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G. Crichlow · SciRah

Researcher profile · Semantic Scholar

G. Crichlow

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G. Crichlow — researcher profile on SciRah

h-index: 15
Works: 50
Citations: 3,697

Most-cited papers

RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences
S. Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich +34 more
2020Nucleic Acids Res.1,388 citations Open access
Semantic Scholar
RCSB Protein Data Bank (RCSB.org): delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from artificial intelligence/machine learning
S. Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich +37 more
2022Nucleic Acids Res.776 citations Open access
Semantic Scholar
Updated resources for exploring experimentally-determined PDB structures and Computed Structure Models at the RCSB Protein Data Bank
Stephen K. Burley, Rusham Bhatt, Charmi Bhikadiya, Chunxiao Bi +47 more
2024Nucleic Acids Research353 citations Open access
Semantic Scholar
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
Yoonsang Cho, G. Crichlow, Jon J. Vermeire, L. Leng +8 more
2010Proceedings of the National Academy of Sciences of the United States of America200 citations Open access
Semantic Scholar
RCSB Protein Data Bank: Celebrating 50 years of the PDB with new tools for understanding and visualizing biological macromolecules in 3D
S. Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich +31 more
2021Protein Science189 citations Open access
Semantic Scholar
Protein crystallization facilitated by molecularly imprinted polymers
E. Saridakis, S. Khurshid, L. Govada, Quan T Phan +5 more
2011Proceedings of the National Academy of Sciences of the United States of America129 citations Open access
Semantic Scholar
RCSB Protein Data bank: Tools for visualizing and understanding biological macromolecules in 3D
S. Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich +37 more
2022Protein Science113 citations Open access
Semantic Scholar
Structure of the extended-spectrum class C beta-lactamase of Enterobacter cloacae GC1, a natural mutant with a tandem tripeptide insertion.
G. Crichlow, A. P. Kuzin, M. Nukaga, K. Mayama +2 more
1999Biochemistry93 citations
Semantic Scholar
Physical characterization and crystallization of the carbohydrate-recognition domain of a mannose-binding protein from rat.
W. I. Weis, G. Crichlow, H. M. Murthy, W. A. Hendrickson +1 more
1991Journal of Biological Chemistry93 citations Open access
Semantic Scholar
Evolutionary conservation of intron position in a subfamily of genes encoding carbohydrate-recognition domains.
K. Bezouška, G. Crichlow, J. Rose, M. Taylor +1 more
1991Journal of Biological Chemistry83 citations Open access
Semantic Scholar
Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition
G. Crichlow, Hongwen Zhou, Hsin-hao Hsiao, Kendra B. Frederick +9 more
2007EMBO Journal63 citations Open access
Semantic Scholar
Structural and Kinetic Analyses of Macrophage Migration Inhibitory Factor (MIF) Active Site Interactions
G. Crichlow, J. Lubetsky, L. Leng, R. Bucala +1 more
2009Biochemistry57 citations Open access
Semantic Scholar
Inhibition of class C beta-lactamases: structure of a reaction intermediate with a cephem sulfone.
G. Crichlow, M. Nukaga, V. Doppalapudi, J. Buynak +1 more
2001Biochemistry57 citations
Semantic Scholar
Alternative Chemical Modifications Reverse the Binding Orientation of a Pharmacophore Scaffold in the Active Site of Macrophage Migration Inhibitory Factor*
G. Crichlow, Kai F. Cheng, Darrin R. Dabideen, M. Ochani +5 more
2007Journal of Biological Chemistry54 citations Open access
Semantic Scholar
Structural Interactions Dictate the Kinetics of Macrophage Migration Inhibitory Factor Inhibition by Different Cancer-Preventive Isothiocyanates
G. Crichlow, C. Fan, C. Keeler, M. Hodsdon +1 more
2012Biochemistry32 citations Open access
Semantic Scholar
Structure of an extended-spectrum class A beta-lactamase from Proteus vulgaris K1.
M. Nukaga, K. Mayama, G. Crichlow, J. Knox
2002Journal of Molecular Biology15 citations
Semantic Scholar
Crystallization and preliminary X-ray study of OXA-1, a class D β-lactamase
T. Sun, M. Nukaga, K. Mayama, G. Crichlow +2 more
20019 citations
Semantic Scholar
Unraveling the mechanism of recognition of the 3’ splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60
Hsin-hao Hsiao, G. Crichlow, J. Murphy, E. Folta-Stogniew +2 more
2020PLoS ONE6 citations Open access
Semantic Scholar
AV411 (Ibudilast) and AV1013 are non-competitive inhibitors of macrophage migration inhibitory factor: a novel induced-fit allosteric inhibition mechanism (133.11)
Yoonsang Cho, G. Crichlow, Jon J. Vermeire, L. Leng +8 more
2010Journal of Immunology1 citations
Semantic Scholar
Ternary Complex of Macrophage Migration Inhibitory Factor (MIF) Bound Both to 4-hydroxyphenylpyruvate and to the Allosteric Inhibitor AV1013 (R-stereoisomer)
G. Crichlow, Y. Cho, E. Lolis
20101 citations
Semantic Scholar
RCSB PDB AI Help Desk: retrieval-augmented generation for protein structure deposition support
Vivek Reddy Chithari, Jasmine Y. Young, Irina Persikova, Yu-He Liang +8 more
2026Bioinformatics Advances0 citations Open access
Semantic Scholar
Identification of a key water molecule involved in the macrophage migration inhibitory factor‐catalyzed tautomerization of para‐hydroxyphenylpyruvate using neutron crystallography
Gabriela C. Schröder, G. Crichlow, Ewelina Jablonowski, Georgios Pantouris +4 more
2026Protein Science0 citations Open access
Semantic Scholar
Getting to the Heart of the Matter—Social Determinants of Health, Behaviour Change, and Cardiovascular Disease: A Phenomenological Study
G. Crichlow, S. Sibbald
2025CJC Open0 citations Open access
Semantic Scholar
Growing the PDB Core Archive using ORCiD login for depositing 3D biostructures with OneDep
G. Crichlow, Zu-Kang Feng, Yu-He Liang, Erza Peisach +4 more
2023Acta Crystallographica Section A: Foundations and Advances0 citations
Semantic Scholar
Abstract 2643: Design and discovery of novel oral INV-88 macrophage migration inhibitory factor (MIF) inhibitors: Potent anti-tumor activity in vitro and in vivo
A. Gaweco, V. Chung, J. Tilley, William Windsor +5 more
2022Cancer Research0 citations
Semantic Scholar
The life and times of the PDB format – looking towards the future with mmCIF
G. Crichlow, C. Lawson, Johnathan H. Westbrook, S. Burley +9 more
2021Acta Crystallographica Section A: Foundations and Advances0 citations Open access
Semantic Scholar
Crystal Structure of the Two Tandem RRM Domains of PUF60 Bound to a Modified AdML Pre-mRNA 3' Splice Site Analogue
G. Crichlow, Hsin-hao Hsiao, R. Albright, E. Lolis +1 more
20170 citations
Semantic Scholar
Two Tandem RRM Domains of PUF60 Bound to an AdML Pre-mRNA 3' Splice Site Analogue with a Modified Binding-Site Nucleic Acid Base
G. Crichlow, Hsin-hao Hsiao, R. Albright, E. Lolis +1 more
20170 citations
Semantic Scholar
CRYSTAL STRUCTURE OF THE TWO TANDEM RRM DOMAINS OF PUF60 BOUND TO A PORTION OF AN ADML PRE-MRNA 3' SPLICE SITE ANALOG
Hsin-hao Hsiao, G. Crichlow, R. Albright, J. Murphy +2 more
20170 citations
Semantic Scholar
Two Tandem RRM Domains of FBP-Interacting Repressor (FIR), also Known as PUF60
G. Crichlow, Yuande Yang, Hongwen Zhou, E. Lolis +1 more
20170 citations
Semantic Scholar
1.55 A Crystal Structure of Macrophage Migration Inhibitory Factor bound to ISO-66 and a related compound
G. Crichlow, Y. Al-Abed, E. Lolis
20140 citations
Semantic Scholar
Macrophage Migration Inhibitory Factor (MIF) with Covalently Bound L-sulforaphane
G. Crichlow, E. Lolis
20120 citations
Semantic Scholar
Phenethylisothiocyanate Covalently Bound to Macrophage Migration Inhibitory Factor (MIF)
G. Crichlow, E. Lolis
20120 citations
Semantic Scholar
Corrections BIOPHYSICS AND COMPUTATIONAL BIOLOGY Correction for “ Protein crystallization facilitated by molecularly imprinted polymers
E. Saridakis, S. Khurshid, L. Govada, Quan T Phan +13 more
20110 citations
Semantic Scholar
Crystal structure of CXCL12
J. Murphy, E. Lolis, Yong Xiong, H. Yuan +1 more
20100 citations
Semantic Scholar
Macrophage Migration Inhibitory Factor (MIF) Bound to the (R)-Stereoisomer of AV1013
G. Crichlow, Yoonsang Cho, E. Lolis
20100 citations
Semantic Scholar
CXCL12 (SDF) in trigonal space group
J. Murphy, G. Crichlow, E. Lolis
20100 citations
Semantic Scholar
Macrophage Migration Inhibitory Factor (MIF) complexed with Inhibitor, 4-IPP.
S. Zierow, G. Crichlow, E. Lolis
20080 citations
Semantic Scholar
Crystal Structure of Macrophage Migration Inhibitory Factor Bound to an Acetaminophen Dimer Derived from NAPQI
G. Crichlow, E. Lolis
20080 citations
Semantic Scholar
Structure of Macrophage Migration Inhibitory Factor Covalently Inhibited by PMSF Treatment
G. Crichlow, E. Lolis
20080 citations
Semantic Scholar
Crystal Structure of First Two RRM Domains of FIR Bound to ssDNA from a Portion of FUSE
G. Crichlow, Yuande Yang, C. Fan, E. Lolis +1 more
20080 citations
Semantic Scholar
Macrophage Migration Inhibitory Factor (MIF) at 1.25 A Resolution
G. Crichlow, E. Lolis
20080 citations
Semantic Scholar
MIF Bound to a Fluorinated OXIM Derivative
G. Crichlow, Y. Al-Abed, E. Lolis
20070 citations
Semantic Scholar
Structural Studies of MIF
E. Lolis, G. Crichlow
20070 citations
Semantic Scholar
Macrophage Migration Inhibitory Factor (MIF) Complexed with OXIM6 (an OXIM Derivative Not Containing a Ring in its R-group)
G. Crichlow, Y. Al-Abed, E. Lolis
20070 citations
Semantic Scholar
Crystal Structure of MIF bound to a Novel Inhibitor, OXIM-11
G. Crichlow, Y. Al-Abed, E. Lolis
20070 citations
Semantic Scholar
Structural basis of activity and mechanism of class C beta-lactamases
G. Crichlow
20020 citations
Semantic Scholar
STRUCTURE OF CLASS A CEPHALOSPORINASE FROM PROTEUS VULGARIS K1
M. Nukaga, G. Crichlow, A. P. Kuzin, K. Mayama +1 more
20020 citations
Semantic Scholar
STRUCTURE OF THE E. CLOACAE GC1 BETA-LACTAMASE WITH A CEPHALOSPORIN SULFONE INHIBITOR
G. Crichlow, M. Nukaga, J. Buynak, J. Knox
20010 citations
Semantic Scholar
STRUCTURE OF THE BETA-LACTAMASE OF ENTEROBACTER CLOACAE GC1
G. Crichlow, A. P. Kuzin, M. Nukaga, T. Sawai +1 more
19990 citations
Semantic Scholar

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