Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Toshihiro Takeda · SciRah

Researcher profile · Semantic Scholar

Toshihiro Takeda

Share profile

Toshihiro Takeda — researcher profile on SciRah

h-index: 33
Works: 138
Citations: 6,487

Most-cited papers

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
Atsuko Nakai, Osamu Yamaguchi, Toshihiro Takeda, Y. Higuchi +10 more
2007Nature Medicine1,526 citations
Semantic Scholar
Mitochondrial DNA That Escapes from Autophagy Causes Inflammation and Heart Failure
T. Oka, S. Hikoso, Osamu Yamaguchi, Manabu Taneike +10 more
2012Nature1,215 citations Open access
Semantic Scholar
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
Tomokazu Murakawa, Osamu Yamaguchi, Ayako Hashimoto, S. Hikoso +16 more
2015Nature Communications451 citations Open access
Semantic Scholar
Inhibition of autophagy in the heart induces age-related cardiomyopathy
Manabu Taneike, Osamu Yamaguchi, Atsuko Nakai, S. Hikoso +13 more
2010Autophagy427 citations Open access
Semantic Scholar
Activation of TGF-β1-TAK1-p38 MAPK pathway in spared cardiomyocytes is involved in left ventricular remodeling after myocardial infarction in rats
Madoka Matsumoto-Ida, Yoshihito Takimoto, T. Aoyama, M. Akao +2 more
2006113 citations
Semantic Scholar
Inhibition of phospholamban phosphorylation by O-GlcNAcylation: implications for diabetic cardiomyopathy.
Shunichi Yokoe, M. Asahi, Toshihiro Takeda, K. Otsu +3 more
2010Glycobiology100 citations Open access
Semantic Scholar
Real-Time 2-Photon Imaging of Mitochondrial Function in Perfused Rat Hearts Subjected to Ischemia/Reperfusion
Madoka Matsumoto-Ida, M. Akao, Toshihiro Takeda, Masashi Kato +1 more
2006Circulation91 citations Open access
Semantic Scholar
The Antioxidant Edaravone Attenuates Pressure Overload–Induced Left Ventricular Hypertrophy
I. Tsujimoto, S. Hikoso, Osamu Yamaguchi, K. Kashiwase +9 more
2005HYPERTENSION75 citations
Semantic Scholar
Apoptosis Signal-Regulating Kinase 1/p38 Signaling Pathway Negatively Regulates Physiological Hypertrophy
M. Taniike, Osamu Yamaguchi, I. Tsujimoto, S. Hikoso +11 more
2008Circulation67 citations Open access
Semantic Scholar
CaMKII activates ASK1 and NF-κB to induce cardiomyocyte hypertrophy
K. Kashiwase, Y. Higuchi, Shinichi Hirotani, Osamu Yamaguchi +11 more
200567 citations
Semantic Scholar
Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes.
S. Omiya, S. Hikoso, Y. Imanishi, Atsuhiro Saito +11 more
2008Journal of Molecular and Cellular Cardiology66 citations
Semantic Scholar
The I&kgr;B Kinase β/Nuclear Factor &kgr;B Signaling Pathway Protects the Heart From Hemodynamic Stress Mediated by the Regulation of Manganese Superoxide Dismutase Expression
S. Hikoso, Osamu Yamaguchi, Yuko Nakano, Toshihiro Takeda +13 more
2009Circulation Research63 citations Open access
Semantic Scholar
Apoptosis signal-regulating kinase 1 is involved not only in apoptosis but also in non-apoptotic cardiomyocyte death.
Tetsuya Watanabe, K. Otsu, Toshihiro Takeda, Osamu Yamaguchi +9 more
2005Biochemical and Biophysical Research Communications - BBRC61 citations
Semantic Scholar
Calpain Protects the Heart from Hemodynamic Stress*
Manabu Taneike, Isamu Mizote, T. Morita, Tetsuya Watanabe +13 more
2011Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Rheb (Ras Homologue Enriched in Brain)-dependent Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation Becomes Indispensable for Cardiac Hypertrophic Growth after Early Postnatal Period*
Takahito Tamai, Osamu Yamaguchi, S. Hikoso, Toshihiro Takeda +13 more
2013Journal of Biological Chemistry53 citations Open access
Semantic Scholar
Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading.
Jota Oyabu, Osamu Yamaguchi, S. Hikoso, Toshihiro Takeda +10 more
2013Biochemical and Biophysical Research Communications - BBRC51 citations
Semantic Scholar
Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling
Toshihiro Takeda, M. Asahi, Osamu Yamaguchi, S. Hikoso +17 more
2005The FASEB Journal48 citations
Semantic Scholar
Study protocol for the PURSUIT-HFpEF study: a Prospective, Multicenter, Observational Study of Patients with Heart Failure with Preserved Ejection Fraction
Shinichiro Suna, S. Hikoso, T. Yamada, M. Uematsu +15 more
2020BMJ Open43 citations Open access
Semantic Scholar
Extracting clinical terms from radiology reports with deep learning
Kento Sugimoto, Toshihiro Takeda, Jong-Hoon Oh, Shoya Wada +7 more
2021Journal of Biomedical Informatics41 citations Open access
Semantic Scholar
Progression of heart failure was suppressed by inhibition of apoptosis signal-regulating kinase 1 via transcoronary gene transfer.
S. Hikoso, Y. Ikeda, Osamu Yamaguchi, Toshihiro Takeda +10 more
2007Journal of the American College of Cardiology41 citations Open access
Semantic Scholar
The targeting of cyclophilin D by RNAi as a novel cardioprotective therapy: evidence from two-photon imaging.
Masashi Kato, M. Akao, Madoka Matsumoto-Ida, T. Makiyama +4 more
2009Cardiovascular Research37 citations
Semantic Scholar
Reduction in hemoglobin-oxygen affinity results in the improvement of exercise capacity in mice with chronic heart failure.
Tetsuya Watanabe, Toshihiro Takeda, S. Omiya, S. Hikoso +15 more
2008Journal of the American College of Cardiology37 citations Open access
Semantic Scholar
Activation of TGF-beta1-TAK1-p38 MAPK pathway in spared cardiomyocytes is involved in left ventricular remodeling after myocardial infarction in rats.
Madoka Matsumoto-Ida, Yoshihito Takimoto, T. Aoyama, M. Akao +2 more
2006American Journal of Physiology. Heart and Circulatory Physiology37 citations
Semantic Scholar
Long‐Term Outcomes and Clinical Predictors of Mortality Following Occurrence of Stent Thrombosis
T. Ishihara, K. Okada, H. Kida, T. Tsujimura +44 more
2022Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease31 citations Open access
Semantic Scholar
CaMKII activates ASK1 and NF-kappaB to induce cardiomyocyte hypertrophy.
K. Kashiwase, Y. Higuchi, Shinichi Hirotani, Osamu Yamaguchi +11 more
2005Biochemical and Biophysical Research Communications - BBRC30 citations
Semantic Scholar
The efficacy and safety of left atrial low‐voltage area guided ablation for recurrence prevention compared to pulmonary vein isolation alone in patients with persistent atrial fibrillation trial: Design and rationale
A. Sunaga, M. Masuda, Koichi Inoue, N. Tanaka +22 more
2021Clinical Cardiology28 citations Open access
Semantic Scholar
Serofendic acid, a novel substance extracted from fetal calf serum, protects against oxidative stress in neonatal rat cardiac myocytes.
Toshihiro Takeda, M. Akao, Madoka Matsumoto-Ida, Masashi Kato +5 more
2006Journal of the American College of Cardiology28 citations Open access
Semantic Scholar
A Pre-Training Technique to Localize Medical BERT and to Enhance Biomedical BERT
Shoya Wada, Toshihiro Takeda, Shiro Manabe, Shozo Konishi +2 more
202024 citations Open access
Semantic Scholar
Oversampling effect in pretraining for bidirectional encoder representations from transformers (BERT) to localize medical BERT and enhance biomedical BERT
Shoya Wada, Toshihiro Takeda, Katsuki Okada, Shiro Manabe +3 more
2020Artif. Intell. Medicine24 citations Open access
Semantic Scholar
Identification of mild cognitive impairment subtypes predicting conversion to Alzheimer’s disease using multimodal data
M. Kikuchi, Kaori Kobayashi, Sakiko Itoh, K. Kasuga +11 more
2022Computational and Structural Biotechnology Journal20 citations Open access
Semantic Scholar
The practice of active patient involvement in rare disease research using ICT: experiences and lessons from the RUDY JAPAN project
Nao Hamakawa, Atsushi Kogetsu, Moeko Isono, Chisato Yamasaki +16 more
2021Research Involvement and Engagement18 citations Open access
Semantic Scholar
Case Report Form Reporter: A Key Component for the Integration of Electronic Medical Records and the Electronic Data Capture System
Y. Matsumura, Atsushi Hattori, Shiro Manabe, Daiyo Takahashi +5 more
2017Medinfo18 citations
Semantic Scholar
Effect of Extensive Ablation on Recurrence in Patients with Persistent Atrial Fibrillation Treated with Pulmonary Vein Isolation (EARNEST-PVI) trial: Design and rationale.
T. Dohi, D. Nakatani, Koichi Inoue, S. Hikoso +21 more
2019Journal of Cardiology17 citations Open access
Semantic Scholar
Corrigendum: Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
T. Oka, S. Hikoso, Osamu Yamaguchi, Manabu Taneike +10 more
2012Nature17 citations Open access
Semantic Scholar
Direct monitoring of mitochondrial calcium levels in cultured cardiac myocytes using a novel fluorescent indicator protein, GCaMP2-mt.
M. Iguchi, Masashi Kato, J. Nakai, Toshihiro Takeda +4 more
2012International Journal of Cardiology16 citations Open access
Semantic Scholar
Presenilin 2 regulates the systolic function of heart by modulating Ca[2+] signaling
Toshihiro Takeda, M. Asahi, Osamu Yamaguchi, S. Hikoso +17 more
200615 citations
Semantic Scholar
Interconnection of Electronic Medical Record with Clinical Data Management System by CDISC ODM
Y. Matsumura, Atsushi Hattori, Shiro Manabe, Toshihiro Takeda +4 more
2014Medical Informatics Europe13 citations
Semantic Scholar
Automatic creation of annotations for chest radiographs based on the positional information extracted from radiographic image reports
Bowen Wang, Toshihiro Takeda, Kento Sugimoto, Jiahao Zhang +5 more
2021Comput. Methods Programs Biomed.12 citations Open access
Semantic Scholar
Post-discharge changes in nutritional status predict prognosis in patients with acute decompensated HFpEF from the PURSUIT-HFpEF Registry
Takashi Kitao, S. Hikoso, S. Tamaki, M. Seo +68 more
2024Heart and Vessels9 citations Open access
Semantic Scholar
Outcomes for Atrial Fibrillation Patients with Silent Left Atrial Thrombi Detected by Transesophageal Echocardiography.
Koichi Inoue, Shinichiro Suna, K. Iwakura, T. Oka +29 more
2017American Journal of Cardiology9 citations
Semantic Scholar
Activation of MTK1/MEKK4 induces cardiomyocyte death and heart failure.
Isamu Mizote, Osamu Yamaguchi, S. Hikoso, Toshihiro Takeda +9 more
2010Journal of Molecular and Cellular Cardiology9 citations
Semantic Scholar
Impact of stroke on survival in patients with cancer.
Y. Gon, Tsutomu Sasaki, Tomohiro Kawano, S. Okazaki +4 more
2023Thrombosis Research8 citations
Semantic Scholar
Screening of anticancer drugs to detect drug‐induced interstitial pneumonia using the accumulated data in the electronic medical record
Yoshie Shimai, Toshihiro Takeda, K. Okada, Shiro Manabe +3 more
2018Pharmacology Research & Perspectives7 citations Open access
Semantic Scholar
Evaluation of Secure Computation in a Distributed Healthcare Setting
E. Kimura, Koki Hamada, Ryo Kikuchi, Koji Chida +6 more
2016Medical Informatics Europe7 citations Open access
Semantic Scholar
Serofendic acid, a substance extracted from fetal calf serum, as a novel drug for cardioprotection.
M. Akao, Toshihiro Takeda, T. Kita, T. Kume +1 more
2007Cardiovascular Drug Reviews7 citations Open access
Semantic Scholar
Practical use of a multicenter clinical research support system connected to electronic medical records
Shiro Manabe, Toshihiro Takeda, Atsushi Hattori, Masashi Yamamoto +6 more
2021Comput. Methods Programs Biomed.6 citations
Semantic Scholar
Estimating the Ratio of Patients with a Certain Disease Between Hospitals for the Allocation of Patients to Clinical Trials Using Health Insurance Claims Data in Japan
Toshihiro Takeda, Naoki Mihara, T. Murata, Yoshie Shimai +3 more
2016Medical Informatics Europe4 citations
Semantic Scholar
Process Approach for Managing Health Information System-Induced Medication Errors
M. Yusof, Toshihiro Takeda, Naoki Mihara, Y. Matsumura
2020Medical Informatics Europe3 citations Open access
Semantic Scholar
A Strategy for Reusing the Data of Electronic Medical Record Systems for Clinical Research
Y. Matsumura, Atsushi Hattori, Shiro Manabe, Tsutomu Tsuda +4 more
2016Medical Informatics Europe3 citations
Semantic Scholar
End-to-End Approach for Structuring Radiology Reports
Kento Sugimoto, Toshihiro Takeda, Shoya Wada, Asuka Yamahata +3 more
2020Medical Informatics Europe2 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

S. Hikoso×26
Invite
S. Hikoso — researcher profile on SciRah
Y. Matsumura×26
Invite
Y. Matsumura — researcher profile on SciRah
K. Otsu×21
Invite
K. Otsu — researcher profile on SciRah
Osamu Yamaguchi×20
Invite
Osamu Yamaguchi — researcher profile on SciRah

×20

Invite

K. Nishida — researcher profile on SciRah

Shiro Manabe×14

Invite

Shiro Manabe — researcher profile on SciRah

Invite

M. Hori — researcher profile on SciRah

Invite

T. Oka — researcher profile on SciRah

Invite

Y. Higuchi — researcher profile on SciRah

Atsuko Nakai×10

Invite

Atsuko Nakai — researcher profile on SciRah

Manabu Taneike×10

Invite

Manabu Taneike — researcher profile on SciRah

Invite

M. Taniike — researcher profile on SciRah