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Xin Du · SciRah

Researcher profile · Semantic Scholar

Xin Du

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Xin Du — researcher profile on SciRah

h-index: 26
Works: 51
Citations: 3,320

Most-cited papers

CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex.
Xue-Rong Shi, L. Leng, Tian Wang, Wen-Kui Wang +9 more
2006Immunity686 citations Open access
Semantic Scholar
Chidamide (CS055/HBI-8000): a new histone deacetylase inhibitor of the benzamide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity
Z. Ning, Zhi-Bin Li, M. Newman, Song Shan +6 more
2012Cancer Chemotherapy and Pharmacology271 citations
Semantic Scholar
The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)
M. Merk, S. Zierow, L. Leng, Rituparna Das +12 more
2011Proceedings of the National Academy of Sciences of the United States of America226 citations Open access
Semantic Scholar
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
Yoonsang Cho, G. Crichlow, Jon J. Vermeire, L. Leng +8 more
2010Proceedings of the National Academy of Sciences of the United States of America200 citations Open access
Semantic Scholar
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
D. Kono, M. Haraldsson, B. Lawson, K. Pollard +7 more
2009Proceedings of the National Academy of Sciences of the United States of America165 citations Open access
Semantic Scholar
A Tautomerase-Null Macrophage Migration-Inhibitory Factor (MIF) Gene Knock-In Mouse Model Reveals That Protein Interactions and Not Enzymatic Activity Mediate MIF-Dependent Growth Regulation
G. Fingerle-Rowson, Dayananda Rao Kaleswarapu, Corinna Schlander, Nazanin Kabgani +14 more
2009Molecular and Cellular Biology145 citations Open access
Semantic Scholar
Discovery of Human Macrophage Migration Inhibitory Factor (MIF)-CD74 Antagonists via Virtual Screening
Z. Cournia, L. Leng, Sunilkumar Gandavadi, Xin Du +2 more
2009Journal of Medicinal Chemistry136 citations Open access
Semantic Scholar
A Small Molecule MIF Antagonist Protects against Glomerulonephritis in Lupus-prone NZB/NZW F1 and MRL/lpr Mice
L. Leng, Liang Chen, Juan Fan, D. Greven +10 more
2010Journal of Immunology135 citations Open access
Semantic Scholar
PTPN2 phosphatase deletion in T cells promotes anti‐tumour immunity and CAR T‐cell efficacy in solid tumours
F. Wiede, K. Lu, Xin Du, Shuwei Liang +15 more
2019EMBO Journal121 citations Open access
Semantic Scholar
THE ROLE OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) IN AUTOIMMUNE LIVER DISEASE
D. Assis, L. Leng, Xin Du, Clarence K. Zhang +13 more
2013Hepatology97 citations Open access
Semantic Scholar
ITGBL1 Is a Runx2 Transcriptional Target and Promotes Breast Cancer Bone Metastasis by Activating the TGFβ Signaling Pathway.
Xiao-Qing Li, Xin Du, Dong-Mei Li, P. Kong +4 more
2015Cancer Research96 citations Open access
Semantic Scholar
MIF and D-DT are potential disease severity modifiers in male MS subjects
G. Benedek, R. Meza-Romero, Kelley R. Jordan, Ying Zhang +17 more
2017Proceedings of the National Academy of Sciences of the United States of America86 citations Open access
Semantic Scholar
FOXF2 suppresses the FOXC2-mediated epithelial-mesenchymal transition and multidrug resistance of basal-like breast cancer.
Jun Cai, Ai Tian, Qing-Shan Wang, P. Kong +3 more
2015Cancer Letters78 citations Open access
Semantic Scholar
MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis
S. Yoo, L. Leng, B. Kim, Xin Du +14 more
2016Proceedings of the National Academy of Sciences of the United States of America74 citations Open access
Semantic Scholar
The effect of human tissue factor pathway inhibitor-2 on the growth and metastasis of fibrosarcoma tumors in athymic mice.
H. Chand, Xin Du, Duan Ma, H. Inzunza +4 more
2004Blood73 citations
Semantic Scholar
Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF)
Alissa A. Hare, L. Leng, Sunilkumar Gandavadi, Xin Du +3 more
2010Bioorganic & Medicinal Chemistry Letters70 citations Open access
Semantic Scholar
Receptor agonists of macrophage migration inhibitory factor
W. L. Jorgensen, Sunilkumar Gandavadi, Xin Du, Alissa A. Hare +3 more
2010Bioorganic & Medicinal Chemistry Letters60 citations Open access
Semantic Scholar
Long Noncoding RNA HOXA-AS2 Promotes Papillary Thyroid Cancer Progression by Regulating miR-520c-3p/S100A4 Pathway
Fa-Da Xia, Yong Chen, Bo Jiang, Xin Du +5 more
2018Cellular Physiology and Biochemistry58 citations Open access
Semantic Scholar
Breast cancer cells obtain an osteomimetic feature via epithelial-mesenchymal transition that have undergone BMP2/RUNX2 signaling pathway induction
Cong-Cong Tan, Gui-Xi Li, L. Tan, Xin Du +4 more
2016OncoTarget56 citations Open access
Semantic Scholar
Transcription factor ICBP90 regulates the MIF promoter and immune susceptibility locus.
Jie Yao, L. Leng, M. Sauler, Wei-Ling Fu +6 more
2016Journal of Clinical Investigation56 citations Open access
Semantic Scholar
HYOU1 facilitates proliferation, invasion and glycolysis of papillary thyroid cancer via stabilizing LDHB mRNA
Jia-Mei Wang, Jing-Yi Jiang, Da-Lin Zhang, Xin Du +2 more
2021Journal of Cellular and Molecular Medicine34 citations Open access
Semantic Scholar
Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors
Yoonsang Cho, Jon J. Vermeire, J. Merkel, L. Leng +4 more
2011Chemistry and Biology33 citations Open access
Semantic Scholar
A Histone Deacetylase Inhibitor, Panobinostat, Enhances Chimeric Antigen Receptor T-cell Antitumor Effect Against Pancreatic Cancer
Aesha I. Ali, Min-Yu Wang, B. von Scheidt, Pilar M. Dominguez +12 more
2021Clinical Cancer Research30 citations Open access
Semantic Scholar
A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity
P. Tilstam, G. Pantouris, M. Corman, M. Andreoli +6 more
2019Journal of Biological Chemistry29 citations Open access
Semantic Scholar
TRIM29 inhibits miR-873-5P biogenesis via CYTOR to upregulate fibronectin 1 and promotes invasion of papillary thyroid cancer cells
Tong Wu, Da-Lin Zhang, Jia-Mei Wang, Jing-Yi Jiang +3 more
2020Cell Death and Disease28 citations Open access
Semantic Scholar
The detection of ESR1/PGR/ERBB2 mRNA levels by RT-QPCR: a better approach for subtyping breast cancer and predicting prognosis
Xin Du, Xiao-Qing Li, Lin Li, Yuan-Yuan Xu +1 more
2013Breast Cancer Research and Treatment28 citations
Semantic Scholar
Enhancing co-stimulation of CAR T cells to improve treatment outcomes in solid cancers
Aaron J Harrison, Xin Du, B. von Scheidt, M. Kershaw +1 more
2021Immunotherapy Advances25 citations Open access
Semantic Scholar
Cardiomyocyte d-dopachrome tautomerase protects against heart failure.
Yina Ma, K. N. Su, Daniel Pfau, Veena S. Rao +12 more
2019JCI Insight25 citations Open access
Semantic Scholar
Benzisothiazolones as modulators of macrophage migration inhibitory factor
W. L. Jorgensen, A. Trofimov, Xin Du, Alissa A. Hare +2 more
2011Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
Ostertagia ostertagi macrophage migration inhibitory factor is present in all developmental stages and may cross-regulate host functions through interaction with the host receptor
Guang-Gang Qu, R. Fetterer, L. Leng, Xin Du +5 more
2014International Journal of Parasitology23 citations Open access
Semantic Scholar
Force-dependent calcium signaling and its pathway of human neutrophils on P-selectin in flow
Bing Huang, Yingchen Ling, Jiang-Guo Lin, Xin Du +2 more
2017Protein & Cell21 citations Open access
Semantic Scholar
Human tissue factor pathway inhibitor-2 does not bind or inhibit activated matrix metalloproteinase-1.
Xin Du, H. Chand, W. Kisiel
2003Biochimica et Biophysica Acta19 citations
Semantic Scholar
BAG5 promotes invasion of papillary thyroid cancer cells via upregulation of fibronectin 1 at the translational level.
Da-Lin Zhang, Jia-Mei Wang, Tong Wu, Xin Du +3 more
2020Biochimica et biophysica acta. Molecular cell research18 citations Open access
Semantic Scholar
Chimeric antibody targeting SRPK-1 in the treatment of non-small cell lung cancer by inhibiting growth, migration and invasion.
Fan Wu, Jie Li, Xin Du, Weisan Zhang +2 more
2017Molecular Medicine Reports17 citations Open access
Semantic Scholar
Prediction of novel target genes and pathways involved in tall cell variant papillary thyroid carcinoma
Fa-Da Xia, Bo Jiang, Yong Chen, Xin Du +4 more
2018Medicine16 citations Open access
Semantic Scholar
AUF1 Promotes Proliferation and Invasion of Thyroid Cancer via Downregulation of ZBTB2 and Subsequent TRIM58
Xin Du, Jia-Mei Wang, Da-Lin Zhang, Tong Wu +3 more
2021Frontiers in Oncology11 citations Open access
Semantic Scholar
ITGBL 1 Is a Runx 2 Transcriptional Target and Promotes Breast Cancer Bone Metastasis by Activating the TGF b Signaling Pathway
Xiao-Qing Li, Xin Du, Dong-Mei Li, P. Kong +4 more
201511 citations
Semantic Scholar
Identification of Serotonin as a Predictive Marker for Breast Cancer Patients
Qing-Qiang Xie, Xin Du, Meng-yao Wang, F. Xie +3 more
2021International Journal of General Medicine10 citations Open access
Semantic Scholar
Suppression of Plasmodium MIF-CD74 Signaling Protects Against Severe Malaria
Alvaro Baeza Garcia, Edwin Siu, Xin Du, L. Leng +6 more
2021bioRxiv9 citations Open access
Semantic Scholar
Molecular cloning, expression, and characterization of bovine tissue factor pathway inhibitor-2.
Xin Du, Fang-Ming Deng, H. Chand, W. Kisiel
2003Archives of Biochemistry and Biophysics8 citations
Semantic Scholar
Long non-coding RNA AB019562 promotes cell proliferation and metastasis in human hepatocellular carcinoma
Fan Wu, Jie Li, Xin Du, Weisan Zhang +2 more
2017Molecular Medicine Reports6 citations Open access
Semantic Scholar
Identification of key candidate genes and pathways in follicular variant papillary thyroid carcinoma by integrated bioinformatical analysis
Lanyu Jing, Fa-Da Xia, Xin Du, Bo Jiang +2 more
2020Translational Cancer Research5 citations Open access
Semantic Scholar
A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activity
Tilstam, G. Pantouris, M. Corman, Monica +7 more
20193 citations
Semantic Scholar
Retracted: Fibroblast Growth Factor Receptor 4 Polymorphisms Are Associated with Coronary Artery Disease
Hao Chen, Jiabin Tong, Tong Zou, Haifeng Shi +4 more
2012Genetic Testing and Molecular Biomarkers3 citations
Semantic Scholar
Abstract PR04: CRISPR-mediated PTPN2 deletion in CAR T cells enhances anti-tumor efficacy
Xin Du, F. Wiede, P. Darcy, T. Tiganis
2022Advances in Immune Cell Engineering2 citations
Semantic Scholar
AV411 (Ibudilast) and AV1013 are non-competitive inhibitors of macrophage migration inhibitory factor: a novel induced-fit allosteric inhibition mechanism (133.11)
Yoonsang Cho, G. Crichlow, Jon J. Vermeire, L. Leng +8 more
2010Journal of Immunology1 citations
Semantic Scholar
Long non-coding RNA DLX6-AS1 accelerates lipopolysaccharides-induced human AC16 cardiomyocytes apoptosis by regulating miR-497/CaSR axis
Guoheng Zhang, Yan-Fang Sun, Zhaohui Zhai, Y. Chu +2 more
2021Molecular & Cellular Toxicology0 citations
Semantic Scholar
Abstract 6707: Inhibition of proteolytic cleavage of NKG2D ligands increases immune cell-mediated cell killing of tumor cells in vitro
Safak Yalcin, Vanessa Cicchini, Xin Du, Xin Wu +2 more
2020Immunology0 citations
Semantic Scholar
PTPN2 deletion in T cells promotes anti-tumour immunity and CAR T cell efficacy in solid tumours
F. Wiede, K. Lu, Xin Du, Shuwei Liang +15 more
2019bioRxiv0 citations Open access
Semantic Scholar
Correlation between CX 3 CR 1 249 V / I polymorphism and premature coronary heart disease & blood lipid ratio
Q. Song, Yao-Fang Chu, Hai-Long Zhang, Xin Du +5 more
20160 citations
Semantic Scholar

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