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G. Rao · SciRah

Researcher profile · Semantic Scholar

G. Rao

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G. Rao — researcher profile on SciRah

h-index: 27
Works: 59
Citations: 2,577

Most-cited papers

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome
A. Kreins, Michael J. Ciancanelli, S. Okada, Xiao-Fei Kong +50 more
2015Journal of Experimental Medicine323 citations Open access
Semantic Scholar
Monogenic mutations differentially impact the quantity and quality of T follicular helper cells in human primary immunodeficiencies
Cindy S. Ma, Natalie Wong, G. Rao, D. Avery +46 more
2015Journal of Allergy and Clinical Immunology191 citations Open access
Semantic Scholar
Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant
S. Boisson-Dupuis, Noé Ramírez-Alejo, Zhi Li, E. Patin +63 more
2018Science immunology188 citations Open access
Semantic Scholar
Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23
R. Martinez-Barricarte, J. Markle, Cindy S. Ma, E. Deenick +49 more
2018Science immunology173 citations Open access
Semantic Scholar
A recessive form of Hyper IgE Syndrome by disruption of ZNF341-dependent STAT3 transcription and activity
V. Béziat, Juan Li, Jian-Xin Lin, Cindy S. Ma +57 more
2018Science immunology164 citations Open access
Semantic Scholar
Heparanase-1 gene expression and regulation by high glucose in renal epithelial cells: a potential role in the pathogenesis of proteinuria in diabetic patients.
J. Maxhimer, M. Somenek, G. Rao, C. Pesce +6 more
2005Diabetes122 citations Open access
Semantic Scholar
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child
Masato Ogishi, Rui Yang, C. Aytekin, D. Langlais +51 more
2021Nature Medicine96 citations Open access
Semantic Scholar
Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets
Cindy S. Ma, Natalie Wong, G. Rao, A. Nguyen +42 more
2016Journal of Experimental Medicine92 citations Open access
Semantic Scholar
Disruption of an anti-mycobacterial circuit between dendritic and Th cells in human SPPL2a deficiency
Xiao-Fei Kong, R. Martinez-Barricarte, J. Kennedy, F. Mele +37 more
2018Nature Immunology88 citations Open access
Semantic Scholar
STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function
R. Wilson, Megan L. Ives, G. Rao, A. Lau +24 more
2015Journal of Experimental Medicine85 citations Open access
Semantic Scholar
Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy
V. Béziat, Franck Rapaport, Jiafen Hu, M. Titeux +70 more
2021Cell80 citations Open access
Semantic Scholar
Major histocompatibility complex class I-related chain A/B (MICA/B) expression in tumor tissue and serum of pancreatic cancer: Role of uric acid accumulation in gemcitabine-induced MICA/B expression
Xiulong Xu, G. Rao, V. Groh, T. Spies +4 more
2011BMC Cancer77 citations Open access
Semantic Scholar
Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency.
Sujal Ghosh, Sevgi Kostel Bal, E. Edwards, Bethany A. Pillay +64 more
2020Blood75 citations Open access
Semantic Scholar
Reactive oxygen species mediate high glucose-induced heparanase-1 production and heparan sulphate proteoglycan degradation in human and rat endothelial cells: a potential role in the pathogenesis of atherosclerosis
G. Rao, H. Ding, W. Huang, D. Le +8 more
2011Diabetologia58 citations Open access
Semantic Scholar
Elevated serum heparanase‐1 levels in patients with pancreatic carcinoma are associated with poor survival
R. Quiros, G. Rao, J. Plate, J. Harris +5 more
2006Cancer56 citations Open access
Semantic Scholar
STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation.
Etienne Masle-Farquhar, Katherine J. L. Jackson, Timothy J. Peters, Ghamdan Al-Eryani +27 more
2022Immunity52 citations Open access
Semantic Scholar
Activating mutations in PIK3CD and murine CD4+ T cells
Julia Bier, G. Rao, Kathryn J. Payne, Henry Brigden +24 more
2019Journal of Allergy and Clinical Immunology49 citations Open access
Semantic Scholar
Activation of the Sonic Hedgehog pathway in thyroid neoplasms and its potential role in tumor cell proliferation.
Xiulong Xu, H. Ding, G. Rao, Shalini Arora +5 more
2012Endocrine-Related Cancer49 citations Open access
Semantic Scholar
Estradiol induces heparanase-1 expression and heparan sulphate proteoglycan degradation in human endometrium.
Xiulong Xu, Jian-Chi Ding, G. Rao, Jikun Shen +3 more
2007Human Reproduction46 citations
Semantic Scholar
The E3 Ubiquitin Ligases, HUWE1 and NEDD4-1, Are Involved in the Post-translational Regulation of the ABCG1 and ABCG4 Lipid Transporters*
Shereen M. Aleidi, Vicky Howe, Laura J. Sharpe, Alryel Yang +3 more
2015Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β
Juan Li, M. Ritelli, Cindy S. Ma, G. Rao +32 more
2019Science immunology44 citations Open access
Semantic Scholar
Clinicopathological significance of major histocompatibility complex class I-related chain a and B expression in thyroid cancer.
Xiulong Xu, G. Rao, M. Gaffud, H. Ding +8 more
2006Journal of Clinical Endocrinology and Metabolism43 citations
Semantic Scholar
Role of IL-27 in Epstein–Barr virus infection revealed by IL-27RA deficiency
Emmanuel Martin, Sarah Winter, Cécile Garcin, Kay Tanita +28 more
2024Nature39 citations Open access
Semantic Scholar
Cholesterol sensing by the ABCG1 lipid transporter: Requirement of a CRAC motif in the final transmembrane domain.
Laura J. Sharpe, G. Rao, Peter M. S. Jones, Elizabeth Glancey +4 more
2015Biochimica et Biophysica Acta36 citations
Semantic Scholar
Inhibition of p70 S6 Kinase (S6K1) Activity by A77 1726 and Its Effect on Cell Proliferation and Cell Cycle Progress
Michelle E. Doscas, Ashley J. Williamson, L. Usha, Y. Bogachkov +9 more
2014Neoplasia35 citations Open access
Semantic Scholar
Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling
Masato Ogishi, Koji Kitaoka, K. Good-Jacobson, Darawan Rinchai +60 more
2024Immunity34 citations Open access
Semantic Scholar
The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages.
Shereen M. Aleidi, Alryel Yang, Laura J. Sharpe, G. Rao +5 more
2018Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids31 citations
Semantic Scholar
Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents.
R. Lévy, D. Langlais, V. Béziat, Franck Rapaport +43 more
2021Journal of Clinical Investigation27 citations Open access
Semantic Scholar
STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis.
Simon J. Pelham, M. Caldirola, D. Avery, J. Mackie +25 more
2022Journal of Allergy and Clinical Immunology26 citations Open access
Semantic Scholar
Induction of heparanase-1 expression by mutant B-Raf kinase: role of GA binding protein in heparanase-1 promoter activation.
G. Rao, Ding-Xie Liu, M. Xing, Jordi Tauler +2 more
2010Neoplasia24 citations Open access
Semantic Scholar
In Vivo and in Vitro Degradation of Heparan Sulfate (HS) Proteoglycans by HPR1 in Pancreatic Adenocarcinomas
Xiulong Xu, G. Rao, R. Quiros, A. Kim +5 more
2007Journal of Biological Chemistry24 citations Open access
Semantic Scholar
A deep intronic splice mutation of STAT3 underlies hyper IgE syndrome by negative dominance
J. Khourieh, G. Rao, T. Habib, D. Avery +21 more
2019Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
Mesenchymal Stem Cells Develop Tumor Tropism but Do Not Accelerate Breast Cancer Tumorigenesis in a Somatic Mouse Breast Cancer Model
L. Usha, G. Rao, Kent Christopherson Ii, Xiulong Xu
2013PLoS ONE16 citations Open access
Semantic Scholar
Xanthine oxidoreductase is required for genotoxic stress-induced NKG2D ligand expression and gemcitabine-mediated antitumor activity
Xiulong Xu, G. Rao, Yi Li
2016OncoTarget15 citations Open access
Semantic Scholar
Protein kinase A modulates the activity of a major human isoform of ABCG1[S]
I. Gelissen, Laura J. Sharpe, C. Sandoval, G. Rao +4 more
2012Journal of Lipid Research15 citations Open access
Semantic Scholar
Helper T cell immunity in humans with inherited CD4 deficiency
A. Guérin, M. Moncada-Vélez, Katherine J. L. Jackson, Masato Ogishi +49 more
2024Journal of Experimental Medicine12 citations Open access
Semantic Scholar
Phase 2a/b randomised placebo-controlled dose-escalation trial of triheptanoin for ataxia-telangiectasia: treating mitochondrial dysfunction with anaplerosis
Matthew Lynch, Sophie Manoy, Peter D. Sly, C. Wainwright +24 more
2025EBioMedicine9 citations Open access
Semantic Scholar
A Novel Case of IFNAR1 Deficiency Identified a Common Canonical Splice Site Variant in DOCK8 in Western Polynesia: The Importance of Validating Variants of Unknown Significance in Under-Represented Ancestries
Aimee Huynh, Paul E. Gray, Anna Sullivan, J. Mackie +20 more
2024Journal of Clinical Immunology5 citations Open access
Semantic Scholar
Inborn errors of immunity reveal the molecular requirements for the generation and maintenance of human IL-9 expressing cells
G. Rao, Corinne D Mack, Tina Nguyen, Natalie Wong +34 more
2024Journal of Allergy and Clinical Immunology3 citations Open access
Semantic Scholar
Increased expression of MICA in serum of pancreatic cancer patients
K. Weber, G. Rao, R. Quiros, R. Bajnrauh +2 more
20043 citations
Semantic Scholar
STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological dysregulation of NKG2Dhi CD8 killer T cells
Etienne Masle-Farquhar, Katherine J. L. Jackson, Timothy J. Peters, Ghamdan Al-Eryani +26 more
2022bioRxiv2 citations Open access
Semantic Scholar
Monogenic mutations differentially impact the quantity and quality of T follicular helper cells in human primary immunodeficiencies
Cindy S. Ma, Natalie Wong, Hons, G. Rao +60 more
20162 citations
Semantic Scholar
Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis
Diana Olguín Calderón, L. Kilpatrick, C. Conil, Quentin Philippot +86 more
2026Journal of Experimental Medicine1 citations Open access
Semantic Scholar
Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function
Taja Vatovec, Anna-Lena Neehus, Katherine J. L. Jackson, D. Avery +82 more
2026Nature Immunology1 citations Open access
Semantic Scholar
Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis
Diana Olguín Calderón, L. Kilpatrick, C. Conil, Quentin Philippot +86 more
2026bioRxiv1 citations Open access
Semantic Scholar
Impact of novel genetic variants in HYOU1 on neutrophil phenotype
Yoko Mizoguchi, Fumiaki Sakura, Tadashi Anan, Kensaku Kohrogi +14 more
2025Blood1 citations
Semantic Scholar
A Novel STAT3 N-Terminal Domain Variant Reveals an Alternative Mechanism of Disease Pathogenesis in Hyper-IgE Syndrome
J. Mackie, Suan Dan, Danielle Avery, G. Rao +9 more
2026Journal of Human Immunity0 citations Open access
Semantic Scholar
NK cell dysfunction and interferon-γ production underlie autoinflammation in mevalonate kinase deficiency.
Marcia A. Munoz, I. Schuster, James Cremasco, Etienne Masle-Farquhar +31 more
2026Immunity0 citations Open access
Semantic Scholar
Correction to: A Novel Case of IFNAR1 Deficiency Identified a Common Canonical Splice Site Variant in DOCK8 in Western Polynesia: The Importance of Validating Variants of Unknown Significance in Under-Represented Ancestries
Aimee Huynh, Paul E. Gray, Anna Sullivan, J. Mackie +20 more
2024Journal of Clinical Immunology0 citations Open access
Semantic Scholar
P94: THE IMPACT OF COVID‐19 ON PATIENTS WITH PRIMARY AND SECONDARY IMMUNODEFICIENCIES: A STUDY INTO THE PHYSIOLOGICAL, PSYCHOLOGICAL AND SOCIOLOGICAL EFFECTS
F. Perram, P. Burton, Michael D. Smith, C. Yea +9 more
2022Internal medicine journal (Print)0 citations Open access
Semantic Scholar

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