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C. Kwok · SciRah

Researcher profile · Semantic Scholar

C. Kwok

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C. Kwok — researcher profile on SciRah

h-index: 10
Works: 24
Citations: 677

Most-cited papers

This Work Is Licensed under a Creative Commons Attribution 3.0 Unported License Combined Myc and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease
Hill Rm, K. S, Li Jc, Petrie K +58 more
166 citations
Semantic Scholar
Recruitment of RXR by homotetrameric RARalpha fusion proteins is essential for transformation.
B. Zeisig, C. Kwok, A. Zelent, P. Shankaranarayanan +3 more
2007Cancer Cell97 citations Open access
Semantic Scholar
Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle
G. Büchel, Anne Carstensen, Ka-Yan Mak, Isabelle Roeschert +15 more
2017Cell Reports88 citations Open access
Semantic Scholar
Forced homo-oligomerization of RARalpha leads to transformation of primary hematopoietic cells.
C. Kwok, B. Zeisig, S. Dong, C. So
2006Cancer Cell67 citations Open access
Semantic Scholar
Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma
E. Poon, Tong Liang, Y. Jamin, S. Walz +39 more
2020Journal of Clinical Investigation57 citations Open access
Semantic Scholar
Transforming activity of AML1-ETO is independent of CBFβ and ETO interaction but requires formation of homo-oligomeric complexes
C. Kwok, B. Zeisig, J. Qiu, S. Dong +1 more
2009Proceedings of the National Academy of Sciences of the United States of America57 citations Open access
Semantic Scholar
In vivo modelling of chemo-resistant neuroblastoma provides new insights into chemo-refractory disease and metastasis.
O. Yogev, G. S. Almeida, K. Barker, Sally L. George +21 more
2019Cancer Research43 citations Open access
Semantic Scholar
Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease
R. Hill, S. Kuijper, J. Lindsey, K. Petrie +28 more
2015Cancer Cell36 citations Open access
Semantic Scholar
MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma
David King, Xiao-Dun Li, G. S. Almeida, C. Kwok +12 more
2020OncoTarget32 citations Open access
Semantic Scholar
The role of CBFbeta in AML1-ETO's activity.
C. Kwok, B. Zeisig, S. Dong, C. So
2009Blood13 citations
Semantic Scholar
Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase
Y. Sbirkov, C. Kwok, Amandeep Bhamra, A. Thompson +3 more
2017International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme
Zuzanna Urban-Wójciuk, A. Graham, K. Barker, C. Kwok +7 more
2021Cancer Gene Therapy4 citations Open access
Semantic Scholar
MIF-CD74 signaling drives immune modulation in medulloblastoma
Benjamin Draper, Zhen You, Dean Thompson, Xu Guo +41 more
2026Neuro-Oncology2 citations Open access
Semantic Scholar
Correction: MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma
David King, Xiao-Dun Li, G. S. Almeida, C. Kwok +12 more
2023OncoTarget2 citations Open access
Semantic Scholar
The role of CBF beta in AML1-ETO's activity. (vol 115, pg 3176, 2010)
C. Kwok, B. Zeisig, S. Dong, C. So
20102 citations
Semantic Scholar
Title : In vivo modelling of chemo-resistant neuroblastoma provides new insights into chemo-refractory disease and metastasis
O. Yogev, Gilberto S. Almeida, Karen T. Barker, Sally L. George +24 more
20191 citations
Semantic Scholar
ID #555 Small molecule drug screening, chemoinformatics and integrative transcriptomics identify targetable MYC-dependent therapeutic vulnerabilities in high-risk medulloblastoma
Louisa Taylor, Bethany Poole, Dean Thompson, Gemma Llargués-Sistac +17 more
2026Neuro-Oncology Pediatrics0 citations Open access
Semantic Scholar
MDB-66. HIGH-THROUGHPUT SMALL MOLECULE DRUG SCREENING, TRANSCRIPTOMICS AND INTEGRATIVE AI IDENTIFY TARGETABLE MYC-DEPENDENT THERAPEUTIC VULNERABILITIES IN HIGH-RISK MEDULLOBLASTOMA
Gemma Llargués-Sistac, Louisa Taylor, J. Lindsey, M. Buttigieg +11 more
2024Neuro-Oncology0 citations Open access
Semantic Scholar
MODL-02. A novelCre-conditionalcMYC-driven MB Group 3 transgenic mouse model shows traceable leptomeningeal dissemination.
A. Morcavallo, K. Barker, C. Kwok, J. Boult +11 more
2022Neuro-Oncology0 citations Open access
Semantic Scholar
TMOD-03. A NOVEL MB GR3 TRANSGENIC MOUSE MODEL IS GENERATED BY MYCN AND P53 DEFECTS IN VENTRICULAR ZONE PROGENITORS.
A. Morcavallo, K. Barker, T. Adachi, J. Boult +9 more
2021Neuro-Oncology0 citations Open access
Semantic Scholar
MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically
R. Hill, S. Kuijper, J. Lindsey, E. Schwalbe +27 more
20140 citations
Semantic Scholar
Transforming Activity of AML1-ETO Oncoprotein Is Independent of CBFβ and ETO but Requires Homo-Oligomeric Interaction.
B. Zeisig, C. Kwok, J. Qiu, S. Dong +1 more
20080 citations
Semantic Scholar
Recruitment of RXRα by Homo-Oligomeric RARα Is a Key for RARα-Mediated Transformation.
B. Zeisig, C. Kwok, Amanda J. Wilson, A. Zelent +3 more
20060 citations
Semantic Scholar
A study of the quaternary structure of human glucose-6-phosphate dehydrogenase (G6PD)
C. Kwok, 郭浩然
20030 citations Open access
Semantic Scholar

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