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C. Yengo · SciRah

Researcher profile · Semantic Scholar

C. Yengo

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C. Yengo — researcher profile on SciRah

h-index: 31
Works: 149
Citations: 2,933

Most-cited papers

Omecamtiv Mecarbil Enhances the Duty Ratio of Human β-Cardiac Myosin Resulting in Increased Calcium Sensitivity and Slowed Force Development in Cardiac Muscle*
Anja M. Swenson, Wanjian Tang, Cheavar A. Blair, Christopher M. Fetrow +4 more
2017Journal of Biological Chemistry96 citations Open access
Semantic Scholar
Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
Seham Ebrahim, Matthew R. Avenarius, M. Grati, J. Krey +15 more
2016Nature Communications77 citations Open access
Semantic Scholar
Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions
Raymond C. Merritt, Uri Manor, Felipe T. Salles, M. Grati +5 more
2012Current Biology66 citations Open access
Semantic Scholar
Direct measurements of the coordination of lever arm swing and the catalytic cycle in myosin V
Darshan V. Trivedi, Joseph M. Muretta, Anja M. Swenson, Jonathon P Davis +2 more
2015Proceedings of the National Academy of Sciences of the United States of America58 citations Open access
Semantic Scholar
Biological Nanomotors with a Revolution, Linear, or Rotation Motion Mechanism
Pei-Xuan Guo, H. Noji, C. Yengo, Zhengyi Zhao +1 more
2016Microbiology and Molecular Reviews55 citations Open access
Semantic Scholar
Dilated cardiomyopathy mutation E525K in human beta-cardiac myosin stabilizes the interacting-heads motif and super-relaxed state of myosin
D. Rasicci, P. Tiwari, Skylar M. L. Bodt, Rohini Desetty +4 more
2022bioRxiv35 citations Open access
Semantic Scholar
Magnesium Modulates Actin Binding and ADP Release in Myosin Motors*
Anja M. Swenson, Darshan V. Trivedi, A. Rauscher, Yuan Wang +5 more
2014Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Myosin 3A Kinase Activity Is Regulated by Phosphorylation of the Kinase Domain Activation Loop*
Omar A. Quintero, William C. T. Unrath, S. Stevens, Uri Manor +2 more
2013Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Switch II mutants reveal coupling between the nucleotide- and actin-binding regions in myosin V.
Darshan V. Trivedi, Charles C. David, D. Jacobs, C. Yengo
2012Biophysical Journal32 citations Open access
Semantic Scholar
Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Haiyang Liu, Jian-Chao Li, M. H. Raval, N. Yao +8 more
2016eLife30 citations Open access
Semantic Scholar
Characterization of a novel MYO3A missense mutation associated with a dominant form of late onset hearing loss
V. Dantas, M. H. Raval, A. Ballesteros, Runjia Cui +10 more
2018Scientific Reports28 citations Open access
Semantic Scholar
Single-cell analysis reveals differential regulation of the alveolar macrophage actin cytoskeleton by surfactant proteins A1 and A2: implications of sex and aging
Nikolaos Tsotakos, D. S. Phelps, C. Yengo, V. Chinchilli +1 more
2016Biology of Sex Differences25 citations Open access
Semantic Scholar
Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin
M. Doran, M. Rynkiewicz, David Rasicci, Skylar M. L. Bodt +5 more
2022bioRxiv23 citations Open access
Semantic Scholar
FRET and optical trapping reveal mechanisms of actin-activation of the power stroke and phosphate-release in myosin V.
Laura K. Gunther, John A. Rohde, Wanjian Tang, Joseph A. Cirilo +5 more
2020Journal of Biological Chemistry23 citations Open access
Semantic Scholar
Structure of the MORN4/Myo3a Tail Complex Reveals MORN Repeats as Protein Binding Modules.
Jian-Chao Li, Haiyang Liu, M. H. Raval, J. Wan +3 more
2019Structure23 citations Open access
Semantic Scholar
Invertebrate and Vertebrate Class III Myosins Interact with MORN Repeat-Containing Adaptor Proteins
K. Mecklenburg, Stephanie A. Freed, M. H. Raval, Omar A. Quintero +2 more
2015PLoS ONE23 citations Open access
Semantic Scholar
Cardiomyopathy Mutations Impact the Actin-Activated Power Stroke of Human Cardiac Myosin.
Wanjian Tang, J. Ge, William C. T. Unrath, Rohini Desetty +1 more
2021Biophysical Journal22 citations Open access
Semantic Scholar
Modulating Beta-Cardiac Myosin Function at the Molecular and Tissue Levels
Wanjian Tang, Cheavar A. Blair, Shane D. Walton, A. Málnási-Csizmadia +2 more
2017Frontiers in Physiology21 citations Open access
Semantic Scholar
Impact of the Motor and Tail Domains of Class III Myosins on Regulating the Formation and Elongation of Actin Protrusions*
M. H. Raval, Omar A. Quintero, Meredith L. Weck, William C. T. Unrath +5 more
2016Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Dilated cardiomyopathy mutation in the converter domain of human cardiac myosin alters motor activity and response to omecamtiv mecarbil
Wanjian Tang, William C. T. Unrath, Rohini Desetty, C. Yengo
2019Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Magnesium impacts myosin V motor activity by altering key conformational changes in the mechanochemical cycle
Darshan V. Trivedi, Joseph M. Muretta, Anja M. Swenson, David D. Thomas +1 more
2013Biochemistry20 citations Open access
Semantic Scholar
Converter domain mutations in myosin alter structural kinetics and motor function
Laura K. Gunther, John A. Rohde, Wanjian Tang, Shane D. Walton +5 more
2018Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Functional Role of Class III Myosins in Hair Cells
Joseph A. Cirilo, Laura K. Gunther, C. Yengo
2021Frontiers in Cell and Developmental Biology15 citations Open access
Semantic Scholar
Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation
M. Doran, M. Rynkiewicz, Elumalai Pavadai, Skylar M. L. Bodt +5 more
2022The Journal of General Physiology13 citations Open access
Semantic Scholar
Tail length and E525K dilated cardiomyopathy mutant alter human β-cardiac myosin super-relaxed state
Sebastian Duno-Miranda, Shane R. Nelson, D. Rasicci, Skylar M. L. Bodt +5 more
2023bioRxiv11 citations Open access
Semantic Scholar
Closing the Therapeutic Loop
K. Campbell, C. Yengo, L. Lee, J. Kotter +3 more
2019Archives of Biochemistry and Biophysics11 citations Open access
Semantic Scholar
A mutation in switch I alters the load-dependent kinetics of myosin Va
Christopher P. Marang, Brent D. Scott, J. Chambers, Laura K. Gunther +2 more
2023Nature Communications8 citations Open access
Semantic Scholar
Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction
Zabed Mahmud, S. Tikunova, N. Belevych, C. Wagg +9 more
2022Frontiers in Physiology8 citations Open access
Semantic Scholar
Dilated cardiomyopathy mutation in beta-cardiac myosin enhances actin activation of the power stroke and phosphate release
Skylar M. L. Bodt, Jing-Hua Ge, Wen Ma, D. Rasicci +3 more
2024PNAS Nexus7 citations Open access
Semantic Scholar
Impact of regulatory light chain mutation K104E on the ATPase and motor properties of cardiac myosin
D. Rasicci, Orville Kirkland, F. Moonschi, N. Wood +5 more
2021The Journal of General Physiology7 citations Open access
Semantic Scholar
The dynamics of actin protrusions can be controlled by tip-localized myosin motors
Joseph A. Cirilo, Xiayi Liao, B. Perrin, C. Yengo
2023Journal of Biological Chemistry6 citations Open access
Semantic Scholar
Nanosurfer assay dissects β-cardiac myosin and cardiac myosin-binding protein C interactions
Anja M. Touma, Wanjian Tang, D. Rasicci, Duha Vang +5 more
2022Biophysical Journal6 citations Open access
Semantic Scholar
Deafness mutation in the MYO3A motor domain impairs actin protrusion elongation mechanism
Laura K. Gunther, Joseph A. Cirilo, Rohini Desetty, C. Yengo
2021Molecular Biology of the Cell4 citations Open access
Semantic Scholar
FRET and optical trapping reveal mechanisms of actin activation of the power stroke and phosphate release in myosin V.
Laura K. Gunther, John A. Rohde, Wanjian Tang, Joseph A. Cirilo +5 more
2020Journal of Biological Chemistry4 citations Open access
Semantic Scholar
Corrigendum: Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
Seham Ebrahim, Matthew R. Avenarius, M. Grati, J. Krey +15 more
2017Nature Communications4 citations Open access
Semantic Scholar
Myosin X dimerization and its impact on cellular functions
Omar A. Quintero, C. Yengo
2012Proceedings of the National Academy of Sciences of the United States of America4 citations Open access
Semantic Scholar
BPS2025 - Cardiac myosin 25-hep E525K mutated construct with mavacamten is stabilized by three blocked head subfragment-2 interactions
R. Sharma, Jing-Hua Ge, C. Yengo, R. Craig +1 more
2025Biophysical Journal3 citations Open access
Semantic Scholar
Steroid-Resistant Nephrotic Syndrome–Associated MYO1E Mutations Have Differential Effects on Myosin 1e Localization, Dynamics, and Activity
Pei-Ju Liu, Laura K. Gunther, Michael E. Garone, Chunling Zhang +11 more
2022Journal of the American Society of Nephrology3 citations Open access
Semantic Scholar
Steroid-resistant nephrotic syndrome associated MYO1E mutations have differential effects on myosin 1e localization, dynamics, and activity
Pei-Ju Liu, Laura K. Gunther, Diana Perez, Jing Bi-Karchin +9 more
2021bioRxiv3 citations
Semantic Scholar
Cardiac myosin motor deficits are associated with left ventricular dysfunction in human ischemic heart failure.
D. Rasicci, J. Ge, G. Milburn, N. Wood +5 more
2022American Journal of Physiology. Heart and Circulatory Physiology2 citations Open access
Semantic Scholar
A dynamic Dab2 keeps myosin VI stably on track
Joseph A. Cirilo, C. Yengo
2021Journal of Biological Chemistry2 citations Open access
Semantic Scholar
Omecamtiv Mecarbil Enhances Actin Affinity and Slows Force Production in Human β-Cardiac Myosin
Anja M. Swenson, Cheavar A. Blair, Christopher M. Fetrow, William C. T. Unrath +4 more
20162 citations Open access
Semantic Scholar
“QuickStainer”: a rapid negative staining device for improved preservation of molecular structure
Vu Nguyen, Ruchi Gautam, A. K. Somavarapu, D. Dutta +5 more
2025bioRxiv1 citations Open access
Semantic Scholar
Early-Stage Alcoholic Cardiomyopathy Highlighted by Metabolic Remodeling, Oxidative Stress, and Cardiac Myosin Dysfunction in Male Rats
D. Rasicci, Jing-Hua Ge, Adrien P Chen, Neil B. Wood +12 more
2025International Journal of Molecular Sciences1 citations
Semantic Scholar
Temperature-dependent FRET reveals uncoupling of the super-relaxed state and interacting heads motif
Jing-Hua Ge, Kevin E W Namitz, Skylar M. L. Bodt, Ianna S. Debrunner +3 more
2024Biophysical Journal1 citations
Semantic Scholar
The role of myosin loop-4 in localizing tropomyosin on actin during muscle activation and relaxation.
M. Doran, M. Rynkiewicz, Elumalai Pavadai, Skylar M. L. Bodt +5 more
2023Biophysical Journal1 citations Open access
Semantic Scholar
The structure and function of the human cardiac actomyosin complex
M. Doran, D. Rasicci, Skylar M. L. Bodt, E. Bullitt +3 more
2022Biophysical Journal1 citations Open access
Semantic Scholar
Impact of Regulatory Light Chain Mutation (K104E) on the Atpase and Motor Properties of Human Cardiac Myosin
D. Rasicci, Orville Kirkland, Wanjian Tang, Rohini Desetty +1 more
20201 citations Open access
Semantic Scholar
FRET and Optical Trapping Measurements Reveal Relationship between Phosphate Release and the Power Stroke in Myosin V
E. Debold, Laura K. Gunther, M. Unger, Brent D. Scott +2 more
20201 citations Open access
Semantic Scholar
Myo3A Motor Activity and Tail Domain Interactions Impact Actin Protrusion Elongation
Laura K. Gunther, Shane R. Nelson, Joseph A. Cirilo, D. Warshaw +1 more
20201 citations Open access
Semantic Scholar

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