 citations
Semantic Scholar
Heterozygous deletion of sarcolipin maintains normal cardiac function.
D. Shimura, Y. Kusakari, T. Sasano, Yasuhiro Nakashima +8 more
2016American Journal of Physiology. Heart and Circulatory Physiology11 citations Open access
Semantic Scholar
Myocyte injury along myofibers in left ventricular remodeling after myocardial infarction
Y. Kusakari, Chunyang Xiao, N. Himes, S. Kinsella +3 more
2009Interactive Cardiovascular and Thoracic Surgery11 citations Open access
Semantic Scholar
The mechanism of increasing Ca2+ responsiveness by alpha1-adrenoceptor stimulation in rat ventricular myocytes.
Y. Kusakari, K. Hongo, M. Kawai, M. Konishi +1 more
2002The Japanese Journal of Physiology10 citations Open access
Semantic Scholar
Superior logistic model for decay of Ca2+ transient and isometric relaxation force curve in rabbit and mouse papillary muscles.
J. Mizuno, M. Otsuji, K. Takeda, Yoshitsugu Yamada +5 more
2007International Heart Journal9 citations Open access
Semantic Scholar
Use of the Ca-shortening curve to estimate the myofilament responsiveness to Ca2+ in tetanized rat ventricular myocytes.
Y. Kusakari, K. Hongo, M. Kawai, M. Konishi +1 more
2006Journal of Physiological Sciences9 citations Open access
Semantic Scholar
Use of tetanus to investigate myofibrillar responsiveness to Ca(2+) in isolated mouse ventricular myocytes.
K. Hongo, Y. Kusakari, M. Kawai, M. Konishi +2 more
2002The Japanese Journal of Physiology9 citations Open access
Semantic Scholar
Pyruvate dehydrogenase activation precedes the down-regulation of fatty acid oxidation in monocrotaline-induced myocardial toxicity in mice
Gaku Nakai, D. Shimura, Ken Uesugi, Ichige Kajimura +5 more
2018Heart and Vessels8 citations
Semantic Scholar
Genetic modulation of the SERCA activity does not affect the Ca(2+) leak from the cardiac sarcoplasmic reticulum.
S. Morimoto, K. Hongo, Y. Kusakari, K. Komukai +7 more
2014Cell Calcium7 citations
Semantic Scholar
Half-logistic time constants as inotropic and lusitropic indices for four sequential phases of isometric tension curves in isolated rabbit and mouse papillary muscles.
J. Mizuno, S. Morita, M. Otsuji, H. Arita +5 more
2009International Heart Journal6 citations Open access
Semantic Scholar
Three‐dimensional myocardial scarring along myofibers after coronary ischemia–reperfusion revealed by computerized images of histological assays
M. Katz, Y. Kusakari, H. Aoyagi, Jason K. Higa +7 more
2014Physiological Reports5 citations Open access
Semantic Scholar
Alpha1-adrenenoceptor stimulation inhibits cardiac excitation–contraction coupling through tyrosine phosphorylation of beta1-adrenoceptor
O-Uchi Jin, K. Komukai, Y. Kusakari, S. Morimoto +6 more
2013Biochemical and Biophysical Research Communications - BBRC5 citations Open access
Semantic Scholar
Characterization of intracellular Ca2+ transient by the hybrid logistic function in aequorin-injected rabbit and mouse papillary muscles.
J. Mizuno, M. Otsuji, H. Arita, K. Hanaoka +5 more
2007Journal of Physiological Sciences4 citations Open access
Semantic Scholar
c-Src-dependent phosphorylation of Mfn2 regulates endoplasmic reticulum-mitochondria tethering
Peng Zhang, Kara A. Ford, J. H. Sung, Yuta Suzuki +15 more
2022bioRxiv2 citations Open access
Semantic Scholar
Distinct Vascular Remodeling Pattern of Adult Rats with Carotid-Jugular Shunt.
P. Lu, Qi-Bin Jiao, D. Shimura, Y. Kusakari +2 more
2018Annals of Vascular Surgery1 citations
Semantic Scholar
[Novel assessment of intracellular calcium transient decay in cardiac muscle by curve-fitting with half-logistic function].
J. Mizuno, H. Arita, K. Hanaoka, Y. Kusakari +1 more
2008Masui. The Japanese journal of anesthesiology1 citations
Semantic Scholar
PKC is involved in the negative inotropic effect of α_1-adrenoceptor stimulation in mouse myocardium
Shuta Hirano, Y. Kusakari, O-Uchi Jin, K. Komukai +3 more
20041 citations
Semantic Scholar
Spread of Ca2+ in the sarcomere during fast and slow activation of mammalian cardiac myocytes.
M. Konishi, Y. Kusakari, K. Hongo, Satoshi Kurihara
2001Canadian Journal of Physiology and Pharmacology1 citations
Semantic Scholar
Effects of microgravity on gastric glandular histology
Hiroki Bochimoto, Daisuke Kondoh, Kaoru Tobe, Kentaro Takeda +13 more
2026Acta Astronautica0 citations
Semantic Scholar
Abstract 861: Inner Mitochondrial Collapsing in Response to Acute Overstretch of Rat Ventricular Papillary Muscles
Naritomo Nishioka, Y. Kusakari, J. Tanihata, S. Minamisawa
2019Circulation Research0 citations
Semantic Scholar
Abstract 12265: Downregulation of Endoplasmic Reticulum- Mitochondria Tethering Proteins in Monocrotaline-Induced Pulmonary Arterial Hypertension
Shunsuke Baba, Satoko Shinjo, M. Okada, Yoshitaka Fujimoto +3 more
20180 citations
Semantic Scholar
Diastolic overstretch causes inner mitochondrial collapsing and impaired force generation in isolated rat papillary muscle
S. Minamisawa, Naritomo Nishioka, F. Usui, Y. Kusakari
20180 citations
Semantic Scholar

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S. Kurihara×24
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S. Kurihara — researcher profile on SciRah
K. Hongo×23
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S. Minamisawa×15
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O-Uchi Jin×11
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O-Uchi Jin — researcher profile on SciRah

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M. Kawai — researcher profile on SciRah

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K. Otsu — researcher profile on SciRah

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Toshihiro Takeda×8

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Toshihiro Takeda — researcher profile on SciRah

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K. Nishida — researcher profile on SciRah

Osamu Yamaguchi×7

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Osamu Yamaguchi — researcher profile on SciRah

K. Kashiwase×7

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K. Kashiwase — researcher profile on SciRah

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K. Komukai — researcher profile on SciRah