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E. Delpire · SciRah

Researcher profile · Semantic Scholar

E. Delpire

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E. Delpire — researcher profile on SciRah

h-index: 70
Works: 302
Citations: 16K

Most-cited papers

Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus
J. Karimy, Jin-Wei Zhang, David B. Kurland, B. Theriault +15 more
2017Nature Medicine351 citations
Semantic Scholar
GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions.
Danielle M. Gerhard, Santosh Pothula, Rong-Jian Liu, Min Wu +8 more
2019Journal of Clinical Investigation302 citations Open access
Semantic Scholar
WNK Kinase Signaling in Ion Homeostasis and Human Disease.
M. Shekarabi, Jin-Wei Zhang, A. Khanna, D. Ellison +2 more
2017Cell Metabolism207 citations Open access
Semantic Scholar
The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus
S. Robert, Benjamin C. Reeves, E. Kiziltug, Phan Q. Duy +33 more
2023Cell131 citations Open access
Semantic Scholar
Water Homeostasis and Cell Volume Maintenance and Regulation
E. Delpire, K. Gagnon
2018Current topics in membranes99 citations Open access
Semantic Scholar
Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening
D. Marcus, G. Bedse, Andrew D. Gaulden, J. Ryan +8 more
2020Neuron96 citations Open access
Semantic Scholar
Chloride dysregulation, seizures, and cerebral edema: a relationship with therapeutic potential
J. Glykys, V. Dzhala, Kiyoshi Egawa, K. Kahle +2 more
2017Trends in Neurosciences95 citations Open access
Semantic Scholar
Constitutively Active SPAK Causes Hyperkalemia by Activating NCC and Remodeling Distal Tubules.
P. Grimm, R. Coleman, E. Delpire, P. Welling
2017Journal of the American Society of Nephrology95 citations Open access
Semantic Scholar
Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway
Justin S. A. Perry, S. Morioka, Christopher B. Medina, J. Etchegaray +6 more
2019Nature Cell Biology94 citations Open access
Semantic Scholar
Mechanism of Hyperkalemia-Induced Metabolic Acidosis.
Autumn N. Harris, P. Grimm, Hyun-Wook Lee, E. Delpire +4 more
2018Journal of the American Society of Nephrology85 citations Open access
Semantic Scholar
Cryo-EM structures of the human cation-chloride cotransporter KCC1
Si Liu, Sheng-Hai Chang, Binming Han, Lingyi Xu +9 more
2019Science79 citations
Semantic Scholar
Locus coeruleus anchors a trisynaptic circuit controlling fear-induced suppression of feeding
Ben Yang, Javier Sanches-Padilla, Jyothisri Kondapalli, Sage L. Morison +3 more
2021Neuron65 citations Open access
Semantic Scholar
Na+‐K+‐2Cl− Cotransporter (NKCC) Physiological Function in Nonpolarized Cells and Transporting Epithelia
E. Delpire, K. Gagnon
2018Comprehensive Physiology65 citations Open access
Semantic Scholar
Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival
Miho Watanabe, Jin-Wei Zhang, M. Mansuri, J. Duan +6 more
2019Science Signaling60 citations Open access
Semantic Scholar
Structures and an activation mechanism of human potassium-chloride cotransporters
Yuan Xie, Sheng-Hai Chang, Cheng Zhao, Feng Wang +5 more
2020Science Advances57 citations Open access
Semantic Scholar
Sodium Transporters in Human Health and Disease
K. Gagnon, E. Delpire
2021Frontiers in Physiology55 citations Open access
Semantic Scholar
A missense mutation in SLC6A1 associated with Lennox-Gastaut syndrome impairs GABA transporter 1 protein trafficking and function
Kefu Cai, Jie Wang, Jaclyn Eissman, Jue-Xin Wang +12 more
2019Experimental Neurology51 citations Open access
Semantic Scholar
Endoplasmic reticulum retention and degradation of a mutation in SLC6A1 associated with epilepsy and autism
Jie Wang, Sarah Poliquin, Felicia Mermer, Jaclyn Eissman +12 more
2020Molecular Brain50 citations Open access
Semantic Scholar
NKCC1: Newly Found as a Human Disease-Causing Ion Transporter
Rainelli B. Koumangoye, L. Bastarache, E. Delpire
2020Function47 citations Open access
Semantic Scholar
Large-Scale Proteomic Assessment of Urinary Extracellular Vesicles Highlights Their Reliability in Reflecting Protein Changes in the Kidney
Qi Wu, S. Poulsen, S. Murali, Paul Grimm +5 more
2021Journal of the American Society of Nephrology45 citations Open access
Semantic Scholar
SLC12A2 variants cause a neurodevelopmental disorder or cochleovestibular defect.
A. McNeill, Emanuela Iovino, Luke Mansard, C. Vaché +16 more
2020Brain : a journal of neurology44 citations Open access
Semantic Scholar
Sex-dependent modulation of anxiety and fear by 5-HT1A receptors in the bed nucleus of the stria terminalis
C. Marcinkiewcz, Gabrielle Bierlein-De La Rosa, Cayce E. Dorrier, Mackenzie McKnight +8 more
2019ACS Chemical Neuroscience29 citations Open access
Semantic Scholar
Recent Insights into Channelopathies.
O. Harraz, E. Delpire
2023Physiological Reviews28 citations
Semantic Scholar
Collagen IVα345 dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture’s and Alport diseases
E. Pokidysheva, H. Seeger, V. Pedchenko, S. Chetyrkin +26 more
2021Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Implications of the N-terminal heterogeneity for the neuronal K-Cl cotransporter KCC2 function.
M. Markkanen, Anastasia Ludwig, Stanislav Khirug, E. Pryazhnikov +6 more
2017Brain Research26 citations Open access
Semantic Scholar
Agmatine requires GluN2B-containing NMDA receptors to inhibit the development of neuropathic pain
Cristina D. Peterson, Kelley F. Kitto, Harsha Verma, Kelsey R. Pflepsen +3 more
2021Molecular Pain24 citations Open access
Semantic Scholar
A role for KCC3 in maintaining cell volume of peripheral nerve fibers
Bianca Flores, Cara C. Schornak, E. Delpire
2018Neurochemistry International24 citations Open access
Semantic Scholar
Dietary Anions Control Potassium Excretion; it is More Than a Poorly Absorbable Anion Effect.
Lama Al-Qusairi, M. Ferdaus, T. Pham, Dimin Li +7 more
2023AJP - Renal Physiology23 citations
Semantic Scholar
SLC12A ion transporter mutations in sporadic and familial human congenital hydrocephalus
Sheng-Chih Jin, Charuta G. Furey, Xue Zeng, August Allocco +7 more
2019Molecular Genetics & Genomic Medicine22 citations Open access
Semantic Scholar
Novel Human NKCC1 Mutations Cause Defects in Goblet Cell Mucus Secretion and Chronic Inflammation
Rainelli B. Koumangoye, Salma Omer, M. Kabeer, E. Delpire
2019Cellular and Molecular Gastroenterology and Hepatology22 citations Open access
Semantic Scholar
Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling
M. Moseng, Chih-Chia Su, Kerri Rios, Meng Cui +5 more
2022Science Advances21 citations Open access
Semantic Scholar
Opposing retrograde and astrocyte-dependent endocannabinoid signaling mechanisms regulate lateral habenula synaptic transmission
Nathan D. Winters, Veronika Kondev, Niharika Loomba, E. Delpire +2 more
2023Cell Reports20 citations Open access
Semantic Scholar
Advances in the development of novel compounds targeting cation-chloride cotransporter physiology.
E. Delpire
2020American Journal of Physiology - Cell Physiology20 citations Open access
Semantic Scholar
Mistargeting of a truncated Na-K-2Cl cotransporter in epithelial cells.
Rainelli B. Koumangoye, Salma Omer, E. Delpire
2018American Journal of Physiology - Cell Physiology20 citations Open access
Semantic Scholar
Discovery of Small Molecule KCC2 Potentiators Which Attenuate In Vitro Seizure-Like Activity in Cultured Neurons
Francis J. Prael, Kwangho Kim, Yu Du, B. Spitznagel +3 more
2022Frontiers in Cell and Developmental Biology19 citations Open access
Semantic Scholar
Loss of non‐canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons
Martina Mavrovic, Pavel Uvarov, E. Delpire, L. Vutskits +2 more
2020EMBO Reports19 citations Open access
Semantic Scholar
Elusive role of the Na-K-2Cl cotransporter in the choroid plexus.
E. Delpire, K. Gagnon
2019American Journal of Physiology - Cell Physiology19 citations Open access
Semantic Scholar
A Wholistic View of How Bumetanide Attenuates Autism Spectrum Disorders
E. Delpire, Yehezkel Ben-Ari
2022Cells18 citations Open access
Semantic Scholar
Multiple molecular mechanisms are involved in the activation of the kidney sodium-chloride cotransporter by hypokalemia
A. Murillo-de-Ozores, Héctor Carbajal-Contreras, Germán Magaña-Ávila, R. Valdés +11 more
2022Kidney International17 citations Open access
Semantic Scholar
Pharmacological targeting of SPAK kinase in disorders of impaired epithelial transport
Jin-Wei Zhang, J. Karimy, E. Delpire, K. Kahle
2017Expert opinion on therapeutic targets17 citations Open access
Semantic Scholar
The cryo-EM structures of DrNKCC1 and hKCC1: a new milestone in the physiology of cation-chloride cotransporters.
E. Delpire, Jiangtao Guo
2019American Journal of Physiology - Cell Physiology16 citations Open access
Semantic Scholar
AMPA Receptor Auxiliary Subunit GSG1L Suppresses Short-Term Facilitation in Corticothalamic Synapses and Determines Seizure Susceptibility
A. Kamalova, K. Futai, E. Delpire, Terunaga Nakagawa
2020Cell Reports15 citations Open access
Semantic Scholar
The Kainate Receptor Subunit GluK2 Interacts With KCC2 to Promote Maturation of Dendritic Spines
S. Kesaf, Stanislav Khirug, E. Dinh, M. Saez Garcia +6 more
2020Frontiers in Cellular Neuroscience15 citations Open access
Semantic Scholar
Enhanced social dominance and altered neuronal excitability in the prefrontal cortex of male KCC2b mutant mice
Allison M. J. Anacker, Jacqueline T. Moran, Sara Santarelli, C. G. Forsberg +6 more
2019Autism Research15 citations Open access
Semantic Scholar
Kidney Injury Causes Accumulation of Renal Sodium That Modulates Renal Lymphatic Dynamics
Jing Liu, Elaine L. Shelton, R. Crescenzi, D. Colvin +5 more
2022International Journal of Molecular Sciences14 citations Open access
Semantic Scholar
De novo variants in SLC12A6 cause sporadic early-onset progressive sensorimotor neuropathy
Joohyun Park, Bianca Flores, Katalin Scherer, H. Kuepper +10 more
2019Journal of Medical Genetics14 citations Open access
Semantic Scholar
The KCC3 cotransporter as a therapeutic target for peripheral neuropathy
E. Delpire, K. Kahle
2017Expert opinion on therapeutic targets14 citations Open access
Semantic Scholar
Loss of KCC2 in GABAergic Neurons Causes Seizures and an Imbalance of Cortical Interneurons
Kirill Zavalin, A. Hassan, C. Fu, E. Delpire +1 more
2022Frontiers in Molecular Neuroscience13 citations Open access
Semantic Scholar
KCC3a, a Strong Candidate Pathway for K+ Loss in Alkalemia
M. Ferdaus, A. Terker, Rainelli B. Koumangoye, E. Delpire
2022Frontiers in Cell and Developmental Biology12 citations Open access
Semantic Scholar
Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression.
Rainelli B. Koumangoye, Parker Penny, E. Delpire
2022American Journal of Physiology - Cell Physiology12 citations Open access
Semantic Scholar

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K. Kahle×7
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K. Kahle — researcher profile on SciRah
J. Karimy×5
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J. Karimy — researcher profile on SciRah
Jin-Wei Zhang×5
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Jin-Wei Zhang — researcher profile on SciRah
Rainelli B. Koumangoye×5
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Rainelli B. Koumangoye — researcher profile on SciRah

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K. Gagnon — researcher profile on SciRah

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P. Welling — researcher profile on SciRah

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M. Mansuri — researcher profile on SciRah

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D. Ellison — researcher profile on SciRah

Jiangtao Guo×3

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Jiangtao Guo — researcher profile on SciRah

Charuta G. Furey×2

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Charuta G. Furey — researcher profile on SciRah

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M. DiLuna — researcher profile on SciRah

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S. Alper — researcher profile on SciRah