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Douglas G. Mashek · SciRah

Researcher profile · Semantic Scholar

Douglas G. Mashek

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Douglas G. Mashek — researcher profile on SciRah

h-index: 45
Works: 138
Citations: 11K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
ATGL promotes autophagy/lipophagy via SIRT1 to control hepatic lipid droplet catabolism
Aishwarya Sathyanarayan, M. Mashek, Douglas G. Mashek
2017Cell Reports342 citations Open access
Semantic Scholar
Breaking fat: the regulation and mechanisms of lipophagy
Ryan J. Schulze, Aishwarya Sathyanarayan, Douglas G. Mashek
2017Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids221 citations Open access
Semantic Scholar
Hepatic lipid droplets: A balancing act between energy storage and metabolic dysfunction in NAFLD
Douglas G. Mashek
2020Molecular Metabolism220 citations Open access
Semantic Scholar
ATGL-Catalyzed Lipolysis Regulates SIRT1 to Control PGC-1α/PPAR-α Signaling
S. Khan, Aishwarya Sathyanarayan, M. Mashek, Kuok Teong Ong +2 more
2015Diabetes167 citations Open access
Semantic Scholar
Hepatic fatty acid trafficking: multiple forks in the road.
Douglas G. Mashek
2013Advances in Nutrition143 citations Open access
Semantic Scholar
Lipid droplet-derived monounsaturated fatty acids traffic via PLIN5 to allosterically activate SIRT1
Charles P. Najt, S. Khan, Timothy D. Heden, B. Witthuhn +11 more
2019Molecules and Cells141 citations Open access
Semantic Scholar
Regulation of Glucose Metabolism - A Perspective From Cell Bioprocessing.
Bhanu Chandra Mulukutla, Andrew Yongky, T. Le, Douglas G. Mashek +1 more
2016Trends in Biotechnology141 citations
Semantic Scholar
Palmitoleate Induces Hepatic Steatosis but Suppresses Liver Inflammatory Response in Mice
Xin Guo, Honggui Li, Hang Xu, Vera Halim +11 more
2012PLoS ONE137 citations Open access
Semantic Scholar
Lipophagy-derived fatty acids undergo extracellular efflux via lysosomal exocytosis
Wenqi Cui, Aishwarya Sathyanarayan, Michael W. Lopresti, M. Aghajan +2 more
2020Autophagy119 citations Open access
Semantic Scholar
Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption
T. A. Bowman, Kayleigh R. O'Keeffe, Theresa D’Aquila, Qing-Wu Yan +6 more
2016Molecular Metabolism96 citations Open access
Semantic Scholar
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity
Timothy D. Heden, Jordan M. Johnson, Patrick J. Ferrara, Hiroaki Eshima +23 more
2019Science Advances85 citations Open access
Semantic Scholar
Integrated Regulation of Hepatic Lipid and Glucose Metabolism by ATGL and FoxO Proteins
Wenwei Zhang, S. Bu, M. Mashek, I. O-Sullivan +6 more
2016Cell Reports79 citations Open access
Semantic Scholar
Organelle interactions compartmentalize hepatic fatty acid trafficking and metabolism
Charles P. Najt, Santosh Adhikari, Timothy D. Heden, Wenqi Cui +12 more
2023Cell Reports77 citations Open access
Semantic Scholar
Acyl-CoA Thioesterase 1 (ACOT1) Regulates PPARα to Couple Fatty Acid Flux With Oxidative Capacity During Fasting
Mallory P. Franklin, Aishwarya Sathyanarayan, Douglas G. Mashek
2017Diabetes72 citations Open access
Semantic Scholar
Lipocalin 2 Regulates Brown Fat Activation via a Nonadrenergic Activation Mechanism*
Yuanyuan Zhang, Hong Guo, Jessica A. Deis, Mara G Mashek +6 more
2014Journal of Biological Chemistry69 citations Open access
Semantic Scholar
Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α
E. Hanse, Douglas G. Mashek, Jennifer R. Becker, Ashley Solmonson +5 more
2012Cell Cycle69 citations Open access
Semantic Scholar
Quantitative analysis of the murine lipid droplet-associated proteome during diet-induced hepatic steatosis[S]
S. Khan, Edith E. Wollaston-Hayden, Todd W. Markowski, LeeAnn Higgins +1 more
2015Journal of Lipid Research65 citations Open access
Semantic Scholar
Targeted Overexpression of Inducible 6-Phosphofructo-2-kinase in Adipose Tissue Increases Fat Deposition but Protects against Diet-induced Insulin Resistance and Inflammatory Responses*
Yuqing Huo, Xin Guo, Honggui Li, Hang Xu +13 more
2012Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation
Kuok Teong Ong, M. Mashek, S. Bu, Douglas G. Mashek
2013The FASEB Journal51 citations Open access
Semantic Scholar
Regulation and role of glycophagy in skeletal muscle energy metabolism
Timothy D. Heden, Lisa S. Chow, Curtis C. Hughey, Douglas G. Mashek
2021Autophagy48 citations Open access
Semantic Scholar
Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism
Kuok Teong Ong, M. Mashek, N. Davidson, Douglas G. Mashek
2014Journal of Lipid Research47 citations Open access
Semantic Scholar
Perilipins at a glance.
Charles P. Najt, Mahima Devarajan, Douglas G. Mashek
2022Journal of Cell Science46 citations Open access
Semantic Scholar
AMP-activated protein kinase α1 protects against diet-induced insulin resistance and obesity. Diabetes 2012;61:3114–3125
Wenwei Zhang, X. Zhang, H. Wang, Xin Guo +15 more
2013Diabetes46 citations Open access
Semantic Scholar
Hepatic PLIN5 signals via SIRT1 to promote autophagy and prevent inflammation during fasting[S]
E. Zhang, Wenqi Cui, Michael W. Lopresti, Mara G Mashek +3 more
2020Journal of Lipid Research45 citations Open access
Semantic Scholar
Unconventional Secretion of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins in a Sirtuin-1–Dependent Manner
Ajeetha Josephrajan, Ann V. Hertzel, Ellie K. Bohm, M. McBurney +4 more
2019Diabetes45 citations Open access
Semantic Scholar
AMP-Activated Protein Kinase α1 Protects Against Diet-Induced Insulin Resistance and Obesity
Weiyu Zhang, Xianling Zhang, Huan Wang, Xin Guo +15 more
2012Diabetes42 citations Open access
Semantic Scholar
Regulation of Metabolic Homeostasis in Cell Culture Bioprocesses.
Conor M. O'Brien, Bhanu Chandra Mulukutla, Douglas G. Mashek, Wei-Shou Hu
2020Trends in Biotechnology36 citations
Semantic Scholar
Muscle Lipid Droplets: Cellular Signaling to Exercise Physiology and Beyond
J. Seibert, Charles P. Najt, Timothy D. Heden, Douglas G. Mashek +1 more
2020Trends in endocrinology and metabolism35 citations Open access
Semantic Scholar
Effect of acute physiological free fatty acid elevation in the context of hyperinsulinemia on fiber type-specific IMCL accumulation.
Lisa S. Chow, Douglas G. Mashek, Qi Wang, S. Shepherd +2 more
2017Journal of applied physiology31 citations Open access
Semantic Scholar
Cyclin D1 represses peroxisome proliferator-activated receptor alpha and inhibits fatty acid oxidation
Sushama Kamarajugadda, Jennifer R. Becker, E. Hanse, Douglas G. Mashek +4 more
2016OncoTarget31 citations Open access
Semantic Scholar
Training status diverges muscle diacylglycerol accumulation during free fatty acid elevation.
Lisa S. Chow, Douglas G. Mashek, E. Austin, L. Eberly +4 more
2014American Journal of Physiology. Endocrinology and Metabolism31 citations Open access
Semantic Scholar
The impact of a self-selected time restricted eating intervention on eating patterns, sleep, and late-night eating in individuals with obesity
Stacey L. Simon, Jennifer M. Blankenship, E. Manoogian, Satchidananda Panda +2 more
2022Frontiers in Nutrition30 citations Open access
Semantic Scholar
Training alters the distribution of perilipin proteins in muscle following acute free fatty acid exposure
S. Shepherd, J. Strauss, Qi Wang, John J. Dubé +3 more
2017Journal of Physiology30 citations Open access
Semantic Scholar
Time-Restricted Eating Improves Quality of Life Measures in Overweight Humans
Ainslee Crose, Alison C. Alvear, Stephanie Singroy, Qi Wang +4 more
2021Nutrients29 citations Open access
Semantic Scholar
Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver[S]
A. Nerstedt, Y. Kurhe, Emmelie Cansby, M. Caputo +11 more
2019Journal of Lipid Research29 citations Open access
Semantic Scholar
TREM2 macrophages mediate the beneficial effects of bariatric surgery against MASH
G. Fredrickson, Kira Florczak, Fanta Barrow, Shamsed Mahmud +15 more
2024Hepatology28 citations Open access
Semantic Scholar
Toll-like receptor 4 signaling is required for induction of gluconeogenic gene expression by palmitate in human hepatic carcinoma cells
L. Mamedova, Kai Yuan, Amber N Laudick, S. Fleming +2 more
2013Journal of Nutritional Biochemistry28 citations Open access
Semantic Scholar
ACOT1 deficiency attenuates high-fat diet–induced fat mass gain by increasing energy expenditure
Timothy D. Heden, Mallory P. Franklin, Christina Dailey, M. Mashek +2 more
2023JCI Insight25 citations Open access
Semantic Scholar
Time‐restricted eating, caloric reduction, and unrestricted eating effects on weight and metabolism: a randomized trial
Niki Oldenburg, Douglas G. Mashek, Lisa Harnack, Qi Wang +20 more
2025Obesity24 citations Open access
Semantic Scholar
Time-Restricted Eating for 12 Weeks Does Not Adversely Alter Bone Turnover in Overweight Adults
Andrea J. Lobene, Satchidananda Panda, Douglas G. Mashek, E. Manoogian +2 more
2021Nutrients24 citations Open access
Semantic Scholar
Mechanisms coupling lipid droplets to MASLD pathophysiology.
M. Reid, Gavin Fredickson, Douglas G. Mashek
2024Hepatology22 citations
Semantic Scholar
Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes
Heng Wu, Jonathan M. Ploeger, Sushama Kamarajugadda, Douglas G. Mashek +5 more
2019Hepatology Communications20 citations Open access
Semantic Scholar
Caloric Restriction Prevents Carcinogen-Initiated Liver Tumorigenesis in Mice
Jonathan M. Ploeger, J. Manivel, Lauren Boatner, Douglas G. Mashek
2017Cancer Prevention Research20 citations Open access
Semantic Scholar
Phosphatase PHLPP2 regulates the cellular response to metabolic stress through AMPK
Yan Yan, K. Krecke, Aditi S. Bapat, Tingyuan Yang +3 more
2021Cell Death and Disease19 citations Open access
Semantic Scholar
Acute free fatty acid elevation eliminates endurance training effect on insulin sensitivity.
Lisa S. Chow, E. Seaquist, L. Eberly, M. Mashek +3 more
2012Journal of Clinical Endocrinology and Metabolism17 citations Open access
Semantic Scholar
Time-Restricted Eating Alters Food Intake Patterns, as Prospectively Documented by a Smartphone Application
Samar Malaeb, T. Harindhanavudhi, Katrina Dietsche, Nicholas Esch +5 more
2020Nutrients16 citations Open access
Semantic Scholar
Hepatic lysosomal acid lipase overexpression worsens hepatic inflammation in mice fed a Western diet
Michael W. Lopresti, Wenqi Cui, Breann E. Abernathy, G. Fredrickson +4 more
2021Journal of Lipid Research15 citations Open access
Semantic Scholar
New lipid‐producing, cold‐tolerant yellow‐green alga isolated from the rocky mountains of colorado
David R. Nelson, Sinafik Mengistu, Paul T Ranum, G. Celio +3 more
2013Biotechnology progress (Print)14 citations
Semantic Scholar
Algal swimming velocities signal fatty acid accumulation
T. Hansen, M. Hondzo, M. Mashek, Douglas G. Mashek +1 more
2013Biotechnology and Bioengineering14 citations
Semantic Scholar

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Lisa S. Chow×10
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Timothy D. Heden×6
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Aishwarya Sathyanarayan×5
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Charles P. Najt×5

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Honggui Li — researcher profile on SciRah

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Yuqing Huo — researcher profile on SciRah

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