Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

D. E. Nichols · SciRah

Researcher profile · Semantic Scholar

D. E. Nichols

Share profile

D. E. Nichols — researcher profile on SciRah

h-index: 60
Works: 286
Citations: 19K

Most-cited papers

Psychedelics
D. E. Nichols
2016Pharmacological Reviews1,499 citations Open access
Semantic Scholar
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
J. Urban, W. Clarke, M. von Zastrow, D. E. Nichols +9 more
2007Journal of Pharmacology and Experimental Therapeutics1,155 citations Open access
Semantic Scholar
Serotonin receptors.
D. E. Nichols, Charles D. Nichols
2008Chemical Reviews854 citations
Semantic Scholar
Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor
Kuglae Kim, Tao Che, O. Panova, J. DiBerto +9 more
2020Cell421 citations Open access
Semantic Scholar
Crystal structure of an LSD-bound human serotonin receptor
D. Wacker, Sheng Wang, J. McCorvy, Robin M. Betz +9 more
2017Cell416 citations Open access
Semantic Scholar
Effects of Schedule I drug laws on neuroscience research and treatment innovation
D. Nutt, L. King, D. E. Nichols
2013Nature Reviews Neuroscience313 citations
Semantic Scholar
Molecular Interaction of Serotonin 5-HT2A Receptor Residues Phe339(6.51) and Phe340(6.52) with Superpotent N-Benzyl Phenethylamine Agonists
Michael R. Braden, J. C. Parrish, J. Naylor, D. E. Nichols
2006Molecular Pharmacology217 citations
Semantic Scholar
The G Protein–Biased κ-Opioid Receptor Agonist RB-64 Is Analgesic with a Unique Spectrum of Activities In Vivo
K. White, J. E. Robinson, Hu Zhu, J. DiBerto +5 more
2015Journal of Pharmacology and Experimental Therapeutics198 citations Open access
Semantic Scholar
Microdosing psychedelics: More questions than answers? An overview and suggestions for future research
K. Kuypers, Livia Ng, D. Erritzoe, G. Knudsen +5 more
2019Journal of Psychopharmacology187 citations Open access
Semantic Scholar
WAY-100635 is a potent dopamine D4 receptor agonist
B. Chemel, B. Roth, Blaine N. Armbruster, V. Watts +1 more
2006Psychopharmacology162 citations Open access
Semantic Scholar
Psilocybin: from ancient magic to modern medicine
D. E. Nichols
2020Journal of antibiotics (Tokyo. 1968)148 citations
Semantic Scholar
Psychedelic Drugs in Biomedicine.
E. Kyzar, Charles D. Nichols, R. Gainetdinov, D. E. Nichols +1 more
2017TIPS - Trends in Pharmacological Sciences133 citations
Semantic Scholar
Distinct temporal phases in the behavioral pharmacology of LSD: dopamine D2 receptor-mediated effects in the rat and implications for psychosis
D. Marona-Lewicka, R. Thisted, D. E. Nichols
2005Psychopharmacology126 citations
Semantic Scholar
The History of Psychedelics in Psychiatry
D. E. Nichols, H. Walter
2020Pharmacopsychiatry121 citations Open access
Semantic Scholar
1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agonists.
T. H. Mclean, J. C. Parrish, Michael R. Braden, D. Marona-Lewicka +2 more
2006Journal of Medicinal Chemistry113 citations Open access
Semantic Scholar
A single 20 mg dose of dihydrexidine (DAR-0100), a full dopamine D1 agonist, is safe and tolerated in patients with schizophrenia.
M. George, Christine Molnar, E. Grenesko, B. Anderson +9 more
2007Schizophrenia Research86 citations
Semantic Scholar
A single 20 mg dose of the full D1 dopamine agonist dihydrexidine (DAR-0100) increases prefrontal perfusion in schizophrenia.
Q. Mu, Kevin Johnson, P. Morgan, E. Grenesko +10 more
2007Schizophrenia Research85 citations
Semantic Scholar
Chemistry and Structure-Activity Relationships of Psychedelics.
D. E. Nichols
2018Current topics in behavioral neurosciences84 citations
Semantic Scholar
Sulfur-substituted alpha-alkyl phenethylamines as selective and reversible MAO-A inhibitors: biological activities, CoMFA analysis, and active site modeling.
Alejandra Gallardo-Godoy, A. Fierro, T. H. Mclean, M. Castillo +3 more
2005Journal of Medicinal Chemistry84 citations Open access
Semantic Scholar
Structure–activity relationships of serotonin 5‐HT2A agonists
D. E. Nichols
201277 citations Open access
Semantic Scholar
Is LSD toxic?
D. E. Nichols, C. Grob
2018Forensic Science International74 citations
Semantic Scholar
Differential Activation of Adenylate Cyclase and Receptor Internalization by Novel Dopamine D1 Receptor Agonists
Jessica P. Ryman-Rasmussen, D. E. Nichols, R. Mailman
2005Molecular Pharmacology71 citations
Semantic Scholar
Dark Classics in Chemical Neuroscience: Lysergic Acid Diethylamide (LSD).
D. E. Nichols
2018ACS Chemical Neuroscience69 citations
Semantic Scholar
Assessment of the Roles of Serines 5.43(239) and 5.46(242) for Binding and Potency of Agonist Ligands at the Human Serotonin 5-HT2A Receptor
Michael R. Braden, D. E. Nichols
2007Molecular Pharmacology64 citations
Semantic Scholar
Further evidence that the delayed temporal dopaminergic effects of LSD are mediated by a mechanism different than the first temporal phase of action.
D. Marona-Lewicka, D. E. Nichols
2007Pharmacology, Biochemistry and Behavior63 citations
Semantic Scholar
High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): a high-affinity 5-HT2A receptor-selective agonist radioligand.
D. E. Nichols, Stewart Frescas, B. Chemel, K. Rehder +2 more
2008Bioorganic & Medicinal Chemistry62 citations Open access
Semantic Scholar
N,N-dimethyltryptamine and the pineal gland: Separating fact from myth
D. E. Nichols
2018Journal of Psychopharmacology61 citations
Semantic Scholar
Chronic LSD alters gene expression profiles in the mPFC relevant to schizophrenia
David A. Martin, D. Marona-Lewicka, D. E. Nichols, Charles D. Nichols
2014Neuropharmacology60 citations Open access
Semantic Scholar
AN ANIMAL MODEL OF SCHIZOPHRENIA BASED ON CHRONIC LSD ADMINISTRATION: OLD IDEA, NEW RESULTS
D. Marona-Lewicka, Charles D. Nichols, D. E. Nichols
2011Neuropharmacology60 citations Open access
Semantic Scholar
Entactogens: How the Name for a Novel Class of Psychoactive Agents Originated
D. E. Nichols
2022Frontiers in Psychiatry57 citations Open access
Semantic Scholar
Return of the lysergamides. Part II: Analytical and behavioural characterization of N6-allyl-6-norlysergic acid diethylamide (AL-LAD) and (2’S,4’S)-lysergic acid 2,4-dimethylazetidide (LSZ)
Simon D. Brandt, P. Kavanagh, F. Westphal, S. Elliott +7 more
2016Drug Testing and Analysis55 citations Open access
Semantic Scholar
Extensive rigid analogue design maps the binding conformation of potent N-benzylphenethylamine 5-HT2A serotonin receptor agonist ligands.
J. Juncosa, Martin Hansen, L. Bonner, J. Cueva +5 more
2013ACS Chemical Neuroscience54 citations Open access
Semantic Scholar
Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775)
Simon D. Brandt, P. Kavanagh, B. Twamley, F. Westphal +7 more
2017Drug Testing and Analysis52 citations Open access
Semantic Scholar
Behavioral effects of α,α,β,β-tetradeutero-5-MeO-DMT in rats: comparison with 5-MeO-DMT administered in combination with a monoamine oxidase inhibitor
A. Halberstadt, D. E. Nichols, M. Geyer
2012Psychopharmacology52 citations Open access
Semantic Scholar
The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands.
M. A. Parker, D. Kurrasch, D. E. Nichols
2008Bioorganic & Medicinal Chemistry48 citations Open access
Semantic Scholar
Ambient Temperature Effects on 3,4-Methylenedioxymethamphetamine-Induced Thermodysregulation and Pharmacokinetics in Male Monkeys
M. Banks, J. E. Sprague, D. Kisor, P. Czoty +2 more
2007Drug Metabolism And Disposition45 citations
Semantic Scholar
trans-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline: synthesis, resolution, and preliminary pharmacological characterization of a new dopamine D1 receptor full agonist.
J. Cueva, G. Giorgioni, R. Grubbs, B. Chemel +2 more
2006Journal of Medicinal Chemistry45 citations Open access
Semantic Scholar
α1-Adrenergic Receptors Mediate the Locomotor Response to Systemic Administration of (±)-3,4-Methylenedioxymethamphetamine (MDMA) in rats
Jennifer R. Selken, D. E. Nichols
200743 citations Open access
Semantic Scholar
Dopamine D4 receptor involvement in the discriminative stimulus effects in rats of LSD, but not the phenethylamine hallucinogen DOI
D. Marona-Lewicka, B. Chemel, D. E. Nichols
2009Psychopharmacology40 citations Open access
Semantic Scholar
Differential phospholipase C activation by phenylalkylamine serotonin 5‐HT2A receptor agonists
J. C. Parrish, Michael R. Braden, E. Gundy, D. E. Nichols
2005Journal of Neurochemistry40 citations
Semantic Scholar
Return of the lysergamides. Part III: Analytical characterization of N6-ethyl-6-norlysergic acid diethylamide (ETH-LAD) and 1-propionyl ETH-LAD (1P–ETH-LAD)
Simon D. Brandt, P. Kavanagh, F. Westphal, S. Elliott +4 more
2017Drug Testing and Analysis38 citations Open access
Semantic Scholar
A demand for clarity regarding a case report on the ingestion of 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT) in an Ayahuasca preparation.
J. C. Callaway, C. Grob, D. Mckenna, D. E. Nichols +2 more
2006Journal of Analytical Toxicology34 citations
Semantic Scholar
3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated production of hydrogen peroxide in an in vitro model: the role of dopamine, the serotonin-reuptake transporter, and monoamine oxidase-B.
Sandra L. Hrometz, A. W. Brown, D. E. Nichols, J. E. Sprague
2004Neuroscience Letters34 citations
Semantic Scholar
Understanding Central Nervous System Effects of Deliriant Hallucinogenic Drugs through Experimental Animal Models.
Andrey D. Volgin, O. A. Yakovlev, K. Demin, Polina A. Alekseeva +4 more
2018ACS Chemical Neuroscience33 citations
Semantic Scholar
D1 and functionally selective dopamine agonists as neuroprotective agents in Parkinson's disease.
M. Lewis, X. Huang, D. E. Nichols, R. Mailman
2006CNS and Neurological Disorders - Drug Targets31 citations
Semantic Scholar
Amphetamine derivatives induce locomotor hyperactivity by acting as indirect serotonin agonists
C. W. Callaway, Michael P. Johnson, L. Gold, D. E. Nichols +1 more
2005Psychopharmacology31 citations
Semantic Scholar
WAY 100635 produces discriminative stimulus effects in rats mediated by dopamine D4 receptor activation
D. Marona-Lewicka, D. E. Nichols
2009Behavioural Pharmacology28 citations
Semantic Scholar
'Hybrid' benzofuran-benzopyran congeners as rigid analogs of hallucinogenic phenethylamines.
Danielle M. Schultz, Jennifer A. Prescher, S. Kidd, D. Marona-Lewicka +2 more
2008Bioorganic & Medicinal Chemistry27 citations Open access
Semantic Scholar
C-(4,5,6-trimethoxyindan-1-yl)methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor.
T. H. Mclean, J. Chambers, J. C. Parrish, Michael R. Braden +3 more
2006Journal of Medicinal Chemistry26 citations Open access
Semantic Scholar
Striatal dopamine D1 receptor suppression impairs reward‐associative learning
Kerin K. Higa, Jared W. Young, Baohu Ji, D. E. Nichols +2 more
2017Behavioural Brain Research23 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

D. Marona-Lewicka×10
Invite
D. Marona-Lewicka — researcher profile on SciRah
Charles D. Nichols×5
Invite
Charles D. Nichols — researcher profile on SciRah
Michael R. Braden×5
Invite
Michael R. Braden — researcher profile on SciRah
B. Roth×4
Invite
B. Roth — researcher profile on SciRah

×4

Invite

J. C. Parrish — researcher profile on SciRah

Invite

B. Chemel — researcher profile on SciRah

A. Halberstadt×4

Invite

A. Halberstadt — researcher profile on SciRah

Invite

R. Mailman — researcher profile on SciRah

Invite

J. McCorvy — researcher profile on SciRah

T. H. Mclean×3

Invite

T. H. Mclean — researcher profile on SciRah

Simon D. Brandt×3

Invite

Simon D. Brandt — researcher profile on SciRah

Invite

P. Kavanagh — researcher profile on SciRah