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M. Alexandrow · SciRah

Researcher profile · Semantic Scholar

M. Alexandrow

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M. Alexandrow — researcher profile on SciRah

h-index: 20
Works: 40
Citations: 1,732

Most-cited papers

Transforming Growth Factor β and Cell Cycle Regulation
M. Alexandrow, H. Moses
1995341 citations
Semantic Scholar
Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.
M. Alexandrow, M. Kawabata, M. Aakre, H. Moses
1995Proceedings of the National Academy of Sciences of the United States of America149 citations Open access
Semantic Scholar
Chromatin decondensation in S-phase involves recruitment of Cdk2 by Cdc45 and histone H1 phosphorylation
M. Alexandrow, J. Hamlin
2005Journal of Cell Biology132 citations Open access
Semantic Scholar
Curcumin: A Novel Stat 3 Pathway Inhibitor for Chemoprevention of Lung Cancer
M. Alexandrow, Lan-Xi Song, S. Altiok, J. Gray +2 more
2012European Journal of Cancer Prevention113 citations Open access
Semantic Scholar
The Chk1-mediated S-phase Checkpoint Targets Initiation Factor Cdc45 via a Cdc25A/Cdk2-independent Mechanism*
Peijun Liu, L. R. Barkley, Tovah A. Day, X. Bi +4 more
2006Journal of Biological Chemistry107 citations Open access
Semantic Scholar
Transforming growth factor beta and cell cycle regulation.
M. Alexandrow, H. Moses
1995Cancer Research98 citations
Semantic Scholar
Cdc45 Limits Replicon Usage from a Low Density of preRCs in Mammalian Cells
Philip G. Wong, S. Winter, E. Zaika, Thinh V. Cao +4 more
2011PLoS ONE93 citations Open access
Semantic Scholar
Cdc6 Chromatin Affinity Is Unaffected by Serine-54 Phosphorylation, S-Phase Progression, and Overexpression of Cyclin A
M. Alexandrow, J. Hamlin
2004Molecular and Cellular Biology82 citations Open access
Semantic Scholar
Cell Cycle Arrest by Transforming Growth Factor β1 near G1/S Is Mediated by Acute Abrogation of Prereplication Complex Activation Involving an Rb-MCM Interaction
Piyali Mukherjee, S. Winter, M. Alexandrow
2009Molecular and Cellular Biology76 citations Open access
Semantic Scholar
Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin
Philip G. Wong, M. Glozak, Thinh V. Cao, C. Vaziri +2 more
2010Cell Cycle74 citations Open access
Semantic Scholar
Transforming growth factor beta 1 inhibits mouse keratinocytes late in G1 independent of effects on gene transcription.
M. Alexandrow, H. Moses
1995Cancer Research66 citations
Semantic Scholar
Sulforaphane for the chemoprevention of bladder cancer: molecular mechanism targeted approach
A. Leone, G. Diorio, W. Sexton, M. Schell +3 more
2017OncoTarget58 citations Open access
Semantic Scholar
An evolutionary framework for treating pediatric sarcomas
D. Reed, Jonathan L. Metts, Mariyah Pressley, B. Fridley +10 more
2020Cancer49 citations Open access
Semantic Scholar
Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication
Wasia Rizwani, M. Alexandrow, S. Chellappan
2009Cell Cycle40 citations Open access
Semantic Scholar
A Potential Role for Mini-chromosome Maintenance (MCM) Proteins in Initiation at the Dihydrofolate Reductase Replication Origin*
M. Alexandrow, M. Ritzi, A. Pemov, J. Hamlin
2002Journal of Biological Chemistry34 citations Open access
Semantic Scholar
TGF beta regulation of cell proliferation.
Harold L. Moses, C. L. Arteaga, M. Alexandrow, Lina Dagnino +3 more
1994Princess Takamatsu symposia29 citations
Semantic Scholar
The CMG Helicase and Cancer: A Tumor ‘Engine’ and Weakness with Missing Mutations
Shengyan Xiang, D. Reed, M. Alexandrow
2022Oncogene27 citations Open access
Semantic Scholar
Suppression of Reserve MCM Complexes Chemosensitizes to Gemcitabine and 5-Fluorouracil
Victoria L. Bryant, Roy Elias, S. McCarthy, T. Yeatman +1 more
2015Molecular Cancer Research27 citations Open access
Semantic Scholar
Myc-driven chromatin accessibility regulates Cdc45 assembly into CMG helicases
Brook S. Nepon-Sixt, Victoria L. Bryant, M. Alexandrow
2019Communications Biology24 citations Open access
Semantic Scholar
Mammalian MCM Loading in Late-G1 Coincides with Rb Hyperphosphorylation and the Transition to Post-Transcriptional Control of Progression into S-Phase
Piyali Mukherjee, Thinh V. Cao, S. Winter, M. Alexandrow
2009PLoS ONE22 citations Open access
Semantic Scholar
Insig2 is associated with colon tumorigenesis and inhibits Bax-mediated apoptosis
Chang-Gong Li, M. Gruidl, S. Eschrich, S. McCarthy +3 more
2008International Journal of Cancer21 citations Open access
Semantic Scholar
Kips off to Myc: Implications for TGFβ signaling
M. Alexandrow, Harold L. Moses
199721 citations
Semantic Scholar
Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival
L. M. Alexander, January M. Watters, Jessica A. Reusch, M. Maurin +5 more
2017Molecular Immunology17 citations Open access
Semantic Scholar
The Chk 1-mediated S-phase Checkpoint Targets Initiation Factor Cdc 45 via a Cdc 25 A / Cdk 2-independent Mechanism *
Peijun Liu, L. R. Barkley, Tovah A. Day, X. Bi +4 more
200612 citations
Semantic Scholar
c‐Myc‐enhanced S phase entry in keratinocytes is associated with positive and negative effects on cyclin‐dependent kinases
M. Alexandrow, H. Moses
1998Journal of Cellular Biochemistry12 citations
Semantic Scholar
Phase II Randomized Study of Enzastaurin (LY317615) for Lung Cancer Prevention in Former Smokers
J. Gray, S. Altiok, M. Alexandrow, Frank W. Walsh +4 more
2012Cancer10 citations Open access
Semantic Scholar
Modeling phenotypic heterogeneity towards evolutionarily inspired osteosarcoma therapy
Darcy L Welch, Brooke L. Fridley, L. Cen, J. Teer +12 more
2023Scientific Reports9 citations Open access
Semantic Scholar
Myc and the Replicative CMG Helicase: The Creation and Destruction of Cancer
D. Reed, M. Alexandrow
2020Bioessays9 citations Open access
Semantic Scholar
The N Terminus of the Retinoblastoma Protein Inhibits DNA Replication via a Bipartite Mechanism Disrupted in Partially Penetrant Retinoblastomas
S. Borysov, Brook S. Nepon-Sixt, M. Alexandrow
2015Molecular and Cellular Biology9 citations Open access
Semantic Scholar
DNase I Chromatin Accessibility Analysis.
Brook S. Nepon-Sixt, M. Alexandrow
2019Bio-protocol8 citations Open access
Semantic Scholar
TGFß1 Cell Cycle Arrest Is Mediated by Inhibition of MCM Assembly in Rb-deficient Conditions
Brook S. Nepon-Sixt, M. Alexandrow
2018Molecular Cancer Research8 citations Open access
Semantic Scholar
Kips off to Myc: implications for TGF beta signaling.
M. Alexandrow, H. Moses
1997Journal of Cellular Biochemistry7 citations
Semantic Scholar
Chemoprevention Trial Feasibility Using Botanicals in Exceptionally High Risk Populations for Lung Cancer
Nagi B. Kumar, Gwen Quinn, M. Alexandrow, J. Gray +3 more
2014Journal of Clinical Trials6 citations Open access
Semantic Scholar
Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
Shengyan Xiang, Kendall C Craig, Xingju Luo, Darcy L Welch +5 more
2024Molecular Cancer Therapeutics5 citations Open access
Semantic Scholar
Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
Shengyan Xiang, Xingju Luo, D. Welch, D. Reed +1 more
2023Research Square2 citations Open access
Semantic Scholar
Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells
L. M. Alexander, January M. Watters, Jessica A. Reusch, M. Maurin +5 more
2017Data in Brief2 citations Open access
Semantic Scholar
In vivo chromatin decondensation assays: molecular genetic analysis of chromatin unfolding characteristics of selected proteins.
S. Winter, Philip G. Wong, M. Alexandrow
2009Methods in molecular biology2 citations
Semantic Scholar
Analysis of DNA replication associated chromatin decondensation: in vivo assay for understanding chromatin remodeling mechanisms of selected proteins.
S. Borysov, Victoria L. Bryant, M. Alexandrow
2015Methods in molecular biology1 citations
Semantic Scholar
Multidimensional LDCT Imaging Endpoints for a Randomized Pilot Phase II Trial of Curcumin and Omega-3 Fatty Acids for Lung Cancer Chemoprevention: Results of a Randomized Pilot Trial
Nagi B. Kumar, M. Schabath, M. Alexandrow, J. Gray +5 more
2026Cancers0 citations Open access
Semantic Scholar
Abstract 3519: The c-Myc oncogene over-activates dormant replication origins and sensitizes cancer cells to chemotherapy drugs
Victoria L. Bryant, M. Alexandrow
20140 citations
Semantic Scholar
Assessment of feasibility and willingness of former heavy smokers to participate in chemoprevention trials to prevent lung cancer.
Nagi B. Kumar, Gwen Quinn, T. Crocker, M. Alexandrow +5 more
20120 citations
Semantic Scholar
Final results of a chemoprevention trial with enzastaurin in former smokers.
J. Gray, Soner Altiok, M. Alexandrow, Frank W. Walsh +3 more
2011Journal of Clinical Oncology0 citations
Semantic Scholar
Chemoprevention with enzastaurin: First-year results.
J. Gray, Soner Altiok, M. Alexandrow, Frank W. Walsh +2 more
2009Journal of Clinical Oncology0 citations
Semantic Scholar
Chromatin Protocols
M. Alexandrow
2009Methods in Molecular Biology0 citations
Semantic Scholar
Transforming Growth Factor ÃŸlInhibits Mouse Keratinocytes Late in Independent of Effects on Gene Transcription1
M. Alexandrow, H. Moses
20060 citations
Semantic Scholar
Transforming Growth Factor fi and Cell Cycle Regulation'
M. Alexandrow, H. Moses, Cell CycleKineticsof
20060 citations
Semantic Scholar
Late-G1 effects of C-myc on TGF-beta-induced inhibition of mouse keratinocytes
M. Alexandrow, H. Moses
19950 citations
Semantic Scholar

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H. Moses×8
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H. Moses — researcher profile on SciRah
Brook S. Nepon-Sixt×6
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Nagi B. Kumar — researcher profile on SciRah

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Victoria L. Bryant×4

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Philip G. Wong×3

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