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J. Madenspacher · SciRah

Researcher profile · Semantic Scholar

J. Madenspacher

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J. Madenspacher — researcher profile on SciRah

h-index: 22
Works: 60
Citations: 1,501

Most-cited papers

APOε 4 is associated with enhanced in vivo innate immune responses in humans
Stephen C. Gale, Li Gao, C. Mikacenic, S. Coyle +15 more
2014Journal of Allergy and Clinical Immunology193 citations Open access
Semantic Scholar
A pneumocyte-macrophage paracrine lipid axis drives the lung toward fibrosis.
Freddy Romero, Dilip Shah, Michelle Duong, R. Penn +8 more
2014American Journal of Respiratory Cell and Molecular Biology164 citations Open access
Semantic Scholar
IRGM1 links mitochondrial quality control to autoimmunity
P. Rai, K. Janardhan, Julie M. Meacham, J. Madenspacher +10 more
2021Nature Immunology123 citations Open access
Semantic Scholar
Effects of Liver X Receptor Agonist Treatment on Pulmonary Inflammation and Host Defense1
Kathleen A. Smoak, J. Madenspacher, S. Jeyaseelan, Belinda Williams +5 more
2008Journal of Immunology89 citations Open access
Semantic Scholar
Novel Relationship of Serum Cholesterol with Asthma and Wheeze in the United States
M. Fessler, M. Massing, B. Spruell, R. Jaramillo +5 more
2009Journal of Allergy and Clinical Immunology77 citations Open access
Semantic Scholar
Myeloid Differentiation Primary Response Protein 88 Couples Reverse Cholesterol Transport to Inflammation
Kathleen A. Smoak, J. Aloor, J. Madenspacher, B. Merrick +6 more
2010Cell Metabolism72 citations Open access
Semantic Scholar
Combined Therapy of Dietary Fish Oil and Stearoyl-CoA Desaturase 1 (SCD1) Inhibition Prevents The Metabolic Syndrome and Atherosclerosis
J. Brown, Soonkyu Chung, J. Sawyer, C. Degirolamo +14 more
2009Arteriosclerosis, Thrombosis and Vascular Biology67 citations Open access
Semantic Scholar
Cholesterol-25-hydroxylase promotes efferocytosis and resolution of lung inflammation.
J. Madenspacher, E. Morrell, K. Gowdy, J. McDonald +15 more
2020JCI Insight65 citations Open access
Semantic Scholar
MicroRNA-33 Regulates the Innate Immune Response via ATP Binding Cassette Transporter-mediated Remodeling of Membrane Microdomains *
Li-Hua Lai, Kathleen M. Azzam, Wan-Chi Lin, P. Rai +7 more
2016Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Alterations in the Rat Serum Proteome during Liver Injury from Acetaminophen Exposure
B. Merrick, M. Bruno, J. Madenspacher, B. Wetmore +8 more
2006Journal of Pharmacology and Experimental Therapeutics57 citations Open access
Semantic Scholar
CGI-58/ABHD5-Derived Signaling Lipids Regulate Systemic Inflammation and Insulin Action
C. Lord, Jenna L. Betters, P. Ivanová, S. Milne +14 more
2012Diabetes50 citations Open access
Semantic Scholar
Dyslipidemia Induces Opposing Effects on Intrapulmonary and Extrapulmonary Host Defense through Divergent TLR Response Phenotypes
J. Madenspacher, D. Draper, Kathleen A. Smoak, Haitao Li +5 more
2010Journal of Immunology47 citations Open access
Semantic Scholar
Apolipoproteins and Apolipoprotein Mimetic Peptides Modulate Phagocyte Trafficking through Chemotactic Activity*
J. Madenspacher, Kathleen M. Azzam, W. Gong, K. Gowdy +5 more
2012Journal of Biological Chemistry42 citations Open access
Semantic Scholar
ATP-binding cassette transporter G1 deficiency dysregulates host defense in the lung.
D. Draper, J. Madenspacher, D. Dixon, Debra King +2 more
2010American Journal of Respiratory and Critical Care Medicine39 citations Open access
Semantic Scholar
Apolipoprotein E-Deficient Mice Are Susceptible to the Development of Acute Lung Injury
C. Yamashita, M. Fessler, L. Vasanthamohan, J. Lac +8 more
2014Respiration36 citations Open access
Semantic Scholar
Complementary gene and protein expression studies and integrative approaches in toxicogenomics.
B. Merrick, J. Madenspacher
2005Toxicology and Applied Pharmacology35 citations
Semantic Scholar
ATP Binding Cassette Transporter G1 Deletion Induces IL-17-dependent Dysregulation of Pulmonary Adaptive Immunity
D. Draper, K. Gowdy, J. Madenspacher, Rhonda H. Wilson +7 more
2012Journal of Immunology33 citations Open access
Semantic Scholar
Chemical effects in biological systems--data dictionary (CEBS-DD): a compendium of terms for the capture and integration of biological study design description, conventional phenotypes, and 'omics data.
J. Fostel, Danielle Choi, C. Zwickl, N. Morrison +25 more
2005Toxicological Sciences33 citations
Semantic Scholar
Epithelial membrane protein 2 governs transepithelial migration of neutrophils into the airspace.
Wan-Chi Lin, K. Gowdy, J. Madenspacher, R. Zemans +8 more
2019Journal of Clinical Investigation27 citations Open access
Semantic Scholar
Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.
Kathleen M. Azzam, J. Madenspacher, D. Cain, Li-Hua Lai +10 more
2017JCI Insight26 citations Open access
Semantic Scholar
Key Role for Scavenger Receptor B-I in the Integrative Physiology of Host Defense during Bacterial Pneumonia
K. Gowdy, J. Madenspacher, Kathleen M. Azzam, K. Gabor +3 more
2014Mucosal Immunology26 citations Open access
Semantic Scholar
Sulfite-induced protein radical formation in LPS aerosol-challenged mice: Implications for sulfite sensitivity in human lung disease
Ashutosh Kumar, M. Triquigneaux, J. Madenspacher, K. Ranguelova +3 more
2017Redox Biology24 citations Open access
Semantic Scholar
25-Hydroxycholesterol exacerbates vascular leak during acute lung injury
J. Madenspacher, E. Morrell, J. McDonald, Bonne M. Thompson +11 more
2023JCI Insight18 citations Open access
Semantic Scholar
Effects of Orally Ingested Arsenic on Respiratory Epithelial Permeability to Bacteria and Small Molecules in Mice
Michael W. Henderson, J. Madenspacher, G. Whitehead, Seddon Y. Thomas +3 more
2017Environmental Health Perspectives16 citations Open access
Semantic Scholar
In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
M. Hodge, S. Reece, J. Madenspacher, K. Gowdy
2019Journal of Visualized Experiments14 citations Open access
Semantic Scholar
Myeloid atg5 deletion impairs n-3 PUFA-mediated atheroprotection
Zhan Wang, Russel C. Sequeira, M. Zabalawi, J. Madenspacher +7 more
2020Atherosclerosis13 citations Open access
Semantic Scholar
Scavenger Receptor BI Attenuates IL-17A-dependent Neutrophilic Inflammation in Asthma.
S. Reece, Sanjay Varikuti, B. Kilburg‐Basnyat, K. Dunigan-Russell +9 more
2021American Journal of Respiratory Cell and Molecular Biology11 citations Open access
Semantic Scholar
Endogenous and Therapeutic 25-Hydroxycholesterols May Worsen Early SARS-CoV-2 Pathogenesis in Mice
M. Fessler, J. Madenspacher, Paul J. Baker, K. Hilligan +11 more
2023American Journal of Respiratory Cell and Molecular Biology9 citations Open access
Semantic Scholar
Sterol biosynthesis regulates TLR signaling and the innate immune response in a Smith-Lemli-Opitz syndrome model
K. Gabor, Emily V Mesev, J. Madenspacher, Julie M. Meacham +9 more
2024Journal of Clinical Investigation7 citations Open access
Semantic Scholar
A Non-invasive and Technically Non-intensive Method for Induction and Phenotyping of Experimental Bacterial Pneumonia in Mice.
J. Madenspacher, M. Fessler
2016Journal of Visualized Experiments7 citations Open access
Semantic Scholar
Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma
E. Lee, W. Choi, A. Burkholder, L. Perera +14 more
2023Frontiers in Genetics5 citations Open access
Semantic Scholar
Hematopoietic Cell-Specific SLC37A2 Deficiency Accelerates Atherosclerosis in LDL Receptor-Deficient Mice
Qing-Xia Zhao, Zhan Wang, Allison K Meyers, J. Madenspacher +9 more
2021Frontiers in Cardiovascular Medicine5 citations Open access
Semantic Scholar
Cholestenoic Acid is a Prognostic Biomarker in Acute Respiratory Distress Syndrome
J. Madenspacher, R. Stapleton, B. Suratt, A. Dixon +9 more
2018Journal of Allergy and Clinical Immunology3 citations Open access
Semantic Scholar
Personalized Environment and Genes Study (PEGS) Dataset-a resource for genomic, exposomic, and geospatial data
F. Akhtari, J. Madenspacher, D. D'Agostin, Samantha Shuptrine +13 more
2026Scientific Data1 citations Open access
Semantic Scholar
Race-specific association of an IRGM risk allele with cytokine expression in human subjects
T. Ajayi, P. Rai, Min Shi, K. Gabor +6 more
2023Scientific Reports1 citations Open access
Semantic Scholar
Evaluation of endogenous and therapeutic 25-hydroxycholesterols in murine models of pulmonary SARS-CoV-2 infection
M. Fessler, J. Madenspacher, Paul J. Baker, K. Hilligan +9 more
2022bioRxiv1 citations Open access
Semantic Scholar
MicroRNA-33 Regulates Inflammation and Fibrosis in the Injured Lung
F. Zhao, J. Madenspacher, Wan-Ching Lin, M. Fessler
2019A60. LUNG INJURY, SEPSIS, AND ARDS1 citations
Semantic Scholar
Scavenger receptor class B type I (SR-BI) modulates glucocorticoid mediated lymphocyte apoptosis in asthma
S. Reece, B. Kilburg‐Basnyat, J. Madenspacher, Bin Luo +3 more
2017Journal of Immunology1 citations
Semantic Scholar
Smith-Lemli-Opitz syndrome reveals requirement for sterol biosynthesis in the innate immune response
K. Gabor, J. Madenspacher, C. Wassif, P. Bushel +2 more
2016Journal of Immunology1 citations
Semantic Scholar
Leucine rich repeats and calponin homology containing protein 4 (Lrch4) is a novel regulator of Toll-like receptor signaling (68.8)
J. Aloor, K. Gowdy, Kathleen M. Azzam, J. Madenspacher +5 more
2012Journal of Immunology1 citations
Semantic Scholar
ATP Binding Cassette Transporter G1 Is a Negative Regulator of Pulmonary Innate Immunity.
D. Draper, J. Madenspacher, L. DeGraff, M. Fessler
2009Asian Test Symposium1 citations
Semantic Scholar
Hematopoietic-SLC37A2 deficiency impairs M2 macrophage polarization and accelerates atherosclerosis in LDL receptor-deficient mice
Qing-Xia Zhao, Zhan Wang, Allison K Meyers, J. Madenspacher +10 more
20210 citations
Semantic Scholar
Hematopoietic-SLC37A2 deficiency accelerates atherosclerosis in LDL receptor-deficient mice
Qinghua Zhao, Zhan Wang, Allison K Meyers, J. Madenspacher +8 more
2021bioRxiv0 citations Open access
Semantic Scholar
The Role of Epithelial Membrane Protein 2 in Regulation of Pulmonary Fibrosis and Tissue Remodeling
Wan-Chi Lin, J. Madenspacher, Carmen J. Williams, M. Fessler
20200 citations
Semantic Scholar
Epithelial membrane protein 2 regulates transepithelial migration of neutrophils into the inflamed airspace
Wan-Chi Lin, K. Gowdy, J. Madenspacher, R. Zemans +8 more
2019Journal of Immunology0 citations
Semantic Scholar
Alveolar Macrophage Expression of Cholesterol 25 Hydroxylase Is Associated with Increased Inflammation and Lung Injury in ARDS
E. Morrell, J. Madenspacher, R. Stapleton, C. Mikacenic +2 more
2019D11. ALL CELLS ON DECK: IMMUNE CELLS AND THE PATHOGENESIS OF LUNG INJURY0 citations
Semantic Scholar
Novel role for scavenger receptor B-I in neutrophilic asthma (IRC10P.419)
K. Gowdy, J. Madenspacher, Seddon Y. Thomas, H. Nakano +2 more
2015Journal of Immunology0 citations
Semantic Scholar
A novel role for Irgm1 in immune homeostasis (MUC1P.906)
Kathleen M. Azzam, J. Madenspacher, Li-Hua Lai, Kimberly Gowdy +6 more
2015Journal of Immunology0 citations
Semantic Scholar
Irgm1 regulates the pulmonary innate immune response (MUC5P.864)
Kathleen M. Azzam, J. Madenspacher, Li-Hua Lai, K. Gowdy +5 more
2014Journal of Immunology0 citations
Semantic Scholar
Leucine rich repeats and calponin homology containing protein 4 (Lrch4) is a novel regulator of Toll-like receptor signaling
J. Aloor, K. Gowdy, Kathleen M. Azzam, J. Madenspacher +5 more
20120 citations
Semantic Scholar

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