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B. Rosenwirth · SciRah

Researcher profile · Semantic Scholar

B. Rosenwirth

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B. Rosenwirth — researcher profile on SciRah

h-index: 20
Works: 62
Citations: 1,646

Most-cited papers

The non‐immunosuppressive cyclosporin DEBIO‐025 is a potent inhibitor of hepatitis C virus replication in vitro
J. Paeshuyse, A. Kaul, E. De Clercq, B. Rosenwirth +4 more
2006Hepatology286 citations Open access
Semantic Scholar
A Pathogenic Threshold of Virus Load Defined in Simian Immunodeficiency Virus- or Simian-Human Immunodeficiency Virus-Infected Macaques
P. T. ten Haaft, B. Verstrepen, K. Überla, B. Rosenwirth +1 more
1998Journal of Virology175 citations Open access
Semantic Scholar
Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus (HIV) type 1: interference with HIV protein-cyclophilin A interactions
A. Billich, F. Hammerschmid, P. Peichl, R. Wenger +3 more
1995Journal of Virology170 citations Open access
Semantic Scholar
Inhibition of Human Immunodeficiency Virus Type 1 Replication in Human Cells by Debio-025, a Novel Cyclophilin Binding Agent
R. Ptak, P. Gallay, Dirk Jochmans, A. Halestrap +11 more
2008Antimicrobial Agents and Chemotherapy110 citations Open access
Semantic Scholar
Old Rhesus Macaques Treated with Interleukin-7 Show Increased TREC Levels And Respond Well to Influenza Vaccination
R. Aspinall, J. Pido‐Lopez, N. Imami, S. Henson +6 more
2007Rejuvenation Research89 citations
Semantic Scholar
Naturally Occurring Capsid Substitutions Render HIV-1 Cyclophilin A Independent in Human Cells and TRIM-cyclophilin-resistant in Owl Monkey Cells*
U. Chatterji, M. Bobardt, R. Stanfield, R. Ptak +9 more
2005Journal of Biological Chemistry81 citations Open access
Semantic Scholar
Herpesvirus Saimiri vFLIP Provides an Antiapoptotic Function but Is Not Essential for Viral Replication, Transformation, or Pathogenicity
Diana Glykofrydes, H. Niphuis, E. Kuhn, B. Rosenwirth +6 more
2000Journal of Virology57 citations Open access
Semantic Scholar
Purification and partial characterization of poliovirus protease 2A by means of a functional assay
H. König, B. Rosenwirth
1988Journal of Virology56 citations Open access
Semantic Scholar
In vitro activity of inhibitors of late stages of the replication of HIV in chronically infected macrophages
C. Perno, S. Aquaro, B. Rosenwirth, E. Balestra +4 more
1994Journal of Leukocyte Biology48 citations Open access
Semantic Scholar
Adenovirus-infected, cell-specific, DNA-binding proteins.
A. J. Levine, P. C. van der Vliet, B. Rosenwirth, J. Rabek +2 more
1975Cold Spring Harbor Symposia on Quantitative Biology48 citations
Semantic Scholar
IgG isotype distribution of local and systemic immune responses induced by influenza virus infection
G. Fazekas, B. Rosenwirth, P. Dukor, J. Gergely +1 more
1994European Journal of Immunology46 citations
Semantic Scholar
The Interleukin-17 Gene of Herpesvirus Saimiri
A. Knappe, C. Hiller, H. Niphuis, F. Fossiez +9 more
1998Journal of Virology45 citations Open access
Semantic Scholar
Antiretroviral Therapy during Primary Immunodeficiency Virus Infection Can Induce Persistent Suppression of Virus Load and Protection from Heterologous Challenge in Rhesus Macaques
B. Rosenwirth, P. T. ten Haaft, W. Bogers, I. Nieuwenhuis +5 more
2000Journal of Virology44 citations Open access
Semantic Scholar
Inhibitors of HIV-1 proteinase containing 2-heterosubstituted 4-amino-3-hydroxy-5-phenylpentanoic acid: synthesis, enzyme inhibition, and antiviral activity.
D. Scholz, A. Billich, B. Charpiot, P. Ettmayer +4 more
1994Journal of Medicinal Chemistry35 citations Open access
Semantic Scholar
[Melle4]Cyclosporin, a Novel Natural Cyclosporin with anti-HIV Activity: Structural Elucidation, Biosynthesis and Biological Properties
R. Traber, H. Kobel, H. Loosli, H. Senn +2 more
199433 citations
Semantic Scholar
Immunostimulatory, but not antiendotoxin, activity of lipid X is due to small amounts of contaminating N,O-acylated disaccharide-1-phosphate: in vitro and in vivo reevaluation of the biological activity of synthetic lipid X
C. Lam, J. Hildebrandt, E. Schütze, B. Rosenwirth +3 more
1991Infection and Immunity30 citations Open access
Semantic Scholar
HIV-1 Integrase: High-Level Production and Screening Assay for the Endonucleolytic Activity
A. Billich, M. Schauer, S. Frank, B. Rosenwirth +1 more
199226 citations
Semantic Scholar
Independence of Herpesvirus-Induced T Cell Lymphoma from Viral Cyclin D Homologue
A. Ensser, Diana Glykofrydes, H. Niphuis, Eva M. Kuhn +5 more
2001Journal of Experimental Medicine25 citations Open access
Semantic Scholar
T-Cell Lymphoma Caused by Herpesvirus Saimiri C488 Independently of ie14/vsag, a Viral Gene with Superantigen Homology
A. Knappe, M. Thurau, H. Niphuis, Christian Hiller +6 more
1998Journal of Virology24 citations Open access
Semantic Scholar
Paracyclophanes: a novel class of water-soluble inhibitors of HIV proteinase.
P. Ettmayer, A. Billich, Peter Hecht, B. Rosenwirth +1 more
1996Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
Debio-025 inhibits HIV-1 by interfering with an early event in the replication cycle.
D. Daelemans, J. Dumont, B. Rosenwirth, E. De Clercq +1 more
2010Antiviral Research19 citations
Semantic Scholar
Structure and replication of echovirus type 12. 1. Analysis of the polypeptides and RNA of echovirus 12 particles.
B. Rosenwirth, H. Eggers
1978European Journal of Biochemistry18 citations
Semantic Scholar
A vaccine strategy utilizing a combination of three different chimeric vectors which share specific vaccine antigens
J. Heeney, G. Koopman, B. Rosenwirth, W. Bogers +11 more
2000Journal of medical primatology17 citations
Semantic Scholar
Correlation of Naturally Occurring HIV-1 Resistance to DEB025 with Capsid Amino Acid Polymorphisms
P. Gallay, R. Ptak, M. Bobardt, J. Dumont +2 more
2013Viruses16 citations Open access
Semantic Scholar
Therapeutic immunization with Modified Vaccinia Virus Ankara (MVA) vaccines in SIV‐infected rhesus monkeys undergoing antiretroviral therapy
K. Überla, B. Rosenwirth, P. T. ten Haaft, J. Heeney +2 more
2007Journal of medical primatology13 citations
Semantic Scholar
The cyclophilin inhibitor Debio-025 is a potent inhibitor of hepatitis C virus replication in vitro with a unique resistance profile
Lotte Coelmont, J. Paeshuyse, Suzanne J. F. Kaptein, I. Vliegen +8 more
200612 citations
Semantic Scholar
In vivo efficacy of SDZ 35-682, a new picornavirus capsid-binding agent.
B. Rosenwirth, Z. Kis, Hans J. Eggers
1995Antiviral Research11 citations
Semantic Scholar
Synthesis and antiviral activity of thiosemicarbazone derivatives of pyridazinecarbaldehydes and alkyl pyridazinyl ketones.
J. Easmon, G. Heinisch, W. Holzer, B. Rosenwirth
1989Arzneimittel-Forschung10 citations
Semantic Scholar
Echovirus 12-induced host cell shutoff is prevented by rhodanine
B. Rosenwirth, H. Eggers
1977Nature10 citations
Semantic Scholar
Herpesvirus saimiri infection of rhesus macaques: A model for acute rhadinovirus‐induced t‐cell transformation and oncogenesis
B. Rosenwirth, I. Kondova, H. Niphuis, Edward J. D. Greenwood +7 more
2011Journal of Medical Virology7 citations
Semantic Scholar
Readily acquired secondary infections of human and simian immunodeficiency viruses following single intravenous exposure in non-human primates.
P. T. ten Haaft, E. Verschoor, B. Verstrepen, H. Niphuis +5 more
2004Journal of General Virology7 citations Open access
Semantic Scholar
Potent and Orally Bioavailable HIV-1 Proteinase Inhibitors Containing the 2-aminobenzylstatine Moiety
A. Billich, D. Scholz, B. Charpiot, H. Gstach +3 more
19956 citations
Semantic Scholar
Mode of action of SDZ NIM 811, a non-immunosuppressive Cyclosporin A analog with activity against human immunodeficiency virus type 1 (HIV-1)
B. Rosenwirth, A. Billich, A. Steinkasserer, F. Hammerschmid +1 more
19956 citations
Semantic Scholar
Assay Systems for HIV-1 Proteinase and Their Use for Evaluation of Inhibitors
A. Billich, S. Billich, B. Rosenwirth
19916 citations Open access
Semantic Scholar
Characteristics of a Pathogenic Molecular Clone of an End-Stage Serum-Derived Variant of Simian Immunodeficiency Virus (SIVF359)
L. Holterman, R. Dubbes, J. Mullins, G. Learn +8 more
2001Journal of Virology5 citations Open access
Semantic Scholar
Kinetics and Isotype Profile of Rheumatoid Factor Production During Viral Infection: Organ Distribution of Antibody Secreting Cells
G. Fazekas, B. Rosenwirth, P. Dukor, J. Gergely +1 more
1996Scandinavian Journal of Immunology5 citations
Semantic Scholar
Measurement of HIV‐1 Reverse Transcriptase by a Nonradioactive Assay System
F. Hammerschmid, E. Maier, B. Rosenwirth
1992Annals of the New York Academy of Sciences5 citations
Semantic Scholar
Interactions of HIV‐1 Proteins with Human T‐Cell Cyclophilin A
F. Hammerschmid, A. Billich, E. Wasserbauer, B. Rosenwirth
1996Annals of the New York Academy of Sciences4 citations
Semantic Scholar
Characterization of an adenovirus early protein required for viral DNA replication: A single strand specific DNA binding protein
A. J. Levine, P. C. van der Vliet, B. Rosenwirth, Carlw Anderson +3 more
1976Molecular and Cellular Biochemistry4 citations
Semantic Scholar
Primate Lentiviruses and AIDS Research
L. Holterman, E. Verschoor, B. Rosenwirth, J. Heeney
19983 citations
Semantic Scholar
Measurement of HIV-1 reverse transcriptase by a nonradioactive assay system.
F. Hammerschmid, E. Maier, B. Rosenwirth
19923 citations
Semantic Scholar
Paracyclophanes: A Novel Class of Water‐Soluble Inhibitors of HIV Proteinase.
P. Ettmayer, A. Billich, Peter Hecht, B. Rosenwirth +1 more
19962 citations
Semantic Scholar
Studies on the mechanism of antiviral action of 5-(2-chloroethyl)-2'-deoxyuridine against herpes-simplex virus
R. Bernaerts, P. Sterkens, P. Herdewijn, B. Rosenwirth +1 more
19882 citations
Semantic Scholar
Synthesis and Antiviral Activity of 5′-O- and 3-N-Substituted Derivatives of 5-(2-Chloroethyl)-2′-deoxyuridine.
H. Griengl, W. Schwarz, F. Schatz, M. Skrobal +2 more
19862 citations
Semantic Scholar
[Thiophene as a structural element of physiologically active substances. 12. Thiophene analogs of antiviral chalcones].
D. Binder, C. Noe, Wolfgang Holzer, B. Rosenwirth
1985Archiv der Pharmazie2 citations
Semantic Scholar
Debio-025, a novel non-immunosuppressive cyclosporine analog with potent anti-human immunodeficiency virus type I activity: Pharmacological properties and mode of action
B. Rosenwirth, M. de Béthune, R. Ptak, L. Pallansch +11 more
20051 citations
Semantic Scholar
21 New highly potent HIV-1 protease inhibitors
D. Scholz, H. Retscher, B. Charpiot, H. Gstach +3 more
19931 citations
Semantic Scholar
2′‐Fluorinated Arabinonucleosides of 5‐(2‐Haloalkyl)uracil: Synthesis and Antiviral Activity.
H. Griengl, E. Wanek, W. Schwarz, W. Streicher +2 more
19871 citations
Semantic Scholar
Synthesis of New Acyclic Nucleoside Analogs and Their Antiviral Properties Against Herpes Simplex Virus.
W. Streicher, G. Werner, B. Rosenwirth
19861 citations
Semantic Scholar
The Use of Cyclosporine , FKS 06 , and SDZ NIM 811 to Prevent CD 2 S-Quiescent Peripheral Blood Mononuclear Cells from Producing Human Immunodeficiency Virus
J. Borvak, C. Chou, G. V. Van Dyke, B. Rosenwirth +2 more
20100 citations
Semantic Scholar

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