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John J. Scarcelli · SciRah

Researcher profile · Semantic Scholar

John J. Scarcelli

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John J. Scarcelli — researcher profile on SciRah

h-index: 15
Works: 29
Citations: 1,039

Most-cited papers

The DEAD-Box RNA Helicase Dbp5 Functions in Translation Termination
T. Gross, A. Siepmann, D. Sturm, M. Windgassen +4 more
2007Science147 citations
Semantic Scholar
Transport of messenger RNA from the nucleus to the cytoplasm.
C. Cole, John J. Scarcelli
2006Current Opinion in Cell Biology140 citations
Semantic Scholar
The Dbp5 cycle at the nuclear pore complex during mRNA export I: dbp5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup159 and Gle1.
C. Hodge, E. Tran, Kristen N Noble, Abel R. Alcázar-Román +6 more
2011Genes & Development105 citations Open access
Semantic Scholar
The yeast integral membrane protein Apq12 potentially links membrane dynamics to assembly of nuclear pore complexes
John J. Scarcelli, C. Hodge, C. Cole
2007Journal of Cell Biology105 citations Open access
Semantic Scholar
Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum
C. Hodge, V. Choudhary, Michael J. Wolyniak, John J. Scarcelli +2 more
2010Journal of Cell Science86 citations Open access
Semantic Scholar
Small-molecule control of antibody N-glycosylation in engineered mammalian cells
Michelle M. Chang, L. Gaidukov, Giyoung Jung, Wen Allen Tseng +16 more
2019Nature Chemical Biology67 citations Open access
Semantic Scholar
Dissecting N-Glycosylation Dynamics in Chinese Hamster Ovary Cells Fed-batch Cultures using Time Course Omics Analyses
M. Sumit, Sepideh Dolatshahi, An-Hsiang Adam Chu, Kaffa Cote +7 more
2019iScience63 citations Open access
Semantic Scholar
Strategic deployment of CHO expression platforms to deliver Pfizer's Monoclonal Antibody Portfolio
John J. Scarcelli, Tanya Q. Shang, Тимоти Искра, Martin J. Allen +1 more
2017Biotechnology progress (Print)49 citations
Semantic Scholar
Transient CHO expression platform for robust antibody production and its enhanced N‐glycan sialylation on therapeutic glycoproteins
Xiao-Tian Zhong, Wei-Jun Ma, Caryl L Meade, A. Tam +20 more
2018Biotechnology progress (Print)44 citations
Semantic Scholar
Synthetic Genetic Array Analysis in Saccharomyces cerevisiae Provides Evidence for an Interaction Between RAT8/DBP5 and Genes Encoding P-Body Components
John J. Scarcelli, S. Viggiano, C. Hodge, C. Heath +2 more
2008Genetics34 citations Open access
Semantic Scholar
Unravelling mRNA export
C. Cole, John J. Scarcelli
2006Nature Cell Biology29 citations
Semantic Scholar
Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease
Xiao-Tian Zhong, S. Jagarlapudi, Yan Weng, Mellisa Ly +27 more
2020Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Analytical subcloning of a clonal cell line demonstrates cellular heterogeneity that does not impact process consistency or robustness
John J. Scarcelli, Megan Hone, K. Beal, Alejaida Ortega +3 more
2018Biotechnology progress (Print)23 citations Open access
Semantic Scholar
The Dbp 5 cycle at the nuclear pore complex during mRNA export I : dbp 5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup 159 and Gle 1
C. Hodge, E. Tran, Kristen N Noble, Abel R. Alcázar-Román +6 more
201121 citations
Semantic Scholar
The impact of expression vector position on transgene transcription allows for rational expression vector design in a targeted integration system
K. Beal, Kalpanie Bandara, Syed R. Ali, Renuka G Sonak +3 more
2023Biotechnology Journal18 citations Open access
Semantic Scholar
Complementation of Essential Yeast GPI Mannosyltransferase Mutations Suggests a Novel Specificity for Certain Trypanosoma and Plasmodium PigB Proteins
Leslie K. Cortes, John J. Scarcelli, C. Taron
2014PLoS ONE15 citations Open access
Semantic Scholar
Genetic rearrangement during site specific integration event facilitates cell line development of a bispecific molecule
Barbara Tevelev, H. Patel, K. Shields, Wei Wei +17 more
2021Biotechnology progress (Print)14 citations Open access
Semantic Scholar
New Opportunities in Glycan Engineering for Therapeutic Proteins
Xiao-Tian Zhong, A. D'Antona, John J. Scarcelli, J. Rouse
2022Antibodies13 citations Open access
Semantic Scholar
Uptake of radiolabeled GlcNAc into Saccharomyces cerevisiae via native hexose transporters and its in vivo incorporation into GPI precursors in cells expressing heterologous GlcNAc kinase
John J. Scarcelli, P. Colussi, A. Fabre, E. Boles +2 more
2012FEMS Yeast Research13 citations Open access
Semantic Scholar
Reactivity-driven cleanup of 2-Aminobenzamide derivatized oligosaccharides.
An-Hsiang Adam Chu, Andrew Saati, John J. Scarcelli, Richard J. Cornell +1 more
2018Analytical Biochemistry12 citations Open access
Semantic Scholar
A high‐fidelity, dual site‐specific integration system in CHO cells by a Bxb1 recombinase
Yi-Feng Xu, Kerstin Crowe, Paulena L. Lieske, Michael R Barnes +5 more
2024Biotechnology Journal8 citations
Semantic Scholar
Impacts of fast production of afucosylated antibodies and Fc mutants in ExpiCHO-S™ for enhancing FcγRIIIa binding and NK cell activation.
Xiao-Tian Zhong, Jennifer Schenk, P. Sakorafas, J. Chamberland +22 more
2022Journal of Biotechnology3 citations Open access
Semantic Scholar
A genetic off‐target event in a site‐specific integration cell line expressing monoclonal antibody has no impact on commercial suitability
Barbara Tevelev, A. Chambers, S. Ghosh, Ying Zhang +5 more
2022Biotechnology progress (Print)2 citations Open access
Semantic Scholar
Improving Multispecific Antibody Bioprocesses Through Coculture and Column‐Based Redox Reactions: Part II
Dawn Eriksen-Stapleton, Michael King, Guo-Gang Dong, Dhruv Srivastava +13 more
2025Biotechnology and Bioengineering1 citations
Semantic Scholar
Impact of Cistron Topology and Bicistronic Vector Design in the piggyBac Transposon System for Improved Antibody Expression
Jason Vitko, Thomas W. King, Efecan Aral, Steven McLellan +7 more
2026Biotechnology Journal0 citations Open access
Semantic Scholar
Evaluation of gene editing in CHO cells using the Cas‐CLOVER system
Tiffany McLamarrah, Efecan Aral, Michael Hoffman, Jennifer Tedstone +10 more
2026Biotechnology progress (Print)0 citations Open access
Semantic Scholar
Expression of GNE mutant proteins increases CHO intracellular CMP-Neu5Ac levels without impact on bioprocess performance
John J. Scarcelli, K. Beal, Robert Hartsough, Jennifer Schenk +5 more
2025Bioprocess and biosystems engineering (Print)0 citations
Semantic Scholar
The relationship between clonality, cellular heterogeneity, and process consistency
John J. Scarcelli, Karin Anderson
20180 citations
Semantic Scholar
Dissecting the Dynamics of N-Linked Glycosylation in Fed-Batch Cultures of Chinese Hamster Ovary Cells Through Time Course Omics Analyses
M. Sumit, Sepideh Dolatshahi, An-Hsiang Adam Chu, Kaffa Cote +7 more
20180 citations Open access
Semantic Scholar

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