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J. Hellmuth · SciRah

Researcher profile · Semantic Scholar

J. Hellmuth

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J. Hellmuth — researcher profile on SciRah

h-index: 27
Works: 64
Citations: 4,100

Most-cited papers

Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19
T. Herold, V. Jurinovic, Chiara Arnreich, B. Lipworth +4 more
2020Journal of Allergy and Clinical Immunology950 citations Open access
Semantic Scholar
Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy
L. Nicolai, Alexander Leunig, Sophia Brambs, R. Kaiser +18 more
2020Circulation481 citations Open access
Semantic Scholar
5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
A. Schmidt, T. Schwerd, W. Hamm, J. Hellmuth +8 more
2009Proceedings of the National Academy of Sciences of the United States of America444 citations Open access
Semantic Scholar
5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma
H. Poeck, R. Besch, Cornelius Maihoefer, Marcel Renn +27 more
2008Nature Medicine389 citations Open access
Semantic Scholar
Level of IL-6 predicts respiratory failure in hospitalized symptomatic COVID-19 patients
T. Herold, V. Jurinovic, Chiara Arnreich, J. Hellmuth +3 more
2020medRxiv168 citations Open access
Semantic Scholar
The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA
Diana A. Pippig, J. Hellmuth, S. Cui, A. Kirchhofer +5 more
2009Nucleic Acids Research163 citations Open access
Semantic Scholar
Anti–platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein
A. Greinacher, K. Selleng, J. Mayerle, R. Palankar +22 more
2021Blood108 citations Open access
Semantic Scholar
Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19
R. Kaiser, Alexander Leunig, K. Pekayvaz, O. Popp +26 more
2021JCI Insight108 citations Open access
Semantic Scholar
Incorporation of brentuximab vedotin into first-line treatment of advanced classical Hodgkin's lymphoma: final analysis of a phase 2 randomised trial by the German Hodgkin Study Group.
D. Eichenauer, A. Plütschow, S. Kreissl, M. Sökler +13 more
2017The Lancet Oncology102 citations
Semantic Scholar
Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID‐19 from influenza pneumonia
L. Nicolai, Alexander Leunig, Sophia Brambs, R. Kaiser +25 more
2020Journal of Thrombosis and Haemostasis91 citations Open access
Semantic Scholar
Impaired function and delayed regeneration of dendritic cells in COVID-19
Elena Winheim, Linus Rinke, Konstantin Lutz, A. Reischer +20 more
2021bioRxiv87 citations Open access
Semantic Scholar
Liver function test abnormalities at hospital admission are associated with severe course of SARS-CoV-2 infection: a prospective cohort study
S. Weber, J. Hellmuth, C. Scherer, M. Muenchhoff +2 more
2021Gut86 citations Open access
Semantic Scholar
Myocardial Inflammation and Dysfunction in COVID-19-Associated Myocardial Injury.
L. Weckbach, A. Curta, Stéphanie Bieber, A. Kraechan +14 more
2021Circulation Cardiovascular Imaging74 citations
Semantic Scholar
Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles.
J. Hellmuth, A. Louissaint, M. Szczepanowski, S. Haebe +16 more
2018Blood65 citations
Semantic Scholar
Left and right ventricular dysfunction in patients with COVID-19-associated myocardial injury
Stéphanie Bieber, A. Kraechan, J. Hellmuth, M. Muenchhoff +9 more
2021Infection62 citations Open access
Semantic Scholar
CD74 is a functional MIF receptor on activated CD4+ T cells
Lin Zhang, Iris Woltering, Mathias Holzner, Markus Brandhofer +14 more
2024Cellular and Molecular Life Sciences58 citations Open access
Semantic Scholar
Evidence for increased SARS-CoV-2 susceptibility and COVID-19 severity related to pre-existing immunity to seasonal coronaviruses
P. R. Wratil, Niklas A. Schmacke, Burak Karakoc, A. Dulovic +22 more
2021Cell Reports56 citations Open access
Semantic Scholar
Emergence of multiple SARS-CoV-2 mutations in an immunocompromised host
E. Khatamzas, Alexandra Rehn, M. Muenchhoff, J. Hellmuth +13 more
2021medRxiv50 citations Open access
Semantic Scholar
COVID-19 in Patients Receiving CD20-depleting Immunochemotherapy for B-cell Lymphoma
E. Gaitzsch, V. Passerini, E. Khatamzas, C. Strobl +35 more
2021HemaSphere47 citations Open access
Semantic Scholar
Pulmonary function impairment of asymptomatic and persistently symptomatic patients 4 months after COVID-19 according to disease severity
D. Munker, T. Veit, J. Barton, P. Mertsch +13 more
2021Infection45 citations Open access
Semantic Scholar
Rational targeting of cooperating layers of the epigenome yields enhanced therapeutic efficacy against AML
C. Duy, Matt Teater, F. Garrett-Bakelman, Tak C. Lee +19 more
2019Cancer Discovery44 citations Open access
Semantic Scholar
Dynamics of SARS-CoV-2 shedding in the respiratory tract depends on the severity of disease in COVID-19 patients
D. Munker, Andreas Osterman, H. Stubbe, M. Muenchhoff +20 more
2021European Respiratory Journal41 citations Open access
Semantic Scholar
Targeted Beacopp Variants In Patients With Newly Diagnosed Advanced Stage Classical Hodgkin Lymphoma: Interim Results Of a Randomized Phase II Study
P. Borchmann, D. Eichenauer, A. Pluetschow, H. Haverkamp +11 more
201339 citations
Semantic Scholar
Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection
K. Pekayvaz, Alexander Leunig, R. Kaiser, M. Joppich +40 more
2022Nature Communications35 citations Open access
Semantic Scholar
Polymorphisms in MDA-5 link protein function to clearance of hepatitis C virus
F. Hoffmann, A. Schmidt, M. Chevillotte, Christian Wisskirchen +14 more
2015Hepatology35 citations Open access
Semantic Scholar
Unique immune cell coactivators specify locus control region function and cell stage
Chi-Shuen Chu, J. Hellmuth, Rajat Singh, Hsia-Yuan Ying +6 more
2020Molecules and Cells28 citations Open access
Semantic Scholar
Sequential therapy combining clofarabine and T-cell-replete HLA-haploidentical haematopoietic SCT is feasible and shows efficacy in the treatment of refractory or relapsed aggressive lymphoma
A. Zoellner, S. Fritsch, Dusan Prevalsek, N. Engel +12 more
2015Bone Marrow Transplantation28 citations Open access
Semantic Scholar
Binding of phosphatidylserine‐positive microparticles by PBMCs classifies disease severity in COVID‐19 patients
Lisa Rausch, Konstantin Lutz, M. Schifferer, Elena Winheim +13 more
2021bioRxiv27 citations Open access
Semantic Scholar
Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infection
E. Khatamzas, Markus H. Antwerpen, Alexandra Rehn, A. Graf +26 more
2022Nature Communications21 citations Open access
Semantic Scholar
Anti-SARS-CoV-2 Spike Protein and Anti-Platelet Factor 4 Antibody Responses Induced by COVID-19 Disease and ChAdOx1 nCov-19 vaccination
A. Greinacher, K. Selleng, J. Mayerle, R. Palankar +22 more
202121 citations Open access
Semantic Scholar
OCT2 pre-positioning facilitates cell fate transition and chromatin architecture changes in humoral immunity
A. Doane, Chi-Shuen Chu, D. C. Di Giammartino, M. Rivas +8 more
2021Nature Immunology19 citations Open access
Semantic Scholar
The course of subjective and objective chemosensory dysfunction in hospitalized patients with COVID-19: a 6-month follow-up
M. Bertlich, Clemens Stihl, E. Lüsebrink, J. Hellmuth +8 more
2021European Archives of Oto-Rhino-Laryngology16 citations Open access
Semantic Scholar
Impact of age on genetics and treatment efficacy in follicular lymphoma
S. Alig, V. Jurinovic, A. Pastore, D. Bararia +12 more
2018Haematologica13 citations Open access
Semantic Scholar
Genomic epidemiology reveals multiple introductions of SARS-CoV-2 followed by community and nosocomial spread, Germany, February to May 2020
M. Muenchhoff, A. Graf, S. Krebs, Caroline Quartucci +34 more
2021Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin11 citations Open access
Semantic Scholar
Quantitation of SARS-CoV-2 neutralizing antibodies with a virus-free, authentic test
Johannes Roessler, D. Pich, M. Albanese, P. R. Wratil +9 more
2021medRxiv11 citations Open access
Semantic Scholar
Proteomics reveals antiviral host response and NETosis during acute COVID-19 in high-risk patients
A. Bauer, E. Pachl, J. Hellmuth, N. Kneidinger +15 more
2022Biochimica et Biophysica Acta - Molecular Basis of Disease10 citations Open access
Semantic Scholar
Thyroidal Angiotensin-Converting Enzyme 2 Protein Expression and Thyroid Function Tests in Patients with COVID-19: Results from a Retrospective Case Series and a Prospective Cohort Study
V. F. Koehler, T. Knösel, S. Hasmann, C. Scherer +6 more
2022Thyroid10 citations
Semantic Scholar
Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients
Carolin E. M. Koll, Sina M. Hopff, T. Meurers, Chin-Huang Lee +22 more
2022Scientific Data9 citations Open access
Semantic Scholar
Evaluating upfront high-dose consolidation after R-CHOP for follicular lymphoma by clinical and genetic risk models.
S. Alig, V. Jurinovic, Mohammad Shahrokh Esfahani, S. Haebe +22 more
2020Blood Advances9 citations Open access
Semantic Scholar
Differences in Cardiac Magnetic Resonance Imaging Markers Between Patients With COVID-19-associated Myocardial Injury and Patients With Clinically Suspected Myocarditis
S. Maurus, L. Weckbach, C. Marschner, W. Kunz +10 more
2021Journal of thoracic imaging7 citations Open access
Semantic Scholar
Dynamics of urinary and respiratory shedding of Severe acute respiratory syndrome virus 2 (SARS-CoV-2) RNA excludes urine as a relevant source of viral transmission
Jan-Niclas Mumm, S. Ledderose, A. Ostermann, M. Rudelius +19 more
2021Infection7 citations Open access
Semantic Scholar
Risk Stratification Based on a Pattern of Immunometabolic Host Factors Is Superior to Body Mass Index—Based Prediction of COVID-19-Associated Respiratory Failure
D. M. Cordas dos Santos, Lian Liu, Melvin Gerisch, J. Hellmuth +3 more
2022Nutrients6 citations Open access
Semantic Scholar
Vitronectin promotes immunothrombotic dysregulation in the venular microvasculature
B. Uhl, F. Haring, J. Slotta-Huspenina, Joshua Luft +19 more
2023Frontiers in Immunology4 citations Open access
Semantic Scholar
Analysis of acute COVID-19 including chronic morbidity: protocol for the deep phenotyping National Pandemic Cohort Network in Germany (NAPKON-HAP)
F. Steinbeis, C. Thibeault, S. Steinbrecher, Yvonne Ahlgrimm +79 more
2023Infection4 citations Open access
Semantic Scholar
How to exclude pulmonary embolism in patients hospitalized with COVID-19: a comparison of predictive scores
J. Vielhauer, Christopher Benesch, A. Pernpruner, Anna-Lena Johlke +9 more
2023Thrombosis Journal4 citations Open access
Semantic Scholar
Impaired immune responses and prolonged viral replication in lung allograft recipients infected with SARS-CoV-2 in the early phase after transplantation
O. Glueck, Xiao-Ling Liang, I. Badell, P. R. Wratil +15 more
2023Infection3 citations Open access
Semantic Scholar
T002: Treatment related morbidity in patients with classical Hodgkin Lymphoma: results of the ongoing, randomized phase III HD21 Trial by The German Hodgkin Study Group
P. Borchmann, A. Moccia, R. Greil, M. Herzberg +26 more
2022HemaSphere3 citations Open access
Semantic Scholar
Distinct and dynamic activation profiles of circulating dendritic cells and monocytes in mild COVID‐19 and after yellow fever vaccination
Elena Winheim, T. Eser, F. Déak, Mohamed I. M. Ahmed +17 more
2022European Journal of Immunology3 citations Open access
Semantic Scholar
CD8 T cells and antibodies drive SARS-CoV-2 evolution in chronic infection
E. Khatamzas, M. Muenchhoff, Alexandra Rehn, A. Graf +26 more
20213 citations Open access
Semantic Scholar
Self-sustaining interleukin-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19
R. Kaiser, L. Nicolai, Konstantin Stark, Alexander Leunig +26 more
20213 citations
Semantic Scholar

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