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O. Harraz · SciRah

Researcher profile · Semantic Scholar

O. Harraz

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O. Harraz — researcher profile on SciRah

h-index: 25
Works: 76
Citations: 1,709

Most-cited papers

Mechanosensing by Vascular Endothelium
Xin-Rui Lim, O. Harraz
2023Annual Review of Physiology107 citations Open access
Semantic Scholar
PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells
O. Harraz, T. Longden, David Hill-Eubanks, M. Nelson
2018eLife104 citations Open access
Semantic Scholar
Piezo1 Is a Mechanosensor Channel in Central Nervous System Capillaries
O. Harraz, Nicholas R. Klug, Amanda J. Senatore, David Hill-Eubanks +1 more
2022Circulation Research101 citations Open access
Semantic Scholar
Local IP3 receptor–mediated Ca2+ signals compound to direct blood flow in brain capillaries
Thomas A. Longden, A. Mughal, G. Hennig, O. Harraz +9 more
2021Science Advances95 citations Open access
Semantic Scholar
Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP2 depletion
O. Harraz, T. Longden, F. Dabertrand, David Hill-Eubanks +1 more
2018Proceedings of the National Academy of Sciences of the United States of America92 citations Open access
Semantic Scholar
Identification of L- and T-type Ca2+ channels in rat cerebral arteries: role in myogenic tone development.
Rasha R. Abd El-Rahman, O. Harraz, S. Brett, Y. Anfinogenova +3 more
2013American Journal of Physiology. Heart and Circulatory Physiology89 citations Open access
Semantic Scholar
PIP2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity
F. Dabertrand, O. Harraz, M. Koide, T. Longden +4 more
2021Proceedings of the National Academy of Sciences of the United States of America85 citations Open access
Semantic Scholar
The capillary Kir channel as sensor and amplifier of neuronal signals: Modeling insights on K+-mediated neurovascular communication
A. Moshkforoush, Baarbod Ashenagar, O. Harraz, F. Dabertrand +3 more
2020Proceedings of the National Academy of Sciences of the United States of America68 citations Open access
Semantic Scholar
CaV3.2 Channels and the Induction of Negative Feedback in Cerebral Arteries
O. Harraz, Rasha R. Abd El-Rahman, Kamran Bigdely-Shamloo, Sean M. Wilson +16 more
2014Circulation Research64 citations Open access
Semantic Scholar
TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw
C. Gomes, T. Gayden, Andrea Bajic, O. Harraz +19 more
2018Nature Communications63 citations Open access
Semantic Scholar
Endothelial Piezo1 channel mediates mechano-feedback control of brain blood flow
Xin-Rui Lim, Mohammed Abd-Alhaseeb, Michael J. Ippolito, Masayo Koide +12 more
2024Nature Communications62 citations Open access
Semantic Scholar
PIP2: A critical regulator of vascular ion channels hiding in plain sight
O. Harraz, David Hill-Eubanks, M. Nelson
2020Proceedings of the National Academy of Sciences of the United States of America60 citations Open access
Semantic Scholar
PIP2 Improves Cerebral Blood Flow in a Mouse Model of Alzheimer’s Disease
A. Mughal, O. Harraz, Albert L. Gonzales, David Hill-Eubanks +1 more
2021Function55 citations Open access
Semantic Scholar
Zinc drives vasorelaxation by acting in sensory nerves, endothelium and smooth muscle
A. Betrie, J. Brock, O. Harraz, A. Bush +5 more
2021Nature Communications49 citations Open access
Semantic Scholar
CaV1.2/CaV3.x channels mediate divergent vasomotor responses in human cerebral arteries
O. Harraz, Frank E. Visser, S. Brett, D. Goldman +6 more
2015The Journal of General Physiology46 citations Open access
Semantic Scholar
STIM1-mediated bidirectional regulation of Ca2+ entry through voltage-gated calcium channels (VGCC) and calcium-release activated channels (CRAC)
O. Harraz, C. Altier
2014Frontiers in Cellular Neuroscience46 citations Open access
Semantic Scholar
Vascular calcium signalling and ageing
O. Harraz, L. J. Jensen
2021Journal of Physiology45 citations Open access
Semantic Scholar
Nitric oxide suppresses vascular voltage-gated T-type Ca2+ channels through cGMP/PKG signaling.
O. Harraz, S. Brett, D. Welsh
2014American Journal of Physiology. Heart and Circulatory Physiology44 citations
Semantic Scholar
Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel diseases.
M. Koide, O. Harraz, F. Dabertrand, T. Longden +5 more
2021Journal of Clinical Investigation43 citations Open access
Semantic Scholar
Genetic Ablation of CaV3.2 Channels Enhances the Arterial Myogenic Response by Modulating the RyR-BKCa Axis
O. Harraz, S. Brett, A. Zechariah, M. Romero +3 more
2015Arteriosclerosis, Thrombosis and Vascular Biology41 citations Open access
Semantic Scholar
Aging, calcium channel signaling and vascular tone
O. Harraz, L. J. Jensen
2020Mechanisms of Ageing and Development39 citations Open access
Semantic Scholar
Protein kinase A regulation of T-type Ca2+ channels in rat cerebral arterial smooth muscle
O. Harraz, D. Welsh
2013Journal of Cell Science37 citations
Semantic Scholar
Do TRPC-like currents and G protein-coupled receptors interact to facilitate myogenic tone development?
Y. Anfinogenova, S. Brett, M. Walsh, O. Harraz +1 more
2011American Journal of Physiology. Heart and Circulatory Physiology34 citations
Semantic Scholar
Recent Insights into Channelopathies.
O. Harraz, E. Delpire
2023Physiological Reviews28 citations
Semantic Scholar
Facilitation of central imidazoline I1‐site/extracellular signal‐regulated kinase/p38 mitogen‐activated protein kinase signalling mediates the hypotensive effect of ethanol in rats with acute renal failure
M. El-Mas, Hanan M. El-Gowelli, A. Ghazal, O. Harraz +1 more
2009British Journal of Pharmacology28 citations Open access
Semantic Scholar
Caveolae Link CaV3.2 Channels to BKCa-Mediated Feedback in Vascular Smooth Muscle
A. Hashad, O. Harraz, S. Brett, M. Romero +5 more
2018Arteriosclerosis, Thrombosis and Vascular Biology21 citations
Semantic Scholar
Diversity of Cells and Signals in the Cardiovascular System
Eleonora Grandi, Manuel F. Navedo, J. Saucerman, D. Bers +14 more
2023Journal of Physiology18 citations Open access
Semantic Scholar
T‐Type Ca2+ Channels in Cerebral Arteries: Approaches, Hypotheses, and Speculation
O. Harraz, D. Welsh
2013Microcirculation16 citations
Semantic Scholar
Distinct Potassium Channel Types in Brain Capillary Pericytes.
María Sancho, Nicholas R. Klug, O. Harraz, David Hill-Eubanks +1 more
2024Biophysical Journal15 citations Open access
Semantic Scholar
Traumatic Brain Injury Impairs Systemic Vascular Function Through Disruption of Inward-Rectifier Potassium Channels
Adrian M. Sackheim, Nuria Villalba, M. Sancho, O. Harraz +5 more
2021Function15 citations Open access
Semantic Scholar
Interplay among distinct Ca2+ conductances drives Ca2+ sparks/spontaneous transient outward currents in rat cerebral arteries
A. Hashad, Neil Mazumdar, M. Romero, A. Nygren +6 more
2016Journal of Physiology15 citations Open access
Semantic Scholar
Brain Capillary Ion Channels: Physiology and Channelopathies
O. Harraz, A. Hashad
2025Physiology13 citations Open access
Semantic Scholar
PIP2 corrects an endothelial Piezo1 channelopathy
A. Hashad, Mohammed Abd-Alhaseeb, Xin-Rui Lim, N. Mathieu +1 more
2025Proceedings of the National Academy of Sciences of the United States of America11 citations Open access
Semantic Scholar
Amyloid beta Aβ1-40 activates Piezo1 channels in brain capillary endothelial cells.
Xin-Rui Lim, Luc Willemse, O. Harraz
2024Biophysical Journal9 citations
Semantic Scholar
Nitric Oxide Suppresses Vascular Voltage-gated T-type Ca 2ϩ Channels through Cgmp/pkg Signaling
O. Harraz, S. Brett, D. Welsh, D. Welsh
7 citations
Semantic Scholar
Systemic Piezo1 activation improves cerebrovascular function in Alzheimer's disease
Zeynab Tabrizi, Xin-Rui Lim, Supriya Chakraborty, O. Harraz +1 more
2025Alzheimer's & Dementia6 citations Open access
Semantic Scholar
Piezo1 is a mechanosensor channel in CNS capillaries.
O. Harraz, Nicholas R. Klug, Amanda J. Senatore, M. Koide +1 more
2021The Journal of General Physiology6 citations Open access
Semantic Scholar
Adenosinergic Modulation Of The Imidazoline I1‐Receptor‐Dependent Hypotensive Effect Of Ethanol In Acute Renal Failure
M. El-Mas, Hanan M. El-Gowelli, O. Harraz, A. Ghazal +1 more
2010Food and Chemical Toxicology6 citations
Semantic Scholar
A new model for evaluating pressure-induced vascular tone in small cerebral arteries
A. Coccarelli, Sanjay Pant, Ioannis Polydoros, O. Harraz
2023Biomechanics and Modeling in Mechanobiology5 citations Open access
Semantic Scholar
Endothelial Cell Metabolism and Vascular Function: A Paradigm Shift?
O. Harraz
2023Function4 citations Open access
Semantic Scholar
A computational framework for quantifying blood flow dynamics across myogenically-active cerebral arterial networks
A. Coccarelli, Ioannis Polydoros, Alex Drysdale, O. Harraz +1 more
2025Biomechanics and Modeling in Mechanobiology3 citations Open access
Semantic Scholar
Estrogen Enhances SK Channel Activity to Limit Hippocampal Arteriole Constriction
Danielle A. Jeffrey, Abigail N Russell, Hannah R Ferris, Phinea Z. Romero +8 more
2025Circulation Research3 citations Open access
Semantic Scholar
Neural activity drives dynamic Ca2+ signals in capillary endothelial cells that shape local brain blood flow
T. Longden, O. Harraz, G. Hennig, Bo Shui +8 more
2019The FASEB Journal3 citations
Semantic Scholar
Tau protein differentially affects Piezo1 and Kir2.1 channels in brain capillary endothelial cells
Trevor Harriman, O. Harraz
2026Biophysical Journal1 citations Open access
Semantic Scholar
Translating cardiovascular ion channel and Ca2+ signaling mechanisms into therapeutic insights
S. Marchiano, Miguel A. S. Martín-Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez +15 more
2026Journal of Physiology1 citations Open access
Semantic Scholar
VasoTracker 2: Open‐source software and hardware for tracking blood vessel diameter and assessing vascular function
Matthew D. Lee, Christopher Osborne, Ross Stevenson, Amy MacDonald +12 more
2025Journal of Physiology1 citations Open access
Semantic Scholar
Evidence of an excitatory purinergic innervation in mouse corpus cavernosum smooth muscle.
Xin-Rui Lim, Mitchell Mercer, O. Harraz, M. Hollywood +2 more
2024Journal of Sexual Medicine1 citations Open access
Semantic Scholar
Editorial: Small and mighty: Brain capillaries in health and disease
O. Bracko, O. Harraz
2022Frontiers in Molecular Neuroscience1 citations Open access
Semantic Scholar
Modelling and Simulation of Lightning Electromagnetic Fields Using an Hybrid Method for Poorly Conducting Ground Case
A. Mimouni, Z. Azzouz, O. Harraz, B. Guemri +1 more
20151 citations
Semantic Scholar
Protein kinase A‐mediated inhibition of T‐type Ca2+ channels in the cerebral circulation
O. Harraz, D. Welsh
20121 citations
Semantic Scholar

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M. Nelson×12
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S. Brett×8
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A. Hashad — researcher profile on SciRah

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