Researcher profile · Semantic Scholar

Bhanu Chandra Mulukutla

h-index: 15
Works: 25
Citations: 1,308

Most-cited papers

On metabolic shift to lactate consumption in fed-batch culture of mammalian cells.
Bhanu Chandra Mulukutla, M. Gramer, Wei-Shou Hu
2012Metabolic Engineering179 citations
Semantic Scholar
Glucose metabolism in mammalian cell culture: new insights for tweaking vintage pathways.
Bhanu Chandra Mulukutla, S. Khan, A. Lange, Wei-Shou Hu
2010Trends in Biotechnology142 citations
Semantic Scholar
Regulation of Glucose Metabolism - A Perspective From Cell Bioprocessing.
Bhanu Chandra Mulukutla, Andrew Yongky, T. Le, Douglas G. Mashek +1 more
2016Trends in Biotechnology141 citations
Semantic Scholar
Systems Analysis of N-Glycan Processing in Mammalian Cells
Patrick Hossler, Bhanu Chandra Mulukutla, Wei-Shou Hu
2007PLoS ONE136 citations Open access
Semantic Scholar
Identification and control of novel growth inhibitors in fed‐batch cultures of Chinese hamster ovary cells
Bhanu Chandra Mulukutla, J. Kale, Taylor Kalomeris, M. Jacobs +1 more
2017Biotechnology and Bioengineering121 citations
Semantic Scholar
Bistability in Glycolysis Pathway as a Physiological Switch in Energy Metabolism
Bhanu Chandra Mulukutla, Andrew Yongky, Prodromos Daoutidis, Wei-Shou Hu
2014PLoS ONE78 citations Open access
Semantic Scholar
Forecasting and control of lactate bifurcation in Chinese hamster ovary cell culture processes
J. Schmitt, Brandon J. Downey, Justin A. Beller, Brian Russell +5 more
2019Biotechnology and Bioengineering76 citations Open access
Semantic Scholar
Multiplicity of Steady States in Glycolysis and Shift of Metabolic State in Cultured Mammalian Cells
Bhanu Chandra Mulukutla, Andrew Yongky, Simon Grimm, Prodromos Daoutidis +1 more
2015PLoS ONE76 citations Open access
Semantic Scholar
Metabolic engineering of Chinese hamster ovary cells towards reduced biosynthesis and accumulation of novel growth inhibitors in fed-batch cultures.
Bhanu Chandra Mulukutla, Jeffrey Mitchell, P. Geoffroy, C. Harrington +6 more
2019Metabolic Engineering68 citations
Semantic Scholar
Small-molecule control of antibody N-glycosylation in engineered mammalian cells
Michelle M. Chang, L. Gaidukov, Giyoung Jung, Wen Allen Tseng +16 more
2019Nature Chemical Biology67 citations Open access
Semantic Scholar
Dissecting N-Glycosylation Dynamics in Chinese Hamster Ovary Cells Fed-batch Cultures using Time Course Omics Analyses
M. Sumit, Sepideh Dolatshahi, An-Hsiang Adam Chu, Kaffa Cote +7 more
2019iScience63 citations Open access
Semantic Scholar
Developing genomic platforms for Chinese hamster ovary cells.
Anne Kantardjieff, P. M. Nissom, Hui-Chu-Ah Song, F. Yusufi +4 more
2009Biotechnology Advances58 citations
Semantic Scholar
Regulation of Metabolic Homeostasis in Cell Culture Bioprocesses.
Conor M. O'Brien, Bhanu Chandra Mulukutla, Douglas G. Mashek, Wei-Shou Hu
2020Trends in Biotechnology36 citations
Semantic Scholar
Reaching the depth of the Chinese hamster ovary cell transcriptome.
Nitya M. Jacob, Anne Kantardjieff, F. Yusufi, E. Retzel +4 more
2010Biotechnology and Bioengineering35 citations
Semantic Scholar
Mechanism for multiplicity of steady states with distinct cell concentration in continuous culture of mammalian cells
Andrew Yongky, Jongchan Lee, T. Le, Bhanu Chandra Mulukutla +2 more
2015Biotechnology and Bioengineering17 citations
Semantic Scholar
Production of butyrate and branched‐chain amino acid catabolic byproducts by CHO cells in fed‐batch culture enhances their specific productivity
C. Harrington, M. Jacobs, Quentin Bethune, Taylor Kalomeris +2 more
2021Biotechnology and Bioengineering12 citations Open access
Semantic Scholar
Metabolic Engineering of CHO Cells Towards Cysteine Prototrophy and Systems Analysis of The Ensuing Phenotype.
L. Greenfield, Mariah Brantley, P. Geoffroy, Jeffrey Mitchell +3 more
2024Metabolic Engineering7 citations
Semantic Scholar
A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction
Ke-Qi Wang, Keilung Choy, Eli Reiser, Jin-Xiang Pei +9 more
2026Biotechnology and Bioengineering2 citations Open access
Semantic Scholar
Uncovering Growth‐Inhibitory Metabolic Byproducts in HEK293 Fed‐Batch Cultures and Strategies for Their Control
C. Harrington, Bhanu Chandra Mulukutla
2025Biotechnology Journal2 citations
Semantic Scholar
Lactate Control Enhances Growth Advantage in Fed-batch Cultures of Metabolically Engineered CHO Cells with Reduced Novel Growth-inhibitory Compound Formation
Quentin Bethune, C. Harrington, Bhanu Chandra Mulukutla
20211 citations Open access
Semantic Scholar
BioOps: Enabling MLOps for scalable and flexible model-centric process control in biopharmaceutical development.
Shu Yang, Edwin M. Shen, Piyush Agarwal, Amer Al Lozi +18 more
2026Biotechnology progress (Print)0 citations Open access
Semantic Scholar
Corrigendum
J. Schmitt, Brandon J. Downey, Justin A. Beller, Brian Russell +6 more
2019Biotechnology and Bioengineering0 citations Open access
Semantic Scholar
Dissecting the Dynamics of N-Linked Glycosylation in Fed-Batch Cultures of Chinese Hamster Ovary Cells Through Time Course Omics Analyses
M. Sumit, Sepideh Dolatshahi, An-Hsiang Adam Chu, Kaffa Cote +7 more
20180 citations Open access
Semantic Scholar
TIBTEC 1384 No . of Pages 14 Allosteric Regulation and High Glycolysis Flux
Bhanu Chandra Mulukutla, Andrew Yongky, T. Le, Douglas G. Mashek +1 more
20160 citations
Semantic Scholar
Systems analysis of glucose metabolism of cultured mammalian cells
Bhanu Chandra Mulukutla
20120 citations
Semantic Scholar

Douglas G. Mashek

×3

Taylor Kalomeris×3

G. Hiller×3

Prodromos Daoutidis×3

John J. Scarcelli×3

Richard J. Cornell×3

Jeffrey K. Marshall×3

An-Hsiang Adam Chu×3