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J. Wambua · SciRah

Researcher profile · Semantic Scholar

J. Wambua

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J. Wambua — researcher profile on SciRah

h-index: 22
Works: 47
Citations: 2,044

Most-cited papers

Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children
A. Olotu, G. Fegan, J. Wambua, George M. Nyangweso +6 more
2016New England Journal of Medicine390 citations Open access
Semantic Scholar
Four-Year Efficacy of RTS,S/AS01E and Its Interaction with Malaria Exposure
A. Olotu, G. Fegan, J. Wambua, George M. Nyangweso +8 more
2013New England Journal of Medicine275 citations Open access
Semantic Scholar
Stable and Unstable Malaria Hotspots in Longitudinal Cohort Studies in Kenya
P. Bejon, T. Williams, Anne Liljander, A. Noor +7 more
2010PLoS Medicine270 citations Open access
Semantic Scholar
A LAIR-1 insertion generates broadly reactive antibodies against malaria variant antigens
Joshua Tan, Kathrin Pieper, L. Piccoli, A. Abdi +17 more
2015Nature155 citations Open access
Semantic Scholar
Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions.
R. Payne, S. Silk, S. Elias, K. Miura +38 more
2017JCI Insight121 citations Open access
Semantic Scholar
Wind direction and proximity to larval sites determines malaria risk in Kilifi District in Kenya
J. Midega, Dave L. Smith, A. Olotu, J. Mwangangi +7 more
2012Nature Communications99 citations Open access
Semantic Scholar
The Ratio of Monocytes to Lymphocytes in Peripheral Blood Correlates with Increased Susceptibility to Clinical Malaria in Kenyan Children
G. Warimwe, L. Murungi, Gathoni Kamuyu, George M. Nyangweso +7 more
2013PLoS ONE73 citations Open access
Semantic Scholar
Repeated clinical malaria episodes are associated with modification of the immune system in children
Y. Bediako, R. Adams, A. Reid, J. Valletta +20 more
2019BMC Medicine68 citations Open access
Semantic Scholar
Defining Clinical Malaria: The Specificity and Incidence of Endpoints from Active and Passive Surveillance of Children in Rural Kenya
A. Olotu, G. Fegan, T. Williams, Philip G. Sasi +6 more
2010PLoS ONE51 citations Open access
Semantic Scholar
Estimating Individual Exposure to Malaria Using Local Prevalence of Malaria Infection in the Field
A. Olotu, G. Fegan, J. Wambua, George M. Nyangweso +4 more
2012PLoS ONE44 citations Open access
Semantic Scholar
Detecting Malaria Hotspots: A Comparison of Rapid Diagnostic Test, Microscopy, and Polymerase Chain Reaction
Polycarp Mogeni, T. Williams, Irene Omedo, D. Kimani +9 more
2017Journal of Infectious Diseases43 citations Open access
Semantic Scholar
Plasmodium falciparum var Gene Expression Homogeneity as a Marker of the Host-Parasite Relationship under Different Levels of Naturally Acquired Immunity to Malaria
G. Warimwe, M. Recker, Esther W. Kiragu, C. Buckee +4 more
2013PLoS ONE32 citations Open access
Semantic Scholar
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria
D. Odera, J. Tuju, K. Mwai, I. Nkumama +66 more
2023Science Translational Medicine31 citations
Semantic Scholar
Transmission and Age Impact the Risk of Developing Febrile Malaria in Children with Asymptomatic Plasmodium falciparum Parasitemia
K. Wamae, J. Wambua, George M. Nyangweso, G. Mwambingu +4 more
2018Journal of Infectious Diseases31 citations Open access
Semantic Scholar
Controlled Human Malaria Infection in Semi-Immune Kenyan Adults (CHMI-SIKA): a study protocol to investigate in vivo malaria parasite growth in the context of Plasmodium falciparum
P. Njuguna, M. Hamaluba, A. Abdi, Y. Abebe +62 more
201830 citations
Semantic Scholar
Identifying children with excess malaria episodes after adjusting for variation in exposure: identification from a longitudinal study using statistical count models
F. Ndungu, K. Marsh, G. Fegan, J. Wambua +8 more
2015BMC Medicine27 citations Open access
Semantic Scholar
Arterolane–piperaquine–mefloquine versus arterolane–piperaquine and artemether–lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a single-centre, open-label, randomised, non-inferiority trial
M. Hamaluba, R. W. van der Pluijm, J. Weya, P. Njuguna +23 more
2021Lancet. Infectious Diseases (Print)26 citations Open access
Semantic Scholar
The effect of declining exposure on T cell-mediated immunity to Plasmodium falciparum – an epidemiological “natural experiment”
Y. Bediako, J. Ngoi, George M. Nyangweso, J. Wambua +5 more
2016BMC Medicine26 citations Open access
Semantic Scholar
Controlled human malaria infection (CHMI) outcomes in Kenyan adults is associated with prior history of malaria exposure and anti-schizont antibody response
M. Kapulu, D. Kimani, P. Njuguna, M. Hamaluba +38 more
2022BMC Infectious Diseases25 citations Open access
Semantic Scholar
Malaria exposure drives both cognate and bystander human B cells to adopt an atypical phenotype
R. Aye, H. Sutton, E. Nduati, O. Kai +7 more
2019European Journal of Immunology25 citations Open access
Semantic Scholar
Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria
F. Musasia, I. Nkumama, R. Frank, Victor Kipkemboi +45 more
2022Nature Communications23 citations Open access
Semantic Scholar
Longitudinal Analysis of Infant Stool Bacteria Communities Before and After Acute Febrile Malaria and Artemether-Lumefantrine Treatment
R. Mandal, Rosie J. Crane, J. Berkley, W. Gumbi +4 more
2018Journal of Infectious Diseases23 citations Open access
Semantic Scholar
The Design and Evaluation of a Mobile System for Rapid Diagnostic Test Interpretation
Chunjong Park, Hung Ngo, L. Lavitt, Vincent Karuri +15 more
2021Proceedings of the ACM on Interactive Mobile Wearable and Ubiquitous Technologies22 citations Open access
Semantic Scholar
Seven-year kinetics of RTS, S/AS01-induced anti-CSP antibodies in young Kenyan children
R. Mugo, K. Mwai, J. Mwacharo, Faiz Shee +5 more
2021Malaria Journal18 citations Open access
Semantic Scholar
Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort
M. Muthui, Polycarp Mogeni, K. Mwai, C. Nyundo +8 more
2019Wellcome Open Research16 citations Open access
Semantic Scholar
Understanding the benefits and burdens associated with a malaria human infection study in Kenya: experiences of study volunteers and other stakeholders
P. Chi, E. Owino, I. Jao, Fredrick O. Olewe +57 more
2021Trials15 citations Open access
Semantic Scholar
Cessation of exclusive breastfeeding and seasonality, but not small intestinal bacterial overgrowth, are associated with environmental enteric dysfunction: A birth cohort study amongst infants in rural Kenya
Rosie J. Crane, E. Parker, Simon Fleming, A. Gwela +8 more
2022EClinicalMedicine11 citations Open access
Semantic Scholar
Bayesian evaluation of the performance of three diagnostic tests for Plasmodium falciparum infection in a low-transmission setting in Kilifi County, Kenya
M. Mweu, J. Wambua, Fixtan Njuga, Philip Bejon +1 more
2019Wellcome Open Research11 citations Open access
Semantic Scholar
Low frequency of Plasmodium falciparum hrp2/3 deletions from symptomatic infections at a primary healthcare facility in Kilifi, Kenya
Dorcas Okanda, L. Ndwiga, Victor Osoti, Nicole Achieng +6 more
2023Frontiers in Epidemiology10 citations Open access
Semantic Scholar
Characterization of Naturally Acquired Immunity to a Panel of Antigens Expressed in Mature P. falciparum Gametocytes
M. Muthui, Eizo Takashima, B. R. Omondi, Christine Kinya +11 more
2021Frontiers in Cellular and Infection Microbiology10 citations Open access
Semantic Scholar
A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01 E on blood stage immunity in young Kenyan children
F. Ndungu, J. Mwacharo, J. Wambua, P. Njuguna +3 more
2019Wellcome Open Research10 citations Open access
Semantic Scholar
Undertaking Community Engagement for a Controlled Human Malaria Infection Study in Kenya: Approaches and Lessons Learnt
N. Mumba, P. Njuguna, P. Chi, V. Marsh +12 more
2022Frontiers in Public Health9 citations Open access
Semantic Scholar
Multiple clinical episodes of Plasmodium falciparum malaria in a low transmission intensity setting: exposure versus immunity
Josea Rono, A. Färnert, L. Murungi, J. Ojal +8 more
2015BMC Medicine9 citations Open access
Semantic Scholar
Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected
K. Kimenyi, M. Akinyi, Kioko Mwikali, Tegan Gilmore +10 more
2024BMC Infectious Diseases4 citations Open access
Semantic Scholar
R21 malaria vaccine is protective against intradermal but not intravenous Plasmodium falciparum sporozoites in a randomized controlled human malaria infection study in Kenyan adults
M. Kapulu, F. Orenge, D. Kimani, E. Kibwana +35 more
2024medRxiv3 citations Open access
Semantic Scholar
Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial
K. Wamae, L. Ndwiga, Oksana Kharabora, K. Kimenyi +14 more
2022Wellcome Open Research3 citations Open access
Semantic Scholar
Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort [version 2; peer review: 2 approved]
M. Muthui, Polycarp Mogeni, K. Mwai, C. Nyundo +8 more
20213 citations
Semantic Scholar
Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial [version 2; peer review: 2 approved, 2 approved with reservations]
K. Wamae, L. Ndwiga, Oksana Kharabora, K. Kimenyi +14 more
20232 citations
Semantic Scholar
Evaluation of near infrared spectroscopy for sporozoite detection in mosquitoes infected with wild-strain parasites from asymptomatic gametocyte carriers in Kilifi Kenya
M. Maia, Martin G. Wagah, Jonathan Karisa, Robert Mwakesi +7 more
2020bioRxiv2 citations Open access
Semantic Scholar
Correction: Defining Clinical Malaria: The Specificity and Incidence of Endpoints from Active and Passive Surveillance of Children in Rural Kenya
A. Olotu, G. Fegan, T. Williams, Philip G. Sasi +6 more
2011PLoS ONE2 citations Open access
Semantic Scholar
Correction: Stable and Unstable Malaria Hotspots in Longitudinal Cohort Studies in Kenya
P. Bejon, T. Williams, Anne Liljander, A. Noor +7 more
2011PLoS Medicine2 citations Open access
Semantic Scholar
WIND DIRECTION AND PROXIMITY TO LARVAL SITES DETERMINES MALARIA RISK IN KILIFI, KENYA
J. Midega, David L. Smith, A. Olotu, J. Mwangangi +6 more
20131 citations
Semantic Scholar
Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial [version 2; peer review: 2 approved with reservations]
K. Wamae, L. Ndwiga, Oksana Kharabora, K. Kimenyi +14 more
20220 citations
Semantic Scholar
Replication data for: Characterization of naturally acquired immunity to a panel of antigens expressed in mature P. falciparum gametocytes
M. Muthui, Eizo Takashima, B. R. Omondi, Christine Kinya +11 more
20210 citations
Semantic Scholar
INVESTIGATING IMMUNE SIGNATURES IN MALARIA-EXPOSED CHILDREN
Y. Bediako, R. Adams, A. Reid, J. Valletta +19 more
20180 citations
Semantic Scholar
' s response to reviews Title : Identifying Children with Excess Malaria Episodes after adjusting for Variation in Exposure : Identification from a Longitudinal Study Using Statistical Count Models
Francis M. Ndungu, Kevin Marsh, G. Fegan, J. Wambua +8 more
20150 citations
Semantic Scholar
Targeted Amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial [version 1; peer review: 2 approved with reservations]
K. Wamae, L. Ndwiga, Oksana Kharabora, K. Kimenyi +16 more
0 citations
Semantic Scholar

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