Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

A. K. Somavarapu · SciRah

Researcher profile · Semantic Scholar

A. K. Somavarapu

Share profile

A. K. Somavarapu — researcher profile on SciRah

h-index: 13
Works: 29
Citations: 569

Most-cited papers

The Dependence of Amyloid-β Dynamics on Protein Force Fields and Water Models.
A. K. Somavarapu, K. P. Kepp
2015ChemPhysChem113 citations
Semantic Scholar
The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization
Azad Farzadfard, Jannik N. Pedersen, G. Meisl, A. K. Somavarapu +7 more
2022Communications Biology63 citations Open access
Semantic Scholar
Mycobacterium tuberculosis Keto-Mycolic Acid and Macrophage Nuclear Receptor TR4 Modulate Foamy Biogenesis in Granulomas: A Case of a Heterologous and Noncanonical Ligand-Receptor Pair
H. K. Dkhar, R. Nanduri, S. Mahajan, Sandeep Dave +7 more
2014Journal of Immunology60 citations
Semantic Scholar
Loss of stability and hydrophobicity of presenilin 1 mutations causing Alzheimer's disease
A. K. Somavarapu, K. P. Kepp
2016Journal of Neurochemistry47 citations Open access
Semantic Scholar
The dynamic mechanism of presenilin-1 function: Sensitive gate dynamics and loop unplugging control protein access.
A. K. Somavarapu, K. P. Kepp
2016Neurobiology of Disease45 citations Open access
Semantic Scholar
Membrane Dynamics of γ-Secretase Provides a Molecular Basis for β-Amyloid Binding and Processing.
A. K. Somavarapu, Kasper Planeta
2017ACS Chemical Neuroscience42 citations Open access
Semantic Scholar
Discovery of multiple interacting partners of gankyrin, a proteasomal chaperone and an oncoprotein—Evidence for a common hot spot site at the interface and its functional relevance
Padma P. Nanaware, Manoj P. Ramteke, A. K. Somavarapu, Prasanna Venkatraman
2014Proteins: Structure, Function, and Bioinformatics33 citations
Semantic Scholar
A computer-simulated mechanism of familial Alzheimer's disease: Mutations enhance thermal dynamics and favor looser substrate-binding to γ-secretase.
B. Dehury, A. K. Somavarapu, K. P. Kepp
2020Journal of Structural Biology22 citations Open access
Semantic Scholar
Molecular Recipe for γ-Secretase Modulation from Computational Analysis of 60 Active Compounds
Ning Tang, A. K. Somavarapu, K. P. Kepp
2018ACS Omega20 citations Open access
Semantic Scholar
Membrane Dynamics of γ-Secretase Provides a Molecular Basis for β-Amyloid Binding and Processing.
A. K. Somavarapu, K. P. Kepp
2017ACS Chemical Neuroscience17 citations Open access
Semantic Scholar
ONRLDB—manually curated database of experimentally validated ligands for orphan nuclear receptors: insights into new drug discovery
R. Nanduri, Isha Bhutani, A. K. Somavarapu, S. Mahajan +2 more
2015Database J. Biol. Databases Curation17 citations Open access
Semantic Scholar
Direct Correlation of Cell Toxicity to Conformational Ensembles of Genetic Aβ Variants.
A. K. Somavarapu, K. P. Kepp
2015ACS Chemical Neuroscience17 citations Open access
Semantic Scholar
The interactome of stabilized α‐synuclein oligomers and neuronal proteins
Femke Diggelen, S. A. Frank, A. K. Somavarapu, C. Scavenius +5 more
2020The FEBS Journal16 citations
Semantic Scholar
Two Receptor Binding Strategy of SARS-CoV-2 Is Mediated by Both the N-Terminal and Receptor-Binding Spike Domain
Michele Monti, E. Milanetti, Myrthe Frans, Mattia Miotto +15 more
2024Journal of Physical Chemistry B13 citations Open access
Semantic Scholar
Identification of a novel ATPase activity in 14‐3‐3 proteins – Evidence from enzyme kinetics, structure guided modeling and mutagenesis studies
Manoj P. Ramteke, P. Shelke, Vidhya Ramamoorthy, A. K. Somavarapu +5 more
2014FEBS Letters12 citations Open access
Semantic Scholar
Structural interrogation of phosphoproteome identified by mass spectrometry reveals allowed and disallowed regions of phosphoconformation
A. K. Somavarapu, S. Balakrishnan, A. Gautam, David S. Palmer +1 more
2014BMC Structural Biology10 citations Open access
Semantic Scholar
The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+ -Aβ Complex.
A. K. Somavarapu, Fei Shen, K. Teilum, Jing-Dong Zhang +8 more
2017Chemistry6 citations Open access
Semantic Scholar
Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions
A. K. Somavarapu, Giulia Kleijwegt, Madhu Nagaraj, P. Alam +2 more
2023Chemical Science5 citations Open access
Semantic Scholar
Cys-labelling kinetics of membrane protein GlpG: a role for specific SDS binding and micelle changes?
D. Otzen, Jannik N. Pedersen, A. K. Somavarapu, Anders Clement +4 more
2021Biophysical Journal5 citations Open access
Semantic Scholar
Cryo-EM Reveals How Cardiomyopathy Therapeutic Drugs Modulate the Myosin Motors of the Heart
A. K. Somavarapu, Jing-Hua Ge, Christopher M. Yengo, R. Craig +1 more
2025bioRxiv4 citations
Semantic Scholar
A rapid automated system for negative staining EM
Vu Nguyen, A. K. Somavarapu, R. Sharma, D. Dutta +2 more
2024Biophysical Journal2 citations
Semantic Scholar
Cryo-EM reveals how cardiomyopathy therapeutic drugs modulate the myosin motors of the heart
A. K. Somavarapu, Jing-Hua Ge, Christopher M. Yengo, R. Craig +1 more
2026Science Advances1 citations Open access
Semantic Scholar
“QuickStainer”: a rapid negative staining device for improved preservation of molecular structure
Vu Nguyen, Ruchi Gautam, A. K. Somavarapu, D. Dutta +5 more
2025bioRxiv1 citations Open access
Semantic Scholar
The dilated cardiomyopathy E525K mutation stabilizes the cardiac myosin interacting-heads motif while activating the isolated motor domain
R. Gautam, A. K. Somavarapu, Kalen Z. Robeson, M. Childers +5 more
2026bioRxiv0 citations Open access
Semantic Scholar
“QuickStainer”: a rapid negative staining device for improved preservation of molecular structure
Vu Nguyen, R. Gautam, A. K. Somavarapu, D. Dutta +5 more
2026Journal of Structural Biology0 citations Open access
Semantic Scholar
BPS2025 - Mavacamten and omecamtiv mecarbil modulate the structure of the interacting-heads motif by inducing distinct subfragment-2 conformations
A. K. Somavarapu, Jing-Hua Ge, C. Yengo, R. Padrón +1 more
2025Biophysical Journal0 citations Open access
Semantic Scholar
BPS2025 - Differential modulation of beta-cardiac myosin conformations by cardiomyopathy-associated mutations in the converter domain
Jing-Hua Ge, Sebastian Duno-Miranda, A. K. Somavarapu, Skylar M. L. Bodt +7 more
2025Biophysical Journal0 citations Open access
Semantic Scholar
Drug repurposing screens identifies compounds that inhibit α-synuclein oligomers’ membrane disruption and block antibody interactions
A. K. Somavarapu, Giulia Kleijwegt, Madhu Nagaraj, P. Alam +2 more
2022bioRxiv0 citations Open access
Semantic Scholar
website for onrldb
R. Nanduri, Isha Bhutani, A. K. Somavarapu, S. Mahajan +2 more
20150 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Craig×8
Invite
R. Craig — researcher profile on SciRah
R. Padrón×8
Invite
R. Padrón — researcher profile on SciRah
K. P. Kepp×7
Invite
K. P. Kepp — researcher profile on SciRah
Jing-Hua Ge×6
Invite
Jing-Hua Ge — researcher profile on SciRah

×5

Invite

D. Otzen — researcher profile on SciRah

Christopher M. Yengo×4

Invite

Christopher M. Yengo — researcher profile on SciRah

Invite

P. Alam — researcher profile on SciRah

Invite

R. Nanduri — researcher profile on SciRah

Invite

S. Mahajan — researcher profile on SciRah

Invite

R. Parkesh — researcher profile on SciRah

Invite

Pawan Gupta — researcher profile on SciRah

Prasanna Venkatraman×3

Invite

Prasanna Venkatraman — researcher profile on SciRah