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R. Besch · SciRah

Researcher profile · Semantic Scholar

R. Besch

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R. Besch — researcher profile on SciRah

h-index: 24
Works: 53
Citations: 3,468

Most-cited papers

5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
A. Schmidt, T. Schwerd, W. Hamm, J. Hellmuth +8 more
2009Proceedings of the National Academy of Sciences of the United States of America444 citations Open access
Semantic Scholar
Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells.
R. Besch, H. Poeck, Tobias Hohenauer, D. Senft +7 more
2009Journal of Clinical Investigation443 citations Open access
Semantic Scholar
Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions
Y. Dombrowski, M. Perić, S. Koglin, C. Kammerbauer +10 more
2011Science Translational Medicine435 citations Open access
Semantic Scholar
5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma
H. Poeck, R. Besch, Cornelius Maihoefer, Marcel Renn +27 more
2008Nature Medicine389 citations Open access
Semantic Scholar
Melanocyte antigen triggers autoimmunity in human psoriasis
A. Arakawa, K. Siewert, J. Stöhr, P. Besgen +13 more
2015Journal of Experimental Medicine346 citations Open access
Semantic Scholar
IL-17A Enhances Vitamin D3-Induced Expression of Cathelicidin Antimicrobial Peptide in Human Keratinocytes
M. Perić, S. Koglin, Song-Min Kim, S. Morizane +5 more
2008Journal of Immunology186 citations Open access
Semantic Scholar
Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells
A. Weber, Z. Kirejczyk, R. Besch, S. Potthoff +2 more
2010Cell Death and Differentiation154 citations
Semantic Scholar
SOX10 promotes melanoma cell invasion by regulating melanoma inhibitory activity.
S. Graf, C. Busch, A. Bosserhoff, R. Besch +1 more
2014Journal of Investigative Dermatology86 citations Open access
Semantic Scholar
Differential expression of melanoma‐associated growth factors in keratinocytes and fibroblasts by ultraviolet A and ultraviolet B radiation
M. Brenner, K. Degitz, R. Besch, C. Berking
2005British Journal of Dermatology79 citations
Semantic Scholar
Targeting the Cytosolic Innate Immune Receptors RIG‐I and MDA5 Effectively Counteracts Cancer Cell Heterogeneity in Glioblastoma
M. Glas, C. Coch, Daniel Trageser, Juliane Dassler +18 more
2013Stem Cells74 citations
Semantic Scholar
Nestin and SOX9 and SOX10 transcription factors are coexpressed in melanoma
R. Bakos, T. Maier, R. Besch, Dominik S. Mestel +3 more
2009Experimental Dermatology71 citations
Semantic Scholar
Immunostimulatory RNA Blocks Suppression by Regulatory T Cells
D. Anz, Viktor H. Koelzer, S. Moder, Raffael Thaler +10 more
2009Journal of Immunology64 citations Open access
Semantic Scholar
Selective Induction of Cell Death in Melanoma Cell Lines through Targeting of Mcl-1 and A1
D. Senft, C. Berking, S. Graf, C. Kammerbauer +2 more
2012PLoS ONE59 citations Open access
Semantic Scholar
SOX9 and SOX10 but not BRN2 are required for nestin expression in human melanoma cells.
A. Flammiger, R. Besch, A. Cook, T. Maier +2 more
2009Journal of Investigative Dermatology57 citations Open access
Semantic Scholar
Triplex-forming oligonucleotides - sequence-specific DNA ligands as tools for gene inhibition and for modulation of DNA-associated functions.
R. Besch, C. Giovannangeli, K. Degitz
2004Current Drug Targets55 citations
Semantic Scholar
Inhibition of spring viraemia of carp virus replication in an Epithelioma papulosum cyprini cell line by RNAi
M. Gotesman, H. Soliman, R. Besch, M. El-Matbouli
2014Journal of Fish Diseases54 citations Open access
Semantic Scholar
Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1
H. Zall, A. Weber, R. Besch, N. Zantl +1 more
2010Molecular Cancer54 citations Open access
Semantic Scholar
Inhibition of urokinase-type plasminogen activator receptor induces apoptosis in melanoma cells by activation of p53
R. Besch, C. Berking, C. Kammerbauer, K. Degitz
2007Cell Death and Differentiation47 citations
Semantic Scholar
Specific Inhibition of ICAM-1 Expression Mediated by Gene Targeting with Triplex-forming Oligonucleotides*
R. Besch, C. Giovannangeli, C. Kammerbauer, K. Degitz
2002Journal of Biological Chemistry37 citations Open access
Semantic Scholar
MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression
M. Heppt, Joshua X. Wang, D. Hristova, Zhi Wei +14 more
2017Journal of Investigative Dermatology36 citations Open access
Semantic Scholar
The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival
Tobias Hohenauer, C. Berking, A. Schmidt, S. Haferkamp +15 more
2013EMBO Molecular Medicine36 citations Open access
Semantic Scholar
Gene Therapy for Advanced Melanoma: Selective Targeting and Therapeutic Nucleic Acids
Joana R. Viola, D. Rafael, E. Wagner, R. Besch +1 more
2013Journal of Drug Delivery30 citations Open access
Semantic Scholar
Characterization and quantification of triple helix formation in chromosomal DNA.
R. Besch, C. Giovannangeli, Theda Schuh, C. Kammerbauer +1 more
2004Journal of Molecular Biology27 citations
Semantic Scholar
POU transcription factors in melanocytes and melanoma.
R. Besch, C. Berking
2014European Journal of Cell Biology25 citations
Semantic Scholar
The CDKN2A p.A148T variant is associated with cutaneous melanoma in Southern Brazil
R. Bakos, R. Besch, Gabriela Zoratto, Janaína M. Godinho +7 more
2011Experimental Dermatology24 citations
Semantic Scholar
In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins
D. Senft, A. Weber, F. Saathoff, C. Berking +7 more
2015Cell Death and Disease23 citations Open access
Semantic Scholar
In vitro inhibition of Cyprinid herpesvirus-3 replication by RNAi
M. Gotesman, H. Soliman, R. Besch, M. El-Matbouli
2014Journal of Virological Methods23 citations Open access
Semantic Scholar
Cytosolic DNA Triggers Mitochondrial Apoptosis via DNA Damage Signaling Proteins Independently of AIM2 and RNA Polymerase III
M. Wenzel, M. Wunderlich, R. Besch, H. Poeck +7 more
2012Journal of Immunology20 citations Open access
Semantic Scholar
Second generation of diazachrysenes: Protection of Ebola virus infected mice and mechanism of action.
Života Selaković, Julie P. Tran, Krishna P. Kota, Marija Lazić +14 more
2019European journal of medicinal chemistry17 citations Open access
Semantic Scholar
Protease Inhibitors Prevent Plasminogen-Mediated, But Not Pemphigus Vulgaris-Induced, Acantholysis in Human Epidermis
Theda Schuh, R. Besch, Evelyn Braungart, M. J. Flaig +6 more
2003Biological chemistry14 citations Open access
Semantic Scholar
The spectrum of Malassezia species isolated from students with pityriasis vesicolor in Nigeria
P. Ibekwe, A. Ogunbiyi, R. Besch, T. Ruzicka +1 more
2015Mycoses (Berlin)12 citations
Semantic Scholar
HDAC2 Is Involved in the Regulation of BRN3A in Melanocytes and Melanoma
M. Heppt, A. Wessely, E. Hornig, C. Kammerbauer +8 more
2022International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Triple helix-mediated inhibition of gene expression is increased by PUVA.
R. Besch, Christoph Marschall, Theda Schuh, C. Giovannangeli +2 more
2004Journal of Investigative Dermatology11 citations Open access
Semantic Scholar
A Bifunctional Approach of Immunostimulation and uPAR Inhibition Shows Potent Antitumor Activity in Melanoma.
Fanny Matheis, M. Heppt, S. Graf, P. Düwell +4 more
2016Journal of Investigative Dermatology10 citations Open access
Semantic Scholar
Pathogenic DNA: Cytosolic DNA promotes inflammation in psoriasis
J. Schauber, Y. Dombrowski, R. Besch
2011Cell Cycle10 citations Open access
Semantic Scholar
Bifunctional siRNAs for tumor therapy.
Fanny Matheis, R. Besch
2014Methods in molecular biology3 citations
Semantic Scholar
5 (cid:1) -triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
Andreas Schmidt, T. Schwerd, W. Hamm, J. Hellmuth +8 more
3 citations
Semantic Scholar
Expression of BRN2, osteopontin and nestin in melanoma and nevi. New markers of tumor progression?
T. Maier, D. Mestel, R. Besch, U. Nagele +2 more
20062 citations
Semantic Scholar
MSX1 promotes melanoma progression via neural crest-like reprogramming
M. Fukunaga-Kalabis, M. Heppt, Joshua X. Wang, D. Hristova +8 more
20161 citations
Semantic Scholar
Entwicklung und Anwendung eines in vitro Co-Kultur-Modells der Haut zur Identifizierung potentieller Therapeutika bei Schwefellost-Vergiftungen Development and Application of a in vitro Co-Culture Model of the Skin for the Identificaton of Therapeutics against Sulfur Mustard Intoxications
T. Gudermann, R. Besch, O. Peschel
20180 citations
Semantic Scholar
Freie Vorträge
M. Heppt, Fanny Matheis, C. Kammerbauer, P. Düwell +4 more
2016Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG0 citations Open access
Semantic Scholar
The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion
S. Graf, S. Krebs, Helmut Blum, E. Hornig +4 more
20160 citations
Semantic Scholar
Abstract A13: MSX1-induced neural crest-like reprograming promotes melanoma progression
M. Heppt, W. Joshua, D. Hristova, Wei Zhi +8 more
20150 citations
Semantic Scholar
Psoriatic Lesions Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in
Y. Dombrowski, M. Perić, S. Koglin, C. Kammerbauer +10 more
20110 citations
Semantic Scholar
This information is current as Polymerase III Proteins Independently of AIM 2 and RNA Apoptosis via DNA Damage Signaling Cytosolic DNA Triggers Mitochondrial
Michael Wenzel, M. Wunderlich, R. Besch, H. Poeck +7 more
20110 citations
Semantic Scholar
This information is current as by Regulatory T Cells Immunostimulatory RNA Blocks Suppression
D. Anz, Viktor H. Koelzer, S. Moder, Raffael Thaler +10 more
20090 citations
Semantic Scholar
Characterization of NF-kappaB activity and functional analysis of p65 in melanoma
I. H. bert, C. Berking, C. Kammerbauer, K. Degitz +1 more
20060 citations
Semantic Scholar
Inhibition of urokinase-type plasminogen activator receptor activates p53 and induces apoptosis in melanoma
R. Besch, C. Berking, C. Kammerbauer, K. Degitz
20060 citations
Semantic Scholar
Expression of BRN2, osteopontin and nestin in melanoma and nevi as indicators for tumor progression
T. Maier, A. Flammiger, D. Mestel, R. Besch +2 more
20060 citations
Semantic Scholar
Characterization of the role of CDC91L1 expression in melanoma
Tobias Hohenauer, C. Berking, C. Kammerbauer, K. Degitz +1 more
20060 citations
Semantic Scholar

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