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M. Lievens · SciRah

Researcher profile · Semantic Scholar

M. Lievens

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M. Lievens — researcher profile on SciRah

h-index: 42
Works: 91
Citations: 7,495

Most-cited papers

A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants
S. Agnandji, B. Lell, J. Fernandes, B. P. Abossolo +125 more
2012New England Journal of Medicine753 citations Open access
Semantic Scholar
First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children.
S. Agnandji, B. Lell, S. Soulanoudjingar, J. Fernandes +136 more
2011New England Journal of Medicine555 citations Open access
Semantic Scholar
Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection.
K. Kester, J. Cummings, O. Ofori-Anyinam, Christian F. Ockenhouse +16 more
2009Journal of Infectious Diseases528 citations Open access
Semantic Scholar
Efficacy of RTS,S/AS01E Vaccine against Malaria in Children 5 to 17 Months of Age
P. Bejon, J. Lusingu, A. Olotu, Amanda Leach +25 more
2008New England Journal of Medicine431 citations Open access
Semantic Scholar
Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial.
P. Alonso, J. Sacarlal, J. J. Aponte, A. Leach +17 more
2005The Lancet407 citations
Semantic Scholar
Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children
A. Olotu, G. Fegan, J. Wambua, George M. Nyangweso +6 more
2016New England Journal of Medicine389 citations Open access
Semantic Scholar
Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine
D. Neafsey, M. Juraska, T. Bedford, D. Benkeser +59 more
2015New England Journal of Medicine386 citations Open access
Semantic Scholar
Four-Year Efficacy of RTS,S/AS01E and Its Interaction with Malaria Exposure
A. Olotu, G. Fegan, J. Wambua, George M. Nyangweso +8 more
2013New England Journal of Medicine275 citations Open access
Semantic Scholar
Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial.
J. Aponte, P. Aide, Montse Renom, I. Mandomando +18 more
2007The Lancet270 citations
Semantic Scholar
Safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants.
S. Abdulla, Rolf Oberholzer, Omar A. Juma, S. Kubhoja +20 more
2008New England Journal of Medicine238 citations Open access
Semantic Scholar
Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5–17 months in Kenya and Tanzania: a randomised controlled trial
A. Olotu, J. Lusingu, A. Leach, M. Lievens +26 more
2011Lancet. Infectious Diseases (Print)214 citations Open access
Semantic Scholar
Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study.
J. Regules, Susan B. Cicatelli, Jason Bennett, Kristopher M. Paolino +32 more
2016Journal of Infectious Diseases212 citations
Semantic Scholar
Immunogenicity and safety of an adjuvanted hepatitis B vaccine in pre-hemodialysis and hemodialysis patients.
Norella Kong Chiew Tong, J. Beran, S. A. Kee, J. Miguel +10 more
2005Kidney International210 citations Open access
Semantic Scholar
Evaluation of RTS,S/AS02A and RTS,S/AS01B in Adults in a High Malaria Transmission Area
M. Polhemus, Shon A. Remich, B. Ogutu, J. Waitumbi +16 more
2009PLoS ONE144 citations Open access
Semantic Scholar
Long-term safety and efficacy of the RTS,S/AS02A malaria vaccine in Mozambican children.
J. Sacarlal, P. Aide, J. J. Aponte, Montse Renom +18 more
2009Journal of Infectious Diseases139 citations
Semantic Scholar
Safety and efficacy of the RTS,S/AS01E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial.
Kwaku Poku Asante, S. Abdulla, S. Agnandji, J. Lyimo +38 more
2011Lancet. Infectious Diseases (Print)128 citations
Semantic Scholar
Circumsporozoite-Specific T Cell Responses in Children Vaccinated with RTS,S/AS01E and Protection against P falciparum Clinical Malaria
A. Olotu, P. Moris, J. Mwacharo, J. Vekemans +11 more
2011PLoS ONE104 citations Open access
Semantic Scholar
Insights into Long-Lasting Protection Induced by RTS,S/AS02A Malaria Vaccine: Further Results from a Phase IIb Trial in Mozambican Children
C. Guinovart, J. Aponte, J. Sacarlal, P. Aide +9 more
2009PLoS ONE99 citations Open access
Semantic Scholar
Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP
T. Rampling, K. Ewer, Georgina S. Bowyer, C. Bliss +27 more
2016Journal of Infectious Diseases98 citations Open access
Semantic Scholar
Randomized Controlled Trial of RTS,S/AS02D and RTS,S/AS01E Malaria Candidate Vaccines Given According to Different Schedules in Ghanaian Children
S. Owusu-Agyei, D. Ansong, Kwaku Poku Asante, Sandra Kwarteng Owusu +28 more
2009PLoS ONE88 citations Open access
Semantic Scholar
A Randomized Trial Assessing the Safety and Immunogenicity of AS01 and AS02 Adjuvanted RTS,S Malaria Vaccine Candidates in Children in Gabon
B. Lell, S. Agnandji, Isabelle von Glasenapp, Sonja Haertle +12 more
2009PLoS ONE86 citations Open access
Semantic Scholar
Ad35.CS.01 - RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults
C. F. Ockenhouse, J. Regules, Donna M. Tosh, J. Cowden +30 more
2015PLoS ONE78 citations Open access
Semantic Scholar
Design of a phase III multicenter trial to evaluate the efficacy of the RTS,S/AS01 malaria vaccine in children across diverse transmission settings in Africa
A. Leach, J. Vekemans, M. Lievens, O. Ofori-Anyinam +8 more
2011Malaria Journal78 citations Open access
Semantic Scholar
RTS,S/AS02A Malaria Vaccine Does Not Induce Parasite CSP T Cell Epitope Selection and Reduces Multiplicity of Infection
S. Enosse, C. Dobaño, Diana Quelhas, J. Aponte +12 more
2006PLoS Clinical Trials76 citations Open access
Semantic Scholar
Effect of the Pre-erythrocytic Candidate Malaria Vaccine RTS,S/AS01E on Blood Stage Immunity in Young Children
P. Bejon, J. Cook, E. Bergmann-Leitner, A. Olotu +17 more
2011Journal of Infectious Diseases72 citations Open access
Semantic Scholar
Evaluation of the safety and immunogenicity of the RTS,S/AS01E malaria candidate vaccine when integrated in the expanded program of immunization.
S. Agnandji, Kwaku Poku Asante, J. Lyimo, J. Vekemans +38 more
2010Journal of Infectious Diseases68 citations
Semantic Scholar
T Cell Responses to the RTS,S/AS01E and RTS,S/AS02D Malaria Candidate Vaccines Administered According to Different Schedules to Ghanaian Children
D. Ansong, Kwaku Poku Asante, J. Vekemans, S. K. Owusu +25 more
2011PLoS ONE67 citations Open access
Semantic Scholar
Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa
Yolanda Guerra Mendoza, E. Garric, A. Leach, M. Lievens +37 more
2019Human Vaccines & Immunotherapeutics64 citations Open access
Semantic Scholar
Hepatitis A vaccine: Indirect evidence of immune memory 12 years after the primary course
K. van Herck, P. van Damme, M. Lievens, M. Stoffel
2004Journal of Medical Virology64 citations
Semantic Scholar
Impact of RTS,S/AS02A and RTS,S/AS01B on Genotypes of P. falciparum in Adults Participating in a Malaria Vaccine Clinical Trial
J. Waitumbi, Samuel B. Anyona, Carol W. Hunja, Carolyne M. Kifude +9 more
2009PLoS ONE59 citations Open access
Semantic Scholar
Efficacy of RTS,S/AS01E malaria vaccine administered according to different full, fractional, and delayed third or early fourth dose regimens in children aged 5–17 months in Ghana and Kenya: an open-label, phase 2b, randomised controlled trial
Aaron M. Samuels, D. Ansong, S. Kariuki, S. Adjei +22 more
2022Lancet. Infectious Diseases (Print)51 citations Open access
Semantic Scholar
Evaluation of the immune response to RTS,S/AS01 and RTS,S/AS02 adjuvanted vaccines
G. Leroux-Roels, I. Leroux-Roels, F. Clement, O. Ofori-Anyinam +5 more
2014Human Vaccines & Immunotherapeutics51 citations Open access
Semantic Scholar
Long-term incidence of severe malaria following RTS,S/AS01 vaccination in children and infants in Africa: an open-label 3-year extension study of a phase 3 randomised controlled trial.
H. Tinto, W. Otieno, S. Gesase, H. Sorgho +14 more
2019Lancet. Infectious Diseases (Print)50 citations
Semantic Scholar
Safety, Immunogenicity and Duration of Protection of the RTS,S/AS02D Malaria Vaccine: One Year Follow-Up of a Randomized Controlled Phase I/IIb Trial
P. Aide, J. J. Aponte, Montse Renom, T. Nhampossa +12 more
2010PLoS ONE49 citations Open access
Semantic Scholar
Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02D malaria vaccine in infants living in a malaria-endemic region
S. Abdulla, N. Salim, F. Machera, Richard Kamata +17 more
2013Malaria Journal48 citations Open access
Semantic Scholar
Safety and efficacy of novel malaria vaccine regimens of RTS,S/AS01B alone, or with concomitant ChAd63-MVA-vectored vaccines expressing ME-TRAP
T. Rampling, K. Ewer, Georgina S. Bowyer, N. Edwards +31 more
2018npj Vaccines47 citations Open access
Semantic Scholar
Induction of Plasmodium falciparum-Specific CD4+ T Cells and Memory B Cells in Gabonese Children Vaccinated with RTS,S/AS01E and RTS,S/AS02D
S. Agnandji, Rolf Fendel, M. Mestré, M. Janssens +19 more
2011PLoS ONE47 citations Open access
Semantic Scholar
RTS,S malaria vaccine efficacy and immunogenicity during Plasmodium falciparum challenge is associated with HLA genotype
C. Nielsen, J. Vekemans, M. Lievens, K. Kester +2 more
2018Vaccine46 citations Open access
Semantic Scholar
Safety of the RTS,S/AS02A malaria vaccine in Mozambican children during a Phase IIb trial.
J. Sacarlal, J. J. Aponte, P. Aide, I. Mandomando +15 more
2008Vaccine44 citations
Semantic Scholar
Four year immunogenicity of the RTS,S/AS02(A) malaria vaccine in Mozambican children during a phase IIb trial.
P. Aide, C. Dobaño, J. Sacarlal, J. J. Aponte +16 more
2011Vaccine43 citations
Semantic Scholar
The effect of immunization schedule with the malaria vaccine candidate RTS,S/AS01E on protective efficacy and anti-circumsporozoite protein antibody avidity in African infants
A. Ajua, B. Lell, S. Agnandji, Kwaku Poku Asante +13 more
2015Malaria Journal42 citations Open access
Semantic Scholar
Serological Evidence of Discrete Spatial Clusters of Plasmodium falciparum Parasites
P. Bejon, L. Turner, T. Lavstsen, G. Cham +10 more
2011PLoS ONE42 citations Open access
Semantic Scholar
Five-year safety and immunogenicity of GlaxoSmithKline’s candidate malaria vaccine RTS,S/AS02 following administration to semi-immune adult men living in a malaria-endemic region of The Gambia
K. Bojang, P. Milligan, M. Pinder, T. Doherty +7 more
2009Human Vaccines42 citations Open access
Semantic Scholar
Immunogenicity of Twinrix™ in older adults: a critical analysis
M. Stoffel, M. Lievens, I. Dieussaert, Isabelle Martin +1 more
2003Expert Review of Vaccines38 citations
Semantic Scholar
Immunogenicity and Safety Following 1 Dose of AS01E-Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older Adults: A Phase 3 Trial
Tino F. Schwarz, Shinn-Jang Hwang, Pedro Ylisastigui, Chiu-Shong Liu +16 more
2023Journal of Infectious Diseases36 citations Open access
Semantic Scholar
A Phase IIa Controlled Human Malaria Infection and Immunogenicity Study of RTS,S/AS01E and RTS,S/AS01B Delayed Fractional Dose Regimens in Malaria-Naive Adults
James E. Moon, C. Ockenhouse, J. Regules, J. Vekemans +37 more
2020Journal of Infectious Diseases36 citations Open access
Semantic Scholar
Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children
J. Lusingu, A. Olotu, A. Leach, M. Lievens +28 more
2010PLoS ONE29 citations Open access
Semantic Scholar
Safety and immunogenicity of RTS,S/AS01 malaria vaccine in infants and children with WHO stage 1 or 2 HIV disease: a randomised, double-blind, controlled trial
L. Otieno, M. Oneko, W. Otieno, J. Abuodha +23 more
2016Lancet. Infectious Diseases (Print)28 citations Open access
Semantic Scholar
Development and Technical and Clinical Validation of a Quantitative Enzyme-Linked Immunosorbent Assay for the Detection of Human Antibodies to Hepatitis B Surface Antigen in Recipients of Recombinant Hepatitis B Virus Vaccine
P. Cambron, J. Jacquet, B. Hoet, M. Lievens
2009Clinical and Vaccine Immunology27 citations Open access
Semantic Scholar
Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS , S / AS 01 malaria vaccine in African children
M. Lievens, J. Aponte, J. Williamson, B. Mmbando +3 more
201126 citations
Semantic Scholar

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