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A. Nishiyama · SciRah

Researcher profile · Semantic Scholar

A. Nishiyama

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A. Nishiyama — researcher profile on SciRah

h-index: 33
Works: 84
Citations: 6,126

Most-cited papers

AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1.
K. Hirota, M. Matsui, S. Iwata, A. Nishiyama +2 more
1997Proceedings of the National Academy of Sciences of the United States of America872 citations Open access
Semantic Scholar
Identification of Thioredoxin-binding Protein-2/Vitamin D3 Up-regulated Protein 1 as a Negative Regulator of Thioredoxin Function and Expression*
A. Nishiyama, M. Matsui, S. Iwata, Kiichi Hirota +6 more
1999Journal of Biological Chemistry766 citations Open access
Semantic Scholar
Zscan4 regulates telomere elongation and genomic stability in ES cells
Michal Zalzman, Geppino Falco, Lioudmila V. Sharova, A. Nishiyama +8 more
2010Nature425 citations Open access
Semantic Scholar
Brd4 marks select genes on mitotic chromatin and directs postmitotic transcription.
Anup Dey, A. Nishiyama, T. Karpova, James G. McNally +1 more
2009Molecular Biology of the Cell321 citations Open access
Semantic Scholar
Thioredoxin‐2 (TRX‐2) is an essential gene regulating mitochondria‐dependent apoptosis
Toru Tanaka, F. Hosoi, Y. Yamaguchi-Iwai, Hajime Nakamura +7 more
2002EMBO Journal312 citations Open access
Semantic Scholar
Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation.
D. Kurotaki, N. Osato, A. Nishiyama, Michio Yamamoto +9 more
2013Blood250 citations Open access
Semantic Scholar
The Bromodomain Protein Brd4 Stimulates G1 Gene Transcription and Promotes Progression to S Phase*
Kazuki Mochizuki, A. Nishiyama, M. Jang, Anup Dey +5 more
2008Journal of Biological Chemistry238 citations Open access
Semantic Scholar
Redox control of resistance to cis-diamminedichloroplatinum (II) (CDDP): protective effect of human thioredoxin against CDDP-induced cytotoxicity.
T. Sasada, S. Iwata, N. Sato, Y. Kitaoka +6 more
1996Journal of Clinical Investigation212 citations Open access
Semantic Scholar
Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity.
Satoru Matsuda, J. Kawamura-Tsuzuku, Miho Ohsugi, M. Yoshida +6 more
1996Oncogene204 citations
Semantic Scholar
Uncovering early response of gene regulatory networks in ES cells by systematic induction of transcription factors
A. Nishiyama, Li Xin, A. Sharov, Marshall P. Thomas +29 more
2009Cell Stem Cell191 citations Open access
Semantic Scholar
Redox Regulation by Thioredoxin and Thioredoxin‐Binding Proteins
A. Nishiyama, H. Masutani, H. Nakamura, Yumiko Nishinaka +1 more
2001IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology165 citations
Semantic Scholar
Redox regulation by thioredoxin superfamily; protection against oxidative stress and aging
Toru Tanaka, H. Nakamura, A. Nishiyama, F. Hosoi +3 more
2000Free radical research160 citations
Semantic Scholar
Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction
H. Konishi, Takayuki Okamoto, Yuichiro Hara, Okiru Komine +16 more
2020EMBO Journal157 citations Open access
Semantic Scholar
IRF8 inhibits C/EBPα activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils
D. Kurotaki, Michio Yamamoto, A. Nishiyama, K. Uno +9 more
2014Nature Communications145 citations Open access
Semantic Scholar
Toll-Like Receptor 9 Signaling Activates NF-κB through IFN Regulatory Factor-8/IFN Consensus Sequence Binding Protein in Dendritic Cells1
H. Tsujimura, T. Tamura, H. Kong, A. Nishiyama +3 more
2004Journal of Immunology142 citations Open access
Semantic Scholar
Loss of Thioredoxin-Binding Protein-2/Vitamin D3 Up-Regulated Protein 1 in Human T-Cell Leukemia Virus Type I-Dependent T-Cell Transformation
Yumiko Nishinaka, A. Nishiyama, H. Masutani, S. Oka +6 more
2004Cancer Research130 citations Open access
Semantic Scholar
BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses
Anup Dey, Wenjing Yang, A. Gégonne, A. Nishiyama +9 more
2019EMBO Journal113 citations Open access
Semantic Scholar
Lyn Kinase Suppresses the Transcriptional Activity of IRF5 in the TLR-MyD88 Pathway to Restrain the Development of Autoimmunity.
T. Ban, Go R. Sato, A. Nishiyama, Ai Akiyama +18 more
2016Immunity106 citations Open access
Semantic Scholar
Shared and Distinct Functions of the Transcription Factors IRF4 and IRF8 in Myeloid Cell Development
Michio Yamamoto, Takayuki Kato, C. Hotta, A. Nishiyama +10 more
2011PLoS ONE92 citations Open access
Semantic Scholar
Change of redox status and modulation by thiol replenishment in retinal photooxidative damage.
M. Tanito, A. Nishiyama, Toru Tanaka, H. Masutani +3 more
2002Investigative Ophthalmology and Visual Science89 citations
Semantic Scholar
Dax1 Binds to Oct3/4 and Inhibits Its Transcriptional Activity in Embryonic Stem Cells
Chuan-Hai Sun, Yuhki Nakatake, Tadayuki Akagi, Hiroki Ura +6 more
2009Molecular and Cellular Biology84 citations Open access
Semantic Scholar
Inducible Deposition of the Histone Variant H3.3 in Interferon-stimulated Genes*
T. Tamura, Matthew Smith, T. Kanno, H. Dasenbrock +2 more
2009Journal of Biological Chemistry83 citations Open access
Semantic Scholar
Brd4 is required for recovery from antimicrotubule drug-induced mitotic arrest: preservation of acetylated chromatin.
A. Nishiyama, Anup Dey, J. Miyazaki, K. Ozato
2005Molecular Biology of the Cell79 citations Open access
Semantic Scholar
Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells.
Haruka Sasaki, D. Kurotaki, N. Osato, Hideaki Sato +10 more
2015Blood66 citations Open access
Semantic Scholar
Systematic repression of transcription factors reveals limited patterns of gene expression changes in ES cells
A. Nishiyama, A. Sharov, Y. Piao, Misa Amano +25 more
2013Scientific Reports65 citations Open access
Semantic Scholar
Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease
T. Ban, M. Kikuchi, Go R. Sato, Akio Manabe +18 more
2021Nature Communications62 citations Open access
Semantic Scholar
Biallelic TBCD Mutations Cause Early-Onset Neurodegenerative Encephalopathy.
N. Miyake, R. Fukai, Chihiro Ohba, Takahiro Chihara +29 more
2016American Journal of Human Genetics60 citations Open access
Semantic Scholar
A RUNX–CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes
Koichi Murakami, Haruka Sasaki, A. Nishiyama, D. Kurotaki +9 more
2021Nature Immunology53 citations
Semantic Scholar
Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors.
D. Kurotaki, J. Nakabayashi, A. Nishiyama, Haruka Sasaki +7 more
2018Cell Reports52 citations Open access
Semantic Scholar
Generation of mouse ES cell lines engineered for the forced induction of transcription factors
Lina S. Correa-Cerro, Y. Piao, A. Sharov, A. Nishiyama +15 more
2011Scientific Reports51 citations Open access
Semantic Scholar
Epigenetic control of early dendritic cell lineage specification by the transcription factor IRF8 in mice.
D. Kurotaki, Wataru Kawase, Haruka Sasaki, J. Nakabayashi +5 more
2019Blood48 citations Open access
Semantic Scholar
The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis.
Naoki Ikeda, H. Kubota, Risa Suzuki, M. Morita +25 more
2023Cell Reports41 citations Open access
Semantic Scholar
Defining developmental potency and cell lineage trajectories by expression profiling of differentiating mouse embryonic stem cells
Kazuhiro Aiba, Timur Nedorezov, Y. Piao, A. Nishiyama +6 more
2008DNA Research36 citations Open access
Semantic Scholar
BRD4 regulates adiponectin gene induction by recruiting the P-TEFb complex to the transcribed region of the gene
Naoko Sakurai, Yuko Inamochi, Takuya Inoue, Natsuyo Hariya +8 more
2017Scientific Reports29 citations Open access
Semantic Scholar
MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis.
Y. Hayashi, K. Kawabata, Yosuke Tanaka, Yasufumi Uehara +28 more
2022Cell Reports26 citations Open access
Semantic Scholar
Chromatin structure undergoes global and local reorganization during murine dendritic cell development and activation
D. Kurotaki, Kenta Kikuchi, Kai-Rong Cui, Wataru Kawase +8 more
2022Proceedings of the National Academy of Sciences of the United States of America22 citations Open access
Semantic Scholar
Single-cell transcriptomes underscore genetically distinct tumor characteristics and microenvironment for hereditary kidney cancers
Ryosuke Jikuya, Koichi Murakami, A. Nishiyama, I. Kato +34 more
2022iScience19 citations Open access
Semantic Scholar
Generation and gene expression profiling of 48 transcription-factor-inducible mouse embryonic stem cell lines
K. Yamamizu, A. Sharov, Y. Piao, Misa Amano +5 more
2016Scientific Reports18 citations Open access
Semantic Scholar
SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline
Toshiaki Ito, Atsuki Osada, M. Ohta, Kana Yokota +5 more
2021Scientific Reports17 citations Open access
Semantic Scholar
Intracellular delivery of acetyl‐histone peptides inhibits native bromodomain–chromatin interactions and impairs mitotic progression
A. Nishiyama, Kazuki Mochizuki, F. Mueller, T. Karpova +2 more
2008FEBS Letters17 citations Open access
Semantic Scholar
The transcription factor IRF8 counteracts BCR-ABL to rescue dendritic cell development in chronic myelogenous leukemia.
Tomoya Watanabe, C. Hotta, S. Koizumi, Kazuho Miyashita +13 more
2013Cancer Research15 citations Open access
Semantic Scholar
Biochemical and cellular effects of electrophiles present in ambient air samples
N. Iwamoto, A. Nishiyama, A. Eiguren-Fernandez, W. Hinds +4 more
201015 citations
Semantic Scholar
Activation of JNK Triggers Release of Brd4 from Mitotic Chromosomes and Mediates Protection from Drug-Induced Mitotic Stress
A. Nishiyama, Anup Dey, T. Tamura, M. Ko +1 more
2012PLoS ONE14 citations Open access
Semantic Scholar
Responsiveness of genes to manipulation of transcription factors in ES cells is associated with histone modifications and tissue specificity
A. Sharov, A. Nishiyama, Y. Piao, L. Correa-Cerro +4 more
2011BMC Genomics12 citations Open access
Semantic Scholar
Transcription elongation factor Brd4-P-TEFb accelerates intestinal differentiation-associated SLC2A5 gene expression
Yuko Inamochi, Anup Dey, A. Nishiyama, T. Kubota +3 more
2016Biochemistry and Biophysics Reports11 citations Open access
Semantic Scholar
C-propeptide region of human pro α 1 type 1 collagen interacts with thioredoxin
Ken Matsumoto, H. Masutani, A. Nishiyama, S. Hashimoto +3 more
200210 citations
Semantic Scholar
Compromised anti-tumor–immune features of myeloid cell components in chronic myeloid leukemia patients
Ibuki Harada, Haruka Sasaki, Koichi Murakami, A. Nishiyama +15 more
2021Scientific Reports8 citations Open access
Semantic Scholar
Chromatin Properties of Regulatory DNA Probed by Manipulation of Transcription Factors
A. Sharov, A. Nishiyama, Yong Qian, D. Dudekula +3 more
2014J. Comput. Biol.5 citations Open access
Semantic Scholar
Redox Regulation of Gene Expression and Transcription Factors in Response to Environmental Oxidants
H. Masutani, A. Nishiyama, Yongwon Kwon, Yong-chul Kim +2 more
20015 citations
Semantic Scholar
C-propeptide region of human pro alpha 1 type 1 collagen interacts with thioredoxin.
Ken Matsumoto, H. Masutani, A. Nishiyama, S. Hashimoto +3 more
2002Biochemical and Biophysical Research Communications - BBRC4 citations
Semantic Scholar

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T. Tamura×22
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T. Tamura — researcher profile on SciRah
K. Ozato×19
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J. Yodoi×10
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D. Kurotaki×10
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H. Masutani — researcher profile on SciRah

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M. Ko — researcher profile on SciRah

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J. Nakabayashi×7

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Haruka Sasaki×6

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Haruka Sasaki — researcher profile on SciRah

Hajime Nakamura×5

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Lioudmila V. Sharova×5

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Lioudmila V. Sharova — researcher profile on SciRah