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Adrian M. Sackheim · SciRah

Researcher profile · Semantic Scholar

Adrian M. Sackheim

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Adrian M. Sackheim — researcher profile on SciRah

h-index: 9
Works: 18
Citations: 289

Most-cited papers

Traumatic Brain Injury Causes Endothelial Dysfunction in the Systemic Microcirculation through Arginase-1–Dependent Uncoupling of Endothelial Nitric Oxide Synthase
Nuria Villalba, Adrian M. Sackheim, I. Nunez, David Hill-Eubanks +3 more
2017Journal of Neurotrauma82 citations Open access
Semantic Scholar
Traumatic Brain Injury Disrupts Cerebrovascular Tone Through Endothelial Inducible Nitric Oxide Synthase Expression and Nitric Oxide Gain of Function
Nuria Villalba, Swapnil K. Sonkusare, T. Longden, Tram L. Tran +4 more
2014Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease60 citations Open access
Semantic Scholar
Extracellular histones induce calcium signals in the endothelium of resistance-sized mesenteric arteries and cause loss of endothelium-dependent dilation.
Daniel M. Collier, Nuria Villalba, Adrian M. Sackheim, A. Bonev +9 more
2019American Journal of Physiology. Heart and Circulatory Physiology41 citations Open access
Semantic Scholar
Increased histone-DNA complexes and endothelial-dependent thrombin generation in severe COVID-19
B. Bouchard, C. Colovos, M. Lawson, Zachary T. Osborn +6 more
2021bioRxiv17 citations Open access
Semantic Scholar
Traumatic brain injury impairs sensorimotor function in mice
Adrian M. Sackheim, David W. Stockwell, Nuria Villalba, Laurel Haines +4 more
2017Journal of Surgical Research17 citations Open access
Semantic Scholar
Traumatic Brain Injury Impairs Systemic Vascular Function Through Disruption of Inward-Rectifier Potassium Channels
Adrian M. Sackheim, Nuria Villalba, M. Sancho, O. Harraz +5 more
2021Function15 citations Open access
Semantic Scholar
The polyanionic drug suramin neutralizes histones and prevents endotheliopathy
Nuria Villalba, Adrian M. Sackheim, M. A. Lawson, Laurel Haines +10 more
2021bioRxiv15 citations Open access
Semantic Scholar
Impaired capillary-to-arteriolar electrical signaling after traumatic brain injury
A. Mughal, Adrian M. Sackheim, M. Sancho, T. Longden +4 more
2020Journal of Cerebral Blood Flow and Metabolism13 citations Open access
Semantic Scholar
Pathogenic soluble tau peptide disrupts endothelial calcium signaling and vasodilation in the brain microvasculature
A. Mughal, Adrian M. Sackheim, M. Koide, Grace Bonson +5 more
2024Journal of Cerebral Blood Flow and Metabolism9 citations Open access
Semantic Scholar
Dense and dangerous: The tissue plasminogen activator-resistant fibrinolysis shutdown phenotype is due to abnormal fibrin polymerization
Nathan W Dow, Julia R. Coleman, H. Moore, Zachary T. Osborn +6 more
2019Journal of Trauma and Acute Care Surgery9 citations Open access
Semantic Scholar
Distinct Patterns of Endothelial Cell Activation Produced by Extracellular Histones and Bacterial Lipopolysaccharide
S. H. Piffard, Grant W. Hennig, Adrian M. Sackheim, Abigail J. Howard +4 more
2024Shock4 citations
Semantic Scholar
Pathogenic soluble tau peptide disrupts endothelial calcium signaling and vasodilation in the brain microvasculature
Kalev Freeman, Adrian M. Sackheim, A. Mughal, M. Koide +5 more
2023bioRxiv4 citations Open access
Semantic Scholar
Endothelial-specific knockout of the scramblase TMEM16F impairs in vivo clot formation
Grace Bonson, Aaron R Lambert, Adrian M. Sackheim, Abigail J. Howard +9 more
2025Shock2 citations Open access
Semantic Scholar
Myogenic tone contributes to the regulation of permeability in mesenteric microvessels
Laurel Haines, Nuria Villalba, Adrian M. Sackheim, Daniel M. Collier +1 more
2019Microvascular Research2 citations Open access
Semantic Scholar
Syndecan-1 Levels in Trauma and Burn Patients Remain Elevated During Resuscitation and Correlate With Coagulopathy
Grace Bonson, Peter Callas, M. Bravo, T. Orfeo +9 more
2026Journal of the American College of Emergency Physicians Open1 citations Open access
Semantic Scholar
Endothelial Trauma Depends on Surface Charge and Extracellular Calcium Levels
Jade H. Cleary, Kara J. Wentzel, Abigail J. Howard, Adrian M. Sackheim +10 more
2025bioRxiv0 citations Open access
Semantic Scholar
Traumatic Brain Injury Impairs Systemic Vascular Function Through Altered Lipid Metabolism and Disruption of Inward-Rectifier Potassium (Kir2.1) Channels
Adrian M. Sackheim, Nuria Villalba, M. Sancho, O. Harraz +5 more
2021bioRxiv0 citations Open access
Semantic Scholar
Extracellular Histones Trigger Endothelial Calcium Signals that Paradoxically do not Cause Vasodilation, and Instead, Compromise Endothelial Function
Daniel M. Collier, Nuria Villalba, Adrian M. Sackheim, Adrian M. Bonev +2 more
20180 citations
Semantic Scholar

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Kalev Freeman×13
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Kalev Freeman — researcher profile on SciRah
Nuria Villalba×9
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M. Nelson×8
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Grant W. Hennig×5
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Devdoot Majumdar×4

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Daniel M. Collier×3

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