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P. Arkwright · SciRah

Researcher profile · Semantic Scholar

P. Arkwright

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P. Arkwright — researcher profile on SciRah

h-index: 69
Works: 260
Citations: 15K

Most-cited papers

Type 2 immunity in the skin and lungs
C. Akdis, P. Arkwright, Marie-Charlotte Brüggen, W. Busse +7 more
2020Allergy. European Journal of Allergy and Clinical Immunology512 citations Open access
Semantic Scholar
Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number
Jonathan J. Lyons, Xiao-Min Yu, J. Hughes, Quang T. Le +32 more
2016Nature Genetics338 citations Open access
Semantic Scholar
Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: a randomized, double-blinded, placebo-controlled phase 3 trial.
A. Paller, E. Siegfried, D. Thaçi, A. Wollenberg +21 more
2020Journal of American Academy of Dermatology318 citations Open access
Semantic Scholar
Phenotype, penetrance, and treatment of 133 CTLA-4-insufficient subjects
C. Schwab, Annemarie Gabrysch, P. Olbrich, V. Patiño +77 more
2018Journal of Allergy and Clinical Immunology262 citations Open access
Semantic Scholar
Biallelic RIPK1 mutations in humans cause severe immunodeficiency, arthritis and intestinal inflammation
Delphine Cuchet-Lourenço, Davide Eletto, Changxing Wu, V. Plagnol +19 more
2018Science211 citations Open access
Semantic Scholar
Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial.
A. Paller, E. Simpson, E. Siegfried, M. Cork +23 more
2022The Lancet191 citations Open access
Semantic Scholar
The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach
M. Greenhawt, E. Abrams, M. Shaker, Derek K. Chu +59 more
2021Journal of Allergy and Clinical Immunology: In Practice191 citations Open access
Semantic Scholar
Phenotype, penetrance, and treatment of 133 CTLA-1 4-insufficient individuals
P. Arkwright
2018146 citations
Semantic Scholar
Hypomorphic CARD11 mutations associated with diverse immunologic phenotypes with or without atopic disease.
Batsukh Dorjbal, J. Stinson, Chi A. Ma, M. Weinreich +51 more
2018Journal of Allergy and Clinical Immunology123 citations Open access
Semantic Scholar
Therapeutic options for CTLA-4 Insufficiency.
D. Egg, I. Rump, N. Mitsuiki, J. Rojas-Restrepo +72 more
2021Journal of Allergy and Clinical Immunology114 citations Open access
Semantic Scholar
Inherited p40phox deficiency differs from classic chronic granulomatous disease
A. van de Geer, A. Nieto-Patlán, D. Kuhns, A. Tool +55 more
2018Journal of Clinical Investigation105 citations Open access
Semantic Scholar
Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations.
T. Hou, N. Verma, J. Wanders, A. Kennedy +16 more
2017Blood100 citations Open access
Semantic Scholar
Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes
Maximilian Witzel, Daniel Petersheim, Yanxin Fan, E. Bahrami +20 more
2017Nature Genetics97 citations Open access
Semantic Scholar
Increased Risk for Malignancies in 131 Affected CTLA4 Mutation Carriers
D. Egg, C. Schwab, Annemarie Gabrysch, P. Arkwright +18 more
2018Frontiers in Immunology95 citations Open access
Semantic Scholar
Hereditary Alpha-Tryptasemia: UK Prevalence and variability in disease expression.
Rebecca C. Robey, A. Wilcock, H. Bonin, G. Beaman +4 more
2020Journal of Allergy and Clinical Immunology: In Practice93 citations
Semantic Scholar
Hematopoietic stem cell transplantation for CTLA4 deficiency.
M. Slatter, K. Engelhardt, L. Burroughs, P. Arkwright +13 more
2016Journal of Allergy and Clinical Immunology93 citations Open access
Semantic Scholar
Phase 3 Trial of Epicutaneous Immunotherapy in Toddlers with Peanut Allergy.
M. Greenhawt, S. Sindher, Julie Wang, M. O'Sullivan +62 more
2023New England Journal of Medicine92 citations Open access
Semantic Scholar
Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets
Cindy S. Ma, Natalie Wong, G. Rao, A. Nguyen +42 more
2016Journal of Experimental Medicine92 citations Open access
Semantic Scholar
An integrated taxonomy for monogenic inflammatory bowel disease
C. Bolton, C. Smillie, S. Pandey, R. Elmentaite +32 more
2021Gastroenterology88 citations Open access
Semantic Scholar
DOCK8-DEFICIENT CD4+ T CELLS ARE BIASED TO A TH2 EFFECTOR FATE AT THE EXPENSE OF TH1 AND TH17 CELLS
S. Tangye, Bethany A. Pillay, Katrina L. Randall, D. Avery +15 more
2016Journal of Allergy and Clinical Immunology88 citations Open access
Semantic Scholar
Human adaptive immunity rescues an inborn error of innate immunity
Laura Israel, Ying Wang, K. Bulek, E. Della Mina +30 more
2017Cell82 citations Open access
Semantic Scholar
Defective Leukocyte Adhesion and Chemotaxis Contributes to Combined Immunodeficiency in Humans with Autosomal Recessive MST1 Deficiency
Tarana Singh Dang, Joseph D. P. Willet, H. Griffin, N. Morgan +14 more
2016Journal of Clinical Immunology74 citations Open access
Semantic Scholar
Mast cell disorders: From infancy to maturity
A. Wilcock, R. Bahri, S. Bulfone-Paus, P. Arkwright
2018Allergy. European Journal of Allergy and Clinical Immunology63 citations Open access
Semantic Scholar
Staphylococcus aureus Second Immunoglobulin-Binding Protein drives atopic dermatitis via IL-33.
Arwa Al Kindi, H. Williams, Kenshiro Matsuda, Abdullah M. Alkahtani +9 more
2020Journal of Allergy and Clinical Immunology61 citations Open access
Semantic Scholar
Clinical and laboratory features of seventy‐eight UK patients with Good’s syndrome (thymoma and hypogammaglobulinaemia)
M. Zaman, A. Huissoon, M. Buckland, Smita Y. Patel +11 more
2018Clinical and Experimental Immunology58 citations Open access
Semantic Scholar
14 Years after Discovery: Clinical Follow-up on 15 Patients with Inducible Co-Stimulator Deficiency
J. Schepp, J. Chou, A. Skrabl-Baumgartner, P. Arkwright +7 more
2017Frontiers in Immunology58 citations Open access
Semantic Scholar
Staphylococcus aureus Internalized by Skin Keratinocytes Evade Antibiotic Killing
Arwa Al Kindi, Abdullah M. Alkahtani, M. Nalubega, C. El‐Chami +3 more
2019Frontiers in Microbiology57 citations Open access
Semantic Scholar
Genetic, immunological, and clinical features of 32 patients with autosomal recessive STAT1 deficiency
T. Le Voyer, Sonoko Sakata, M. Tsumura, Taushif Khan +43 more
2021Journal of Immunology53 citations Open access
Semantic Scholar
Dupilumab Safety and Efficacy in a Phase III Open-Label Extension Trial in Children 6–11 Years of Age with Severe Atopic Dermatitis
M. Cork, D. Thaçi, L. Eichenfield, P. Arkwright +7 more
2023Dermatologic Therapy38 citations Open access
Semantic Scholar
Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation.
Emmanuel Martin, N. Minet, Anne-Claire Boschat, S. Sanquer +16 more
2020JCI Insight38 citations Open access
Semantic Scholar
Severity and threshold of peanut reactivity during hospital‐based open oral food challenges: An international multicenter survey
P. Arkwright, J. MacMahon, J. Koplin, Shelly Rajput +14 more
2018Pediatric Allergy and Immunology38 citations Open access
Semantic Scholar
Hematopoietic stem cell transplant effectively rescues lymphocyte differentiation and function in DOCK8-deficient patients.
Bethany A. Pillay, D. Avery, Joanne M. Smart, Theresa Cole +25 more
2019JCI Insight36 citations Open access
Semantic Scholar
Immunodeficiency, autoimmune thrombocytopenia and enterocolitis caused by autosomal recessive deficiency of PIK3CD-encoded phosphoinositide 3-kinase δ
D. Swan, D. Aschenbrenner, C. Lamb, Krishnendu Chakraborty +16 more
2019Haematologica32 citations Open access
Semantic Scholar
Bronchiectasis and deteriorating lung function in agammaglobulinaemia despite immunoglobulin replacement therapy
A. Stubbs, C. Bangs, B. Shillitoe, J. Edgar +9 more
2018Clinical and Experimental Immunology31 citations Open access
Semantic Scholar
Skin pH is the Master Switch of Kallikrein 5-Mediated Skin Barrier Destruction in a Murine Atopic Dermatitis Model
H. Jang, A. Matsuda, K. Jung, Kaoru Karasawa +11 more
201530 citations
Semantic Scholar
Mast cell hyperactivity underpins the development of oxygen-induced retinopathy
Kenshiro Matsuda, N. Okamoto, Masatoshi Kondo, P. Arkwright +17 more
2017Journal of Clinical Investigation28 citations Open access
Semantic Scholar
DOCK11 deficiency in patients with X-linked actinopathy and autoimmunity.
C. Boussard, Laure Delage, Tania Gajardo, A. Kauskot +54 more
2023Blood27 citations Open access
Semantic Scholar
Impact of a decade of research into atopic dermatitis.
P. Arkwright, J. Koplin
2022Journal of Allergy and Clinical Immunology: In Practice26 citations Open access
Semantic Scholar
The deep fascia of the thigh forms an impenetrable barrier to fluid injected subcutaneously by autoinjectors.
Daniela Diacono, R. Pumphrey, Vibha Sharma, P. Arkwright
2015Journal of Allergy and Clinical Immunology: In Practice24 citations
Semantic Scholar
Laboratory Safety of Dupilumab in Patients Aged 6–11 Years with Severe Atopic Dermatitis: Results from a Phase III Clinical Trial
A. Paller, A. Wollenberg, E. Siegfried, D. Thaçi +11 more
2021Pediatric Drugs23 citations Open access
Semantic Scholar
Laboratory Safety from a Randomized 16-Week Phase III Study of Dupilumab in Children Aged 6 Months to 5 Years with Moderate-to-Severe Atopic Dermatitis
A. Paller, E. Siegfried, M. Cork, A. Wollenberg +7 more
2022Pediatric Drugs17 citations Open access
Semantic Scholar
Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia
S. Zielen, R. Duecker, S. Woelke, H. Donath +49 more
2021Journal of Clinical Immunology17 citations Open access
Semantic Scholar
Neutrophil dysfunction triggers inflammatory bowel disease in G6PC3 deficiency
A. Goenka, John A. Doherty, Tariq Al-Farsi, C. Jagger +7 more
2020Journal of Leukocyte Biology17 citations Open access
Semantic Scholar
Infant Alveolar Macrophages Are Unable to Effectively Contain Mycobacterium tuberculosis
A. Goenka, Ian E. Prise, E. Connolly, Paulina Fernandez-Soto +6 more
2020Frontiers in Immunology17 citations Open access
Semantic Scholar
Factors that determine parents' perception of their child's risk of life-threatening food-induced anaphylaxis.
Jennifer Ogg, J. Wong, Ming W. Wan, N. Davis +1 more
2017Allergy and Asthma Proceedings17 citations Open access
Semantic Scholar
A national survey of hereditary angioedema and acquired C1 inhibitor deficiency in the United Kingdom.
P. Yong, T. Coulter, Tariq El-Shanwany, T. Garcez +45 more
2023Journal of Allergy and Clinical Immunology: In Practice16 citations Open access
Semantic Scholar
Bone marrow transplantation for MHC class I deficiency corrects T-cell immunity but dissociates natural killer cell repertoire formation from function
Yifang Gao, P. Arkwright, R. Carter, Angelica M. Cazaly +7 more
2016Journal of Allergy and Clinical Immunology16 citations Open access
Semantic Scholar
Regional risk of tuberculosis and viral hepatitis with tumor necrosis factor-alpha inhibitor treatment: A systematic review
Nina Jahnich, P. Arkwright
2023Frontiers in Pharmacology14 citations Open access
Semantic Scholar
Hematopoietic stem cell transplantation for cytidine triphosphate synthase 1 (CTPS1) deficiency
Z. Nademi, R. Wynn, M. Slatter, S. Hughes +11 more
2018Bone Marrow Transplantation14 citations Open access
Semantic Scholar
Dupilumab Treatment Leads to Rapid and Consistent Improvement of Atopic Dermatitis in All Anatomical Regions in Patients Aged 6 Months to 5 Years
E. Siegfried, E. Simpson, M. Cork, P. Arkwright +6 more
2023Dermatologic Therapy13 citations Open access
Semantic Scholar

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