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Maria Laura Pati · SciRah

Researcher profile · Semantic Scholar

Maria Laura Pati

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Maria Laura Pati — researcher profile on SciRah

h-index: 12
Works: 17
Citations: 283

Most-cited papers

Sigma‐2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma‐2 receptor ligands to PGRMC1
Maria Laura Pati, Diana Groza, C. Riganti, J. Kopecka +9 more
2017Pharmacological Research45 citations Open access
Semantic Scholar
Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer
Maria Laura Pati, John R. Hornick, M. Niso, F. Berardi +3 more
2017BMC Cancer39 citations Open access
Semantic Scholar
Multifunctional Thiosemicarbazones and Deconstructed Analogues as a Strategy to Study the Involvement of Metal Chelation, Sigma-2 (σ2) Receptor and P-gp Protein in the Cytotoxic Action: in vitro and in vivo Activity in Pancreatic Tumors
Maria Laura Pati, M. Niso, D. Spitzer, F. Berardi +4 more
2017European journal of medicinal chemistry38 citations Open access
Semantic Scholar
Novel and Selective Fluorescent σ2‐Receptor Ligand with a 3,4‐Dihydroisoquinolin‐1‐one Scaffold: A Tool to Study σ2 Receptors in Living Cells
M. Niso, C. Riganti, Maria Laura Pati, D. Ghigo +2 more
2015ChemBioChem27 citations Open access
Semantic Scholar
Targeting COX-1 by mofezolac-based fluorescent probes for ovarian cancer detection.
A. Scilimati, S. Ferorelli, M. Iaselli, Morena Miciaccia +5 more
2019European journal of medicinal chemistry20 citations
Semantic Scholar
Novel metal chelators thiosemicarbazones with activity at the σ2 receptors and P-glycoprotein: an innovative strategy for resistant tumor treatment
Maria Laura Pati, M. Niso, S. Ferorelli, C. Abate +1 more
201520 citations Open access
Semantic Scholar
Quantum Dot Based Luminescent Nanoprobes for Sigma-2 Receptor Imaging.
Maria Laura Pati, E. Fanizza, Sonja Hager, Diana Groza +7 more
2018Molecular Pharmaceutics16 citations
Semantic Scholar
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability.
Maria Laura Pati, P. Vitale, S. Ferorelli, M. Iaselli +12 more
2019European journal of medicinal chemistry15 citations Open access
Semantic Scholar
Rigid versus flexible anilines or anilides confirm the bicyclic ring as the hydrophobic portion for optimal σ2 receptor binding and provide novel tools for the development of future σ2 receptor PET radiotracers
M. Niso, Maria Laura Pati, F. Berardi, C. Abate
201613 citations
Semantic Scholar
Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate P-glycoprotein (P-gp) activity from σ2 receptor affinity in mixed P-gp/σ2 receptor agents.
Maria Laura Pati, C. Abate, M. Contino, S. Ferorelli +4 more
2015European journal of medicinal chemistry12 citations Open access
Semantic Scholar
Development of sigma-1 (σ1) receptor fluorescent ligands as versatile tools to study σ1 receptors
C. Abate, C. Riganti, Maria Laura Pati, D. Ghigo +4 more
2015European journal of medicinal chemistry12 citations Open access
Semantic Scholar
From mixed sigma-2 receptor/P-glycoprotein targeting agents to selective P-glycoprotein modulators: small structural changes address the mechanism of interaction at the efflux pump.
C. Abate, Maria Laura Pati, M. Contino, N. Colabufo +3 more
2015European journal of medicinal chemistry12 citations Open access
Semantic Scholar
Intelligent Microarray Data Analysis through Non-negative Matrix Factorization to Study Human Multiple Myeloma Cell Lines
Gabriella Casalino, M. Coluccia, Maria Laura Pati, A. Pannunzio +3 more
2019Applied Sciences9 citations Open access
Semantic Scholar
Synthesis, radiolabelling, and evaluation of [11C]PB212 as a radioligand for imaging sigma-1 receptors using PET.
Francesco Spinelli, Ahmed Haider, A. Toscano, Maria Laura Pati +5 more
2018American Journal of Nuclear Medicine and Molecular Imaging4 citations
Semantic Scholar
Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[ 3-( 5-methoxy-1 , 2 , 3 , 4-tetrahydronaphthalen-1-yl ) propyl ] piperazine ( PB 28 ) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer
Maria Laura Pati, John R. Hornick, M. Niso, F. Berardi +3 more
20171 citations
Semantic Scholar
The concomitant effect of anti-MM drugs in combination with COX inhibitors
Maria Laura Pati, A. Scilimati, M. Perrone
20170 citations
Semantic Scholar
The controversial identity of the sigma-2 receptor with PGRMC1: is the PGRMC1/sigma-2 protein, that binds Abeta oligomer, made of two independent molecular entities?
C. Abate, M. Niso, Maria Laura Pati, N. Colabufo +1 more
20150 citations
Semantic Scholar

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