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M. Curran · SciRah

Researcher profile · Semantic Scholar

M. Curran

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M. Curran — researcher profile on SciRah

h-index: 20
Works: 48
Citations: 1,675

Most-cited papers

A functional genomics predictive network model identifies regulators of inflammatory bowel disease
Lauren A. Peters, J. Perrigoue, A. Mortha, A. Iuga +34 more
2017Nature Genetics230 citations Open access
Semantic Scholar
Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disorders
G. Wittenberg, A. Stylianou, Yun Zhang, Yu Sun +10 more
2019Molecular Psychiatry167 citations Open access
Semantic Scholar
Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related disease
M. Suarez-Farinas, M. Tokuyama, G. Wei, Ruiqi Huang +35 more
2020bioRxiv131 citations Open access
Semantic Scholar
Variants in TRIM22 that Affect NOD2 Signaling Are Associated With Very Early Onset Inflammatory Bowel Disease
Qi Li, Cheng H. Lee, Lauren A. Peters, Lucas A. Mastropaolo +36 more
2016Gastroenterology111 citations Open access
Semantic Scholar
A biopsy and blood based molecular biomarker of inflammation in inflammatory bowel disease
C. Argmann, Ruixue Hou, R. Ungaro, H. Irizar +31 more
2022Gut102 citations Open access
Semantic Scholar
Assessment of Belatacept-Mediated Costimulation Blockade Through Evaluation of CD80/86-Receptor Saturation
R. Latek, Catherine A. Fleener, V. Lamian, E. Kulbokas +5 more
2009Transplantation98 citations Open access
Semantic Scholar
The effects of interleukin-6 neutralizing antibodies on symptoms of depressed mood and anhedonia in patients with rheumatoid arthritis and multicentric Castleman's disease.
Yu Sun, Dai Wang, G. Salvadore, B. Hsu +8 more
2017Brain, behavior, and immunity91 citations
Semantic Scholar
Challenges in IBD Research: Precision Medicine.
L. Denson, M. Curran, D. McGovern, Walter A. Koltun +14 more
2019Inflammatory Bowel Diseases84 citations Open access
Semantic Scholar
Integrative analysis of the Inflammatory Bowel Disease serum metabolome improves our understanding of genetic etiology and points to novel putative therapeutic targets
A. Di Narzo, S. Houten, R. Kosoy, Rui-Qi Huang +25 more
2021Gastroenterology75 citations Open access
Semantic Scholar
Integrative genomic deconvolution of rheumatoid arthritis GWAS loci into gene and cell type associations
A. Walsh, J. Whitaker, C. C. Huang, Y. Cherkas +4 more
2016Genome Biology69 citations Open access
Semantic Scholar
Gene Expression Signature for Prediction of Golimumab Response in a Phase 2a Open-Label Trial of Patients With Ulcerative Colitis.
S. Telesco, C. Brodmerkel, Hong-Yan Zhang, L. Kim +17 more
2018Gastroenterology63 citations Open access
Semantic Scholar
Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study
P. Silkoff, I. Strâmbu, M. Laviolette, David Singh +24 more
2015Respiratory Research59 citations Open access
Semantic Scholar
HLA-C*06:02 Allele and Response to IL-12/23 Inhibition: Results from the Ustekinumab Phase 3 Psoriasis Program.
Katherine Li, C. C. Huang, B. Randazzo, Shu Li +4 more
2016Journal of Investigative Dermatology56 citations Open access
Semantic Scholar
Modular Analysis of Peripheral Blood Gene Expression in Rheumatoid Arthritis Captures Reproducible Gene Expression Changes in TNF Responders
M. Oswald, M. Curran, S. Lamberth, R. Townsend +9 more
2015Arthritis & Rheumatology47 citations Open access
Semantic Scholar
Blood and Intestine eQTLs from an Anti-TNF-Resistant Crohn's Disease Cohort Inform IBD Genetic Association Loci
A. Di Narzo, Lauren A. Peters, C. Argmann, A. Stojmirović +12 more
2016Clinical and Translational Gastroenterology45 citations Open access
Semantic Scholar
Autoimmune Disease–Associated Haplotypes of BLK Exhibit Lowered Thresholds for B Cell Activation and Expansion of Ig Class‐Switched B Cells
Kim R. Simpfendorfer, Brandon E. Armstead, A. Shih, Wen-Tian Li +5 more
2015Arthritis & Rheumatology41 citations
Semantic Scholar
Levels of circulating MMP-7 degraded elastin are elevated in pulmonary disorders.
J. H. Kristensen, Lise Larsen, B. Dasgupta, C. Brodmerkel +10 more
2015Clinical Biochemistry36 citations
Semantic Scholar
Deep Analysis of the Peripheral Immune System in IBD Reveals New Insight in Disease Subtyping and Response to Monotherapy or Combination Therapy
R. Kosoy, S. Kim-Schulze, A. Rahman, Joshua R. Friedman +19 more
2021Cellular and Molecular Gastroenterology and Hepatology33 citations Open access
Semantic Scholar
Molecular Characterization of Limited Ulcerative Colitis Reveals Novel Biology and Predictors of Disease Extension
C. Argmann, M. Tokuyama, R. Ungaro, Rui-Qi Huang +25 more
2021Gastroenterology26 citations Open access
Semantic Scholar
A serological marker of the N-terminal neoepitope generated during LOXL2 maturation is elevated in patients with cancer or idiopathic pulmonary fibrosis
D. J. Leeming, N. Willumsen, J. Sand, S. Nielsen +5 more
2018Biochemistry and Biophysics Reports24 citations Open access
Semantic Scholar
Posttransplantation diabetes mellitus in heart transplant recipients.
J. Ladowski, R. Kormos, B. Uretsky, A. Lee +5 more
1989The Journal of heart transplantation19 citations
Semantic Scholar
SAT0182 Improvement in Measures of Depressed Mood and Anhedonia, and Fatigue, In a Randomized, Placebo-Controlled, Phase 2 Study of Sirukumab, A Human Anti-Interleukin-6 Antibody, In Patients with Rheumatoid Arthritis
B. Hsu, D. Wang, Yu Sun, G. Salvadore +6 more
201515 citations
Semantic Scholar
Comprehensive analysis of treatment response phenotypes in rheumatoid arthritis for pharmacogenetic studies
K. Standish, Conway C. Huang, M. Curran, N. Schork
2017Arthritis Research & Therapy12 citations Open access
Semantic Scholar
Group-based variant calling leveraging next-generation supercomputing for large-scale whole-genome sequencing studies
K. Standish, Tristan M. Carland, Glenn K. Lockwood, W. Pfeiffer +10 more
2015BMC Bioinformatics12 citations Open access
Semantic Scholar
A Phase 2b, Randomized, Double-blind, Placebo-controlled, Parallel-arm, Multicenter Study Evaluating the Safety and Efficacy of Tesnatilimab in Patients With Moderately to Severely Active Crohn's Disease.
M. Allez, B. Sands, B. Feagan, G. D'Haens +11 more
2023Journal of Crohn's & Colitis8 citations Open access
Semantic Scholar
A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients
Lauren A. Peters, Joshua R. Friedman, A. Stojmirović, J. Hagen +14 more
2023Communications Biology8 citations Open access
Semantic Scholar
Conference Scene: Diagnostics and personalized medicine: observations from the World Companion Diagnostics Summit
M. Curran, S. Platero
20113 citations Open access
Semantic Scholar
300. Improvement in Measures of Depressed Mood and Anhedonia in Two Randomized, Placebo-Controlled Phase III Studies of Sirukumab, a Human Anti-Interleukin-6 Antibody, in Patients with Rheumatoid Arthritis
Yu Sun, G. Wittenberg, Guang Chen, W. Drevets +2 more
20172 citations
Semantic Scholar
THU0130 Improvement in measures of depressed mood and anhedonia in two randomized, placebo-controlled phase iii studies of sirukumab, a human anti-interleukin-6 antibody, in patients with rheumatoid arthritis
Yu Sun, B. Hsu, D. Wang, M. Curran +3 more
20172 citations Open access
Semantic Scholar
Neutrophil elastase degraded elastin is elevated in serum of idiopathic pulmonary fibrosis
J. H. Kristensen, B. Dasgupta, J. Sand, C. Brodmerkel +3 more
2014European Respiratory Journal2 citations
Semantic Scholar
THU0105 Effect of sirukumab on hepcidin levels and markers of anemia: Results of a phase 2B trial in patients with active rheumatoid arthritis despite methotrexate therapy
G. Toedter, S. Sague, X. Wu, M. Curran +1 more
20132 citations
Semantic Scholar
Prediction of Non-Response to Anti-Tnf Therapy in Ulcerative Colitis: Implications for Patient Stratification for IBD Trials and Novel Treatment Paradigms
S. Telesco, L. Greenbaum, Hong-Yan Zhang, R. Mazumder +9 more
20171 citations
Semantic Scholar
FRI0009 Serum 14-3-3 ETA Is An RA Specific Mechanistic Marker
B. Dasgupta, Y. Cherkas, S. Lamberth, K. Hayden +3 more
20161 citations
Semantic Scholar
P.2.h.016 Interleukin-6 antibody Sirukumab improves depressive symptoms in a randomized, placebo-controlled, phase 2 study in patients with rheumatoid arthritis
D. Wang, Yu Sun, G. Salvadore, Jaskaran Singh +6 more
20151 citations
Semantic Scholar
Reply
Peter K. Gregersen, M. Oswald, M. Curran, John Carulli
2015Arthritis & Rheumatology1 citations
Semantic Scholar
FRI0271 Modular Analysis of Peripheral Blood Gene Expression in Rheumatoid Arthritis Captures Reproducible Gene Expression Changes in TNF Responders
M. Curran, M. Oswald, Annette Lee, Y. Cherkas +3 more
20141 citations
Semantic Scholar
OP36 A colonic gene expression signature predicts non-response to anti-inflammatory therapies in inflammatory bowel disease
Takahiro Sato, Katherine Li, K. Hayden, L. Tomsho +8 more
2019Journal of Crohn's & Colitis0 citations
Semantic Scholar
DOP012 Disease demarcation in ulcerative colitis is associated with different patterns of gene expression
M. Suárez-Fariñas, Rui-Qi Huang, R. Kosoy, A. Irizar +28 more
20180 citations
Semantic Scholar
P849 Genetic variation within the NKG2D pathway may influence the response to anti-NKG2D therapy in Crohn’s disease
A. Hart, E. Neiman, J. Perrigoue, L.-Y. Hao +9 more
20180 citations
Semantic Scholar
Tu1802 - Disease Demarcation in Ulcerative Colitis is Associated with Different Patterns of Gene Expression
M. Suárez-Fariñas, Rui-Qi Huang, R. Kosoy, A. Irizar +28 more
20180 citations
Semantic Scholar
Comparison of Conventional Chemical Method to Immunochemical Method for Faecal Occult Blood Testing
P. Cirillo, N. Lopes, C. Bustamante, A. Morais +14 more
20170 citations
Semantic Scholar
A neo-epitope of serum lysyl oxidase like 2 (LOXL2) generated during enzyme maturation is elevated in cancer and idiopathic pulmonary disease
D. Leeming, C. Bager, N. Willumsen, J. Sand +4 more
20170 citations
Semantic Scholar
Su1858 Integrative Networks Identify Novel Regulators of Susceptibility and Pathogenesis of Inflammatory Bowel Disease
Lauren A. Peters, J. Perrigoue, A. Mortha, A. Stojmirović +31 more
20160 citations
Semantic Scholar
OP0027 Identification of Molecular Disease Drivers Using eQTLS Derived from a Cohort of Rheumatoid Arthritis Patients
A. Walsh, J. Whitaker, Conway C. Huang, Y. Cherkas +4 more
20150 citations
Semantic Scholar
Clinical biomarkers identify T-helper 2 status defined by mucosal CCL26 in the ADEPT-asthma study
M. Loza, I. Strâmbu, M. Laviolette, D. Singh +25 more
20150 citations
Semantic Scholar
FRI0038 Pharmacodynamic Effect of Intravenous Golimumab by Messenger RNA Expression Profiling
Y. Cherkas, Carrie Brodmerkel, M. Curran, S. Lamberth
20140 citations
Semantic Scholar
MMP7-degraded elastin is elevated in serum of patients with idiopathic pulmonary fibrosis
J. Sand, J. H. Kristensen, B. Dasgupta, M. Curran +3 more
2014European Respiratory Journal0 citations
Semantic Scholar
SAT0009 Utility of VECTRA-DA™ on Assessment Of Rheumatoid Arthritis Disease Activity and Golimumab Response: Results of a Pilot Study from a Phase 3 Trial in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy
S. Lamberth, Y. Cherkas, Carrie Brodmerkel, M. Curran
20130 citations
Semantic Scholar

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