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Ashutosh Kumar · SciRah

Researcher profile · Semantic Scholar

Ashutosh Kumar

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Ashutosh Kumar — researcher profile on SciRah

h-index: 46
Works: 125
Citations: 6,430

Most-cited papers

Oxidative stress and nerve damage: Role in chemotherapy induced peripheral neuropathy
A. Areti, Veera Ganesh Yerra, V. Naidu, Ashutosh Kumar
2014Redox Biology436 citations Open access
Semantic Scholar
Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-κB pathways in diabetic neuropathy
Veera Ganesh Yerra, Geeta Negi, S. Sharma, Ashutosh Kumar
2013Redox Biology393 citations Open access
Semantic Scholar
Neuroinflammation and Oxidative Stress in Diabetic Neuropathy: Futuristic Strategies Based on These Targets
Reddemma Sandireddy, Veera Ganesh Yerra, A. Areti, P. Komirishetty +1 more
2014International Journal of Endocrinology361 citations Open access
Semantic Scholar
Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental nonalcoholic steatohepatitis
S. Chatterjee, Douglas Ganini, Erik J. Tokar, Ashutosh Kumar +6 more
2012Journal of Hepatology143 citations Open access
Semantic Scholar
SNEDDS curcumin formulation leads to enhanced protection from pain and functional deficits associated with diabetic neuropathy: an insight into its mechanism for neuroprotection.
Rayanta P Joshi, Geeta Negi, Ashutosh Kumar, Y. Pawar +3 more
2013Nanomedicine: Nanotechnology, Biology and Medicine135 citations
Semantic Scholar
Melatonin prevents mitochondrial dysfunction and promotes neuroprotection by inducing autophagy during oxaliplatin‐evoked peripheral neuropathy
A. Areti, P. Komirishetty, Manasaveena Akuthota, R. Malik +1 more
2017Journal of Pineal Research129 citations
Semantic Scholar
Fluorescent proteins such as eGFP lead to catalytic oxidative stress in cells
Douglas Ganini, F. Leinisch, Ashutosh Kumar, Jinjie Jiang +4 more
2017Redox Biology113 citations Open access
Semantic Scholar
Isoliquiritigenin reduces oxidative damage and alleviates mitochondrial impairment by SIRT1 activation in experimental diabetic neuropathy.
Veera Ganesh Yerra, A. Kalvala, Ashutosh Kumar
2017Journal of Nutritional Biochemistry108 citations
Semantic Scholar
Targeting AMPK in Diabetes and Diabetic Complications: Energy homeostasis, Autophagy and Mitochondrial health.
Y. Madhavi, N. Gaikwad, Veera Ganesh Yerra, A. Kalvala +2 more
2019Current Medicinal Chemistry106 citations
Semantic Scholar
Biochemical and molecular mechanisms of N-acetyl cysteine and silymarin-mediated protection against maneb- and paraquat-induced hepatotoxicity in rats.
Israr Ahmad, S. Shukla, Ashutosh Kumar, Brajesh K. Singh +5 more
2013Chemico-Biological Interactions102 citations
Semantic Scholar
Inducible nitric oxide synthase is key to peroxynitrite-mediated, LPS-induced protein radical formation in murine microglial BV2 cells
Ashutosh Kumar, Shih-Heng Chen, M. Kadiiska, Jau-Shyong Hong +3 more
2014Free Radical Biology & Medicine93 citations Open access
Semantic Scholar
Fisetin Imparts Neuroprotection in Experimental Diabetic Neuropathy by Modulating Nrf2 and NF-κB Pathways
Reddemma Sandireddy, Veera Ganesh Yerra, Prashanth Komirishetti, A. Areti +1 more
2016Cellular and molecular neurobiology90 citations Open access
Semantic Scholar
Morin exerts neuroprotection via attenuation of ROS induced oxidative damage and neuroinflammation in experimental diabetic neuropathy
Pragna Bachewal, Chayanika Gundu, Veera Ganesh Yerra, A. Kalvala +2 more
2018Biofactors84 citations
Semantic Scholar
Adenosine Monophosphate-Activated Protein Kinase Abates Hyperglycaemia-Induced Neuronal Injury in Experimental Models of Diabetic Neuropathy: Effects on Mitochondrial Biogenesis, Autophagy and Neuroinflammation
Veera Ganesh Yerra, Ashutosh Kumar
2016Molecular Neurobiology84 citations
Semantic Scholar
Adenosine monophosphate‐activated protein kinase modulation by berberine attenuates mitochondrial deficits and redox imbalance in experimental diabetic neuropathy
Veera Ganesh Yerra, A. Kalvala, Bhoomika Sherkhane, A. Areti +1 more
2018Neuropharmacology74 citations
Semantic Scholar
Oxidative Stress and Inflammation in Diabetic Complications
Ajit Vikram, D. Tripathi, Ashutosh Kumar, S. Singh
2014International Journal of Endocrinology74 citations Open access
Semantic Scholar
SIRT1 Activation by Polydatin Alleviates Oxidative Damage and Elevates Mitochondrial Biogenesis in Experimental Diabetic Neuropathy
Preethi Bheereddy, Veera Ganesh Yerra, A. Kalvala, Bhoomika Sherkhane +1 more
2020Cellular and molecular neurobiology71 citations
Semantic Scholar
Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice.
R. Seth, Ashutosh Kumar, Suvarthi Das, M. Kadiiska +3 more
2013Toxicological Sciences69 citations Open access
Semantic Scholar
Involvement of NADPH oxidase and glutathione in zinc-induced dopaminergic neurodegeneration in rats: similarity with paraquat neurotoxicity.
Ashutosh Kumar, Brajesh K. Singh, Israr Ahmad, S. Shukla +5 more
2012Brain Research69 citations
Semantic Scholar
Rosmarinic Acid Mitigates Mitochondrial Dysfunction and Spinal Glial Activation in Oxaliplatin-induced Peripheral Neuropathy
A. Areti, P. Komirishetty, A. Kalvala, Karthika Nellaiappan +1 more
2018Molecular Neurobiology66 citations
Semantic Scholar
Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis.
Suvarthi Das, R. Seth, Ashutosh Kumar, M. Kadiiska +3 more
2013American Journal of Physiology - Gastrointestinal and Liver Physiology63 citations Open access
Semantic Scholar
Role of cytochrome c in α-synuclein radical formation: implications of α-synuclein in neuronal death in Maneb- and paraquat-induced model of Parkinson’s disease
Ashutosh Kumar, Douglas Ganini, R. Mason
2016Molecular Neurodegeneration61 citations Open access
Semantic Scholar
Morin Mitigates Chronic Constriction Injury (CCI)-Induced Peripheral Neuropathy by Inhibiting Oxidative Stress Induced PARP Over-Activation and Neuroinflammation
P. Komirishetty, A. Areti, R. Sistla, Ashutosh Kumar
2016Neurochemical Research59 citations
Semantic Scholar
PARP inhibition attenuates neuroinflammation and oxidative stress in chronic constriction injury induced peripheral neuropathy.
P. Komirishetty, A. Areti, Veera Ganesh Yerra, Ruby Pk +4 more
2016Life Science59 citations
Semantic Scholar
Formation and implications of alpha-synuclein radical in Maneb- and paraquat-induced models of Parkinson’s disease
Ashutosh Kumar, F. Leinisch, M. Kadiiska, J. Corbett +1 more
2015Molecular Neurobiology56 citations Open access
Semantic Scholar
Neuroprotection by resveratrol in diabetic neuropathy: concepts & mechanisms.
Ashutosh Kumar, Geeta Negi, Shyam S. Sharma
2013Current Medicinal Chemistry50 citations
Semantic Scholar
Bardoxolone Methyl Ameliorates Hyperglycemia Induced Mitochondrial Dysfunction by Activating the keap1-Nrf2-ARE Pathway in Experimental Diabetic Neuropathy
A. Kalvala, Rahul Kumar, Bhoomika Sherkhane, Chayanika Gundu +2 more
2020Molecular Neurobiology49 citations
Semantic Scholar
Potential Therapeutic Benefits of Maintaining Mitochondrial Health in Peripheral Neuropathies
A. Areti, Veera Ganesh Yerra, P. Komirishetty, Ashutosh Kumar
2016Current Neuropharmacology49 citations Open access
Semantic Scholar
Nrf2 and NF-κB modulation by Plumbagin attenuates functional, behavioural and biochemical deficits in rat model of neuropathic pain
V. Arruri, P. Komirishetty, A. Areti, Siva Kumar Naik Dungavath +1 more
2017Pharmacological Reports48 citations
Semantic Scholar
Combination strategy of PARP inhibitor with antioxidant prevent bioenergetic deficits and inflammatory changes in CCI‐induced neuropathy
P. Komirishetty, A. Areti, R. Gogoi, R. Sistla +1 more
2017Neuropharmacology44 citations
Semantic Scholar
Carvedilol prevents functional deficits in peripheral nerve mitochondria of rats with oxaliplatin‐evoked painful peripheral neuropathy
A. Areti, P. Komirishetty, Ashutosh Kumar
2017Toxicology and Applied Pharmacology43 citations
Semantic Scholar
Autophagy and Mitochondria: Targets in Neurodegenerative Disorders.
Ashutosh Kumar, A. Dhawan, Alknanda Kadam, Akshada Shinde
2018CNS and Neurological Disorders - Drug Targets42 citations
Semantic Scholar
Probucol attenuates NF-κB/NLRP3 signalling and augments Nrf-2 mediated antioxidant defence in nerve injury induced neuropathic pain.
Kalyani Derangula, Mohit Javalgekar, Vijay Kumar Arruri, Chayanika Gundu +2 more
2021International Immunopharmacology39 citations
Semantic Scholar
CYP2E1-Dependent and Leptin-Mediated Hepatic CD57 Expression on CD8+ve T Cells aid Progression of Environment-Linked Nonalcoholic Steatohepatitis
R. Seth, Suvarthi Das, Ashutosh Kumar, Anindya Chanda +5 more
2013Toxicology and Applied Pharmacology38 citations Open access
Semantic Scholar
Melatonin prevents diabetes‐induced nephropathy by modulating the AMPK/SIRT1 axis: Focus on autophagy and mitochondrial dysfunction
Jain Siddhi, Bhoomika Sherkhane, Anil Kumar Kalavala, V. Arruri +2 more
2022Cell Biology International37 citations
Semantic Scholar
Mitochondrial Dysfunction is a Crucial Immune Checkpoint for Neuroinflammation and Neurodegeneration: mtDAMPs in Focus
Y. Mishra, Ashutosh Kumar, Ravinder K. Kaundal
2024Molecular Neurobiology36 citations
Semantic Scholar
Curcumin: a pleiotropic phytonutrient in diabetic complications.
Manish Kumar Jeenger, S. Shrivastava, Veera Ganesh Yerra, V. Naidu +2 more
2015Nutrition (Burbank, Los Angeles County, Calif.)36 citations
Semantic Scholar
Boswellia ovalifoliolata abrogates ROS mediated NF-κB activation, causes apoptosis and chemosensitization in Triple Negative Breast Cancer cells.
Dinesh Thummuri, M. Jeengar, S. Shrivastava, A. Areti +6 more
2014Environmental Toxicology and Pharmacology35 citations
Semantic Scholar
Proinflammatory Adipokine Leptin Mediates Disinfection Byproduct Bromodichloromethane-induced Early Steatohepatitic Injury in Obesity
Suvarthi Das, Ashutosh Kumar, R. Seth, Erik J. Tokar +4 more
2013Toxicology and Applied Pharmacology35 citations Open access
Semantic Scholar
Chronic Endurance Exercise Impairs Cardiac Structure and Function in Middle-Aged Mice with Impaired Nrf2 Signaling
Gobinath Shanmugam, M. Narasimhan, Robbie L. Conley, T. Sairam +5 more
2017Frontiers in Physiology33 citations Open access
Semantic Scholar
Oxidative Stress and Autophagy in Metabolism and Longevity
Ajit Vikram, R. Anish, Ashutosh Kumar, D. Tripathi +1 more
2017Oxidative Medicine and Cellular Longevity30 citations Open access
Semantic Scholar
Autophagy: The missing link in diabetic neuropathy?
Veera Ganesh Yerra, Chayanika Gundu, Pragna Bachewal, Ashutosh Kumar
2016Medical Hypotheses30 citations
Semantic Scholar
Chronic hyperglycemia impairs mitochondrial unfolded protein response and precipitates proteotoxicity in experimental diabetic neuropathy: focus on LonP1 mediated mitochondrial regulation
A. Kalvala, Veera Ganesh Yerra, Bhoomika Sherkhane, Chayanika Gundu +3 more
2020Pharmacological Reports27 citations
Semantic Scholar
Mitochondrial dysfunction in diabetic neuropathy: Impaired mitophagy triggers NLRP3 inflammasome.
Keshari Sriwastawa, Ashutosh Kumar
2024Mitochondrion (Amsterdam. Print)26 citations
Semantic Scholar
Sulfite-induced protein radical formation in LPS aerosol-challenged mice: Implications for sulfite sensitivity in human lung disease
Ashutosh Kumar, M. Triquigneaux, J. Madenspacher, K. Ranguelova +3 more
2017Redox Biology24 citations Open access
Semantic Scholar
Nitric Oxide Down-Regulates Topoisomerase I and Induces Camptothecin Resistance in Human Breast MCF-7 Tumor Cells
Nilesh Kumar Sharma, Ashutosh Kumar, Amrita Kumari, Erik J. Tokar +6 more
2015PLoS ONE24 citations Open access
Semantic Scholar
Dynamin-Independent Mechanisms of Endocytosis and Receptor Trafficking
Chayanika Gundu, V. Arruri, Poonam Yadav, Umashanker Navik +4 more
2022Cells23 citations Open access
Semantic Scholar
Neuroprotective Effect of Baicalein Against Oxaliplatin-Induced Peripheral Neuropathy: Impact on Oxidative Stress, Neuro-inflammation and WNT/β-Catenin Signaling
Simrandeep Jugait, A. Areti, Karthika Nellaiappan, Priyanka Narwani +3 more
2022Molecular Neurobiology23 citations Open access
Semantic Scholar
LONP1 induction by SRT1720 attenuates mitochondrial dysfunction against high glucose induced neurotoxicity in PC12 cells.
A. Kalvala, Veera Ganesh Yerra, Ashutosh Kumar
2020Toxicology in Vitro23 citations
Semantic Scholar
Nrf2: a promising trove for diabetic wound healing.
Amruta Jindam, Veera Ganesh Yerra, Ashutosh Kumar
2017Annals of Translational Medicine23 citations Open access
Semantic Scholar

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Veera Ganesh Yerra — researcher profile on SciRah
A. Areti×15
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M. Kadiiska — researcher profile on SciRah

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Chayanika Gundu×6

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S. Chatterjee×5

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Suvarthi Das×5

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Bhoomika Sherkhane×5

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